Clinical trials: Healthy Control Group
Healthy
A Study in Healthy Men to Test How Well Different Doses of BI 1569912 Are Tolerated
The main objectives of this trial are to investigate (1) safety, tolerability, pharmacokinetics and pharmacodynamics following multiple rising doses of BI 1569912; (2) tolerability of BI 1569912 in an up-titrating dosing scheme.
- Trial name
- NCT04978506
- Testing
- BI 1569912
- Where
- Germany
- Volunteers
- 83 people, healthy volunteers welcome
- Sponsor
- Boehringer Ingelheim
Healthy
A Multiple Increasing Dose Safety and Tolerability Study After Inhalation Administration of BIIX 1 XX in Healthy Male Volunteers
The objective of the present study is to obtain information about the safety and tolerability of multiple increasing doses of BIIX 1 XX and to obtain preliminary pharmacokinetic data
- Trial name
- NCT02198313
- Testing
- BIIX 1 XX - D1, BIIX 1 XX - D2, BIIX 1 XX - D3
- Volunteers
- 8 people, healthy volunteers welcome
- Sponsor
- Boehringer Ingelheim
Health, Subjective
Mulberry Leaf Extract Capsule on Blood Glucose Control in Healthy Volunteers
Volunteers will be divided into 4 groups which are mulberry leaf extract 6 mg capsule, mulberry leaf extract 12 mg capsule, mulberry leaf extract 18 mg capsule, and placebo capsule group.
- Trial name
- NCT06488326
- Testing
- Mulberry leaf extract 6 mg capsule, Mulberry leaf extract 12 mg capsule, Mulberry leaf extract 18 mg capsule
- Volunteers
- 56 people, healthy volunteers welcome
- Sponsor
- Chulalongkorn University
Sleep Apnea, Obstructive
Effect of Desipramine on Genioglossus Muscle Activity in Healthy Adults Study A
Obstructive sleep apnea (OSA) is common and has major health implications but treatment options are limited. OSA patients show a marked reduction in upper airway (UA) dilator muscle activity at sleep onset and this phenomenon…
- Trial name
- DESOSA (NCT02428478)
- Testing
- Desipramine
- Where
- United States
- Volunteers
- 17 people, healthy volunteers welcome
- Sponsor
- Brigham and Women's Hospital
Physical Fitness
BPIT 5-Week Multi-Site Study: Movement Efficiency, Mobility & Neuromuscular Adaptation
This prospective, multi-site, single-arm interventional study evaluates the 5-Line Principle of Balanced Progressive Intensity Training (BPIT) over 5 weeks in healthy adults aged 18-65 years.
- Trial name
- BPIT_5LINE_369 (NCT07256717)
- Testing
- Balanced Progressive Intensity Training (BPIT) 5-Line Method
- Where
- 10 sites in United States, India
- Volunteers
- 369 people, healthy volunteers welcome
- Sponsor
- MMSx Authority Institute for Movement Mechanics & Biomechanics Research Inc.
Healthy
Lubiprostone, Colonic Motility and Sensation
This study is being done to evaluate the effects of lubiprostone, a drug approved and used for constipation, on pattern of contractions of the colon and the colon's sensitivity to distension.
- Trial name
- NCT00953043
- Testing
- lubiprostone, Bowel preparation
- Where
- United States
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Mayo Clinic
Post-Operative Nausea and Vomiting (PONV)
Single Dose Safety Study for Compound to Treat Post-Operative Nausea and Vomiting (PONV)
The purpose of this study is to describe the safety and tolerability and pharmacokinetics of a single intravenous administration of the new, Sulfobutyl Ether-7-Beta-Cyclodextrin (Captisol™) based, formulation in Healthy Adult…
- Trial name
- NCT01290133
- Testing
- GW597599
- Where
- Australia
- Volunteers
- 55 people, healthy volunteers welcome
- Sponsor
- Accenture
Healthy
Influence of Telmisartan and Lacidipine, Combined or Alone, on QT Interval in Healthy Volunteers
Assessment of the influence of telmisartan, lacidipine and their combination on the QTC interval of the ECG
- Trial name
- NCT02264158
- Testing
- Telmisartan high, Telmisartan low, Lacidipine high
- Volunteers
- 149 people, healthy volunteers welcome
- Sponsor
- Boehringer Ingelheim
Drug Interactions
S(+)-Ibuprofen Effects on Asprin Treated Volunteers
The purpose of this clinical trial is to determine whether S(+)-ibuprofen affect the platelet inhibition under steady state acetylsalicylic acid conditions.
- Trial name
- NCT00442585
- Testing
- S(+)-ibuprofen
- Where
- Austria
- Volunteers
- 72 people, healthy volunteers welcome
- Sponsor
- Gebro Pharma GmbH
Renal Insufficiency
Pharmacokinetics (PK) and Metabolism of FTY720 in Patients With Severe Renal Impairment and Healthy Matched Subjects.
The purpose of this study is to compare the pharmacokinetics of FTY720 and its metabolites in patients with severe renal insufficiency and in matched, healthy volunteers.
