Clinical trials: Healthcare Associated Infection
Ventilator Associated Pneumonia, Multi-antibiotic Resistance
Ventilator Associated Pneumonia by Multi-Drug Resistant Organism
Ventilator-associated pneumonia (VAP) is an infection of the pulmonary parenchyma in patients exposed to invasive mechanical ventilation for at least 48 h and is part of ICU-acquired pneumonia.
- Trial name
- VAP-MDR (NCT05549427)
- Testing
- Ventilation
- Where
- Oman
- Volunteers
- 319 people
- Sponsor
- Sultan Qaboos University
Severe Pneumonia, Community-acquired Pneumonia
Efficacy of Intravenous Amboxol Hydrochloride as an Adjunct Therapy for Severe Pneumonia in Critically Ill Patients
Ambroxol is a mucolytic containing an active N-desmethyl metabolite of bromhexine. It is approved by both the U.S. FDA and EMA to be marketed under several formulations including oral, nasal, oro-mucosal, rectal and intravenous…
- Conditions
- Severe Pneumonia, Community-acquired Pneumonia, Hospital-acquired Pneumonia, Critical Illness
- Trial name
- NCT05663905
- Testing
- Ambroxol Hydrochloride, Standard Therapy
- Where
- Malaysia
- Volunteers
- 32 people
- Sponsor
- National University of Malaysia
Infection, Bacterial, Antibiotic Resistant Infection
Rapid Test for Detection of the Focus of Infection in Post Neurosurgical Patients.
Background: Due to anatomical restrictions, the inflammatory response to intra-cerebral bacterial infections exposes swollen brain tissues to pressure and ischemia, resulting in life-threatening damage.
- Conditions
- Infection, Bacterial, Antibiotic Resistant Infection, Diagnostic Self Evaluation, Meningitis, Bacterial
- Trial name
- NCT03252028
- Where
- 2 sites in Sweden
- Volunteers
- 150 people, healthy volunteers welcome
- Sponsor
- Fariba Nayeri
Ventilator-Associated Pneumonia, Mechanical Ventilation
Prevention of Ventilator-Associated Pneumonia by Automatic Control of the Tracheal Tube Cuff Pressure
Background: The aspiration of contaminated secretions pooled above the endotracheal tube cuff secondary to inadvertent falls of cuff pressure is the main pathogenic mechanism of ventilator-associated pneumonia (VAP).
- Trial name
- NCT00364299
- Testing
- Automatic control of tracheal tube cuff pressure
- Where
- Spain
- Volunteers
- 142 people
- Sponsor
- Hospital Clinic of Barcelona
VAP - Ventilator Associated Pneumonia
The Effectiveness of the Modified Bundle in the Prevention of VAP.
Ventilator-associated pneumonia (VAP) is an important cause of prolonged intensive care unit and hospital length of stay, healthcare costs and mortality in mechanically ventilated patients.
- Trial name
- VAP (NCT04038814)
- Testing
- Routine prevention of VAP, Modified prevention of VAP
- Where
- Poland
- Volunteers
- 386 people
- Sponsor
- Andrzej Frycz Modrzewski Krakow University
Pneumonia, Ventilator Associated, Closed System Suction Catheter
Time Interval for Changing Closed System Suction Catheters, Effect on Ventilator Associated Pneumonia
The purpose of this study was to compare the incidence of ventilator-associated pneumonia between two groups of patients randomised to have closed system suction catheter changes every 24 hours and patients having closed system…
- Trial name
- NCT00447109
- Testing
- Closed system suction
- Where
- Australia
- Volunteers
- 344 people, healthy volunteers welcome
- Sponsor
- Bayside Health
Gram-Positive Bacterial Infections, Cross Infection
Study Comparing Tigecycline to Imipenem/Cilastatin in Complicated Intra-Abdominal Infections in Hospitalized Subjects
Purpose: To provide a mechanism for the emergency use of tigecycline in the appropriate clinical situations.
- Trial name
- NCT00081744
- Testing
- Tigecycline
- Volunteers
- 850 people
- Sponsor
- Wyeth is now a wholly owned subsidiary of Pfizer
Pneumonia
Ceftobiprole in Hospital Acquired Pneumonia
The purpose of this study is to compare the clinical cure rate of ceftobiprole medocaril (the water-soluble prodrug [form] of ceftobiprole) referred to as ceftobiprole versus a comparator in the treatment of patients with…
- Trial name
- NCT00210964
- Testing
- linezolid plus ceftazidime
- Volunteers
- 781 people
- Sponsor
- Basilea Pharmaceutica
Coagulopathy, Nosocomial Pneumonia
Effect of Antioxidant Vitamins on Coagulopathy and Nosocomial Pneumonia After Severe Trauma
The purpose of this study is to determine the effect of antioxidant vitamins (vitamins C and E) on the development of coagulation derangements and nosocomial pneumonia after severe trauma in patients.
