Clinical trials: Health-related Quality of Life
Denture, Complete
Measuring Quality of Life of Poly-amide Complete Dentures
Polymethyl methacrylate have been used since 1937 as a gold standard for a denture base material because of its several advantages as; good esthetics, adequate strength, easy repair and simple processing techniques.
- Trial name
- NCT03234803
- Testing
- poly-amide, poly-methyl methacrylate
- Volunteers
- 18 people
- Sponsor
- Cairo University
Inflammatory Disease, Immune System Disorder
Cross-condition Validation of the Steroid PRO
Testing a questionnaire about treatment with steroids for skin, lung or gastric conditions
- Conditions
- Inflammatory Disease, Immune System Disorder, Gastrointestinal Diseases, Dermatologic Disease
- Trial name
- NCT06314451
- Testing
- Cognitive Interview
- Where
- United Kingdom
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- University of the West of England
Partially Edentulous Mandible
Polyetheretherketone vs Cobalt-chromium Telescopic Removable Partial Denture in Kennedy Class I Patients Regarding Oral Health Related Quality of Life
Dentistry is a rapidly progressing field with innumerable advances taking place on a day to day basis. The application of newer technologies and materials has advanced the specialty of prosthodontics and the services rendered to…
- Trial name
- NCT03771248
- Testing
- peek telescopic partial denture
- Volunteers
- 20 people
- Sponsor
- Cairo University
Healthy, Constipation
Effect of a Fermented Milk Product With Probiotics Alone or in Combination With Fibers on Constipation Symptoms
First experimental study (Proof Of Concept) to investigate bowel function parameters on which a fermented milk product with probiotics alone or in association with fibers has a potential effect.
- Trial name
- NCT02461485
- Testing
- Fermented milk product containing Probiotics, Fermented Milk Product containing Probiotics + Fibers C, Fermented Milk Product containing Probiotics + Fibers W
- Where
- Ireland
- Volunteers
- 153 people, healthy volunteers welcome
- Sponsor
- Danone Global Research & Innovation Center
Prostatic Neoplasms
A Study to Investigate the Impact of Abiraterone Acetate and Enzalutamide on Health-related Quality of Life, Participant-Reported Outcomes, and Medical Resource Use in Metastatic Castration-resistant Prostate Cancer Participants
The purpose of this observational study of metastatic castration-resistant prostate cancer (mCRPC) participants is to explore whether or not there are differences between participants treated with abiraterone acetate and…
- Trial name
- AQUARiUS (NCT02813408)
- Where
- 26 sites in Denmark, France and 1 more
- Volunteers
- 226 people
- Sponsor
- Janssen Pharmaceutica N.V., Belgium
Cardiovascular Disease
Technology Dependency and Health-Related Quality of Life
This study will explore how people with an implanted cardioverter defibrillator (ICD) feel that dependence on this life-saving technology affects their health-related quality of life.
- Trial name
- NCT00022984
- Where
- United States
- Volunteers
- 125 people
- Sponsor
- National Institutes of Health Clinical Center (CC)
Oral Health Related Quality of Life
Turkish Validity and Reliability of Oral Health Impact on Daily Life Questionnaire
This study aimed to test Turkish validity and reliability of the Oral Health Impact on Daily Life Questionnaire (OHIDL) in adult endodontic patients.The questionnaire was translated and adapted into Turkish.
- Trial name
- NCT06117189
- Testing
- Questionnaire
- Where
- Turkey (Türkiye)
- Volunteers
- 222 people, healthy volunteers welcome
- Sponsor
- Recep Tayyip Erdogan University
Head and Neck Cancer, Skull Base--Cancer
HRQoL in Patients With Solid Tumors Treated With Hadrontherapy
The Quality of Life of patients treated with hadrontherapy is still limited. Two cohorts are established, they will be receiving specific standardized questionnaires to be evalutaed in their results.
- Conditions
- Head and Neck Cancer, Skull Base--Cancer, Brain Cancer
- Trial name
- HadroQoL (NCT05947149)
- Testing
- questionnaires administration
- Where
- Italy
- Volunteers
- 180 people
- Sponsor
- CNAO National Center of Oncological Hadrontherapy
Diabetes Mellitus, Type II
´Sit Less, Move More' at Work: mHealth Intervention on Office Employees With Diabetes Type 2.
The objective of the study is measuring the impact of a ´sit less, move more' mHealth intervention at work on the glycaemic control and anthropometric profile of office employees with diabetes type 2 (DT2) at short, mid and long…
- Trial name
- Walk@Work (NCT04092738)
- Testing
- Walk@WorkApp-Diab
- Where
- Spain
- Volunteers
- 368 people
- Sponsor
- Fundacio d'Investigacio en Atencio Primaria Jordi Gol i Gurina
Non Specific Low Back Pain
Vertical Oscillatory Pressure and Sustained Natural Apophyseal Glides in ow Back Pain
Among different spinal manual therapies, which have been reported to be effective in the management of LBP are Sustained Natural Apophyseal Glide (SNAGS) and Vertical Oscillatory Pressure (VOP) .