- Trial name
- NCT00731523
- Testing
- fingolimod (FTY720)
- Where
- Russia
- Volunteers
- 18 people, healthy volunteers welcome
- Sponsor
- Novartis
Healthy Study Participants, Participants With Mild Asthma
A Study to Assess the Pulmonary Safety of Staccato Alprazolam in Healthy Study Participants and in Study Participants With Mild Asthma
The purpose of the study is to assess the pulmonary safety of Staccato alprazolam in healthy study participants and in and study participants with mild asthma
- Trial name
- NCT04802746
- Testing
- Alprazolam
- Where
- 2 sites in United States
- Volunteers
- 78 people, healthy volunteers welcome
- Sponsor
- UCB Biopharma SRL
Healthy
Study to Evaluate Different Extended Release (ER)-Formulations and Multiple Ascending Dosing of AZD3241
The aims of the study are to assess the safety, tolerability and pharmacokinetics of ER tablets of AZD3241 following multiple ascending doses administered to healthy male and female subjects including the effect of food.
- Trial name
- NCT00914303
- Testing
- AZD3241
- Where
- Sweden
- Volunteers
- 77 people, healthy volunteers welcome
- Sponsor
- AstraZeneca
Healthy Subjects
Efficacy of 8 vs 4 Sessions Mindfulness-based Programs in a Non-clinical Population
The aim of this study was to assess and compare the efficacy of a standard 8-weeks protocol based on the Mindfulness Based Stress Reduction MBSR program versus a 4-week shortened version of the protocol in the improvement of…
- Trial name
- NCT02643927
- Testing
- standard 8-weeks MBSR, 4-week shortened MBSR
- Volunteers
- 99 people, healthy volunteers welcome
- Sponsor
- Hospital Miguel Servet
Anti-Psychotic, Management of Manifestations of Psychotic Disorders
Assessment of Intra-subject Variability in the Bioavailability of Chlorpromazine Hydrochloride
Cycle Pharmaceuticals Ltd. (Cycle) is developing an oral tablet formulation of Chlorpromazine Hydrochloride and intends to conduct bioequivalence trials to demonstrate its similarity to the RLD.
- Conditions
- Anti-Psychotic, Management of Manifestations of Psychotic Disorders, Treatment of Schizophrenia, Control Nausea and Vomiting
- Trial name
- NCT02943213
- Testing
- Chlorpromazine Hydrochloride
- Where
- South Africa
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- Cycle Pharmaceuticals Ltd.
Lung Cancer
Thermal Signature of Patients Undergoing Radiation Therapy
The goal of this clinical research study is to evaluate whether thermal imaging (recording body temperature) can be used to check the body's response to cancer therapy.
- Trial name
- NCT00508313
- Testing
- Thermal Imaging
- Where
- United States
- Volunteers
- healthy volunteers welcome
- Sponsor
- M.D. Anderson Cancer Center
Healthy
Study to Investigate Safety and Tolerability of BI 1744 CL in Free Dose Combination With Tiotropium Bromide Both Administered by Respimat® in Healthy Male Volunteers
Study to investigate safety and tolerability of single, inhaled doses (2.5 μg, 5 μg, 10 μg, 20 μg and 40 μg) of BI 1744 CL in free dose combination with tiotropium bromide 5 μg (for doses up to and including 20 μg BI 1744 CL) and…
- Trial name
- NCT02259946
- Testing
- BI 1744 CL, Tiotropium bromide
- Volunteers
- 48 people, healthy volunteers welcome
- Sponsor
- Boehringer Ingelheim
Healthy, Tooth Extraction
Capsaicin to Control Pain Following Third Molar Extraction
Capsaicin to Control Pain Following Third Molar Extraction Summary: This study will test the effectiveness of the drug capsaicin in controlling pain after third molar (wisdom tooth) extraction.
- Trial name
- NCT00088686
- Testing
- Capsaicin (Intramucosal Injection)
- Where
- United States
- Volunteers
- 75 people
- Sponsor
- National Institute of Dental and Craniofacial Research (NIDCR)
Healthy
Effects of Intranasal Oxytocin on Emotion Regulation
The aim is to examine whether intranasal oxytocin will influence the individuals' emotion regulation ability and related neural mechanisms.
- Trial name
- NCT03055546
- Testing
- Oxytocin
- Where
- China
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- University of Electronic Science and Technology of China
Child Behavior, Sedentary Behavior
Strengthening Child Social-Emotional and Lifestyle Health in Families Experiencing Stress
This study evaluates feasibility and preliminary efficacy of a parent-based prevention program to promote social-emotional and lifestyle behavior health among 3- to 9-year-old children in families experiencing major stressors.
- Conditions
- Child Behavior, Sedentary Behavior, Self-regulation, Parenting
- Trial name
- NCT06163703
- Testing
- Family Life Skills Triple P
- Where
- United States
- Volunteers
- 86 people, healthy volunteers welcome
- Sponsor
- University of South Carolina
Enteric Fever
Study to Evaluate the Safety, Tolerability and Immunogenicity of a Potential Enteric Fever Vaccine
A Phase 1, randomised, double-blind, placebo-controlled, parallel group study in 45 healthy participants aged 18 to 45 years inclusive.
- Trial name
- NCT04349553
- Testing
- ZH9PA and ZH9, ZH9PA
- Where
- United Kingdom
- Volunteers
- 46 people, healthy volunteers welcome
- Sponsor
- Prokarium Ltd
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