Clinical trials: Health-related Quality of Life
Healthy, Psychological Well Being
Survey of Psychological Well-being of Health Care Workers in the Hospital Setting
The psychological well-being of healthcare workers in hospital settings is a topic of growing interest in the scientific literature, given the crucial importance of their role in ensuring high-quality care.
- Conditions
- Healthy, Psychological Well Being, Stress Response, Professional Quality of Life
- Trial name
- IN-VISIBLE (NCT06923436)
- Testing
- Psychological Assessment
- Volunteers
- 500 people
- Sponsor
- Fondazione Policlinico Universitario Agostino Gemelli IRCCS
Depression, Anxiety, Post Traumatic Stress Disorder
Effects of a Digital Diary on the Psychological Well-being of Former ICU Patients.
Previous research on the impact of a diary on mental symptoms of PICS, PICS-F, and quality of life in former ICU patients and their relatives has focused specifically on a paper diary.
- Conditions
- Depression, Anxiety, Post Traumatic Stress Disorder, Quality of Life
- Trial name
- DIPIC (NCT06237699)
- Testing
- Digital ICU diary
- Where
- 4 sites in Netherlands
- Volunteers
- 400 people
- Sponsor
- Erasmus Medical Center
Thyroid Diseases
Health-Related Quality of Life for Thyroid Patients
Background: Thyroid diseases are frequent. They include both metabolic changes and gland enlargement (goitre). Previous research and clinical suspicion indicate that the life quality of many patients is reduced despite successful…
- Trial name
- NCT00150033
- Where
- Denmark
- Volunteers
- 1,200 people
- Sponsor
- Odense University Hospital
HIV/AIDS and Infections, Patient Preference
Patient-Reported Outcomes HIV BItherapy
HIV Treatment simplification strategies that involve switching cART regimens from four or three antiretrovirals to two in virologically suppressed patients living with HIV are now available in order to reduce long-term toxicity…
- Trial name
- PROBI (NCT04788784)
- Where
- 3 sites in France
- Volunteers
- 250 people
- Sponsor
- University Paris 7 - Denis Diderot
Heart Failure
AI-Based Personalized Self-Management for Patients With Heart Failure
This study aims to evaluate the effectiveness of an AI-based personalized self-management intervention on self-care behaviors and health-related quality of life among patients with chronic heart failure.
- Trial name
- NCT07841665
- Testing
- Experimental: AI-Based Personalized Self-Management Intervention, Behavioral: AI-Based Personalized Self-Management Intervention
- Where
- 2 sites in Egypt
- Volunteers
- 150 people
- Sponsor
- Alexandria University
Health-Related Quality of Life, Physical Activity
Prosocial Behavior and Exercise Among Older Adults
The purpose of this study is to compare two exercise programs to determine how well they help older adults make exercise a regular habit after 9 months.
- Conditions
- Health-Related Quality of Life, Physical Activity, Physical Function
- Trial name
- NCT00747019
- Testing
- Prosocial Behavior Physical Activity (PBPA), Physical Exercise (PE)
- Where
- United States
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- National Institute on Aging (NIA)
Hepatitis C, Chronic, Genotype 1
Quality of Life During Treatment of Chronic Hepatitis C (P05278/MK-4031-336)
The primary objective of this study is to evaluate the impact of chronic hepatitis C (CHC), and the treatment thereof with peginterferon alpha-2b (PEG) and ribavirin (RBV) according to standard clinical practice, on the…
- Conditions
- Hepatitis C, Chronic, Genotype 1, HCV-1
- Trial name
- VIDA (NCT00863109)
- Testing
- Peginterferon alfa-2b (PEG), Ribavirin (RBV)
- Volunteers
- 133 people
- Sponsor
- Merck Sharp & Dohme LLC
Healthy
Probiotics and Health-related Quality of Life in Individuals With Seasonal Allergies
In this randomized, double-blind, placebo-controlled study, participants with seasonal allergies will receive a daily probiotic or placebo for 8 weeks.
- Trial name
- JEN (NCT02349711)
- Testing
- Probiotic mixture
- Where
- United States
- Volunteers
- 224 people, healthy volunteers welcome
- Sponsor
- University of Florida
Adolescent
Dietary Acid Load and Oral Health Quality in Adolescents
This study investigates the link between dietary acid load and oral health-related quality of life in 374 high school students (226 females, 148 males).
- Trial name
- NCT06803511
- Where
- Turkey (Türkiye)
- Volunteers
- 374 people, healthy volunteers welcome
- Sponsor
- Ankara Yildirim Beyazıt University
Depression, Post-Traumatic Stress Disorder
Improving Quality-of-life and Depressive Symptoms of Combat Veterans Via Internet-based Intervention
Background: Current military involvement in Afghanistan (Operation Enduring Freedom - OEF) and Iraq (Operation Iraqi Freedom - OIF) has created unforeseen burdens on the mental health and well-being of US service women and men.
