Clinical trials: Healthy Individuals
Tetanus, Tetanus Vaccine
Phase I/III Clinical Trial of Adsorbed Tetanus Vaccine
The study aimed to evaluate the safety and immunogenicity of an adsorbed tetanus vaccine in healthy individuals between 18 and 43 years of age.
- Trial name
- NCT07740733
- Testing
- Tetanus Toxoid (Adsorbed)
- Where
- China
- Volunteers
- 1,240 people, healthy volunteers welcome
- Sponsor
- Beijing Minhai Biotechnology Co., Ltd
Healthy, HIV
A Study of the Safety, Pharmacokinetics and Antiretroviral Activity of 10-1074
This is a phase 1 clinical trial to evaluate the safety, pharmacokinetics and the antiretroviral effects of the highly neutralizing anti-HIV-1 monoclonal antibody 10-1074 in HIV-infected and HIV-uninfected individuals.
- Trial name
- NCT02511990
- Testing
- 3 mg/kg, single dose IV administration of 10-1074, 10 mg/kg, single dose IV administration of 10-1074, 30 mg/kg, single dose IV administration of 10-1074
- Where
- 2 sites in United States, Germany
- Volunteers
- 33 people, healthy volunteers welcome
- Sponsor
- Rockefeller University
Healthy
Non-invasive Cerebellar Stimulation on Motor Learning
A crossover trial with healthy volunteers will be conducted. Six sessions will be performed once a week in a counterbalanced order and at least with seven days washout period to minimize carry-over effects.
- Trial name
- NCT02559518
- Testing
- tDCS, rTMS, pp-TMS assessment
- Where
- Brazil
- Volunteers
- 18 people, healthy volunteers welcome
- Sponsor
- Universidade Federal de Pernambuco
Hyperkyphosis, Viscoelasticity
Viscous Elastic Properties of Superficial Back Muscles in Individuals With Hyperkyphosis
Thoracic hyperkyphosis is a common spinal deformity that may alter the biomechanical and viscoelastic properties of trunk muscles.
- Trial name
- NCT07441213
- Where
- Turkey (Türkiye)
- Volunteers
- 88 people, healthy volunteers welcome
- Sponsor
- Sanko University
Healthy Individuals With Hamstring Tightness
The Immediate Effects Of Thoracolumbar Fascia Inhibition And Suboccipital Muscle Inhibition
This randomized controlled trial aimed to compare the immediate effects of two self-myofascial release techniques-suboccipital muscle inhibition and thoracolumbal fascia inhibition-on hamstring flexibility, spinal range of…
- Trial name
- NCT07096076
- Testing
- Thoracolumbar fascia inhibition, Suboccipital inhibition group, hamstring stretching
- Where
- Turkey (Türkiye)
- Volunteers
- 75 people, healthy volunteers welcome
- Sponsor
- Bulent Ecevit University
Peripheral Oxygen Saturation, Healthy Individuals
INVESTIGATION OF PERIPHERAL OXYGEN SATURATION VALUES MEASURED IN DIFFERENT BODY POSITIONS AND FINGERS IN HEALTHY YOUNG ADULT INDIVIDUALS
This study aims to examine peripheral oxygen saturation values measured in different body positions and fingers in healthy young adult individuals. The research was planned in a quasi-experimental design.
- Trial name
- NCT06591403
- Testing
- the index and middle fingers of each participant's active hand
- Where
- Turkey (Türkiye)
- Volunteers
- 200 people, healthy volunteers welcome
- Sponsor
- Uludag University
Alzheimer Disease, Inactivity
The Link Between Physical Activity and Brain Health in Healthy Adults
The goal of this observational study is to investigate the cross-sectional relationship between physical activity and brain health from a multiscale approach (neuropsychology, neuroimaging, peripheral biomarkers and genetics) in…
- Conditions
- Alzheimer Disease, Inactivity, Preventive Therapy
- Trial name
- MINA (NCT07025070)
- Where
- Spain
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Technical University of Madrid
Healthy Young Men
Effect of Acute Grape Seed Extract Supplementation on the Heart Rate Recovery in Young Individuals
This study hypothesized that sustained sympathoexcitation via MMA slows down PHRR and that GSE supplementation is effective at improving PHRR in young individuals.
- Trial name
- NCT07137988
- Testing
- 600 mg grape seed extract, 600 mg Starch
- Where
- United States
- Volunteers
- 12 people, healthy volunteers welcome
- Sponsor
- California Baptist University
Healthy Individuals, At Least 21 Years of Age
Noninvasive Blood Ethanol Measurement With Infrared Spectroscopy
The objective of this study is to assess the performance of a noninvasive device for the detection of blood alcohol levels.
- Trial name
- NCT01168102
- Where
- United States
- Volunteers
- 500 people, healthy volunteers welcome
- Sponsor
- InLight Solutions
Traumatic Brain Injury
Effects of Exercise on Memory in Healthy and Brain-Injured Individuals
Background: Research has shown that one exercise session may improve a person s ability to recall information they learned before the exercise.
