Clinical trials: Healthy Eyes
Blindness
Enhanced Tactile Memory in the Blind
This study will determine if the brain regions in blind people that would normally be involved in vision are used instead to remember touch.
- Trial name
- NCT00076700
- Where
- United States
- Volunteers
- 45 people, healthy volunteers welcome
- Sponsor
- National Institute of Neurological Disorders and Stroke (NINDS)
TED
A Study of SCTT11 in Healthy Participants and Participants with Thyroid Eye Disease.
Multicentre, Randomized, Double-blinded, Phase I/II Clinical Study to Evaluate the Safety, Pharmacokinetics, Pharmacodynamics, and Efficacy of SCTT11 in Healthy Participants and Participants with Thyroid Eye Disease
- Trial name
- NCT06769984
- Testing
- SCTT11
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Sinocelltech Ltd.
Visual Snow Syndrome, Color Blindness
Study of Visual Perception Phenomena: Phosphene Mapping Induced by TMS and Its Relationship With Eye Movements
The purpose of this basic science study is to better understand human visual perception. Phosphenes are flashes of light that can be induced using Transcranial Magnetic Stimulation (TMS).
- Conditions
- Visual Snow Syndrome, Color Blindness, Healthy Volunteer
- Trial name
- NCT07110493
- Testing
- Transcranial Magnetic Stimulation (TMS), Electroencephalography (EEG), Eye-Tracking
- Where
- Russia
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- Skolkovo Institute of Science and Technology
WAGR Syndrome, Wilm's Tumor
Characterization of WAGR Syndrome and Other Chromosome 11 Gene Deletions
This study will explore conditions caused by the absence of certain genes on chromosome 11. These conditions include WAGR syndrome, which is characterized by a kidney tumor called Wilm s tumor, aniridia (absence of the iris of…
- Conditions
- WAGR Syndrome, Wilm's Tumor, Aniridia, Urogenital Abnormalities
- Trial name
- NCT00758108
- Where
- United States
- Volunteers
- 197 people, healthy volunteers welcome
- Sponsor
- Eunice Kennedy Shriver National Institute of Child Health and Human Development (NICHD)
Cataract, Healthy Eye
The Heidelberg Engineering ANTERION Anterior Segment Cornea and IOL Precision and Agreement Study
This is a prospective clinical study that will be conducted at one clinical site located in the United States to assess anterior segment parameters with the ANTERION
- Conditions
- Cataract, Healthy Eye, Cornea Abnormality, Post-Keratorefractive Surgery
- Trial name
- NCT04130490
- Testing
- ANTERION
- Where
- United States
- Volunteers
- 176 people, healthy volunteers welcome
- Sponsor
- Heidelberg Engineering GmbH
Healthy
Impact of Osteopathic Manipulative Treatment on Pursuit Eye Movements in Healthy Human Adults
The idea that osteopathic manipulative treatments (OMTs) should have an impact on the human visual system is not new. Nevertheless, there is a lack of scientific, objective, and experimental evidence.
- Trial name
- NCT05018390
- Testing
- Osteopathic manipulative treatment
- Where
- France
- Volunteers
- 201 people, healthy volunteers welcome
- Sponsor
- Ecole d'ostéopathie de Paris
Safety, Tolerability
Clinical Study for the Evaluation of Safety and Tolerability of PRO-172 Ophthalmic Solution+
Clinical phase I, controlled, non comparative, open, single center study evaluating the safety and tolerability of ophthalmic solution PRO-172 when applied on the ocular surface of healthy volunteers.
- Conditions
- Safety, Tolerability, Ocular Surface, Ocular Comfort
- Trial name
- PRO-172 (NCT04693429)
- Testing
- Bepotastine Besilate
- Where
- Mexico
- Volunteers
- 22 people, healthy volunteers welcome
- Sponsor
- Laboratorios Sophia S.A de C.V.
Healthy
Effect of Simvastatin Withdrawal on Ocular Endothelial Function
Statins are drugs representing the most commonly prescribed medication for the treatment of hypercholesterolemia. In a recently published study, discontinuation of statin therapy in patients after acute myocardial infarction was…
- Trial name
- NCT02533141
- Testing
- Dynamic Vessel Analyzer (DVA), Laser Doppler Velocimetry (LDV), Simvastatin
- Where
- Austria
- Volunteers
- healthy volunteers welcome
- Sponsor
- Medical University of Vienna
Eye Infections, Bacterial
Azithromycin Level in Tears and in Conjunctiva in 36 Healthy Volunteers
To evaluate azithromycin ocular conjunctiva concentrations 7 and 14 days after treatment initiation. To assess ocular and systemic tolerance/safety and azithromycin tear concentrations on Day 7
- Trial name
- NCT00356772
- Testing
- Azithromycin
- Volunteers
- healthy volunteers welcome
- Sponsor
- Laboratoires Thea
Corneal Transplant, Corneal Crosslinking
A Prospective Clinical Trial Designed to Evaluate the Repeatability and Reproducibility of the Intelon BOSS(tm) System
This is a prospective, open-label, single-site clinical trial designed to evaluate the repeatability and reproducibility of biomechanical imaging by the updated version of the BOSS device.
