Clinical trials: Healthy Condition
Idiopathic Pulmonary Fibrosis
A First in Human Study to Evaluate the Safety, Tolerability, Pharmacokinetics and Immunogenicity of PMG1015
This is a Phase 1A, first in human, randomized, double-blinded, placebo-controlled, dose escalation study of PMG1015 in healthy adult volunteers.
- Trial name
- NCT05022771
- Testing
- PMG1015 Dose 1, PMG1015 Dose 2, PMG1015 Dose 3
- Where
- Australia
- Volunteers
- 54 people, healthy volunteers welcome
- Sponsor
- Pulmongene Ltd.
Weight Loss, Pre Diabetes
Healthy Body Healthy Souls in the Marshallese Population
The primary aim is to pilot test a weight-loss intervention for Marshallese adults, referred to throughout as Healthy Bodies Healthy Souls (HBHS).
- Conditions
- Weight Loss, Pre Diabetes, Overweight and Obesity
- Trial name
- NCT03377244
- Testing
- HBHS, HBHS Policy, WORD DPP
- Where
- United States
- Volunteers
- 102 people, healthy volunteers welcome
- Sponsor
- University of Arkansas
Healthy Subjects
The Effects of Caffeine on Vestibular Evoked Myogenic Potentials in Healthy Subjects
The principal aim of this study is to evaluate the presence of changes in cervical vestibular evoked myogenic potentials (VEMPc) after acute intake of caffeine in healthy subjects.
- Trial name
- NCT01693809
- Testing
- Caffeine
- Where
- Brazil
- Volunteers
- 25 people, healthy volunteers welcome
- Sponsor
- Hospital do Servidor Publico Estadual
Ulcerative Colitis
TP0502-B-Pharmaco-Scintigraphic-Study
This is a Phase I, open-label, single-site trial to evaluate the drug release, using scintigraphic images and mesalazine plasma levels (PK) in healthy subjects. Overall, nine [9] subjects will be evaluated.
- Trial name
- NCT02306798
- Testing
- TP05
- Volunteers
- 9 people, healthy volunteers welcome
- Sponsor
- Tillotts Pharma AG
Healthy Volunteers, Hepatitis C Virus
Adaptive Phase I HCV Study With Nucleoside Analogue, in Combination With Interferon and Ribavirin
This is an adaptive Phase I study to evaluate RO5024048 in the following groups: Healthy Volunteers (Part 1 - Single Ascending Dose Study) -Enrollment completed Hepatitis C virus (HCV) genotype 1 infected patients who have failed…
- Trial name
- R7128 (NCT00382798)
- Testing
- RO5024048
- Where
- 9 sites in United States, New Zealand and 1 more
- Volunteers
- 75 people
- Sponsor
- Pharmasset
Acquired Brain Injury, Stroke
TMS-EEG for Cortical Excitability
This research study is being done to look at the safety and diagnostic benefit of conducting an TMS(transcranial magnetic stimulation)-EEG measured before and after a brief experimental stimulation session using investigational…
- Conditions
- Acquired Brain Injury, Stroke, Traumatic Brain Injury, Healthy
- Trial name
- NCT05472363
- Testing
- Electroencephalogram, Transcranial Magnetic Stimulation, Transcranial Direct Current Stimulation
- Volunteers
- healthy volunteers welcome
- Sponsor
- Mayo Clinic
Major Depression
Healthy Mood Internet Intervention Research Project
The purpose of the study is: 1. to study whether individuals WHO ARE NOT CURRENTLY SERIOUSLY DEPRESSED will participate in an online study to prevent clinical depression and 2.
- Trial name
- NCT01358487
- Testing
- Online self-help course plus live follow-up if needed, Online + incentives Follow-up Group
- Where
- United States
- Volunteers
- 116 people, healthy volunteers welcome
- Sponsor
- University of California, San Francisco
Childhood Obesity, Self-regulation
ONE PATH: Optimizing Nutrition Education for Parents and Teachers for Healthy Growth
This proposal uses an innovative methodological framework, the multiphase optimization strategy (MOST), to design an effective and efficient responsive feeding (RF) intervention that promotes child appetite self-regulation among…
- Conditions
- Childhood Obesity, Self-regulation, Appetite Regulation
- Trial name
- ONE PATH (NCT03817021)
- Testing
- ECE Provider, Parent Intervention, Child intervention
- Where
- United States
- Volunteers
- 1,461 people, healthy volunteers welcome
- Sponsor
- Penn State University
Diabetes Mellitus, Type 2, Aged
Promoting Healthy Habits With Elderlies Diabetics
Randomized clinical trial with the objective of evaluating the effectiveness of operative groups to promote healthy habits in elderlies diabetics.
- Conditions
- Diabetes Mellitus, Type 2, Aged, Health Behavior, Group Processes
- Trial name
- NCT02771821
- Testing
- Operative groups based on methodology of problematization
- Where
- Brazil
- Volunteers
- 202 people, healthy volunteers welcome
- Sponsor
- Universidade Federal de Pernambuco
Healthy
Megavec 400 mg (Imatinib Mesylate) in Healthy Adult Male Volunteers
The purpose of this Study is to Assess Safety and Pharmacokinetics of megavec 400 mg (Imatinib mesylate) under Fasted Conditions in Healthy Male Subjects.
