Clinical trials: Health Volunteers
Healthy Volunteers
Platform for Clinical Trials in Nutrition and Health
Despite the known link between dietary patterns and disease, it has been observed that the specific response of each individual to dietary components highly varied, and this may limit the impact of the nutritional interventions…
- Trial name
- GENYALPlatform (NCT04067921)
- Where
- Spain
- Volunteers
- 1,963 people
- Sponsor
- IMDEA Food
Mental Health Impairment, Peer Group
Paths to Everyday Life (PEER) - a Community-based Peer Support Intervention
The aim of this randomized, two-arm, investigator initiated, multi municipal, parallel-group superiority trial is to compare the effect on self-reported personal recovery of the following interventions: (1) 10-week group-based…
- Conditions
- Mental Health Impairment, Peer Group, Mental Health Disorder, Problems Psychosocial
- Trial name
- PEER (NCT04639167)
- Testing
- Paths to everyday life (PEER)
- Where
- Denmark
- Volunteers
- 299 people, healthy volunteers welcome
- Sponsor
- Amager Hospital
Healthy
PET Imaging of Peripheral Benzodiazepine Receptors
This study will use positron emission tomography (PET) to measure a receptor in the brain that is involved in inflammation. It will test two radioactive chemicals used in the procedure to see if the newer chemical, [(11)C]B, is…
- Trial name
- NCT00696371
- Where
- United States
- Volunteers
- 15 people
- Sponsor
- National Institute of Mental Health (NIMH)
Healthy Volunteer
Following of Atmospheric Pollution Exposure During Pregnancy and Effects on Health
The SEPAGES couple-child cohort is coordinated by an Inserm (French National Institute of Health and Medical Research) team of environmental epidemiology.
- Trial name
- SEPAGES-1337 (NCT02852499)
- Testing
- Urine sampling, Carry a GPS and BET, Carry pollution sensor
- Where
- France
- Volunteers
- 1,010 people, healthy volunteers welcome
- Sponsor
- University Hospital, Grenoble
Healthy
Pedal Rate Influence on Oxygen Consumption in Eccentric
Nowadays, ECC exercise can be realized using various modalities that target small or large muscle masses in a segmentary or dynamic way.
- Trial name
- PRIOx (NCT02594657)
- Testing
- pedal rate on 50 RPM, pedal rate on 80 RPM
- Where
- France
- Volunteers
- 15 people, healthy volunteers welcome
- Sponsor
- University Hospital, Clermont-Ferrand
Healthy
Forearm Immobilization, Metabolic Health, and Nutrition
The present study will investigate the impact of dietary branched chain amino acid restriction on muscle atrophy, insulin sensitivity and muscle protein synthesis following short-term forearm immobilization
- Trial name
- NCT04626401
- Testing
- Forearm immobilization
- Where
- United Kingdom
- Volunteers
- 24 people, healthy volunteers welcome
- Sponsor
- University of Exeter
Melanoma (Skin Cancer), Health Volunteers
Study of Melanoma-Resistant PET Monitoring Based on Key Rate-limiting Enzymes for Fatty Acid Metabolism in Healthy Volunteers
This is a small-sample safety study involving 15 healthy volunteers who were divided into groups and underwent 68Ga-ACC-DE, 68Ga-FASN-DE, and 68Ga-ACLY-DE PET/CT imaging for safety, biodistribution, and radiation dosimetry…
- Conditions
- Melanoma (Skin Cancer), Health Volunteers, PET / CT
- Trial name
- NCT07114172
- Testing
- 68Ga-ACC-DE/68Ga-FASN-DE/68Ga-ACLY-DE PET/CT
- Volunteers
- 15 people, healthy volunteers welcome
- Sponsor
- Xijing Hospital
Volunteers
Cardiometabolic Health and Inflammatory Resolution
The aim of this study is to determine how inflammatory resolution impacts cardiometabolic health and disease in subjects that are either lean (18.5-24.9 kg/m2), overweight (25.0-29.9 kg/m2) or obese (>30.0 kg/m2).
- Trial name
- REX (NCT04256330)
- Where
- Sweden
- Volunteers
- 200 people
- Sponsor
- Göteborg University
Sarcopenia, Sarcopenia in Elderly
The Effect of Volunteer-Engaged Lifestyle Optimisation Via ICOPE on Sarcopenia in Older Adults (VELO-S)
Sarcopenia prevention and management are highly prioritised goals in the Healthy Ageing agenda. The study aims to: 1) evaluate the effects of the digital-enhanced, volunteer-engaged collaborative care pathway to improve…
- Conditions
- Sarcopenia, Sarcopenia in Elderly, Fall Prevention in Healthy Aging, Frailty Syndrome
- Trial name
- NCT07345832
- Testing
- Volunteer-Engaged Lifestyle Optimisation via ICOPE for Sarcopenia program (VELO-S), Attention control
- Where
- Hong Kong
- Volunteers
- 200 people
- Sponsor
- The University of Hong Kong
Healthy Volunteers Only
Educational Impact of the NLM/National Area Health Education Center Organization (NAO) Project-SHARE Based Teen Health Information Literacy Curriculum
Background: The Teen Health Information Literacy Project is an after-school program for high school students. It gives them skills to access valid and reliable health data. It also aims to grow young health advocates.
- Trial name
- NCT02769988
- Where
- 6 sites in United States
- Volunteers
- 127 people, healthy volunteers welcome
- Sponsor
- National Library of Medicine (NLM)
Cognition, Multiomics
Probiotic Research: Open-label Functional Intervention and Longitudinal Evaluation in Healthy Adults
This study is a pre-post, open-label cohort study designed to investigate how a food-grade probiotic supplement affects biological measurements and wellbeing in healthy adults.
