Clinical trials: Healthy Adult Subjects
Healthy
A Study to Evaluate HB0034 in Healthy Adult Participants
The aim of this study is to investigate the safety and tolerability of HB0034 in healthy subjects following a single dose.
- Trial name
- NCT05064345
- Testing
- HB0034
- Where
- New Zealand
- Volunteers
- 56 people, healthy volunteers welcome
- Sponsor
- Shanghai Huaota Biopharmaceutical Co., Ltd.
Bacterial Infections
A Phase 1 TP-271 Oral PK Single Ascending Dose Study
The purpose of this study is to determine the safety and tolerability of up to 6 different single ascending oral doses of TP-271, ranging from 25 mg to 300 mg, in healthy adult male or female subjects.
- Trial name
- NCT03024034
- Testing
- TP-271
- Where
- United States
- Volunteers
- 56 people, healthy volunteers welcome
- Sponsor
- Tetraphase Pharmaceuticals, Inc
Healthy Volunteers
A Study to Assess Adverse Events, Tolerability and How Single and Ascending Oral Doses of Nacresertib Move Through the Body In Healthy Adult Participants
The objectives for this 2 Part study are to assess the safety, tolerability, and pharmacokinetics following single ascending oral doses of nacresertib in healthy adult participants (Part 1) and to assess the safety, tolerability…
- Trial name
- NCT07566130
- Testing
- nacresertib
- Where
- United States
- Volunteers
- 93 people, healthy volunteers welcome
- Sponsor
- AbbVie
Bone Tumor
Phase Ⅰ Clinical Study Protocol of GB223 Monoclonal Antibody Injection
The primary objective of this study is to evaluate the safety, tolerability and pharmacokinetic (PK) profiles of single dose of GB223 in healthy subjects; the secondary objective is to evaluate the immunogenicity and…
- Trial name
- NCT04178044
- Testing
- GB223,7mg/kg, GB223,21mg/kg, GB223,63mg/kg
- Where
- China
- Volunteers
- 44 people, healthy volunteers welcome
- Sponsor
- Genor Biopharma Co., Ltd.
Human Immunodeficiency Virus (HIV), HIV Pre-Exposure Prophylaxis
A Drug-Drug Interaction Study of MK 8527 With a Combined Oral Contraceptive (LNG/EE)
This study is designed to assess the effect of a single dose of MK-8527 on the single-dose pharmacokinetics (PK) and the safety and tolerability of levonorgestrel/ethinyl estradiol (LNG/EE) in healthy adult postmenopausal or…
- Trial name
- NCT06783192
- Testing
- MK-8527, LNG/EE
- Where
- United States
- Volunteers
- 14 people, healthy volunteers welcome
- Sponsor
- Merck Sharp & Dohme LLC
Therapeutic Equivalency
Fasted Bioequivalence Study of Primidone Tablets and Mysoline Tablets
The purpose of this study is to compare the bioequivalence of a test formulation of primidone tablets to an equivalent oral dose of the commercially available Mysoline®(primidone tablets) in adult subjects under fasting…
- Trial name
- NCT00685165
- Testing
- Primidone 50 mg Tablet, Primidone (Mysoline®) 50 mg Tablet
- Volunteers
- 22 people, healthy volunteers welcome
- Sponsor
- Mutual Pharmaceutical Company, Inc.
Arthritis, Gouty
The MAD Study of SSGJ-613 in Healthy Subjects
To evaluate the safety and tolerability of SSGJ-613 after multiple subcutaneous injections in healthy subjects.
- Trial name
- NCT05966701
- Testing
- SSGJ-613
- Where
- China
- Volunteers
- 36 people, healthy volunteers welcome
- Sponsor
- Sunshine Guojian Pharmaceutical (Shanghai) Co., Ltd.
Healthy Volunteers
A Study to Evaluate Adverse Events and How Single Ascending Doses of ABBV-141 Move Through the Body of Healthy Adult Western and Asian Participants
The purpose of this study is to assess the safety, tolerability, pharmacokinetics (PK) and immunogenicity after single ascending doses (SAD) of ABBV-141 in healthy adult Western and Asian participants.
- Trial name
- NCT06148181
- Testing
- ABBV-141
- Where
- United States
- Volunteers
- 41 people, healthy volunteers welcome
- Sponsor
- AbbVie
Parkinson's Disease (PD)
Relative Bioavailability Study of HNC364 Injectable Suspension
HNC364 is a new pro-drug of rasagiline as a long-acting injection for deep IM deltoid injection, for the treatment of Parkinson"s disease (PD).
- Trial name
- NCT06798519
- Testing
- HNC364 Injectable Suspension, Rasagiline Tablets
- Where
- United States
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Guangzhou Henovcom Bioscience Co. Ltd.
Healthy
Evaluation Of Safety, Tolerability And Pharmacokinetics Of Single And Multiple Doses Of PF-06730512
The purpose of this study is to determine the safety, tolerability and pharmacokinetics of escalating single and multiple intravenous (IV) infusions and subcutaneous (SC) injections of PF-06730512 in healthy subjects.
- Trial name
- NCT03146065
- Testing
- PF-06730512
- Where
- Belgium
- Volunteers
- 79 people, healthy volunteers welcome
- Sponsor
- Pfizer
Infection, Human Immunodeficiency Virus I
A Drug Interaction Study Evaluating Plasma GSK2248761 and GSK1349572 Pharmacokinetics in Healthy Adult Subjects.