- Conditions
- Depression, Post-Traumatic Stress Disorder, Functional Status
- Trial name
- NCT01231711
- Testing
- Vets Prevail
- Where
- United States
- Volunteers
- 50 people
- Sponsor
- Prevail Health Solutions, LLC
Hallux Valgus
Efficacy of Splinting, Exercise and Electrotherapy on Hallux Valgus
The aim of this study was to investigate the effects of splinting, exercise and electrotherapy on the hallux valgus (HV) angle, and foot-specific health-related quality of life.
- Trial name
- NCT04393545
- Testing
- hallux valgus night splint, exercise, Electrotherapy
- Volunteers
- 60 people
- Sponsor
- Ankara Yildirim Beyazıt University
Anemia, Anemia of Cancer
Darbepoetin Alfa and Anemia of Cancer
This phase 2, multicenter, randomized, open-label, comparative study was designed to determine the effect of darbepoetin alfa on hospital days, economic outcomes, and health related quality of life (HRQOL) in anemic patients with…
- Conditions
- Anemia, Anemia of Cancer, Cancer, Carcinoma
- Trial name
- NCT00989092
- Testing
- darbepoetin alfa
- Volunteers
- 287 people
- Sponsor
- Amgen
Trigger Finger
Function and Scar in Trigger Finger Release
Trigger finger is a common upper limb impairment associated with a significant decrease in quality of life, hand dexterity and strength as well as increased pain while complying daily activities of living.
- Trial name
- NCT05477290
- Testing
- Trigger Finger Release through Transverse Incision, Trigger Finger Release through Oblique Incision, Trigger Finger Release through Vertical Incision
- Where
- Canada
- Volunteers
- 75 people
- Sponsor
- McMaster University
Diabetes Mellitus Type 2
Hypoglycemia- and Weight-related Quality of Life in Patients With Diabetes Mellitus Type 2 on Sulfonylurea Derivatives.
1. A prospective, non-interventional study, 125 patients with Diabetes Mellitus Type2 will be enrolled, who, while on metformin, have a sub-optimal glycemic control and who thus will receive additional treatment with a…
- Trial name
- NCT01244646
- Where
- 22 sites in Netherlands
- Volunteers
- 48 people
- Sponsor
- AstraZeneca
Transfusion-dependent Beta-Thalassemia, Gene Therapy
Growth and Development-related Outcomes in Children With Transfusion-dependent Beta-thalassemia After Gene Therapy
The investigate will conduct a cohort study to compare the growth and development, metabolism, lifestyle behavior, and health-related quality of life among three groups: children with transfusion-dependent β-thalassemia (TDT) who…
- Trial name
- NCT05991336
- Testing
- Gene therapy
- Where
- China
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Institute of Hematology & Blood Diseases Hospital, China
Congenital Heart Disease
Exercise Training in Children With Congenital Heart Defect
The purpose of this study was to investigate the effects of exercise training on exercise capacity, physical activity (PA), health-related quality of life (HRQoL), and the psychosocial factors affecting PA in sedentary congenital…
- Trial name
- NCT00930800
- Testing
- Exercise
- Where
- Taiwan
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- National Taiwan University Hospital
Longevity, Women's Health
A Real-World Evidence Study Evaluating the Effects of the Human Optimization Project Protocol on Methylation Biomarkers and Health-Related Quality of Life in Women
This study looks at whether a daily dietary supplement called HOP Box can improve markers of biological aging and overall health in women.
- Trial name
- NCT07548645
- Testing
- Human Optimization Project
- Where
- United States
- Volunteers
- 35 people, healthy volunteers welcome
- Sponsor
- Human Optimization Project
Systemic Lupus Erythematosus, Quality of Life
Health-related Quality of Life Measure in Pediatric Lupus
To examine the psychometric properties of a brief quality of life (QOL) instrument for use in pediatric systemic lupus erythematosus (SLE).
- Trial name
- NCT00280137
- Where
- 11 sites in United States
- Volunteers
- 31 people
- Sponsor
- Rutgers, The State University of New Jersey
Quality of Life, PTSD
Improving Behavioral Health for Caregivers and Children After Pediatric Injury
Pediatric traumatic injury (PTI) is a public health priority, with more than 125,000 children experiencing injuries that require hospitalization each year.
- Conditions
- Quality of Life, PTSD, Depression Not Otherwise Specified, Child Externalizing Behavior
- Trial name
- NCT06856057
- Testing
- Caregivers' Aid to Accelerate Recovery after pediatric Emergencies (CAARE)
- Where
- 4 sites in United States
- Volunteers
- 348 people, healthy volunteers welcome
- Sponsor
- Medical University of South Carolina
Chronic Lymphocytic Leukemia
A Study to Assess Change in Functioning and Health Related Quality of Life in Adult Participants With Chronic Lymphocytic Leukemia (CLL) Receiving Oral Treatments in Routine Clinical Practice in Spain
Chronic lymphocytic leukemia (CLL) is the most common leukemia in the Western world. Since in most cases CLL remains an incurable disease, the goals of therapy are to improve quality of life and to prolong survival.
- Trial name
- PROVIDENCE (NCT06125795)
- Where
- 25 sites in Spain
- Volunteers
- 146 people
- Sponsor
- AbbVie