Clinical trials: Healthy Adult
Hepatic Impairment, Healthy Adult Participants
A Study to Investigate the Safety, Tolerability, and Pharmacokinetics of Sonrotoclax in Participants With Severe Hepatic Impairment
The goal of this study is to understand how the body processes sonrotoclax in adults with serious liver problems compared to adults with normal liver function.
- Trial name
- NCT07855991
- Testing
- Sonrotoclax
- Volunteers
- 12 people, healthy volunteers welcome
- Sponsor
- BeOne Medicines
Gut Health, Gastrointestinal Symptoms
IgG Binding Protein LT in Support of a Healthy Gut on the Go
PS52 is a randomized, double-blind, placebo-controlled, fully decentralized study sponsored by Bactolife A/S and conducted by People Science, Inc.
- Conditions
- Gut Health, Gastrointestinal Symptoms, Safety in Healthy Adults
- Trial name
- NCT07873957
- Testing
- IgG Binding Protein LT
- Where
- United States
- Volunteers
- 800 people, healthy volunteers welcome
- Sponsor
- Bactolife A/S
Healthy, Parkinson Disease
Motion Capture in Box and Bloks Test
This study aims not only to develop a standardized protocol for performing the targeted BBT but also to assess synchronized parameters: kinematic (using IMUs) and electrophysiological (EMG) data.
- Conditions
- Healthy, Parkinson Disease, Stroke, Upper Extremity Paresis
- Trial name
- BBT_MOCAP (NCT07883174)
- Testing
- Inertial Measurement Unit and Box and Block test
- Where
- Italy
- Volunteers
- 105 people, healthy volunteers welcome
- Sponsor
- IRCCS San Raffaele Roma
Gingivitis, Healthy Adult
Comparative Evaluation of the Anti-Plaque and Anti-Gingivitis Effects of Nanobiofusion Gingival Gel (NBF), Placebo Gel, and Commercial Toothpaste
The goal of this clinical trial is to learn if Nanibiofusion Gingival Gel (NBF) is able to reduce dental plaque and gum inflammation in adults.
- Trial name
- NCT07850232
- Testing
- Nano Bio-Fusion (NBF) Gingival Gel, Commercial fluoride toothpaste
- Where
- Jordan
- Volunteers
- 45 people, healthy volunteers welcome
- Sponsor
- King Abdullah University Hospital
NAD+ Metabolism, Pharmacokinetics
Effects of Trigonelline Monohydrate on NAD+ Metabolism, Pharmacokinetics, Safety, and Tolerability in Healthy Adults
This Phase 1 study is designed to evaluate the pharmacokinetic, pharmacodynamic, bioavailability, safety, and tolerability effects of trigonelline monohydrate in generally healthy adults aged 40 to 70 years.
- Conditions
- NAD+ Metabolism, Pharmacokinetics, Bioavailability, Healthy Adults
- Trial name
- NCT07880925
- Testing
- Nicotinamide Mononucleotide (NMN), Trigonelline Monohydrate
- Where
- Canada
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- dsm-firmenich Switzerland AG
Healthy Adult Participants
A Multiple-dose Study Investigating the Drug-drug Interaction Potential and QTc Effects of Fosmanogepix in Healthy Adult Subjects
This is a Phase 1, fixed-sequence, multiple-dose study in approximately 42 healthy adult participants. The study will be conducted in two parts.
- Trial name
- NCT07881224
- Testing
- Fosmanogepix, The medicine cocktail (caffeine, bupropion, flurbiprofen, omeprazole, dextromethorphan and midazolam), Probe substrates (repaglinide, rosuvastatin, and digoxin)
- Where
- Netherlands
- Volunteers
- 42 people, healthy volunteers welcome
- Sponsor
- Basilea Pharmaceutica
Healthy Volunteer, Magnetic Resonance Imaging
Study of New Magnetic Resonance Imaging Methods of the Brain
The purpose of this investigation is to develop improved magnetic resonance imaging (MRI) techniques and hardware for studying brain function.