- Trial name
- VOP&SNAG (NCT05612308)
- Testing
- Vertical Oscillatory Pressure (VOP)
- Where
- Nigeria
- Volunteers
- 25 people
- Sponsor
- Obafemi Awolowo University
eHealth Literacy
Evaluation of Technology Acceptance and Electronic Health (Ehealth) Literacy of Patients Undergoing Radiotherapy
Evaluation of technology acceptance and digital health literacy (eHealth literacy) of patients undergoing radiotherapy. In addition, a qualitative survey of data on the patient journey and its influence on overall satisfaction…
- Trial name
- RO_eHEALTH (NCT06645496)
- Testing
- Evaluation of ehealth literacy
- Where
- Germany
- Volunteers
- 213 people
- Sponsor
- Charite University, Berlin, Germany
Chronic Fatigue Syndrome
Coenzyme Q10 Plus NADH Supplementation in Chronic Fatigue Syndrome/Myalgic Encephalomyelitis
The main aim of the study is to examine the effect of oral CoQ10 plus NADH (Reconnect®) supplementation twice daily for 8-weeks on the changes in fatigue perception, sleep disturbances, autonomic dysfunction and HRQoL assessed by…
- Trial name
- CONNeCT (NCT03186027)
- Testing
- Coenzyme Q10 plus NADH, phosphoserine plus vitamin C
- Where
- Spain
- Volunteers
- 282 people
- Sponsor
- Hospital Universitari Vall d'Hebron Research Institute
Necrotizing Soft Tissue Infection, Necrotizing Fasciitis
Immunoglobulin for Necrotizing Soft Tissue Infections: a Randomised Controlled Trial
The purpose of this study is to estimate the effect of intravenous polyspecific immunoglobulin G (IVIG) compared with placebo (saline) on the patient-reported outcome measure Physical Component Summary Score (PCS) of the SF-36 in…
- Conditions
- Necrotizing Soft Tissue Infection, Necrotizing Fasciitis, Gas Gangrene, Fournier Gangrene
- Trial name
- INSTINCT (NCT02111161)
- Testing
- IVIG (Privigen), Saline 0.9%
- Where
- Denmark
- Volunteers
- 100 people
- Sponsor
- Anders Perner
Seasonal Allergic Rhinitis
A Study Evaluating the Efficacy and Impact on Health-related Quality of Life of Levocetirizine in Adults With Seasonal Allergic Rhinitis
The study objective is to investigate the efficacy of levocetirizine in reducing symptoms associated with seasonal allergic rhinitis and in improving rhinitis-related Quality of Life
- Trial name
- NCT00621959
- Testing
- levocetirizine dihydrochloride
- Where
- 26 sites in United States
- Volunteers
- 596 people
- Sponsor
- UCB Pharma
Posttraumatic Stress Disorder, Depression
Self-Help Cognitive Processing Therapy (CPT)/Women Veterans Network (WoVeN) Study
Posttraumatic stress disorder (PTSD) can have significant impairment on aspects of mental well-being (MWB) including functioning, loneliness, physical health, and quality of life.
- Trial name
- NCT07250061
- Testing
- Self-Help Cognitive Processing Therapy, Women Veterans Network (WoVeN), Treatment as Usual
- Where
- United States
- Volunteers
- 100 people
- Sponsor
- Boston University
Genital Neoplasms, Female
Characterization of the Intestinal and Vaginal Microbiota in Long-term Survivors of Gynecological Cancer
The study proposes the characterization of the intestinal and vaginal microbiota in long-term radiated cervical and endometrial cancer survivors to study the association with long-term radiotherapy side effects.
- Trial name
- NCT05360459
- Testing
- Exposure to radiotherapy
- Where
- Spain
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Maria Bailen Andrino
Cognitive Remediation, Neuropsychology
Longitudinal Neurocognitive, Psychosocial and Health-related Quality of Life Assessment in Advanced Cancer Survivors Treated With Immunotherapy and the Efficacy of Integrative Neurocognitive Remediation Therapy
Since 2010, the field of immunotherapy has grown substantially, leading to a growing population of long-term cancer survivors treated with immunotherapy.
- Conditions
- Cognitive Remediation, Neuropsychology, Quality of Life, Psycho-Oncology
- Trial name
- CognIT (NCT05667857)
- Testing
- Integrative neurocognitive remediation therapy
- Where
- 2 sites in Belgium
- Volunteers
- 100 people
- Sponsor
- Universitair Ziekenhuis Brussel
Hepatitis C Virus Infection
14 vs 24 Weeks HCV Treatment to Genotype 2/3 Patients With Rapid Virological Response
Patients with HCV genotype 2 or 3 infection who have a rapid virological response to treatment are randomised to either 14 or 24 weeks HCV treatment.
- Trial name
- NCT00308048
- Testing
- Pegylated Interferon alfa 2b and ribavirin
- Where
- Norway
- Volunteers
- 435 people
- Sponsor
- Ullevaal University Hospital
Family, Dementia
Evaluation of "My Tools 4 Care" for Family Caregivers of Persons With Dementia
With the number of Canadians with Alzheimer's disease and related dementias (ADRD) growing, supporting family care partners of persons with ADRD is critical.
- Trial name
- NCT02428387
- Testing
- My Tools 4 Care
- Where
- 2 sites in Canada
- Volunteers
- 199 people, healthy volunteers welcome
- Sponsor
- University of Alberta
Sarcoma
Assessing Health-related Quality of Life in Sarcoma Patients
Although the clinical effectiveness of sarcoma treatment has improved, long-lasting and cumulative treatment side-effects may often detract from the overall marginal advantage.
- Trial name
- NCT04071704
- Where
- 3 sites in Germany, Jordan
- Volunteers
- 654 people
- Sponsor
- The Netherlands Cancer Institute
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