- Conditions
- Corneal Transplant, Corneal Crosslinking, Healthy Eyes
- Trial name
- NCT05423041
- Testing
- BOSS Imaging
- Where
- United States
- Volunteers
- 34 people, healthy volunteers welcome
- Sponsor
- Intelon Optics, Inc
Healthy
Role of Nitric Oxide in Optic Nerve Head Blood Flow Regulation During Experimental Increase of Intraocular Pressure in Healthy Humans
Autoregulation is defined as the ability of a vascular bed to adapt its vascular resistance to changes in perfusion pressure. In the eye, several studies have reported that retinal blood flow is autoregulated over a wide range of…
- Trial name
- NCT00914394
- Testing
- NG-monomethyl-L-arginine (L-NMMA), Phenylephrine, Laser Doppler Flowmetry
- Where
- Austria
- Volunteers
- 12 people, healthy volunteers welcome
- Sponsor
- Medical University of Vienna
Multiple Sclerosis, Neuromyelitis Optica Spectrum Disorders
Integrating Metabolism, Connectivity, and Mesoscale Imaging at Ultra-high Field to Decipher Mechanisms of Resilience and Neurodegeneration in Neurological Diseases and Healthy Aging
The MESO7 study is a prospective observational research project designed to investigate the mechanisms of resilience and neurodegeneration in neurological diseases and healthy aging.
- Conditions
- Multiple Sclerosis, Neuromyelitis Optica Spectrum Disorders, Myelin Oligodendrocyte Glycoprotein Antibody-Associated Disease (MOGAD), Alzheimer Disease
- Trial name
- MESO7 (NCT07202494)
- Testing
- Imaging Techniques (MRI 3T & 7T, Functional, Structural, and Metabolic Imaging)
- Where
- France
- Volunteers
- 700 people, healthy volunteers welcome
- Sponsor
- Assistance Publique Hopitaux De Marseille
Glaucoma, Intraocular Pressure
Intraocular Pressure Fluctuation in Patients With Glaucoma and in Healthy Patients During Standard Yoga Positions
The purpose of the study is to investigate the IOP difference between normal and glaucomatous eyes using standard ophthalmic tonometry devices while subjects are performing different standard yoga asanas.
- Trial name
- NCT01915680
- Where
- United States
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- Robert Ritch, MD, LLC.
Healthy, Dry Eyes
Topical Menthol For Tear Secretion
Tears are the natural way to keep eyes moist, and tears are important for good vision and healthy eyes. Eyes without enought tears get dry and sore.
- Trial name
- TMTS (NCT07109609)
- Testing
- Topical application of 20% menthol solution in MCT oil.
- Where
- Canada
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Reinhold Vieth
Blepharoptosis
A Pharmacokinetics (PK) Study in Healthy Adults
This is to characterize STN1013800 active ingredient bioavailability following multiple-dose ocular administration of STN1013800 to both eyes in healthy adults.
- Trial name
- NCT06911216
- Testing
- STN1013800 ophthalmic solution
- Where
- China
- Volunteers
- 8 people, healthy volunteers welcome
- Sponsor
- Santen Pharmaceutical Co., Ltd.
Behcet's Disease, Central Sensitisation
Assessment of Central Sensitization, Neuropathic Pain, Sleep Quality and Daily Life Activities in Behcet's Disease
There are few studies in the literature regarding increased frequency of neuropathic pain and sleep disturbance and decreased quality of life in Behçet's disease.
- Trial name
- NCT03531385
- Testing
- Central sensitisation, Neuropathic pain, Sleep disturbance
- Where
- Turkey (Türkiye)
- Volunteers
- 200 people, healthy volunteers welcome
- Sponsor
- Bursa Yuksek Ihtisas Training and Research Hospital
Brachial Plexus Injury
Changes in Optic Nerve Sheath Diameter in Response to Various Levels of End Tidal Carbon Dioxide Levels
Intracranial Pressure ( ICP ) monitoring is an essential component of traumatic brain injured ( TBI ) patients management. The clinical signs of raised ICP may be unreliable and may reflect relatively late cerebral…
- Trial name
- NCT02711774
- Testing
- ultrasonography
- Where
- India
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- All India Institute of Medical Sciences
Healthy, Idiopathic Inflammatory Myopathies
A Phase 1 Open-label Study to Evaluate Safety in Healthy Participants and Participants With Autoimmune Diseases
The purpose of this study is to determine the safety and tolerability of XmAb657 in healthy participants and participants with autoimmune diseases.
- Conditions
- Healthy, Idiopathic Inflammatory Myopathies, Systemic Sclerosis, Sjögren's Disease
- Trial name
- NCT07284797
- Testing
- XmAb657
- Where
- Australia
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Xencor, Inc.
Glaucoma, Open-Angle, Normal Tension Glaucoma
Investigation of Neurovascular Coupling in Glaucoma Patients and Healthy Subjects
Glaucoma is characterized by a progressive loss of retinal ganglion cells (RGCs) leading to optic nerve head (ONH) damage and associated visual field defects.
- Conditions
- Glaucoma, Open-Angle, Normal Tension Glaucoma, Ocular Hypertension
- Trial name
- NCT03870230
- Testing
- Fourier Domain Doppler Optical Coherence Tomography (FDOCT), Dynamic Vessel Analyzer (DVA), Pattern Electroretinography (pERG)
- Where
- Austria
- Volunteers
- 120 people, healthy volunteers welcome
- Sponsor
- Medical University of Vienna
Healthy
Vertical Stability Training Effects on the Eye-Hand Coordination of Female Volleyball Players
Purpose: Optimal eye-hand coordination is important for volleyball players. Neck disorder may affect neck function and subsequently eye-hand coordination.
- Trial name
- NCT01197430
- Testing
- exercise training
- Volunteers
- 23 people, healthy volunteers welcome
- Sponsor
- Taipei Physical Education College