- Trial name
- NCT01939769
- Testing
- Exercise - Low-intensity exercise, Exercise - High-intensity exercise
- Where
- United States
- Volunteers
- 42 people, healthy volunteers welcome
- Sponsor
- National Institute of Neurological Disorders and Stroke (NINDS)
Neck Pain, Headache
Cervical Spine Manipulation Affects on Balance and Proprioception
Cervical spine manipulation (CSM) is utilized by many health care practitioners in the management of patients with neck pain and headache.
- Trial name
- NCT01745705
- Testing
- Cervical Spine Manipulation, Manual Contact
- Where
- United States
- Volunteers
- 45 people, healthy volunteers welcome
- Sponsor
- University of Nevada, Las Vegas
Staphylococcus (S.) Aureus Infection
Staphylococcus Aureus Caught in Action at the Site of Infection
This study is to obtain a comprehensive view of S. aureus adaptations in the infected human host and (i) to improve the understanding of the interface between antibiotic therapy, resistance development and virulence factor…
- Trial name
- PROSA (NCT04781569)
- Testing
- data collection, blood draw, nose swabs
- Where
- Switzerland
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- University Hospital, Basel, Switzerland
Covid-19
Effects of Face Masks on Cardiopulmonary Capacity in Healthy Individuals
The aim of our study is to compare the effects of face masks on cardiopulmonary capacity in young healthy individuals. The results of our study will show the effects of face masks commonly used during the pandemic period.
- Trial name
- NCT04785781
- Testing
- without masks, Surgical face mask (Vheal Med Co., Ltd., Istanbul, Turkey), FFP2\N95 protective face mask (Musk protective technology, Gaziantep, Turkey)
- Where
- Turkey (Türkiye)
- Volunteers
- 16 people, healthy volunteers welcome
- Sponsor
- Pamukkale University
SARS-CoV-2 Infection, COVID-19
Study to Describe the Safety, Tolerability, Immunogenicity, and Efficacy of RNA Vaccine Candidates Against COVID-19 in Healthy Individuals
This is a Phase 1/2/3, randomized, placebo-controlled, observer-blind, dose-finding, vaccine candidate-selection, and efficacy study in healthy individuals.
- Trial name
- NCT04368728
- Testing
- BNT162b1, BNT162b2, BNT162b2SA
- Where
- 175 sites in United States, Argentina and 4 more
- Volunteers
- 46,969 people, healthy volunteers welcome
- Sponsor
- BioNTech SE
Healthy Volunteers, Heart Failure
A Research Study on the Effects of NNC0537-1482 in Healthy Individuals When Injected Under the Skin
The study is testing a new medicine to potentially treat people with heart failure. The main purpose of the study is to see if the new study medicine is safe and how it works in the body.
- Trial name
- NCT06625307
- Testing
- NNC0537-1482
- Where
- Netherlands
- Volunteers
- 31 people, healthy volunteers welcome
- Sponsor
- Novo Nordisk A/S
Healthy
Investigation of the Genetic and Environmental Determinants of MP Including Response to Supplementation
This study aims to investigate genetic and environmental determinants of macular pigment (MP) and assess the effects of lutein and zeaxanthin-rich supplements on macular pigment levels.
- Trial name
- NCT01778231
- Testing
- Nutrof Total
- Where
- United Kingdom
- Volunteers
- 56 people, healthy volunteers welcome
- Sponsor
- Queen's University, Belfast
Healthy Individuals
Effects of Exercises Combined With Blood Flow Restriction in Healthy Individuals
Purpose of the study is; to investigate the effect of exercises combined with blood flow restriction on strength, proprioception and functional motor performance in healthy individuals.
- Trial name
- NCT03401567
- Testing
- Exercise group
- Where
- Turkey (Türkiye)
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Dokuz Eylul University
Aging
A Study to Evaluate Efficacy of Dietary Ingredient in Vitality and Metabolic Factors in Healthy Individuals
The present study is a randomized, placebo-controlled, feasibility study to evaluate efficacy of dietary ingredients in vitality \& metabolic factors in healthy individuals.
- Trial name
- NCT06188949
- Testing
- Dolichos biflorus (Horsegram) seed extract, Carica papaya leaves extract
- Where
- 2 sites in India
- Volunteers
- 35 people, healthy volunteers welcome
- Sponsor
- Vedic Lifesciences Pvt. Ltd.
Healthy Volunteers (HV)
Examining the Effects of Reformer Pilates Exercises on Physical Fitness and Cognitive Functions in Healthy Individuals
Pilates is an exercise method that aims to increase body awareness and improve physical fitness through controlled movements based on mind-body integration.
- Trial name
- NCT07134517
- Testing
- Pilates exercise
- Volunteers
- 42 people, healthy volunteers welcome
- Sponsor
- Inonu University
Nerve Block, Anesthesia, Local
Cutaneous Anesthesia of the Lateral Femoral Cutaneous Nerve
The purpose of this study is to investigate and describe the anatomical differences in distribution of the blocked area following a perineural LFCN (Lateral Femoris Cutaneous Nerve) block with either 8 ml or 16 ml of Ropivacaine…
- Conditions
- Nerve Block, Anesthesia, Local, Pain, Postoperative, Anatomical Distribution
- Trial name
- NCT03138668
- Testing
- Ropivacaine Injection
- Where
- Denmark
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- Zealand University Hospital