Clinical trials: Healthy Corneas
Healthy Cornea
Evaluation of Corneal Endothelium Health Following Articaine Ophthalmic Solution Administration
The goal of this clinical trial is to evaluate the corneal endothelium health of eyes treated with articaine ophthalmic solution in adult participants.
- Trial name
- NCT07838129
- Testing
- Articaine (CYKLX), Vehicle
- Volunteers
- 165 people, healthy volunteers welcome
- Sponsor
- Laboratoires Thea
Keratoconus, Artificial Intelligence, Support Vector Machine
Efficiency of an Algorithm Derived From Corneal Tomography Parameters to Distinguish Highly Susceptible Corneas to Ectasia From Healthy
The objective of this study was to identify and build an algorithm through an imaging process using a support vector machine (SVM) with the tomography variables of cases with, KC, highly susceptible corneas to ectasia (HSCE), and…
- Trial name
- NCT04313387
- Testing
- Corneal tomography multivariate index derived from a support vector machine (CTMVI).
- Volunteers
- 588 people
- Sponsor
- Gildasio Castello de Almeida Junior
Keratoconus, Forme Fruste Keratoconus
Corneal Biomechanical Properties and Anterior Segment Parameters, in Forme Fruste Keratoconus
The present study attempts to evaluate the diagnostic capacity of a) anterior segment parameters b) biomechanical metrics and c) a combination model, in differentiating Forme Fruste Keratoconus (FFK) from healthy corneas.
- Trial name
- NCT01448408
- Where
- Greece
- Sponsor
- Democritus University of Thrace
Eyelid Diseases
Clinical Safety Study on an Eyelid Warming Device to Evaluate the Eyelid and Cornea Temperature in Healthy Volunteers
The eyelid warming device is designed to relieve the symptoms of dysfunction of the glands in the eyelids. Prospective, non comparative, open, monocentre study.
- Trial name
- NCT01086943
- Testing
- LT2420
- Where
- United Kingdom
- Volunteers
- 25 people, healthy volunteers welcome
- Sponsor
- Laboratoires Thea
Keratoconus
Astigmatic Vector Analysis of Posterior Cornea - a Comparison Among Healthy, Forme Fruste and Overt Keratoconus Corneas
The main purpose of this study is to determine new diagnostic criteria for an eye disease called keratoconus.
- Trial name
- NCT02698709
- Testing
- Analysis of anterior and posterior corneal surfaces
- Where
- Brazil
- Volunteers
- 698 people
- Sponsor
- University of Sao Paulo
Healthy Individuals, Diabetes
Heidelberg In Vivo Confocal Microscopy to Evaluate the Ocular Surface Disorders of Healthy and Diseased Individuals
In vivo confocal microscopy (IVCM) has been used in clinical settings for more than 25 years, and is noninvasive, rapid and easily repeatable technique to investigate ocular surface disorders.
- Conditions
- Healthy Individuals, Diabetes, Hypertension, Fabry Disease
- Trial name
- NCT04025801
- Where
- Taiwan
- Volunteers
- 400 people, healthy volunteers welcome
- Sponsor
- National Taiwan University Hospital
Keratoconus, Astigmatism
Corneal Epithelial and Stromal Thickness Distribution in Keratoconus
The purpose of the study was to identify corneal epithelial- and stromal-thickness distribution patterns in keratoconic eyes using spectral-domain-optical coherence tomography (SD-OCT).
- Trial name
- NCT02023619
- Where
- Norway
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- SynsLaser Kirurgi AS
Cataract, Healthy Eye
The Heidelberg Engineering ANTERION Anterior Segment Cornea and IOL Precision and Agreement Study
This is a prospective clinical study that will be conducted at one clinical site located in the United States to assess anterior segment parameters with the ANTERION
- Conditions
- Cataract, Healthy Eye, Cornea Abnormality, Post-Keratorefractive Surgery
- Trial name
- NCT04130490
- Testing
- ANTERION
- Where
- United States
- Volunteers
- 176 people, healthy volunteers welcome
- Sponsor
- Heidelberg Engineering GmbH
Healthy, Dry Eyes
Topical Menthol For Tear Secretion
Tears are the natural way to keep eyes moist, and tears are important for good vision and healthy eyes. Eyes without enought tears get dry and sore.
- Trial name
- TMTS (NCT07109609)
- Testing
- Topical application of 20% menthol solution in MCT oil.
- Where
- Canada
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Reinhold Vieth
Corneal Endothelial Cell Changes
Corneal Endothelial Cell Density Changes, When Mapracorat Ophthalmic Suspension 3%, is Administered for 14 Days
The objective of this study is to evaluate the effect on corneal endothelial cell density (cells/mm²) changes at 3 months when mapracorat ophthalmic suspension, 3% is administered QID (four times daily), for 14 days in healthy…
- Trial name
- NCT01736462
- Testing
- Mapracorat
- Where
- United States
- Volunteers
- 61 people, healthy volunteers welcome
- Sponsor
- Bausch & Lomb Incorporated
Map Dot Fingerprint Dystrophy, Post-penetrating Keratoplasty
Brillouin Microscopy Used to Evaluate Corneal Mechanical Properties
This study aims to explore the mechanical properties of the cornea using a non-invasive imaging technique called Brillouin microscopy.
- Conditions
- Map Dot Fingerprint Dystrophy, Post-penetrating Keratoplasty, Post-Descemet Membrane Endothelial Keratoplasty, Healthy Corneas
- Trial name
- NCT06914817
- Testing
- Brillouin optical scanning system (Intelon Optics) (BOSS)
- Where
- Austria
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Vienna Institute for Research in Ocular Surgery