Clinical trials: Healthy Control Subjects
Alcohol Use Disorder (AUD), Healthy Controls Group - Age and Sex-matched
Imaging Mitochondrial Complex-I in Alcohol Use Disorder
Studies proposed in this application will image mitochondrial Complex-I (MCI-I) and cerebral glucose metabolism (CGM) in alcohol use disorder (AUD) and matched healthy controls
- Trial name
- NCT07825818
- Testing
- [F-18]BCPP-EF, [F-18]FDG
- Where
- United States
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Rajesh Narendran
Acute Stroke, Chronic Stroke Patient
Unimanual Versus Bimanual Motor Skill Learning in Acute and Chronic Stroke
To test the capacity of healthy individuals, chronic and acute stroke patients to learn and retain a complex unimanual or bimanual motor skill, trained on the neurorehabiliation robot REAplan® et the Dextrain® device.
- Conditions
- Acute Stroke, Chronic Stroke Patient, Healthy Individuals (Controls), Stroke (Subacute)
- Trial name
- MLAS6 (NCT07826832)
- Testing
- REAplan®, Dextrain® Manipulandum
- Where
- Belgium
- Volunteers
- 200 people, healthy volunteers welcome
- Sponsor
- University Hospital of Mont-Godinne
Stroke, Acute, Stroke (Subacute)
Inter-Limb Transfer in Acute Stroke
This study aims to investigate whether the improvements achieved through motor skill learning (MSkL) with the ipsilesional upper limb (UL) are transferred to the contralesional UL during the (sub)acute stroke phase, and to…
- Conditions
- Stroke, Acute, Stroke (Subacute), Healthy Individuals (Controls), Chronic Stroke Patients
- Trial name
- MLAS5 (NCT07822633)
- Testing
- REAplan®, Dextrain Manipulandum®
- Where
- 2 sites in Belgium
- Volunteers
- 250 people, healthy volunteers welcome
- Sponsor
- University Hospital of Mont-Godinne
Cocaine Use Disorder, Healthy Controls Group - Age and Sex-matched
Imaging Mitochondrial Complex-I in Cocaine Use Disorder: a [F-18]BCPP-EF PET Study
Studies proposed in this application will image mitochondrial Complex-I in cocaine use disorder (CUD) and matched healthy controls
- Trial name
- NCT07773649
- Testing
- [F-18]BCPP-EF
- Where
- United States
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Rajesh Narendran
Healthy Controls, Pregnancy
A Repository to Study Host-Microbiome Interactions in Health and Disease
Background: The microbiome is the bacteria and other microorganisms that live inside and on the body. The microbiome is important for our health. Researchers study how the microbiome help people stay healthy.
- Conditions
- Healthy Controls, Pregnancy, Pediatric Illnesses, Inflammatory Diseases
- Trial name
- NCT05656378
- Where
- United States
- Volunteers
- 600 people, healthy volunteers welcome
- Sponsor
- National Institute of Allergy and Infectious Diseases (NIAID)
Healthy Control, Opioid Use Disorder
OMAR Opioid Use Disorder
The goal of this research study is to examine the endocannabinoid (eCB) function in vivo in individuals with opioid use disorder (OUD) by measuring cannabinoid receptor 1 (CB1R) availability.
- Trial name
- NCT05683184
- Testing
- [11C]OMAR
- Where
- United States
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Yale University
Posterior Fossa Brain Tumor Group, Healthy Control Group
Physical Performance and Quality of Life in Children With Brain Tumors
This study is designed to assess physical performance and quality of life in children with posterior fossa brain tumors compared to healthy children.
- Trial name
- NCT07810673
- Where
- Egypt
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Sarah Mohammed El-Abasiri
Healthy Controls
Safety and Tolerability Study of VVZ-2471 in Healthy Volunteers
The goal of this study is to do follow-up testing on the safety and tolerability of an experimental (not FDA approved) medication. This study is seeking non-illicit drug using adults to test the medication.
- Trial name
- NCT07531316
- Testing
- VVZ-2471 for 14-day intervention
- Where
- United States
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Virginia Commonwealth University
Healthy Control
Massage: Neuroimaging and Correlates of Response - 6-week Study
This study will help find out if massage and touch therapies change brain activity and reduce the symptoms of anxiety. Massage therapy has well known health benefits.
- Trial name
- NCT07190326
- Testing
- Swedish Massage Therapy, Light Touch Control
- Where
- United States
- Volunteers
- 46 people, healthy volunteers welcome
- Sponsor
- University of Utah
Systemic Lupus Erthematosus, Sjogren's Syndrome
Mass Spectrometry-based Immune Profiling in Autoimmune Diseases
Based on mass spectrometry flow method, this study analyzed the typing of new T, B, NK and DC cell subsets in peripheral blood of common autoimmune diseases and their correlation with disease activity, aiming at establishing an…
- Conditions
- Systemic Lupus Erthematosus, Sjogren's Syndrome, Inflammatory Myopathies, Systemic Sclerosis (SSc)
- Trial name
- NCT07188285
- Where
- China
- Volunteers
- 500 people, healthy volunteers welcome
- Sponsor
- Peking University People's Hospital
Cocaine Use Disorder, Healthy Controls
Aberrant Synaptic Plasticity in Cocaine Use Disorder: A 11C-UCB-J PET Study
The purpose of this research study is to measure synaptic density in the brain comparing individuals with cocaine use disorder to healthy controls.
