Clinical trials: Healthy, no Evidence of Disease
Conditions Influencing Health Status, Healthy
Comparing the Reliability of Expressed Prostatic Secretion (EPS) and Post Massage Urine (PMU) for the Prediction of Prostate Cancer Biopsy Outcome
This randomized pilot phase I trial studies the best way, either expressed prostatic secretion (EPS) or post massage urine (PMU) biomarkers, of predicting biopsy results in patients undergoing prostate biopsy.
- Conditions
- Conditions Influencing Health Status, Healthy, Prostate Cancer
- Trial name
- NCT01441687
- Testing
- laboratory biomarker analysis, transrectal prostate biopsy
- Where
- 5 sites in United States
- Volunteers
- 243 people, healthy volunteers welcome
- Sponsor
- City of Hope Medical Center
Healthy
Lorazepam, Diphenhydramine Hydrochloride, and Haloperidol Gel in Healthy Volunteers
RATIONALE: Lorazepam, diphenhydramine hydrochloride, and haloperidol gel, when absorbed into the skin, may be an effective treatment for nausea and vomiting.PURPOSE: This clinical trial studies lorazepam, diphenhydramine…
- Trial name
- NCT01204255
- Testing
- lorazepam, diphenhydramine hydrochloride, haloperidol
- Where
- United States
- Volunteers
- 11 people, healthy volunteers welcome
- Sponsor
- Virginia Commonwealth University
Multiple Sclerosis
Modeling and Treating the Pathophysiology of Demyelination in Multiple Sclerosis
The investigators principal hypothesis is that INO and optic neuritis are objective, quantitative, and reproducible models for corroborating the hypothesis that changes in core body temperature are associated with the reversible…
- Trial name
- NCT00854750
- Testing
- ACTHAR
- Where
- United States
- Volunteers
- 1 people, healthy volunteers welcome
- Sponsor
- Elliot Frohman
Healthy, no Evidence of Disease
Dose-Finding of Retinoid 9cUAB30 in Healthy Volunteers
This randomized phase I trial studies the side effects and the best dose of retinoid 9cUAB30 in healthy volunteers. Chemoprevention is the use of certain drugs to keep cancer from forming.
- Trial name
- NCT01336387
- Testing
- retinoid 9cUAB30, pharmacological study, laboratory biomarker analysis
- Where
- United States
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- National Cancer Institute (NCI)
Healthy, no Evidence of Disease, Obesity
Time Restricted Diet in Obese or Overweight Pre or Postmenopausal Participants
The purpose of this study is to study the relationships between obesity, hormones and menopausal status, and breast cancer. The researchers would like to study whether a type of nutritional intervention, called a time-restricted…
- Trial name
- NCT02154984
- Testing
- behavioral dietary intervention, telephone-based intervention, laboratory biomarker analysis
- Where
- United States
- Volunteers
- 45 people, healthy volunteers welcome
- Sponsor
- Northwestern University
Healthy, no Evidence of Disease, Lobular Breast Carcinoma in Situ
Letrozole in Preventing Breast Cancer in Healthy Postmenopausal Women at High Risk for Breast Cancer
This randomized phase I trial studies the side effects and the best dose of letrozole in preventing breast cancer in healthy postmenopausal women at high risk for breast cancer.
- Trial name
- NCT01077453
- Testing
- letrozole, quality-of-life assessment, laboratory biomarker analysis
- Where
- 3 sites in United States
- Volunteers
- 112 people, healthy volunteers welcome
- Sponsor
- National Cancer Institute (NCI)
Healthy, no Evidence of Disease
Se-Methyl-Seleno-L- Cysteine (MSC) in Treating Healthy Patients
This randomized phase I trial is studying the side effects and best dose of Se-methyl-seleno-L-cysteine in healthy adult men. Studying samples of blood, urine, and toenail clippings in the laboratory from healthy men receiving…
- Trial name
- NCT00489372
- Testing
- Se-methyl-seleno-L-cysteine, pharmacological study, laboratory biomarker analysis
- Where
- 2 sites in United States
- Volunteers
- 36 people
- Sponsor
- National Cancer Institute (NCI)
Healthy Stem Cell Donor, No Evidence of Disease
Collection of Bone Marrow From Donors Treated With or Without Filgrastim
This randomized clinical trial is studying the side effects of collection of bone marrow from donors treated with or without filgrastim.
- Trial name
- NCT01149096
- Testing
- Bone Marrow Donation, Filgrastim, Laboratory Biomarker Analysis
- Where
- 22 sites in United States
- Volunteers
- 13 people, healthy volunteers welcome
- Sponsor
- Children's Oncology Group
Healthy, no Evidence of Disease
Web-Based Tailored Educational Program in Improving Nurse Communication With Patients About Clinical Trials
This pilot, randomized clinical trial studies a web-based tailored educational program in improving nurse communication with patients about clinical trial treatment options.
- Trial name
- NCT02129517
- Testing
- IMPACT intervention, Online education materials, survey administration
- Where
- United States
- Volunteers
- 1,262 people, healthy volunteers welcome
- Sponsor
- Case Comprehensive Cancer Center
Healthy, No Evidence of Disease
Effects of Garlic Supplements on Opioids in Healthy Volunteers
RATIONALE: Garlic supplements may alter the pharmacokinetics of oxycodone, thereby affecting its effectiveness as an opioid analgesic for the relief of moderate or severe pain.
- Trial name
- NCT00499460
- Testing
- garlic powder tablets, oxycodone
- Where
- United States
- Volunteers
- 15 people, healthy volunteers welcome
- Sponsor
- Fred Hutchinson Cancer Center
No Evidence of Disease
Celecoxib in Decreasing the Damaging Effects of Sunburn in Healthy Volunteers
This clinical trial studies celecoxib in decreasing the damaging effects of sunburn in healthy volunteers. Celecoxib may reduce skin damage by blocking enzymes associated with sunburn in healthy volunteers.
