Clinical trials: Health-Related Behavior
Postoperative Pain, Anxiety
The Effect of Coaching Strategy on Some Patient Outcomes After Total Knee Arthroplasty Surgery
Total knee arthroplasty (TKA); It is frequently applied to adults, especially those over the age of 55. Total knee arthroplasty surgery is among the surgeries with a high satisfaction rate for the patient, although complications…
- Conditions
- Postoperative Pain, Anxiety, Self Efficacy, Patient Satisfaction
- Trial name
- NCT04683588
- Testing
- Nursing Coaching
- Where
- Turkey (Türkiye)
- Volunteers
- 72 people, healthy volunteers welcome
- Sponsor
- Selcuk University
Smoking Cessation, Nicotine Addiction
Nicotine Receptor Levels and Smoking Cessation
The investigators propose to use positron emission tomography (PET) imaging to determine whether nicotinic receptor availability at pretreatment predicts smoking cessation success.
- Trial name
- NCT01788943
- Where
- United States
- Volunteers
- 24 people, healthy volunteers welcome
- Sponsor
- University of Pennsylvania
Sedentary Lifestyle, Workplace
Effectiveness of a Workplace "Sit Less and Move More" Web-based Program in Spanish Office Employees (Walk@WorkSpain)
This study assesses the short and mid-term impacts of a workplace web-based intervention (Walk@WorkSpain, W@WS) on self-reported occupational sitting time, step counts, activity-related energy expenditure, physical risk factors…
- Conditions
- Sedentary Lifestyle, Workplace, Quality of Life, Intervention Study
- Trial name
- W@WS (NCT02960750)
- Testing
- A workplace "sit less and move more" web-based program for Spanish office employees, Active Comparison group
- Where
- 4 sites in Spain
- Volunteers
- 264 people, healthy volunteers welcome
- Sponsor
- University of Vic - Central University of Catalonia
Adherence, Tobacco Use Cessation
Smoking Cessation for Young Adults Who Binge Drink - 1
The purpose of this study is develop and test the success of a new smoking cessation intervention that includes a component to eliminate binge drinking.
- Conditions
- Adherence, Tobacco Use Cessation, Alcohol & Drug Use, Nicotine Transdermal System
- Trial name
- NCT00218452
- Testing
- Lifestyle counseling
- Where
- 3 sites in United States
- Volunteers
- 41 people, healthy volunteers welcome
- Sponsor
- Mayo Clinic
Tobacco Use Cessation, Tobacco Use Disorder
Treating Nicotine Dependence in Schizophrenic Individuals: Effectiveness of Bupropion - 1
Schizophrenic individuals are typically nicotine dependent smokers who find it difficult to quit smoking. The purpose of this study is to determine the effectiveness of bupropion SR (commonly known as Zyban) in combination with a…
- Conditions
- Tobacco Use Cessation, Tobacco Use Disorder, Schizophrenia
- Trial name
- NCT00124683
- Testing
- Bupropion, nicotine transdermal patch
- Volunteers
- 59 people, healthy volunteers welcome
- Sponsor
- National Institute on Drug Abuse (NIDA)
Nicotine Dependence, Smoking Cessation
Accelerated iTBS in Smoking Cessation
Cigarette smoking is one of the foremost causes of preventable disease and premature death. In 2014, 68% of adult smokers wanted to quit smoking and in 2017, 55.1% of adult smokers had made a quit attempt.
- Trial name
- NCT05271175
- Testing
- Active intermittent theta burst stimulation
- Where
- Cyprus
- Volunteers
- 104 people, healthy volunteers welcome
- Sponsor
- Cyprus rTMS Center
HPV-related Cancers, HPV Vaccination
Trial in HPV Prevention for the U.S. Vietnamese Community
The purpose of the HERO study is to leverage the Multiphase Optimization Strategy (MOST) framework to conduct a pilot trial testing four different intervention components (expert video, self-persuasion, narrative storytelling…
- Trial name
- HERO (NCT07637630)
- Testing
- Expert Video, Self-persuasion, Narrative Storytelling
- Where
- United States
- Volunteers
- 96 people, healthy volunteers welcome
- Sponsor
- Northwestern University
Pelvic Girdle Pain, Physical Activity
WOMENinMOTION An Intervention Model for Pelvic Girdle Pain
The overall aim is to educate women to handle common pregnancy-related pain experiences to facilitate healthy life-long physical activity habits and prevent chronic pain.