- Conditions
- Healthy Volunteer, Magnetic Resonance Imaging, Healthy, fMRI
- Trial name
- NCT00004577
- Where
- United States
- Volunteers
- 1,100 people, healthy volunteers welcome
- Sponsor
- National Institute of Neurological Disorders and Stroke (NINDS)
Healthy Young Adults, Healthy Adult Participants
Foam Rolling and Blood Pressure
Foam rolling (FR) has emerged as a widely adopted modality among rehabilitation practitioners and physically active populations.
- Conditions
- Healthy Young Adults, Healthy Adult Participants, Healthy Participants, Normotensive
- Trial name
- NCT07520474
- Testing
- Foam Rolling Intervention (FR)
- Where
- Italy
- Volunteers
- 29 people, healthy volunteers welcome
- Sponsor
- University of Palermo
Muscle Tone, Healthy Adult
Foam Roller Compared to Massage on Reducing Calf Muscle Tone in Healthy Subjects
Objective: This study aims to compare the effects of two techniques-foam rolling (FR) and therapeutic massage-on reducing the muscle tone in the calf muscles (gastrocnemius and soleus) of healthy individuals.
- Trial name
- FRTONE (NCT07564206)
- Testing
- Foam roller, Massage
- Where
- Spain
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- Universidad Europea de Madrid
Skin Ageing, Healthy Ageing
Effects of a Multi-Targeted Oral Supplement on Skin, Hair, Sleep, Energy, Cognition, Libido and Epigenetic Biological Clock Age
This study evaluated the effects of a daily oral supplement regimen (Advanced ID Brain, Heart and Eye Omega Gel Capsules taken with Advanced ID Longevity and Collagen Complex Powder) on measures of skin condition, hair, sleep…
- Conditions
- Skin Ageing, Healthy Ageing, Effect of Oral Nutritional Supplementation on Skin, Hair, Sleep, Energy, Cognition and Sexual Wellbeing in Healthy Adults, Longevity
- Trial name
- IDF-AID-1 (NCT07827651)
- Testing
- Advanced ID
- Where
- United Kingdom
- Volunteers
- 64 people, healthy volunteers welcome
- Sponsor
- IDI Skincare Limited
Healthy Adult
AdHuman - Impact of Food Additives in Humans
Food additives, in particular hydrocolloids (thickening, gelling and stabilising agents), are widely used in the food supply. Concerns about carrageenan have led the food industry to replace it with alternative hydrocolloids, yet…
- Trial name
- AdHuman (NCT07879079)
- Testing
- Carrageenan baked in bread, Xanthan and guar-gum baked in bread, Gellan baked in bread
- Where
- Norway
- Volunteers
- 160 people, healthy volunteers welcome
- Sponsor
- Siv K Bohn
Healthy Adult Subjects
Mass Balance Study of [14C]DA-302168S in Healthy Chinese Adult Male Participants
In this study, a single dose of [14C] radiolabelled DA-302168S will be administered orally. The main purpose of this study is to find out how much of DA-302168S and its metabolites pass from blood into urine and feces, and…
- Trial name
- NCT07857265
- Testing
- [14C] DA-302168S
- Volunteers
- 10 people, healthy volunteers welcome
- Sponsor
- Chendu DIAO Pharmaceutical Group CO., LTD.
Healthy Adult Participants
The Effect of A Slow-Paced Breathing Intervention on Heart Rate Variability, Stress, and Dysfunctional Breathing Patterns in Healthy Young Adults
The primary aim of this study is to evaluate the effects of a controlled breathing exercises-on autonomic nervous system functions (HRV) and perceived stress levels in healthy young adults with dysfunctional breathing patterns.
- Trial name
- SPB-HRV-RCT (NCT07874750)
- Testing
- slow-paced breathing
- Where
- Turkey (Türkiye)
- Volunteers
- 70 people, healthy volunteers welcome
- Sponsor
- Bahçeşehir University
Muscle Recovery, Oxidative Stress
Development of a Coffee Pulp Infusion as a Strategy for Recovery After Moderate Physical Exercise in a Healthy Population.
