Clinical trials: Healthy
Healthy
Implant Pharmacokinetic and Pharmacodynamic Study
This is a single center, pharmacokinetic and pharmacodynamic study in healthy volunteers. Twenty four subjects will be enrolled in the study and will be assigned to receive either a 16 mg afamelanotide bioresorbable implant from…
- Trial name
- NCT03634137
- Testing
- Afamelanotide Group 1, Afamelanotide Group 2
- Where
- United States
- Volunteers
- 24 people, healthy volunteers welcome
- Sponsor
- Clinuvel Pharmaceuticals Limited
Healthy
Study to Assess the Influence of Three Different α-antagonists and Placebo on the Extent of Weekly Phenylephrine-induced Mydriasis at Three Different Concentrations of Phenylephrine in Healthy Male Volunteers
The study was aimed to evaluate the pharmacological effect of different α-antagonists on phenylephrine induced pupil size in healthy male volunteers as pharmacological basis for Intraoperative floppy iris syndrome (IFIS)
- Trial name
- NCT02266537
- Testing
- Tamsulosin, Alfuzosin, Doxazosin
- Volunteers
- 97 people, healthy volunteers welcome
- Sponsor
- Boehringer Ingelheim
Addiction
A Study to Assess 18-Methoxycoronaridine (18-MC HCl) in Healthy Volunteers
The primary objective of this study is to assess the safety and tolerability of a single day dosing and a separate multiple day dosing of 18-MC HCl administered orally, each part of the study having a different set of healthy…
- Trial name
- NCT04292197
- Testing
- 18-MC Compound
- Where
- Australia
- Volunteers
- 108 people, healthy volunteers welcome
- Sponsor
- Definium Therapeutics US, Inc.
Neuromuscular Performance, Balance and Function
Immediate and Delayed Effects of Kinesio Taping on the Neuromuscular Performance
The purpose of this study is analyze the immediate and late effects of the application of KT in neuromuscular performance of the quadriceps in postural balance and function of the lower limb of healthy subjects.
- Trial name
- IDEKTNP (NCT02431910)
- Testing
- Functional elastic tape
- Where
- Brazil
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Universidade Federal do Rio Grande do Norte
Amyotrophic Lateral Sclerosis (ALS)
A First in Human Study of ORT247 in Healthy Volunteers
This is a single center, double-blinded, randomized, placebo controlled single ascending dose clinical study, with the primary purpose of evaluating the safety, tolerability, pharmacokinetics (PK), and immunohistochemistry of…
- Trial name
- NCT06769620
- Testing
- ORT247
- Where
- United States
- Volunteers
- 44 people, healthy volunteers welcome
- Sponsor
- Orthogonal Neuroscience Inc.
Parkinson Disease
Study To Assess the Safety and Tolerability of PBF-509 in Male Healthy Volunteers
No clinical trials with PBF-509 in humans have been performed to date. Only preclinical studies have been done to assess the pharmacology and pharmacokinetics, the safety and the toxicological profile of the PBF-509.
- Trial name
- NCT01691924
- Testing
- PBF-509
- Where
- 2 sites in Spain
- Volunteers
- 56 people, healthy volunteers welcome
- Sponsor
- Fundació Institut de Recerca de l'Hospital de la Santa Creu i Sant Pau
Osteoporosis
Effects of Proteins Fraction Derived From Milk on Osteoporosis Prevention
Osteoporosis is defined as a systemic skeletal disease characterised by low bone mass and microarchitectural deterioration of bone tissue, with a consequent increase in bone fragility and susceptibility to fracture.
- Trial name
- NCT01478724
- Testing
- Milk proteins fraction
- Where
- France
- Volunteers
- 291 people, healthy volunteers welcome
- Sponsor
- Soredab
Hypertension
Bioequivalence Study in Healthy Subjects
This study is designed as a Phase-I, 2-period, cross-over, randomised, open-label, single centre study to determine bioequivalence of a single 32 mg dose of the proposed commercial oral suspension of candesartan cilexetil (1…
- Trial name
- NCT00844324
- Testing
- Candesartan cilexetil
- Where
- United Kingdom
- Volunteers
- 36 people, healthy volunteers welcome
- Sponsor
- AstraZeneca
Lactation Disorder - Postpartum Condition or Complication, Nutrition, Healthy
Use of Ritual Epost Postnatal Multivitamins During the Postpartum Period
Multivitamin/multimineral supplements (MVI) provide important nutrition supplement to the diet of pregnant women to cover potential deficiencies and optimize nutrition status of both mom and baby, especially when the diet is…
- Trial name
- NCT05736562
- Testing
- Ritual Epre Multimineral-Vitamin Supplement
- Where
- 2 sites in United States
- Volunteers
- 71 people, healthy volunteers welcome
- Sponsor
- City University of New York
Diet, Healthy
Chicory Fiber Effect on Satiety and GI Tolerance
The investigators are comparing 2 fiber treatments to a fiber free treatment for acute satiety and GI response.
- Trial name
- NCT04067362
- Testing
- food containing dietary fiber
- Where
- United States
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- University of Minnesota
Healthy Adult Subjects
A Food Effect Study of SHR1459 on Healthy Chinese Adult Subjects
The primary objective of the study is to evaluate the effect of high-fat diet on pharmacokinetics of healthy Chinese adult subjects after oral administration of SHR1459 tablets.
