Clinical trials: Health Volunteer
Healthy
Pedal Rate Influence on Oxygen Consumption in Eccentric
Nowadays, ECC exercise can be realized using various modalities that target small or large muscle masses in a segmentary or dynamic way.
- Trial name
- PRIOx (NCT02594657)
- Testing
- pedal rate on 50 RPM, pedal rate on 80 RPM
- Where
- France
- Volunteers
- 15 people, healthy volunteers welcome
- Sponsor
- University Hospital, Clermont-Ferrand
Psychological Stress, Mental Fatigue
Psychophysiological Effects of Green Exercise in Outdoor Green vs. Indoor Control
Core Purpose: Researchers want to learn if walking in an outdoor green environment helps people recover from mental tiredness and stress better than walking indoors.
- Conditions
- Psychological Stress, Mental Fatigue, Cognitive Dysfunction, Emotional Well-being
- Trial name
- GREEN-OI (NCT07379164)
- Testing
- Outdoor Green Group, Indoor Control Group
- Where
- China
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- Lincoln University College
Elderly Volunteers
Characterization of Fecal Microbiota in a Population Aged 50 to 75 Years Targeted by Seasonal Vaccination
The goal of this interventional study is to constitute a biological samples collection collected from healthy elderly volunteers and used for scientific purposes.
- Trial name
- FIFTY+ (NCT05972590)
- Testing
- Biological samples collection (blood + feces)
- Where
- France
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Bioaster
Aging, Facial Aging
Artificial Intelligence-Based Health Assessment From Face Photographs - Healthy Volunteer Study
The investigators aim to examine how FaceAge estimates (a measure of biological age based on facial features) change across different time points and identify factors that may influence these changes.
- Trial name
- FaceAge (NCT07719049)
- Where
- United States
- Volunteers
- 10,000 people, healthy volunteers welcome
- Sponsor
- Brigham and Women's Hospital
Psychological Well-being, Caregiver Burden of Caregivers
The Young Ambassadors Supporting Caregivers Program
This RCT will provide preliminary evidence on effective training for young adult volunteers to support older adult caregivers, addressing Hong Kong's aging crisis and caregiver burden. The objectives of this study include: 1.
- Trial name
- YASC (NCT07118774)
- Testing
- Behavioral: mindfulness and compassion training, Behavioral: caregiver skills training, Behavioral: Communication skills training
- Volunteers
- 120 people, healthy volunteers welcome
- Sponsor
- The University of Hong Kong
Smoking, Healthy Volenteers
Evaluation of GCF MMP-1, -8 and Growth Factor Levels in Smokers With Periodontal Health
Increased levels of cytokines in GCF have been demonstrated in smoker subjects with chronic periodontitis. It is not surprising that increased levels of inflammation associated molecules in GCF has been observed in smokers with…
- Trial name
- NCT02014857
- Testing
- Gingival Crevicular Fluid Sampling
- Where
- Turkey (Türkiye)
- Volunteers
- 32 people, healthy volunteers welcome
- Sponsor
- Ege University
Health Volunteer
A Single and Multiple Ascending Doses Study to Evaluate the Safety and Pharmacokinetics of RBD5044
This is a randomized, double-blind, placebo-controlled phase I study to evaluate the safety, tolerability, PK profiles and PD effect of single and multiple ascending doses of subcutaneously administered RBD5044 in healthy…
- Trial name
- NCT05539651
- Testing
- RBD5044
- Where
- Australia
- Volunteers
- 72 people, healthy volunteers welcome
- Sponsor
- Suzhou Ribo Life Science Co. Ltd.
Gastrointestinal Diseases
Probiotics Improve Health Young Volunteers' Gut Microbiota
The goal of this clinical trial is to evaluate whether daily supplementation with the probiotic Bifidobacterium breve BBr60 can improve metabolic, gastrointestinal, and emotional health in healthy adult volunteers aged 19 to 45…
- Trial name
- NCT06196892
- Testing
- Probiotic BBr60
- Where
- China
- Volunteers
- 109 people, healthy volunteers welcome
- Sponsor
- Wecare Probiotics Co., Ltd.
Air Pollution
Health Effects of Repeated Exposure to Low Levels of Concentrated Ambient Particles in Healthy Young Volunteers
Purpose: To determine whether 3-day consecutive exposures to levels of fine particulate matter (PM2.5) that are close to the current 24-hr national standard will cause changes in inflammatory and cardiopulmonary endpoints in…
- Trial name
- NCT05323240
- Testing
- PM exposure, Filtered air exposure
- Where
- United States
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- U.S. EPA Human Studies Facility
Endogenous and Esophageal Sensitivity
The Effect of Naloxone and Methylnaltrexone on Esophageal Sensitivity in Health
The aim of this study was to investigate the effect of naloxone (IV or IM administration) and methylnaltrexone (subcutaneous administration) on esophageal sensitivity, in a group of healthy volunteers in order to evaluate the…
- Trial name
- NCT03014843
- Testing
- Naloxone, Methylnaltrexone Bromide
- Volunteers
- 12 people, healthy volunteers welcome
- Sponsor
- Universitaire Ziekenhuizen KU Leuven
Schistosomiasis, Health Education
Health Education Model Led by Community Health Volunteers.