- Trial name
- WIMPGP (NCT07158957)
- Testing
- knowledge, motivation for behavioral change
- Where
- 2 sites in Sweden
- Volunteers
- 592 people, healthy volunteers welcome
- Sponsor
- Vastra Gotaland Region
Hepatitis B, Human Papilloma Virus
Managing Hepatitis B (Hep. B) and Human Papilloma Virus (HPV) Related Cancers and Mental Health.
Aim: The main goal of this quantitative epidemiological observational study is to determine the prevalence of Human Papilloma Virus (HPV) infection and Hepatitis B (Hep B) immunity amongst women of childbearing age.
- Conditions
- Hepatitis B, Human Papilloma Virus, Mental Health Issue, Cancer Liver
- Trial name
- NCT06786429
- Testing
- Gardasil 9 vaccine, Hepatitis B Virus Vaccine(HBV), Cognitive Behavioral Therapy
- Volunteers
- 2,140 people, healthy volunteers welcome
- Sponsor
- Eunice Dube
Cataract Extraction, Phacoemulsification
A Study Comparing Two Monofocal, Aspheric, Hydrophobic Acrylic Intraocular Lenses: the Alcon CLAREON® and the Abbott Medical Optics PCB00
This is a bilateral randomised controlled study to compare visual performance, refractive outcome, forward light scatter, patient satisfaction and objective measurement of glistenings following insertion of two monofocal…
- Conditions
- Cataract Extraction, Phacoemulsification, Glistenings, Intraocular Lens Implant
- Trial name
- NCT03364972
- Testing
- Cataract surgery
- Where
- United Kingdom
- Volunteers
- 145 people, healthy volunteers welcome
- Sponsor
- Guy's and St Thomas' NHS Foundation Trust
Health Behavior
Wearable Emotion Prosthetics for Post Traumatic Stress Disorder
Involuntary stress reactions including hyper-reactivity and dissociation are key diagnostic features of many psychiatric disorders, are difficult to treat, and predict poor outcomes in conventional and neurobehavioral…
- Trial name
- EP-PTSD (NCT03529981)
- Testing
- Tuned Vibroacoustic Stimulation (TVS), no active intervention
- Where
- United States
- Volunteers
- 16 people, healthy volunteers welcome
- Sponsor
- University of Pittsburgh
Pregnancy, High Risk, Depression, Postpartum
The Effect of Stress Reduction Program on Pregnancy Process and Mental Health in High Risk Pregnant Women
Introduction Pregnancy and giving birth to an infant is a physiological process as well as it is also a transition of life, and a stressful period of time with a significance in the life of woman.
- Conditions
- Pregnancy, High Risk, Depression, Postpartum, Anxiety in Pregnancy, Stress Disorder
- Trial name
- NCT05573009
- Testing
- cognitive behavioral approach-based stress reduction program
- Where
- Turkey (Türkiye)
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Istanbul University
Tobacco Dependence, Smoking Cessation
Combination of Nicotine Replacement Therapy (NRT) and Varenicline to Increase Cessation of Tobacco (CONVICT Study)
Varenicline and nicotine replacement therapy (NRT) are both effective smoking cessation treatments. Anecdotally smokers who are finding their quit attempt difficult have reported benefiting from adding NRT to varenicline.
- Trial name
- CONVICT (NCT01184664)
- Testing
- Nicotine Patch, Varenicline
- Where
- 2 sites in United Kingdom
- Volunteers
- 117 people, healthy volunteers welcome
- Sponsor
- Queen Mary University of London
Adolescent Development, Adolescent Behavior
An Adolescent Health and Wellbeing Check-up Programme in Three African Cities (Y-Check)
This is a multi-country prospective intervention study, with a mixed-method process evaluation to assess the implementation, effects and short-term cost-effectiveness of Y-Check.
