Clinical trials: Healthy Humans
Overweight
The Effect of a Propionate Colon Release Form on ad Libitum Eating and Appetite Perception
The present study aims to investigate the effect of a standardized liquid breakfast containing a food grade propionate colon release form on ad libitum eating and appetite perception in healthy overweight humans using a…
- Trial name
- METABIOTIC (NCT04019951)
- Testing
- Ca-propionate 1 g, Ca-propionate 3 g
- Where
- Canada
- Volunteers
- 21 people, healthy volunteers welcome
- Sponsor
- dsm-firmenich Switzerland AG
Hepatitis C Virus
TMC435-TiDP16-C114 - A Study in Healthy Volunteers Investigating the Pharmacokinetic Interaction Between TMC435 and the Antiretroviral Agents TMC278 and Tenofovir
The purpose of this study is to investigate the effect of steady-state concentrations of TMC435 on the steady-state pharmacokinetics of TMC278 or Tenofovir , and vice versa.
- Trial name
- NCT01205139
- Testing
- TMC435, TDF, TMC435 + TDF
- Volunteers
- 48 people, healthy volunteers welcome
- Sponsor
- Tibotec Pharmaceuticals, Ireland
Healthy Subjects
Pharmacokinetic and Pharmacodynamic Effects of Insulex® R in Comparison to Humulin® R in Healthy Subjects
The goal of this clinical trial is to evaluate whether Insulex® R demonstrates similar pharmacokinetic (PK) and pharmacodynamic (PD) profiles compared to Humulin® R after a single subcutaneous dose of 0.3 units/kg in healthy…
- Trial name
- NCT07364669
- Testing
- Insulex® R (soluble human insulin, biosimilar), Humulin® R (soluble human insulin, biosimilar)
- Where
- United States
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Laboratorios Pisa S.A. de C.V.
Healthy Volunteers
A Study of [13C]Pyruvate as an Imaging Agent for Magnetic Resonance Imaging in Healthy Volunteers
The purpose of the study is to learn about the use of [13C]pyruvate as an imaging agent for MRI scans. In past studies, researchers have seen that [13C]pyruvate can improve imaging with MRI scans.
- Trial name
- NCT05041166
- Testing
- Hyperpolarized [13C] Pyruvate
- Where
- United States
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- Memorial Sloan Kettering Cancer Center
Influenza
Trial to Investigate Immune Responses Elicited by a Liquid Formulation of Influenza Virus Vaccine,(CAIV-T)
The primary objective of this study was to perform a variety of immunological assays on blood, serum, nasal wash samples, and cells obtained from healthy adult subjects for the purpose of developing assays for application in the…
- Trial name
- NCT00192231
- Testing
- CAIV-T
- Where
- Australia
- Volunteers
- 120 people, healthy volunteers welcome
- Sponsor
- MedImmune LLC
Intermittent Fasting, Healthy
Monitoring Intermittent Fasting for Human Optimization Using Wearable Technology: An N-of-1 Study
There is a growing interest in personalized health strategies, including diet, exercise, and fasting regimens, to enhance metabolic fitness.
- Conditions
- Intermittent Fasting, Healthy, Digital Health
- Trial name
- NCT06630637
- Testing
- Glucose-Ketone Index (GKI) monitoring, Continuous Glucose Monitoring (CGM), Digital dynamometer
- Where
- Singapore
- Volunteers
- 1 people, healthy volunteers welcome
- Sponsor
- Institute for Digital Medicine (WisDM)
Influenza, Human
Clinical Trial of Quadrivalent Influenza Virus Split Vaccine in Population Aged 3-8 Years
To evaluate the safety and immunogenicity of quadrivalent influenza virus split vaccine in healthy population aged 3-8 years following different immunization procedures.
- Trial name
- NCT05138705
- Testing
- Quadrivalent Influenza Virus Split Vaccine
- Where
- China
- Volunteers
- 380 people, healthy volunteers welcome
- Sponsor
- Shanghai Institute Of Biological Products
Type 2 Diabetes Mellitus
FTIH of ECC5004 in Healthy and Diabetic Participants
This is a Phase 1, randomized, double-blind, placebo-controlled, single ascending dose and multiple ascending dose study of ECC5004 in healthy participants and in patients with Type 2 Diabetes Mellitus
- Trial name
- NCT05654831
- Testing
- ECC5004
- Where
- United States
- Volunteers
- 69 people, healthy volunteers welcome
- Sponsor
- Eccogene
Infections, Papillomavirus
Safety Evaluation of a Human Papillomavirus (HPV) Vaccine in Healthy Female Control Subjects From the GSK HPV 023 Study
This phase IIIb study is designed to assess the safety of GlaxoSmithKline Biological's HPV vaccine GSK580299 in female subjects who took part in the HPV-023 (NCT00518336) study and received a placebo in the HPV-001 (NCT00689741)…
- Trial name
- NCT01418937
- Testing
- CervarixTM (GSK580299)
- Where
- 5 sites in Brazil
- Volunteers
- 164 people, healthy volunteers welcome
- Sponsor
- GlaxoSmithKline
Human Healthy Volunteers
Normative Values and Forming Regression Equations for One Minute Sit to Stand Test in Healthy Normal Indian Population
This study is to find relation between number of repetitions the volunteer able to sit and stand in an armless chair and their age, height, weight and gender.