- Trial name
- NCT04721418
- Testing
- 11C-UCB-J
- Where
- United States
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- Yale University
Chronic Neck Pain, Healthy (Controls)
Accessory Inspiratory Muscles in Chronic Neck Pain
This cross-sectional case-control study aims to investigate the ultrasonographic structural and functional characteristics of accessory inspiratory muscles in individuals with chronic non-specific neck pain and compare them with…
- Trial name
- AIM-CNP (NCT07782099)
- Testing
- Diaphragm Ultrasonography, Anterior Scalene Muscle Ultrasonography, Upper Trapezius Muscle Ultrasonography
- Where
- Turkey (Türkiye)
- Volunteers
- 10 people, healthy volunteers welcome
- Sponsor
- Kocaeli Sağlık ve Teknoloji Üniversitesi
Healthy, Health Adult Subjects
Effect of Magnesium Supplementation on Sleep Quality and Cognitive Function in Saudi Adults
The goal of this clinical trial was to evaluate whether magnesium citrate supplementation improved sleep quality and cognitive function in healthy Saudi adults. It also assessed the effects of magnesium on selected blood markers.
- Conditions
- Healthy, Health Adult Subjects, Healthy Participants, Healthy Adult Participants
- Trial name
- NCT07515417
- Testing
- Magnesium 400Mg
- Where
- Saudi Arabia
- Volunteers
- 41 people
- Sponsor
- Umm Al-Qura University
Type 2 Diabetes, Healthy (Controls)
Specimen and Data Collection in South Carolina Medicaid-Enrolled Patients With Type 2 Diabetes (T2D) and Metabolically Healthy Controls
The primary purpose of this study is to use multiomic data in combination with clinical assessments, electronic health records, cognitive and mood assessments, wearable technologies and lifestyle/behavioral data to identify data…
- Trial name
- BRISK 2 (NCT07731399)
- Testing
- Not applicable- observational study
- Where
- 2 sites in United States
- Volunteers
- 1,200 people, healthy volunteers welcome
- Sponsor
- Guardian Research Network, Inc.
Healthy Controls
Reliability of [18F]-FTC-146 Brain Uptake in Healthy Controls
The purpose of this study is to understand the reliability of [18F]-FTC-146 brain uptake in healthy controls.
- Trial name
- rSIG (NCT03649555)
- Testing
- [18F]-FTC-146
- Where
- United States
- Volunteers
- 5 people, healthy volunteers welcome
- Sponsor
- Stanford University
Healthy Controls
Identification of a Safe and Non-Psychedelic Dose of Psilocybin
This randomized, double-blind, placebo-controlled, single ascending dose study will evaluate psilocybin in healthy adult subjects.
- Trial name
- NCT07710027
- Where
- Canada
- Volunteers
- 56 people, healthy volunteers welcome
- Sponsor
- Diamond Therapeutics Inc.
Prediabetes, Healthy (Controls)
Effects of Exogenous Ketones on Cognitive Function in Older Adults With Prediabetes?
Brief Summary The goal of this clinical trial is to learn whether older adults with prediabetes, but no diagnosed cognitive impairment, show early changes in brain energy use and thinking speed compared to older adults with…
- Trial name
- NCT07546409
- Testing
- Ketone Monoester (KE)
- Where
- 2 sites in United States
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- University of Alabama at Birmingham
Healthy Control
Auditory Stimulation Effect on Brain Oscillations and Sleep Dependent Learning
The investigators are testing the impact of quiet sounds played during sleep on brain oscillations and memory.
- Trial name
- NCT06688526
- Testing
- Quiet Sounds
- Where
- United States
- Volunteers
- healthy volunteers welcome
- Sponsor
- Massachusetts General Hospital
Pancreatic Cancer, Thyroid Cancer
Integrated Cancer Repository for Cancer Research
The iCaRe2 is a multi-institutional resource created and maintained by the Fred \& Pamela Buffett Cancer Center to collect and manage standardized, multi-dimensional, longitudinal data and biospecimens on consented adult cancer…
- Conditions
- Pancreatic Cancer, Thyroid Cancer, Lung Cancer, Esophageal Cancer
- Trial name
- iCaRe2 (NCT02012699)
- Where
- 42 sites in United States
- Volunteers
- 999,999 people, healthy volunteers welcome
- Sponsor
- University of Nebraska
Bronchiectasis Adult, Healthy Controls Group - Age and Sex-matched
Cardiopulmonary Responses to 6-Minute Stepper Test in Bronchiectasis Versus Healthy Controls
Individuals with bronchiectasis exhibit productive cough and recurrent lung infections as well as reduced exercise capacity, physical activity level, and respiratory and peripheral muscle strength.
- Trial name
- NCT06631261
- Testing
- No intervention; Observational study
- Where
- Turkey (Türkiye)
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Hacettepe University