- Trial name
- NCT01897792
- Testing
- Vitamin C, Vitamin E, Saline (for Vitamin C)
- Where
- United States
- Volunteers
- 11 people
- Sponsor
- University of Alabama at Birmingham
Mechanical Ventilation Complication, Ventilator Associated Pneumonia
Semirecumbent Position by Mechanical Ventilation
It's based in an observational trial in mechanical ventilated patients. The investigators assess the head of bed elevation angle in the routine treatment of the unit.
- Conditions
- Mechanical Ventilation Complication, Ventilator Associated Pneumonia, Compliance, Treatment
- Trial name
- NCT04149665
- Testing
- simple blind observation
- Where
- Switzerland
- Volunteers
- 30 people
- Sponsor
- Bürgerspital Solothurn
Health Care Associated Infection
Health Care Associated Infection Surveillance in NICU
Healthcare - Associated Infection Surveillance In Neonatal Intensive Care Unit of Assiut University Children's Hospital.The objective of study is to determine the incidence, infection sites, causative organisms and risk factors…
- Trial name
- NCT03254316
- Where
- Egypt
- Volunteers
- 100 people
- Sponsor
- Gehad Salah El-Den Mahmoud Mohammad
Pneumonia
Physiotherapy on Pneumonia in Childrens
The children's susceptibility to respiratory problems is due to their anatomical and physiological characteristics; therefore, children with more severe clinical conditions may undergo invasive mechanical ventilation (IMV).
- Trial name
- VAP (NCT03343717)
- Testing
- Rehabilitation, Chest physical therapy
- Where
- Brazil
- Volunteers
- 40 people
- Sponsor
- Universidade Metodista de Piracicaba
Ventilator Associated Pneumonia
Study of Knowledge Translation of Clinical Practice Guidelines for Ventilator Associated Pneumonia
The purpose of this prospective, multicentre, time-series study is to develop, implement, refine, and evaluate a sustainable behaviour change strategy in the intensive care unit (ICU).
- Trial name
- ABATEVAP (NCT00434460)
- Testing
- Education
- Where
- 11 sites in United States, Canada
- Volunteers
- 1,320 people
- Sponsor
- Canadian Critical Care Trials Group
MRSA, VRE
Benefits of Universal Glove and Gowning
This study will test if doctors, nurses and other people who take care of patients in hospitals wearing gloves and gown for all contact with patients in an intensive care unit (ICU) will: Decrease the chance of patients getting…
- Trial name
- BUGG (NCT01318213)
- Where
- United States
- Volunteers
- 19,856 people
- Sponsor
- University of Maryland, Baltimore
Ventilator Associated Pneumonia, Covid19
Presepsin Biomarker for Ventilator-associated Pneumonia Diagnosis in COVID-19 Patients
This study is observational and double blind. It evaluates the validity of presepsin (a serum biomarker of bacterial infections) as early biomarker of Ventilator Associated Pneumonia.
- Trial name
- NCT04840940
- Where
- Italy
- Volunteers
- 50 people
- Sponsor
- San Luigi Gonzaga Hospital
Health Care Utilization, Health Care Associated Infection
COVID19 Vaccination: Clinical, Laboratory and Cellular Monitoring
Primary objective: 1. Monitor adverse events (Adverse Event Following Immunization - AEFI) in vaccinated subjects and analyze the associations with: (a) demographic variables and anthropometric parameters (sex, age, BMI, etc.)…
- Trial name
- SAPIENZAVAX (NCT04844632)
- Testing
- Vaccine anti-Covid19
- Where
- Italy
- Volunteers
- 5,000 people, healthy volunteers welcome
- Sponsor
- University of Roma La Sapienza
Ventilator-Associated Pneumonia, Severe Pneumonia
Fiberoptic Bronchoscopy in Severe Ventilator-associated Pneumonia
This randomized controlled trial evaluated the clinical effect of fiberoptic bronchoscopy in the management of adult patients with severe ventilator-associated pneumonia (VAP).
- Conditions
- Ventilator-Associated Pneumonia, Severe Pneumonia, Critical Illness
- Trial name
- NCT07149909
- Testing
- Other (Conventional Therapy), Fiberoptic Bronchoscopy
- Where
- Egypt
- Volunteers
- 100 people
- Sponsor
- Benha University