- Trial name
- 1minSTS (NCT02218905)
- Testing
- Sit to stand test
- Where
- India
- Volunteers
- 196 people, healthy volunteers welcome
- Sponsor
- Baskaran Chandrasekaran
Effect of Food
Phase I, Open Label,Crossover Food-Effect and Absolute Bioavailability Study of WCK2349 and WCK771 in Healthy Adult Human Volunteers
This study is aimed to ascertain the effect of food on pharmacokinetics of WCK 2349 and determine the absolute bioavailability of WCK 2349 1000 mg (oral, QD dose) with respect to WCK 771 800 mg (intravenous, QD dose).
- Trial name
- NCT01875939
- Testing
- Oral WCK2349, IV WCK771
- Where
- United States
- Volunteers
- 12 people, healthy volunteers welcome
- Sponsor
- Wockhardt
Influenza
Trial to Determine the Safety and Efficacy of Influenza Virus Vaccine, Trivalent, Types A & B, Live Cold- Adapted (CAIV-T) in Healthy Children Attending Day Care Centers
The purpose of this study is to determine the efficacy of the liquid formulation of CAIVT against culture confirmed influenza illness in healthy children aged at least 6 months and less than 36 months, attending day care centers…
- Trial name
- NCT00192283
- Testing
- CAIV-T
- Where
- Finland
- Volunteers
- 2,903 people, healthy volunteers welcome
- Sponsor
- MedImmune LLC
Hyperlipidemia, Healthy
Effects of Omega-3 Fatty Acids on the Human Gene Expression
The aim of this study is to investigate the effects of short- and long-term intervention with EPA and DHA-rich fish oil on gene expression profiles in healthy and hyperlipidemic males.
- Trial name
- NCT01089231
- Testing
- Fish oil
- Where
- Germany
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Gottfried Wilhelm Leibniz Universität Hannover
Healthy Volunteers
Global Positioning Satellite and Accelerometry to Assess Human Locomotion (ACTI GPS)
The aim of the study is to validate the association of the GPS and accelerometer tools in order to assess the humain locomotion during exercises. The hypotheses are: 1.
- Trial name
- ActiGPS (NCT01805219)
- Testing
- GPS and accelerometer recording (s) during exercises
- Where
- France
- Volunteers
- 67 people, healthy volunteers welcome
- Sponsor
- University Hospital, Angers
Influenza
H7N9 Mix and Match With AS03 and MF59 in Healthy Adults
This Phase II randomized, double-blinded, controlled study in up to 1000 males and non-pregnant females, 19 to 64 years old, inclusive, who are in good health and meet all eligibility criteria is designed to provide data on an…
- Trial name
- NCT01942265
- Testing
- AS03, MF59, Influenza Virus Vaccine, Monovalent A/H7N9 A/Shanghai/2/2013
- Where
- 5 sites in United States
- Volunteers
- 980 people, healthy volunteers welcome
- Sponsor
- National Institute of Allergy and Infectious Diseases (NIAID)
Healthy Adult Participants
A First-in-Human Study to Assess the Safety, Pharmacokinetics, and Pharmacodynamics of HMB-003 in Healthy Volunteers
The purposes of this clinical study are 1. To see how the new drug (HMB-003) under study is tolerated in healthy volunteers, and if there are any important side effects. 2.
- Trial name
- NCT07798505
- Testing
- HMB-003
- Where
- United States
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Hemab ApS
Atopic Dermatitis, Psoriasis
Study in Healthy Participants and Participants With Moderate Atopic Dermatitis & Optionally, Moderate Psoriasis, and/or Mild Asthma
This Phase 1 study will investigate the safety and tolerability of EDP1867 in healthy volunteers, participants with atopic dermatitis, and, optionally, in participants with psoriasis and/or asthma.
- Conditions
- Atopic Dermatitis, Psoriasis, Asthma
- Trial name
- NCT04927195
- Testing
- EDP1867
- Where
- 7 sites in United Kingdom
- Volunteers
- 52 people, healthy volunteers welcome
- Sponsor
- Evelo Biosciences, Inc.
Bipolar Depression
A First In Human Study To Evaluate The Safety, Tolerability And Pharmacokinetics Of PF-04455242 In Single Rising Doses In Healthy Adult Volunteers
The purpose of this first in human (FIH) study is to investigate the safety, tolerability, pharmacokinetics ( how the body handles the drug) and pharmacodynamics (how the drug affects the body) of PF-04455242-01 in healthy adult…
- Trial name
- NCT00938301
- Testing
- PF-04455242
- Where
- United States
- Volunteers
- 18 people, healthy volunteers welcome
- Sponsor
- Pfizer
Human Immunodeficiency Virus (HIV) Infection
Bioequivalence Study of ADC118 Tablets in Healthy Chinese Volunteers Under Fasting Conditions
This clinical trial aims to evaluate the bioequivalence of a single oral dose of the test drug ADC118 tablets compared with the reference drugs (ACC017 tablets and emtricitabine/tenofovir alafenamide fumarate tablets [II]) under…
- Trial name
- NCT07753902
- Testing
- ACC118-Test, Reference
- Where
- China
- Volunteers
- 48 people, healthy volunteers welcome
- Sponsor
- Jiangsu Aidea Pharmaceutical Group Co., Ltd.
Alzheimer's Disease, Healthy
The Effect of Acetylcholine on Memory and Attention
This study will examine whether enhancing the chemical acetylcholine in the brain can improve memory and attention. It will identify changes in brain function that occur during these cognitive tasks.
- Trial name
- NCT00001977
- Where
- United States
- Volunteers
- 70 people, healthy volunteers welcome
- Sponsor
- National Institute of Mental Health (NIMH)
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