- Conditions
- Cognition, Multiomics, Microbiome Analysis, Metabolome
- Trial name
- PROFILE (NCT07457242)
- Testing
- Probiotic Supplementation (Lactobacillus plantarum)
- Volunteers
- 180 people, healthy volunteers welcome
- Sponsor
- OneCarbon
Pharmacokinetic Analysis, Bioequivalence
Bioequivalence Study of Levetiracetam 1500 mg Coated Granules in Healthy, Male Subjects
Pivotal, single-dose, randomized, open-label, two-period, two-sequence, two-treatment, single-centre, crossover, bioequivalence study of Levetiracetam 1500 mg coated granules in sachet formulations and Keppra (Levetiracetam) 2 x…
- Conditions
- Pharmacokinetic Analysis, Bioequivalence, Health Adult Subjects
- Trial name
- NCT07393022
- Testing
- Levetiracetam 1500 mg, Keppra® 750 mg
- Where
- Canada
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- Desitin Arzneimittel GmbH
Conditionally Healthy Persons, Persons With a High Body Mass Index
Medico-ecological Monitoring ((CSM, MCTQ, SPAQ, PSQI, HRV, Spirometry; Anthropometry, BP) of the Different Population Groups (Students, Schoolchildren, Volunteers) in North Caucasus
Observational Clinical Trial of the chronotype, sleep quality, seasonal pattern, behavioral time preferences, the functional state of the body's regulatory systems and respiratory systems in individuals of different age groups…
- Trial name
- NCT04851080
- Testing
- Heart Rate Variability, Spirometry, Testing of psycho-physiological functions using four questionnaires
- Where
- Russia
- Volunteers
- 370 people, healthy volunteers welcome
- Sponsor
- Vladikavkaz Scientific Center of the Russian Academy of Sciences
Healthy Volunteer
OrthoEvidence Trial Assessing Japanese Knowledge Updates
The purpose of this randomized controlled trial is to clarify whether providing translated evidence summary (Advanced Clinical Evidence (ACE) reports from OrthoEvidence) will increase the access to the summary compared to…
- Trial name
- OTAKU (NCT05250622)
- Testing
- Japanese-translated evidence summaries (Advanced Clinical Evidence report from OrthoEvidence), English evidence summaries (Advanced Clinical Evidence report from OrthoEvidence)
- Where
- Canada
- Volunteers
- 105 people, healthy volunteers welcome
- Sponsor
- McMaster University
Human Health in Extreme Conditions
CHOICE KERGUELEN 1: Consequences of Longterm Confinement on Immunity in the Sub-Antarctic Islands: Inclusion of Volunteers Before Departure to the Kerguelen Islands
Living for long periods in extreme environments-like Antarctic research stations or space missions-can have a significant impact on human health, especially on the immune system.
- Trial name
- NCT07065253
- Testing
- blood ponction, urines collection, hair collection
- Where
- France
- Volunteers
- healthy volunteers welcome
- Sponsor
- University Hospital, Angers
Healthy Volunteers
Effects of Museum Visits on Neurocognitive Well-being
The effects of art on health and well-being have been the subject of increasing exploration in recent years. In 2019, the World Health Organization proposed a literature review analyzing the links between art, health (defined as…
- Trial name
- ABC (NCT06515041)
- Testing
- brain well-being
- Where
- France
- Volunteers
- 200 people, healthy volunteers welcome
- Sponsor
- University Hospital, Caen
Anhedonia in Healthy Volunteers, Older Adults (50-90 Years)
A Study of Psychedelics in Healthy Older Adults With Low Well-being
This study is being conducted to understand changes in brain activity following administration of two different drugs (Psilocybin and Dextromethorphan) in older adults with low well-being.
- Trial name
- OAD1 (NCT07386730)
- Testing
- Psilocybin (drug), Dextromethorphan (DXM)
- Where
- United States
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- Jennifer Mitchell
Health Volunteers, Huntington Disease
A Study to Evaluate Sigma-1 and Dopamine-2 Receptor Occupancy by Pridopidine in the Human Brain of Healthy Volunteers and in Patients With Huntington's Disease
The purpose of this study is to demonstrate engagement of pridopidine with S1R and D2R (optional) in the living human brain. No formal statistical analysis will be conducted
- Trial name
- NCT03019289
- Testing
- pridopidine (90 mg)
- Where
- Germany
- Volunteers
- 23 people, healthy volunteers welcome
- Sponsor
- Prilenia
Healthy Subjects
Pharmacokinetics Study of CJ-40001 and NESP® After Single Dose Administration in Health Male Volunteers
The purpose of this study is to compare the pharmacokinetics and safety after a single subcutaneous or intravenous administration of CJ-40001 and NESP® in healthy male volunteers.
- Trial name
- NCT03542916
- Testing
- CJ-40001 60ug, NESP 60ug
- Where
- South Korea
- Volunteers
- 56 people, healthy volunteers welcome
- Sponsor
- HK inno.N Corporation
Health Volunteer
In Vivo Mass Balance Study of [14C]Hemay005
This study is a single-center, single-dose, non-randomized, open-label study to evaluate the in vivo mass balance of [14C]Hemay005. Six healthy male subjects are planned to be enrolled.
- Trial name
- NCT05468645
- Testing
- [14C]Hemay005
- Where
- China
- Volunteers
- 6 people, healthy volunteers welcome
- Sponsor
- Ganzhou Hemay Pharmaceutical Co., Ltd