Clinical trials: Healthy Control Subjects
Healthy Female Subjects
Comparison of Pulse Wave and Blood Pressure Measurements Before, During and After Ergometry in Healthy Women
The objective of this randomized, controlled single blind study is to compare pulse wave and blood pressure measurements before, during and after exercise ergometry in healthy female subjects.
- Trial name
- NCT03792893
- Testing
- Ergometry H, Ergometry L
- Where
- Germany
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- ARCIM Institute Academic Research in Complementary and Integrative Medicine
Influenza
Safety Study of Single Administration Intravenous Treatment for Influenza
The purpose of this study is to characterize the safety and pharmacology of single administrations of AVI-7100, a candidate treatment for influenza.
- Trial name
- NCT01375985
- Testing
- AVI-7100
- Where
- United States
- Volunteers
- 8 people, healthy volunteers welcome
- Sponsor
- Sarepta Therapeutics, Inc.
Malaria
Study to Assess Safety, Tolerability and Phamacokinetics of KAE609 Administered Intravenously in Healthy Subjects
This was a randomized, subject and investigator-blinded, placebo-controlled, single and multiple ascending intravenous (iv) dose study in healthy subjects to assess the safety and tolerability of KAE609 given in the vein.
- Trial name
- NCT04321252
- Testing
- KAE609
- Where
- Belgium
- Volunteers
- 57 people, healthy volunteers welcome
- Sponsor
- Novartis Pharmaceuticals
Healthy, Constipation
Effect of a Fermented Milk Product With Probiotics Alone or in Combination With Fibers on Constipation Symptoms
First experimental study (Proof Of Concept) to investigate bowel function parameters on which a fermented milk product with probiotics alone or in association with fibers has a potential effect.
- Trial name
- NCT02461485
- Testing
- Fermented milk product containing Probiotics, Fermented Milk Product containing Probiotics + Fibers C, Fermented Milk Product containing Probiotics + Fibers W
- Where
- Ireland
- Volunteers
- 153 people, healthy volunteers welcome
- Sponsor
- Danone Global Research & Innovation Center
Hereditary Angioedema (HAE)
Phase 1 Study to Assess the Safety, Tolerability, and Pharmacokinetics of Recombinant Human C1 Esterase Inhibitor in Healthy Adult Subjects
This trial is looking to gain information about the safety and tolerability of an investigational treatment (SHP623) in healthy adult volunteers.
- Trial name
- NCT02663687
- Testing
- Recombinant human C1 esterase inhibitor, SHP623
- Where
- United States
- Volunteers
- 48 people, healthy volunteers welcome
- Sponsor
- Shire
Influenza A H3N2
Study Examining PrEP-001 in Healthy Subjects
Phase 2 study, looking at the prophylactic efficacy, safety and tolerability to a repeated nasal dose of study drug after being infected with Influenza A/Perth/16/2009 (H3N2) virus.
- Trial name
- NCT03220048
- Testing
- PrEP-001
- Where
- United Kingdom
- Volunteers
- 66 people, healthy volunteers welcome
- Sponsor
- Hvivo
Healthy
Safety, Tolerability, Pharmacodynamic and Pharmacokinetic Effects of Single and Multiple-Doses of ATF936 and AXT914 Administered Orally in Healthy Subjects.
This is a first-in-human study and is designed to evaluate the safety, tolerability, pharmacodynamic and pharmacokinetic effects of a single and multiple-doses of ATF936 and AXT914 administered orally in healthy subjects.
- Trial name
- NCT00417261
- Testing
- ATF936, AXT914
- Where
- United States
- Volunteers
- 65 people, healthy volunteers welcome
- Sponsor
- Novartis
Healthy Volunteer
A Single- and Multiple-Dose Study of the Pharmacokinetics of TAK-491 in Healthy Chinese Participants
The purpose of this study is to assess the pharmacokinetics and safety of single- and multiple-dose of TAK-491 in healthy Chinese participants.
- Trial name
- NCT02541669
- Testing
- TAK-491
- Where
- China
- Volunteers
- 64 people, healthy volunteers welcome
- Sponsor
- Takeda
Moderate to Severe Plaque Psoriasis
Randomized, Double Blinded, Placebo Controlled, Single Dose Escalation Study of 608 in Healthy Subjects
This is a first-in-human, phase 1, single-center, randomized, double blinded, placebo-controlled, single dose-escalation study to evaluate the safety, tolerability, PK, of 608 following subcutaneous injection in healthy subjects.
- Trial name
- NCT04367441
- Testing
- 608
- Where
- China
- Volunteers
- 62 people, healthy volunteers welcome
- Sponsor
- Sunshine Guojian Pharmaceutical (Shanghai) Co., Ltd.
Acanthamoeba Keratitis
Safety and Tolerability of Preservative-free Polyhexamethylene Biguanide (PHMB) Ophthalmic Solution in Healthy Subjects
Randomized, double-masked, placebo-controlled, multiple center, parallel-group Phase 1 study to evaluate the safety and tolerability of 3 doses of preservative-free PHMB ophthalmic solution compared to placebo in healthy subjects
- Trial name
- NCT02506257
- Testing
- 0.04% PHMB, 0.06% PHMB, 0.08% PHMB
- Volunteers
- 90 people, healthy volunteers welcome
- Sponsor
- SIFI SpA
Healthy
A Study to Evaluate Single-dose of HB0056 in Healthy Adult Participants
The aim of this study is to investigate the safety and tolerability of HB0056 in healthy subjects following single-dose.