- Trial name
- NCT04291846
- Testing
- SHR1459 fasted in P1, high-fat diet in P2, SHR1459 high-fat diet in P1, fasted in P2
- Where
- China
- Volunteers
- 28 people, healthy volunteers welcome
- Sponsor
- Jiangsu HengRui Medicine Co., Ltd.
Healthy
Fasting Study of Paroxetine Hydrochloride Controlled-Release Tablets 25 mg to Paxil CR™ Tablets 25 mg
The objective of this study was to investigate the bioequivalence of Mylan's paroxetine hydrochloride controlled-release 25 mg tablets to GSK's Paxil CR™ 25 mg tablets following a single, oral 25 mg (1 x 25 mg) dose administered…
- Trial name
- NCT00648427
- Testing
- Paroxetine Hydrochloride Controlled-Release Tablets 25 mg, Paxil CR™ Tablets 25 mg
- Where
- United States
- Volunteers
- 75 people, healthy volunteers welcome
- Sponsor
- Mylan Pharmaceuticals Inc
Ascending Single Dose Study
Safety, Tolerability and Pharmacokinetics of TAK-438 in Healthy Male Participants
The primary purpose of this study was to evaluate the single dose safety and pharmacokinetics of TAK-438 in healthy Japanese men.
- Trial name
- NCT02123927
- Testing
- TAK-438
- Volunteers
- 108 people, healthy volunteers welcome
- Sponsor
- Takeda
Colorectal Cancer, Type2 Diabetes
Effect of Plant and Animal Proteins on Biomarkers of Colorectal Cancer and Type 2 Diabetes in Healthy Adults (ScenoProt)
The aim of this study is to investigate the effects of dietary plant and animal proteins on gut metabolism and markers for colorectal cancer as well as blood protein metabolites and markers for type 2 diabetes in healthy adults.
- Trial name
- ScenoProt (NCT03206827)
- Testing
- 70% animal, 30% plant proteins in diet, 50% animal, 50% plant proteins in diet, 30% animal, 70% plant proteins in diet
- Volunteers
- 147 people, healthy volunteers welcome
- Sponsor
- University of Helsinki
Effect of Drugs, Safety Issues
Pharmacokinetic Study of Lansoprazole Capsules in Healthy Chinese Volunteer
The objective of this study was to compare pharmacokinetic of Lansoprazole Capsules 30 mg with Lansoprazole Capsules of Takeda 30 mg in healthy adult human subjects.
- Trial name
- NCT03488173
- Testing
- Lansoprazole capsules
- Where
- China
- Volunteers
- 42 people, healthy volunteers welcome
- Sponsor
- First Affiliated Hospital of Zhejiang University
Healthy Volunteer, Female
Physiological and Psychological Profiles
The participation of women in high-impact sports such as rugby and basketball has been steadily increasing in Saudi Arabia. These sports are known for their physical demands and competitive nature, which have heightened the…
- Trial name
- NCT07026383
- Testing
- performance test
- Where
- Saudi Arabia
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Princess Nourah Bint Abdulrahman University
Endotoxemia, Inflammation
Short-Chain Fatty Acids in Lypopolysaccharide-Induced Inflammation and Executive Function
Short-chain fatty acids (SCFAs) are substances produced by gut bacteria when they ferment dietary fiber. They can act as signals between the gut and the brain and may help regulate the body's immune and stress responses.
- Conditions
- Endotoxemia, Inflammation, Executive Function (Cognition)
- Trial name
- NCT07713641
- Testing
- Short-Chain Fatty Acid Colon-Delivery Capsules, Lipopolysaccharide (LPS)
- Where
- Belgium
- Volunteers
- 56 people, healthy volunteers welcome
- Sponsor
- Universitaire Ziekenhuizen KU Leuven
Healthy Aging
Effect of a Two-month Carbohydrate-restricted Diet on Energy Metabolism in a Seniors' Residence
The present study will assess the effects on glucose, ketones and other blood biomarkers fuels, cognition, quality of life, physical activity and well-being of a reduced carbohydrate menu (R-CHO) for 2 months in a population…
- Trial name
- SAGE (NCT06022094)
- Testing
- 2 months of reduced carb menus
- Where
- Canada
- Volunteers
- 29 people, healthy volunteers welcome
- Sponsor
- Université de Sherbrooke
Healthy
HeaLED: Pilot Study of Skin Healing Under LED Exposure
The aim of this study is to assess cutaneous healing process under LED exposition on 10 healthy subjects pre-treated with fractional CO2 laser on mini-zones on forearms.
- Trial name
- HeaLed (NCT02677194)
- Testing
- LED, Control device
- Volunteers
- 10 people, healthy volunteers welcome
- Sponsor
- Centre Hospitalier Universitaire de Nice
Healthy
Study Evaluating LXR-623 in Healthy Subjects
To evaluate the safety and tolerability of a single dose of LXR-623 in healthy subjects.
- Trial name
- NCT00366522
- Testing
- LXR-623
- Where
- United States
- Volunteers
- healthy volunteers welcome
- Sponsor
- Wyeth is now a wholly owned subsidiary of Pfizer
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