Clinical trials: Health Volunteers
Health Volunteer
Clinical Study of Recombinant Humanized CTLA-4-FC Fusion Protein Injection in Healthy Subjects
This is a single-center, randomized, double-blind, does-escalation Phase I Clinical Study that aim to evaluate the tolerability, safety and PK Characteristics of recombinant humanized CTLA-4-FC fusion protein injection in Healthy…
- Trial name
- NCT05256719
- Testing
- Recombinant human CTLA-4-FC fusion protein for injection 1mg/kg, Recombinant human CTLA-4-FC fusion protein for injection 2.5mg/kg, Recombinant human CTLA-4-FC fusion protein for injection 5mg/kg
- Where
- China
- Volunteers
- 46 people, healthy volunteers welcome
- Sponsor
- Beijing VDJBio Co., LTD.
Healthy Subjects
Clinical Trial In Healthy Volunteers And Health Elderly Volunteers To Evaluate The Safety, Tolerability And Blood Concentration After Single And Multiple Escalating Oral Doses Of PF-06751979.
This study will test the safety, tolerability and blood concentrations of single and multiple oral doses of PF-06751979 in health subjects and healthy elderly subjects.
- Trial name
- NCT02793232
- Testing
- PF-06751979 single dose, PF-06751979 multiple ascending dose, PF-06751979 multiple dose
- Where
- Belgium
- Volunteers
- 46 people, healthy volunteers welcome
- Sponsor
- Pfizer
Healthy Volunteers
A Randomized Study to Evaluate the Effects of CTP-543 on the QT/QTc Intervals in Health Volunteers
This is a four-arm, randomized, crossover, placebo and active controlled study to evaluate of the effect of therapeutic and supratherapeutic doses of CTP-543 on the QT/QTc intervals in healthy volunteers
- Trial name
- NCT05192369
- Testing
- CTP-543, Moxifloxacin
- Where
- United States
- Volunteers
- 48 people, healthy volunteers welcome
- Sponsor
- Concert Pharmaceuticals
Pulmonary Hypertension, COPD
Integrating ePReBMs From Phoenix in Respiratory Diseases
Participants with respiratory disease experience often a worsening of their condition, with increasing symptoms such as cough and shortness of breath.
- Conditions
- Pulmonary Hypertension, COPD, Interstitial Lung Disease, Healthy Volunteers
- Trial name
- NCT05827302
- Testing
- Health Gauge AI-Based Wearable Device - Model: Phoenix
- Where
- Canada
- Volunteers
- 7 people, healthy volunteers welcome
- Sponsor
- University of Alberta
Healthy
Safety, Tolerability and Pharmacokinetics of FTP-198 Tablet in Healthy Chinese Volunteers
This is a Phase I, single-dose escalation clinical trial for FTP-198 conducted in chinese healthy volunteers. The safety, tolerability, food-impact and pharmacokinetics of FTP-198 tablet in healthy volunteers will be evaluated…
- Trial name
- FTP-198 (NCT04687813)
- Where
- China
- Volunteers
- 31 people, healthy volunteers welcome
- Sponsor
- Haisco Pharmaceutical Group Co., Ltd.
Healthy Volunteers
Influence of a Modified Ramadan Fasting on Health and Well-being in Healthy Muslims - a Randomised Controlled Trial
In this study the investigators will test the impact of a modified Ramadan Fasting regimen on health and well-being. The 2016 Ramadan is around summer solstice in Germany making it one of the most challenging fasting periods for…
- Trial name
- Ramadan_16 (NCT02775175)
- Testing
- Modified Ramadan Fasting
- Where
- Germany
- Volunteers
- 114 people, healthy volunteers welcome
- Sponsor
- Universität Duisburg-Essen
Healthy Volunteer Study
Smart Blister Packaging and Mobile Application to Monitor and Support Medication Adherence: a Two-arm Usability Study
Many people struggle to take their medications as prescribed, which can lead to poor health outcomes and increased healthcare costs.
- Trial name
- SMART-BLISTER (NCT07099612)
- Testing
- MEMS® Mobile smartphone application, Cere®Pak smart blister pack
- Where
- Netherlands
- Volunteers
- 36 people, healthy volunteers welcome
- Sponsor
- University Medical Center Groningen
Health Volunteers
Study to Evaluate Multiple Doses of Fluconazole, a CYP3A4 and CYP2C9 Inhibitor, on the Pharmacokinetics of CTP-543 in Healthy Subjects
A single center, Phase 1, open-label, fixed-sequence, drug-drug interaction study to evaluate the effect of multiple doses of Fluconazole, a CYP3A4 and CYP2C9 inhibitor, on the pharmacokinetics (PK) of CTP-543 in healthy subjects
- Trial name
- NCT05478772
- Testing
- CTP-543, Fluconazole
- Where
- United States
- Volunteers
- 18 people, healthy volunteers welcome
- Sponsor
- Concert Pharmaceuticals
Safety, Tolerability
A First-in-Human SAD and MAD Study in HV to Evaluate Oral YR011 Tablet
This is a Phase I clinical trial (protocol number: YR-011-B07) sponsored by Hangzhou Yirui Pharmaceutical Technology Co., Ltd., focusing on the novel oral small-molecule drug YR011 (active ingredient: PA032, a Kv1.3 channel…
- Conditions
- Safety, Tolerability, Pharmacokinetic
- Trial name
- NCT07878481
- Testing
- Kv1.3 potassium channel blocker (PA032, investigational oral small-molecule drug)
- Volunteers
- 64 people, healthy volunteers welcome
- Sponsor
- Hangzhou Yirui Pharmaceutical Technology Co., Ltd
Elderly Volunteers
Characterization of Fecal Microbiota in a Population Aged 50 to 75 Years Targeted by Seasonal Vaccination
The goal of this interventional study is to constitute a biological samples collection collected from healthy elderly volunteers and used for scientific purposes.