- Trial name
- NCT06612970
- Testing
- HB0056
- Where
- New Zealand
- Volunteers
- 46 people, healthy volunteers welcome
- Sponsor
- Shanghai Huaota Biopharmaceutical Co., Ltd.
Tuberculosis
A Phase 1 Study to Evaluate the Safety, Tolerability, and Pharmacokinetics of TBA-354 in Healthy Adult Subjects
The objective of this study is to evaluate the safety and tolerability of single oral doses of TBA-354 when administered to healthy adult subjects.
- Trial name
- NCT02288481
- Testing
- TBA-354
- Where
- United States
- Volunteers
- 48 people, healthy volunteers welcome
- Sponsor
- Global Alliance for TB Drug Development
Healthy
A Study to Investigate the Safety, Tolerability, and Pharmacokinetics of JNJ-39393406 in Healthy Participants
The purpose of the study is to evaluate the safety and tolerability of multiple dose administration of JNJ-39393406 in young healthy participants, and subsequently in healthy elderly participants.
- Trial name
- NCT02023255
- Testing
- JNJ-39393406
- Where
- Belgium
- Volunteers
- 88 people, healthy volunteers welcome
- Sponsor
- Johnson & Johnson Pharmaceutical Research & Development, L.L.C.
Healthy, Type 2 Diabetes Mellitus
Multiple Ascending Dose Study of GMC-252-L-Lys Salt in Healthy Subjects and Type 2 Diabetics
The purpose of this study is to assess the safety, tolerability and pharmacokinetics (PK) of multiple oral doses of GMC-252-L-Lysine salt (GMC-252) in healthy subjects and type 2 diabetics.
- Trial name
- NCT02744820
- Testing
- GMC-252-L-Lysine Salt
- Where
- 2 sites in United Kingdom
- Volunteers
- 34 people, healthy volunteers welcome
- Sponsor
- Genmedica Therapeutics S.L.
Alcohol Use, Unspecified
Effect of Different Foods Together With a Small Dose of Alcohol on Alcohol Levels in Healthy Subjects
Alcohol consumption is prevalent and frequently excessive and its use poses a major risk to both personal and public health. In the U.S., every month over 25% of adults and 40% of college students drink until their blood alcohol…
- Trial name
- NCT03867812
- Testing
- SOBAR, Control food, Full meal
- Where
- Canada
- Volunteers
- 21 people, healthy volunteers welcome
- Sponsor
- Zeno Functional Foods, LLC
Safety Issues
A Phase1 Study of VIB9600
Overall design: Single-center, randomized, blinded, placebo-controlled single- and multiple-ascending dose study in healthy adult subjects.
- Trial name
- NCT03621605
- Testing
- VIB9600
- Where
- United States
- Volunteers
- 24 people, healthy volunteers welcome
- Sponsor
- Amgen
Dermatitis, Atopic, Pruritus
Study to Evaluate ASN008 Topical Gel (TG)
This is an ascending dose escalation study to test the safety, tolerability and preliminary efficacy of ASN008 TG in first-in-human subjects
- Conditions
- Dermatitis, Atopic, Pruritus, Dermatitis Eczema
- Trial name
- NCT03798561
- Testing
- ASN008 TG
- Where
- 5 sites in United States, Canada
- Volunteers
- 24 people, healthy volunteers welcome
- Sponsor
- Asana BioSciences
Healthy
Tramadol to Improve Its Detection in Biological Matrices in Anti-doping Controls
Orally single dose administration of Tramadol 75 mg for ultra-rapid metabolizers and 100 mg for extensive and poor metabolizers will be administered with the objective to evaluate urine and blood concentrations in healthy…
- Trial name
- NCT05925686
- Testing
- Tramadol.
- Where
- Spain
- Volunteers
- 25 people, healthy volunteers welcome
- Sponsor
- Parc de Salut Mar
Healthy Adult Subjects
A Phase I Study of TS-172 in Healthy Adult Subjects (Single and Multiple Doses)
A Phase 1, Single-Center, Randomized, Double-blind, Placebo-Controlled Study to Evaluate the Safety, Pharmacokinetics, and Pharmacodynamics of Single Ascending and Multiple Dose of TS-172 in Healthy Adult Subjects
- Trial name
- NCT04979572
- Testing
- TS-172
- Where
- Japan
- Volunteers
- 41 people, healthy volunteers welcome
- Sponsor
- Taisho Pharmaceutical Co., Ltd.
Healthy Subjects
Single Ascending Dose Study of TD-1439 in Healthy Subjects
Single ascending dose study to evaluate the safety, tolerability, pharmacokinetics, and pharmacodynamics of TD-1439 in healthy subjects
- Trial name
- NCT02903095
- Testing
- TD-1439
- Where
- United States
- Volunteers
- 66 people, healthy volunteers welcome
- Sponsor
- Theravance Biopharma
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