- Trial name
- NCT01653314
- Testing
- Megavec, Glivec
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Daewoong Pharmaceutical Co. LTD.
Diabetes, Pre-diabetes
Metformin at the Cellular Level and Dosing for Diabetes Mellitus (DM)
The investigators know that metformin works at the level of the cells in the body by acting on a protein called Cyclic amine monophosphate- Response Binding Elements (CREB) binding protein or Constitutive Reverter of eIF2α…
- Conditions
- Diabetes, Pre-diabetes, Obesity
- Trial name
- NCT01876992
- Testing
- Metformin
- Where
- United States
- Volunteers
- 10 people, healthy volunteers welcome
- Sponsor
- Johns Hopkins University
Non-alcoholic Steatohepatitis
A Thorough QTC Study to Assess the Effect of Cotadutide on Cardiac Repolarization in Healthy Participants
This study will investigate the effect of multiple doses of cotadutide on the cardiac activity (QTc interval) of healthy participants.
- Trial name
- NCT05668936
- Testing
- Cotadutide, Moxifloxacin
- Where
- Germany
- Volunteers
- 31 people, healthy volunteers welcome
- Sponsor
- AstraZeneca
Diet, Healthy, Eating Behavior
SSS and the Impact of Portion Size on Daily Energy Intake
Reducing food portion size is a potential strategy to reduce energy intake. However, it remains unclear who is most susceptible to the portion size effect (PSE).
- Conditions
- Diet, Healthy, Eating Behavior, Obesity
- Trial name
- NCT05399836
- Testing
- Portion size manipulation
- Where
- United Kingdom
- Volunteers
- 47 people, healthy volunteers welcome
- Sponsor
- University of Liverpool
Healthy Diet, Obesity
Effect of Ultra-processed Versus Unprocessed Diets on Energy Metabolism
Protocol Number: 22DK0002 Title: Effects of Ultra-processed versus Unprocessed Diets on Energy Metabolism Background: Many diets worldwide include both processed and unprocessed foods.
- Trial name
- NCT05290064
- Testing
- Ultra-processed food, high energy density (UPF HL), Ultra-processed food, both low (UPF LL), Ultra-processed food, both high (UPF HH)
- Where
- United States
- Volunteers
- 38 people
- Sponsor
- National Institutes of Health Clinical Center (CC)
Healthy
Pravastatin 80 mg Tablets Dosed in Healthy Subjects Under Non-Fasting Conditions
This study compared the relative bioavailability (rate and extent of absorption) of Pravastatin Sodium Tablets 80 mg by Teva Pharmaceutical Industries, Ltd.
- Trial name
- NCT00829309
- Testing
- Pravastatin
- Where
- United States
- Volunteers
- 16 people, healthy volunteers welcome
- Sponsor
- Teva Pharmaceuticals USA
Childhood Obesity
Turn up the HEAT - Healthy Eating and Activity Time in Summer Day Camps
The investigators long-term goal is to increase the number of Summer Day Camps (SDC) that meet the National Afterschool Association Healthy Eating and Physical Activity (HEPA) Standards.
- Trial name
- HEPA (NCT02161809)
- Testing
- Healthy Eating and Physical Activity
- Where
- United States
- Volunteers
- 1,000 people
- Sponsor
- University of South Carolina
Influenza
A Prospective Epidemiological Cohort Study Evaluating Occurrences of Influenza-like Illness.
This Prospective epidemiological cohort study is being conducted in order to generate epidemiological data in support of Osivax's clinical development of a broad spectrum influenza vaccine based upon the internal influenza…
- Trial name
- NCT05184387
- Testing
- Blood samples
- Where
- Belgium
- Volunteers
- 66 people, healthy volunteers welcome
- Sponsor
- Osivax
Diabetes
Healthy Living for You
The goal of the study is to conduct the Healthy Living with Diabetes (HLWD) program among Black individuals in a culturally appropriate manner. This study will involve 24-30 participants in total.
- Trial name
- NCT05917093
- Testing
- Culturally tailored HLWD
- Where
- 2 sites in United States
- Volunteers
- 32 people
- Sponsor
- University of Wisconsin, Madison
Covid19, HIV-1-infection
An Open-label Clinical Study of the Pharmacokinetics and Safety of Elsulfavirine, 200 mg Tablets, With Single and Multiple Oral Administration in Healthy Volunteers
An open-label clinical study of the pharmacokinetics and safety of Elsulfavirine, 200 mg tablets, with single and multiple oral administration in healthy volunteers.
- Trial name
- NCT05148754
- Testing
- Elsulfavirine
- Where
- Russia
- Volunteers
- 15 people, healthy volunteers welcome
- Sponsor
- Viriom
Streptococcus Pneumonia
PREVENTING PNEUMOcoccal Disease Through Vaccination (Study 2)
To determine the effect of PCV-13 and PPV-23 vaccination versus control on experimental pneumococcal colonisation of 2 clades of serotypes 3 and 6B at 1 month and 6 months post vaccination respectively, using the EHPC model.
- Trial name
- Pneumo 2 (NCT04974294)
- Testing
- PPV23, PCV13, Saline for injection
- Where
- United Kingdom
- Volunteers
- 516 people, healthy volunteers welcome
- Sponsor
- Liverpool School of Tropical Medicine
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