- Trial name
- FIFTY+ (NCT05972590)
- Testing
- Biological samples collection (blood + feces)
- Where
- France
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Bioaster
Health Adult Subjects
A Study to Evaluate ENERGI-F705 Tablets in Healthy Volunteers
To evaluate the safety, the tolerability, pharmacokinetics (PK), and pharmacodynamic (PD) of ENERGI-F705 Tablets in healthy subjects.
- Trial name
- NCT07650383
- Testing
- ENERGI-F705 Tablets 60 mg, ENERGI-F705 Tablets 120 mg, Vehicle Control
- Where
- Taiwan
- Volunteers
- 24 people, healthy volunteers welcome
- Sponsor
- Energenesis Biomedical Co., Ltd.
Healthy Volunteers, Persons With no Known Significant Health Problems
Effectivity of Slackline-Training in Physiotherapy
Slacklines have been established in the last few years as a training equipment in sports such as climbing, skiing and others to increase postural control.
- Trial name
- NCT02218086
- Testing
- Slackline, Wobbling Board, Pre-training
- Where
- Switzerland
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- THIM - die internationale Hochschule für Physiotherapie
Healthy Volunteers, Aging, Healthy
Intervention Program for Psychological Well-Being in Institutionalized Older Adults Through Virtual Reality
This randomized controlled trial (N = 60) evaluates the acceptability and efficacy of an immersive virtual reality (IVR) intervention designed to enhance psychological well-being in older adults without cognitive impairment…
- Trial name
- RRCE (NCT07884435)
- Testing
- Active IVR Group, Passive IVR Goup
- Where
- Spain
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Francisco Antonio Nieto Escámez
Healthy, Drug Interaction
Single Dose Study Of The Effect Of Cyclosporine On The Pharmacokinetics Of PF-04991532 In Health Volunteers
The primary purpose of this study is to evaluate the pharmacokinetics, safety and tolerability of a single dose of PF-04991532 in healthy adult subjects with and without co-administration of cyclosporine.
- Trial name
- NCT01370343
- Testing
- PF-04991532 alone, PF-04991532 + cyclosporine
- Where
- Belgium
- Volunteers
- 12 people, healthy volunteers welcome
- Sponsor
- Pfizer
Metabolic Syndrome, HEALTHY VOLUNTEERS
Promoting Immune Health by Intermittent Fasting: a Pilot Study
The goal is to study the direct effects of long-term intermittent fasting on immune cell populations in the blood, combined with analyses of systemic metabolic fitness and inflammatory activation of leukocytes.
- Conditions
- Metabolic Syndrome, HEALTHY VOLUNTEERS, Time Restricted Feeding, Insulin Resistance
- Trial name
- TIGER (NCT05898360)
- Testing
- Time Restricted Eating, normal diet
- Where
- Netherlands
- Volunteers
- 24 people, healthy volunteers welcome
- Sponsor
- Academisch Medisch Centrum - Universiteit van Amsterdam (AMC-UvA)
Type2 Diabetes Mellitus
Continuous Multiple Dose PB-119 Injection in Health Volunteers
This is an open label, multiple dose study, pharmacokinetic and pharmacodynamics studies will be performed at the same time with tolerability study.
- Trial name
- NCT03062774
- Testing
- PB-119 injection
- Where
- China
- Volunteers
- 36 people, healthy volunteers welcome
- Sponsor
- PegBio Co., Ltd.
Health
Bioequivalence Study Between UI009 and UIC202005 in Healthy Subjects
A Randomized, Open-label, Single-dosing, 2x2 Crossover Study to Evaluate Bioequivalence After Dry-powder Inhalation of UIC202005 or UI009 in Healty Volunteers
- Trial name
- NCT07110740
- Testing
- UI009, UIC202005
- Where
- South Korea
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Korea United Pharm. Inc.
Constipation - Functional
Safety, Tolerability and Pharmacokinetics of CDD-2101 in Health Volunteers
This is a single-center, randomized, double-blind, placebo-controlled, single-dose study to confirm the safety, tolerability and pharmacokinetic profile of CDD-2101 in healthy subjects.
- Trial name
- NCT06570668
- Testing
- CDD-2101
- Where
- United States
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- Centre for Chinese Herbal Medicine Drug Development Limited
Antiplatelet Drug
Antiplatelet Thrombolysin (Anfibatide) Phase 1 Clinical Trial in Healthy Volunteers
This is a phase 1, dose-escalation, and multidose study, aiming to investigate the tolerability, safety and pharmacokinetics of Anfibatate in healthy subjects.
- Trial name
- NCT04404790
- Testing
- Anfibatide 5 IU/60kg, Anfibatide 5 IU/60kg +0.002 IU/kg/h, Anfibatide 5 IU/60kg +0.004 IU/kg/h
- Where
- China
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- Lee's Pharmaceutical Limited
Chronic Kidney Disease
Effectiveness of Integrated Care on Delaying Chronic Kidney Disease Progression in Rural Communities of Thailand
If primary health-care officers and Villages Health Volunteers (VHVs) be trained to render proper CKD care, it is interesting if their intimate relationship and commitment to their responsible village households will result in…
- Trial name
- ESCORT (NCT01978951)
- Testing
- Integrated Chronic Kidney Disease care, Conventional CKD care
- Where
- Thailand
- Volunteers
- 443 people
- Sponsor
- Bhumirajanagarindra Kidney Institute, Thailand