- Trial name
- NCT02090933
- Testing
- Celecoxib, Laboratory Biomarker Analysis, UV Light Therapy
- Where
- United States
- Volunteers
- 25 people, healthy volunteers welcome
- Sponsor
- National Cancer Institute (NCI)
Healthy, no Evidence of Disease
Bowman-Birk Inhibitor Concentrate in Healthy Men
This randomized phase I trial is studying the side effects and best dose of Bowman-Birk inhibitor concentrate in healthy men. Chemoprevention is the use of certain drugs to keep cancer from forming.
- Trial name
- NCT00679094
- Testing
- Bowman-Birk inhibitor concentrate, pharmacological study, laboratory biomarker analysis
- Where
- United States
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- National Cancer Institute (NCI)
Colorectal Cancer, Healthy, no Evidence of Disease
Genetic Epidemiology Risk Assessment Program or Usual Care in Colorectal Cancer Screening for Healthy Participants
RATIONALE: The Genetic Epidemiology and Risk Assessment program may be more effective than usual care in increasing the number of healthy participants who regularly receive screening for colorectal cancer.
- Trial name
- NCT00478309
- Testing
- counseling intervention, educational intervention
- Where
- United States
- Volunteers
- 697 people, healthy volunteers welcome
- Sponsor
- Fox Chase Cancer Center
Healthy, no Evidence of Disease, Stage II Breast Cancer
Light-Scattering Spectroscopy for Detection of Breast Cancer
This pilot clinical trial studies light-scattering spectroscopy in finding disease in patients with stage II-III breast cancer. Diagnostic procedures, such as light-scattering spectroscopy, may help find and diagnose breast cancer
- Conditions
- Healthy, no Evidence of Disease, Stage II Breast Cancer, Stage IIIA Breast Cancer, Stage IIIB Breast Cancer
- Trial name
- NCT01755208
- Testing
- light-scattering spectroscopy
- Where
- United States
- Volunteers
- 110 people, healthy volunteers welcome
- Sponsor
- University of Southern California
No Evidence of Disease
Celecoxib in Preventing the Damaging Effects of Sunburn in Healthy Volunteers
This randomized clinical trial studies if celecoxib will prevent the damaging effects of sunburn in healthy volunteers. Exposure to ultraviolet light can induce erythema, sunburn or skin redness caused by inflammation.
- Trial name
- NCT02099136
- Testing
- UV Light Therapy, Celecoxib, Biopsy
- Where
- United States
- Volunteers
- 45 people, healthy volunteers welcome
- Sponsor
- National Cancer Institute (NCI)
Colorectal Cancer, Healthy, no Evidence of Disease
Narrative or Fact-Based Videos in Increasing Colorectal Cancer Screenings in African American Communities
This randomized clinical trial studies narrative or fact-based videos in increasing colorectal cancer screenings in African American communities.
- Trial name
- NCT02100254
- Testing
- behavioral intervention
- Where
- 2 sites in United States
- Volunteers
- 1,310 people, healthy volunteers welcome
- Sponsor
- Roswell Park Cancer Institute
Hepatocellular Carcinoma, Cholangiocarcinoma
Hepatobiliary Tumors Tissue Samples Acquisition
Hepatobiliary tumors have a poor prognosis and high individual heterogeneity, so it is of great significance to find important prognostic markers and then screen out specific subgroups of people; meanwhile, chronic hepatitis…
- Conditions
- Hepatocellular Carcinoma, Cholangiocarcinoma, Gallbladder Cancer, Biliary Tract Cancer
- Trial name
- NCT04445532
- Testing
- Gene expression analysis, Genomic analysis, Protein expression analysis
- Where
- China
- Volunteers
- 450 people, healthy volunteers welcome
- Sponsor
- Peking Union Medical College Hospital
No Evidence of Disease, Prostate Carcinoma
Se-Methyl-Seleno-L-Cysteine or Selenomethionine in Preventing Prostate Cancer in Healthy Participants
This randomized phase I trial studies the side effects and the best dose of Se-methyl-seleno-L-cysteine or selenomethionine in preventing prostate cancer in healthy participants.
- Trial name
- NCT01497431
- Testing
- Selenium, Laboratory Biomarker Analysis, Pharmacological Study
- Where
- 3 sites in United States
- Volunteers
- 66 people, healthy volunteers welcome
- Sponsor
- National Cancer Institute (NCI)
Healthy, no Evidence of Disease
Effect of Weight Loss on Breast Density Using Digital Mammography and MRI in Women Who Are At Increased Risk For Breast Cancer
Diagnostic procedures, such as digital mammography and MRI, may help measure how weight loss affects breast density in women who are at increased risk for breast cancer.
- Trial name
- NCT01259076
- Testing
- magnetic resonance imaging, digital mammography, conventional surgery
- Where
- United States
- Volunteers
- 43 people, healthy volunteers welcome
- Sponsor
- Northwestern University
Healthy, no Evidence of Disease
A Nutritional Supplement Capsule Containing Curcumin, Green Tea Extract, Polygonum Cuspidatum Extract, and Soybean Extract in Healthy Participants
RATIONALE: Studying samples of blood and urine from healthy participants receiving antioxidant nutritional supplements may help doctors identify changes in biomarkers related to oxidative stress.
- Trial name
- NCT00768118
- Testing
- curcumin/green tea extract/Polygonum cuspidatum extract/soybean extract capsule, electrophoretic mobility shift assay, laboratory biomarker analysis
- Where
- United States
- Volunteers
- 11 people, healthy volunteers welcome
- Sponsor
- Barbara Ann Karmanos Cancer Institute