The goal of this clinical trial is to learn if a coffee pulp infusion works to improve muscle recovery after moderate physical exercise in a healthy adult population.
- Conditions
- Muscle Recovery, Oxidative Stress, Inflamation, Muscle Damage
- Trial name
- COPULP-REC (NCT07875699)
- Testing
- Two 250 mL infusions per day (one in the morning and one at night) for 45 consecutive days.
- Where
- Spain
- Volunteers
- 138 people, healthy volunteers welcome
- Sponsor
- David Ramiro Cortijo
Healthy Adult Participants
Safety and Efficacy of a Prebiotic Blend in Healthy Humans
The GRASP Trial is a 30-day, randomized, double-blind, placebo-controlled study (Protocol No.: GW-2025-02) designed to evaluate the safety and tolerability of a novel multi-fiber prebiotic blend in healthy adult volunteers (age…
- Trial name
- GRASP (NCT07514741)
- Testing
- Fiber Blend 1 (Low Dose), Fiber Blend 2 (High Dose)
- Where
- United States
- Volunteers
- 87 people, healthy volunteers welcome
- Sponsor
- LOAM Science
Healthy Young Adults
Exploring Wellbeing Outcomes in Adolescents Using Bifidobacterium Longum, 1714™
The purpose of this study is to evaluate changes in self-reported wellbeing outcomes in adolescents. Bifidobacterium longum, 1714™ has previously been associated with beneficial effects on stress-related outcomes, sleep quality…
- Trial name
- NCT07752342
- Testing
- Bifidobacterium longum, 1714™
- Where
- United Kingdom
- Volunteers
- 150 people, healthy volunteers welcome
- Sponsor
- Novonesis
Healthy Volunteer, Healthy Adult Participants
A Study to Assess the Bioequivalence of Efgartigimod PH20 SC Between Autoinjector and Prefilled Syringe in Healthy Adult Participants
The aim of this study is to compare the amount of efgartigimod in the blood over time after it is injected via Prefilled syringe (PFS) and Autoinjector (AI). The study will comprise 2 study periods of 3 weeks each.
- Trial name
- NCT07782775
- Testing
- Efgartigimod PH20 SC via PFS, Efgartigimod PH20 SC via AI
- Where
- Canada
- Volunteers
- 32 people, healthy volunteers welcome
- Sponsor
- argenx
Healthy Adult
Data-driven Rural Interventions for Vitality and Endurance Pilot Study
The study aims to explore whether data driven, personalized wellness interventions-based on integrated genomic, clinical, behavioral, and functional data- are feasible in a rural facing setting and can produce measurable…
- Trial name
- DRIVE (NCT07872995)
- Testing
- Data-driven lifestyle coaching
- Where
- United States
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- McLaughlin Research Institute for Biomedical Sciences, Inc.
Spinal Cord Injury (=3 Years), Traumatic Brain Injury (TBI) Patients
Evaluation of a Voice-Activated Call Light System for Clients With Limited Upper-Extremity Mobility
The goal of this study is to evaluate whether a voice-activated call light system enables people in a rehabilitation facility who have limited use of their arms and hands to call for help more independently and reliably than with…
- Conditions
- Spinal Cord Injury (=3 Years), Traumatic Brain Injury (TBI) Patients, Healthy Adult Participants
- Trial name
- NCT07873151
- Testing
- voice-activated call light
- Where
- United States
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- Quality Living, Inc.
Healthy Adult Participants
Neuroanatomically Informed fMRI Neurofeedback in Healthy Adults
This study will test and refine a type of brain training called functional magnetic resonance imaging (fMRI) neurofeedback in healthy adults.
- Trial name
- NCT07873710
- Testing
- Functional Connectivity fMRI Neurofeedback, ROI-Activity fMRI Neurofeedback
- Where
- United States
- Volunteers
- 15 people, healthy volunteers welcome
- Sponsor
- The University of Texas Health Science Center, Houston