The goal of this intervention study is to investigate the level of knowledge, attitudes, and behaviors of students on schistosomiasis in Pemba Island.
- Trial name
- NCT06312462
- Testing
- health education
- Where
- Tanzania
- Volunteers
- 978 people, healthy volunteers welcome
- Sponsor
- Pemba Ministry of Health Zanzibar
Healthy Volunteers
Tolerability of a Modified Health-Dx
Single Blind, Randomized Control Study is designed to evaluate the tolerability of the Celero Systems' modified Health-Dx™ (mHDx) capsule.
- Trial name
- NCT06240650
- Testing
- modified Health- Dx™ (mHDx) study capsule, modified Health- Dx™ (mHDx) control capsule
- Where
- United States
- Volunteers
- 10 people, healthy volunteers welcome
- Sponsor
- Celero Systems, Inc.
Health
Bioequivalence Study Between UI009 and UIC202005 in Healthy Subjects
A Randomized, Open-label, Single-dosing, 2x2 Crossover Study to Evaluate Bioequivalence After Dry-powder Inhalation of UIC202005 or UI009 in Healty Volunteers
- Trial name
- NCT07110740
- Testing
- UI009, UIC202005
- Where
- South Korea
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Korea United Pharm. Inc.
Healthy Subjects
Safety and Tolerance Study of IBI355 in Health Volunteers
This study is being done to find out if IBI355 is safe and tolerance in health volunteers. The study will test increasing single doses of IBI355 given to adult health volunteers.
- Trial name
- NCT06110338
- Testing
- IBI355
- Where
- China
- Volunteers
- 53 people, healthy volunteers welcome
- Sponsor
- Innovent Biologics (Suzhou) Co. Ltd.
Health Volunteers
An Open-Label, Single-Dose, Mass-Balance Study to Assess the Disposition of 14C-Labeled PRT054021 in Healthy Male Subjects
This is a open label, single center, single oral dose, study of PRT054021, in healthy subjects.
- Trial name
- NCT01765855
- Testing
- Betrixaban single oral dose
- Volunteers
- 5 people, healthy volunteers welcome
- Sponsor
- Portola Pharmaceuticals
Healthy
Genetic and Epigenetic Mechanisms Underlying Cocoa Health Benefits
Evaluate if gene expression changes in SOD2 explain the health benefits of high polyphenols cocoa
- Trial name
- NCT02292576
- Testing
- Cocoa Pure
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- Société des Produits Nestlé (SPN)
Healthy Volunteers, Physical Fitness
Effects of 8-Week Mat Pilates and Reformer Pilates Exercises on Functional Movement Screen Scores and Joint Range of Motion in Recreationally Active Males
The goal of this clinical trial is to compare how 8 weeks of Mat Pilates and Reformer Pilates affect movement quality and joint flexibility in active young men.
- Trial name
- PILATES-FMS (NCT07869862)
- Testing
- Reformer Pilates Training, Mat Pilates Training
- Where
- Turkey (Türkiye)
- Volunteers
- 36 people, healthy volunteers welcome
- Sponsor
- Tokat Gaziosmanpasa University
Cognition, Multiomics
Probiotic Research: Open-label Functional Intervention and Longitudinal Evaluation in Healthy Adults
This study is a pre-post, open-label cohort study designed to investigate how a food-grade probiotic supplement affects biological measurements and wellbeing in healthy adults.
- Conditions
- Cognition, Multiomics, Microbiome Analysis, Metabolome
- Trial name
- PROFILE (NCT07457242)
- Testing
- Probiotic Supplementation (Lactobacillus plantarum)
- Volunteers
- 180 people, healthy volunteers welcome
- Sponsor
- OneCarbon
Health Volunteers
Study To Evaluate The Effect Of Multiple Doses of CTP-543 On The Pharmacokinetics Of Single Doses of Midazolam In Healthy Subjects
This is a single center, Phase 1, open-label, fixed-sequence, drug-drug interaction study to determine the effect of CTP-543 on the pharmacokinetics (PK) of midazolam in healthy adult subjects
- Trial name
- NCT05467709
- Testing
- Midazolam, CTP-543
- Where
- United States
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- Concert Pharmaceuticals
Loneliness, Mental Health
Reducing Loneliness Among Older Adults in Hong Kong by Volunteer-delivered Mindfulness and Behavioral Activation Intervention
This study aims to recruit and train retirees and young people to be volunteers who will deliver the layperson-delivered, telephone-based behavioral activation and mindfulness intervention to older adults.
- Trial name
- NCT07283549
- Testing
- Tele-BA, Tele-MF, Tele-BF
- Where
- Hong Kong
- Volunteers
- 251 people, healthy volunteers welcome
- Sponsor
- Education University of Hong Kong