- Conditions
- Adolescent Development, Adolescent Behavior, Health-Related Behavior, Health Care Seeking Behavior
- Trial name
- Y-Check (NCT06090006)
- Testing
- Screening package, Psychosocial and mental health disorder screening, Alcohol, tobacco and substance use screening
- Where
- 3 sites in Ghana, Tanzania and 1 more
- Volunteers
- 6,000 people, healthy volunteers welcome
- Sponsor
- World Health Organization
Smoking
Glucobrassicin-Brussel Sprout Effect on D10 Phe Metabolism
To determine whether glucobrassicin-rich Brussels sprouts can favorably modify the metabolism of the polycyclic aromatic hydrocarbon deuterated phenanthrene ([D10]phe) in current and former smokers
- Trial name
- NCT02999399
- Testing
- Brussel Sprouts, Deuterated Phenanthrene
- Where
- United States
- Volunteers
- 39 people, healthy volunteers welcome
- Sponsor
- Masonic Cancer Center, University of Minnesota
Mental Health
Educational Intervention for Optimizing Adolescent Mental Health Screening and Treatment in Pediatric Residency
The purpose of this study is: 1) to assess pediatric resident knowledge of adolescent mental health; 2) to assess pediatric resident comfort level for screening, assessing, and treating mental health disorders in adolescents…
- Trial name
- NCT00768352
- Testing
- Educational intervention
- Where
- United States
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- Brooke Army Medical Center
Sexual Behavior, Conflict, Family
Heart to Heart: Testing a Sexual Health Training for Foster and Kinship Caregivers
Heart to Heart is a brief pregnancy prevention training program delivered to foster and kinship caregivers to prevent unintended pregnancy in foster youth.
- Conditions
- Sexual Behavior, Conflict, Family, Pregnancy Related, Sexually Transmitted Diseases
- Trial name
- NCT03331016
- Testing
- Heart to Heart Training
- Where
- 2 sites in United States
- Volunteers
- 62 people, healthy volunteers welcome
- Sponsor
- Seattle Children's Hospital
Mental Health Issue (E.G., Depression, Psychosis, Personality Disorder, Substance Abuse), Infant Development
Maternal Adversity, Vulnerability and Neurodevelopment
Maternal Adversity Vulnerability and Neurodevelopment (MAVAN) project is a prospective community-based, pregnancy and birth cohort of Canadian mother-child dyads.
- Conditions
- Mental Health Issue (E.G., Depression, Psychosis, Personality Disorder, Substance Abuse), Infant Development, Infant Behavior
- Trial name
- MAVAN (NCT03434457)
- Where
- Canada
- Volunteers
- 630 people, healthy volunteers welcome
- Sponsor
- Douglas Mental Health University Institute
Alcohol Use Disorder, Risk Behavior, Health
Alcohol Misuse, Gut Microbial Dysbiosis and PrEP Care Continuum: Application and Efficacy of SBIRT Intervention
This randomized control trial study among Pre-exposure prophylactic users (PrEP) aims to learn and determine the efficacy of Screening, brief intervention, and referral to treatment (SBRIT) in reducing the risk of alcohol use.
- Conditions
- Alcohol Use Disorder, Risk Behavior, Health, Dysbiosis, HIV Infections
- Trial name
- SEAL (NCT06005298)
- Testing
- Screening, Brief Intervention, Referral to Treatment (SBIRT)
- Where
- United States
- Volunteers
- 120 people, healthy volunteers welcome
- Sponsor
- Shirish S Barve
Posttraumatic Stress Disorder, Acute Post-Traumatic Stress Disorder
Prevention of Mental Health Problems in People Exposed to a Recent Highly Stressful Event.
This project evaluates the effectiveness of three intervention models for the prevention of mental health problems in people who have suffered a recent highly stressful event, through an experimental design, with a control group…
- Conditions
- Posttraumatic Stress Disorder, Acute Post-Traumatic Stress Disorder, Depressive Symptoms
- Trial name
- NCT04314115
- Testing
- Mindfulness, Systemic therapy, Cognitive behavioral therapy and positive psychology
- Where
- Chile
- Volunteers
- 160 people, healthy volunteers welcome
- Sponsor
- Universidad Santo Tomas, Chile