This is a single-center, open-label, three-period, fixed-sequence cross over study in healthy adult subjects. A total of approximately 16 healthy subjects will be enrolled to provide data from 12 evaluable subjects.
- Trial name
- NCT01283100
- Testing
- GSK1349572, GSK2248761
- Where
- United States
- Volunteers
- healthy volunteers welcome
- Sponsor
- ViiV Healthcare
Asthma Severe Persistent Controlled
Phase I Clinical Trial of TQC2731 Injection
This is the first-in-human phase 1 trial of TQC2731 injection in healthy subjects and in patients with severe asthma to evaluate the safety, tolerability, pharmacokinetic characteristics and immunogenicity.
- Trial name
- NCT04923607
- Testing
- TQC2731
- Where
- China
- Volunteers
- 96 people, healthy volunteers welcome
- Sponsor
- Chia Tai Tianqing Pharmaceutical Group Co., Ltd.
Healthy
Effect of Probiotic Fermented Dairy Drinks on Intestinal Immune Response
The purpose of this study is to investigate whether two different fermented dairy drinks consumed daily could have an effect on the intestinal immune response in healthy subjects.
- Trial name
- NCT00987311
- Testing
- 1- Dairy drink containing probiotics A, 2- Dairy drink containing probiotics B, 3- Dairy drink without probiotics (control)
- Volunteers
- 33 people, healthy volunteers welcome
- Sponsor
- Danone Global Research & Innovation Center
Parkinson's Disease
A Study of Single and Multiple Doses of KW-6356 in Healthy Subjects
Phase I study to assess the safety, tolerability and pharmacokinetics of single and multiple doses of KW-6356 in healthy volunteers
- Trial name
- NCT03830528
- Testing
- KW-6356 Low Dose, KW-6356 Middle Dose, KW-6356 High Dose
- Where
- Japan
- Volunteers
- 48 people, healthy volunteers welcome
- Sponsor
- Kyowa Kirin Co., Ltd.
Hepatic Impairment, Healthy
An Open-label, Single-dose, Intravenous Administration Study of ONO-2745/CNS 7056 in Subjects With Chronic Hepatic Impairment
To evaluate and compare the pharmacokinetics and safety of ONO-2745/CNS 7056 in subjects with the hepatic impairment and matched healthy subjects.
- Trial name
- NCT01790607
- Testing
- ONO-2745 /CNS 7056
- Where
- 3 sites in United States
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- Ono Pharma USA Inc
Nonalcoholic Steatohepatitis (NASH)
The Tolerability , Pharmacokinetics and Pharmacodynamics Study of HEC96719 Tablets in Healthy Adult Subjects
This study is a safety, tolerability, and pharmacokinetics phase Ⅰstudy of HEC96719, in healthy subjects.This study is the healthy adult subjects single ascending-dose research
- Trial name
- NCT04194242
- Testing
- HEC96719 tablets
- Where
- China
- Volunteers
- 64 people, healthy volunteers welcome
- Sponsor
- Sunshine Lake Pharma Co., Ltd.
Healthy
Evaluation of Adhesion and Dermal Tolerability of EMSAM
Examine adhesive and dermal tolerability of EMSAm 6mg/24hr and 12mg/24hr in healthy elderly and non-elderly subjects.
- Trial name
- NCT00531596
- Testing
- EMSAM (Selegiline Transdermal System) 6mg/24Hr, EMSAM (Selegiline Transdermal System) 9mg/24Hr, EMSAM (Selegiline Transdermal System) 12mg/24hr
- Where
- 2 sites in United States
- Volunteers
- 300 people, healthy volunteers welcome
- Sponsor
- Somerset Pharmaceuticals
Healthy Subjects
A Study to Evaluate the Effect of Oral Mirabegron on the Heart in Healthy Males and Females
The objective of this study is to evaluate the effect of repeat oral dosing of mirabegron on ECG (electrocardiogram) measurements.
- Trial name
- NCT01199523
- Testing
- mirabegron, moxifloxacin
- Where
- 2 sites in United States
- Volunteers
- 352 people, healthy volunteers welcome
- Sponsor
- Astellas Pharma Inc
Healthy Volunteers
A Study of AZD4205 in Healthy Adult Subjects
This study is to assess the safety, tolerability, pharmacokinetics of AZD4205 following single and multiple ascending dose in healthy adult subjects, and to assess the effect of food on the pharmacokinetics of AZD4205.
- Trial name
- JACKPOT2 (NCT03728023)
- Testing
- AZD4205
- Where
- United States
- Volunteers
- 66 people, healthy volunteers welcome
- Sponsor
- Dizal Pharmaceuticals
Healthy
A Study to Investigate Safety, Tolerability, and Pharmacokinetics of JNJ-56136379 in Healthy Japanese Adult Participants
The purpose of this study is to investigate the safety, tolerability, and pharmacokinetics (PK) of JNJ-56136379 in healthy Japanese adult participants following oral administration of single doses from 25 milligram (mg) up to 600…
- Trial name
- NCT02933580
- Testing
- JNJ-56136379
- Where
- United States
- Volunteers
- 32 people, healthy volunteers welcome
- Sponsor
- Janssen Research & Development, LLC
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