Clinical trials: Healthy Individuals, open to volunteers
Healthy
Effect of Intermittent Hypoxia in Healthy Individuals
The use of acute intermittent hypoxia (AIH) has been examined in animal and human studies to gain an understanding of its effect on spinal excitability and synaptic strength.
- Trial name
- NCT04691518
- Testing
- Acute Intermittent Hypoxia
- Where
- United States
- Volunteers
- 32 people, healthy volunteers welcome
- Sponsor
- Shirley Ryan AbilityLab
Bronchiectasis Adult, Healthy Controls Group - Age and Sex-matched
Cardiopulmonary Responses to 6-Minute Stepper Test in Bronchiectasis Versus Healthy Controls
Individuals with bronchiectasis exhibit productive cough and recurrent lung infections as well as reduced exercise capacity, physical activity level, and respiratory and peripheral muscle strength.
- Trial name
- NCT06631261
- Testing
- No intervention; Observational study
- Where
- Turkey (Türkiye)
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Hacettepe University
Stroke Patients
Relationship Between Respiratory Muscle Strength, Balance, Trunk Control, Functional Capacity in Stroke Patients
The purpose of this study; To determine the relationship between respiratory muscle strength, balance, trunk control, functional capacity and motor functions in stroke patients and compare them with healthy individuals.
- Trial name
- NCT06259877
- Where
- Turkey (Türkiye)
- Volunteers
- 44 people, healthy volunteers welcome
- Sponsor
- Kırıkkale University
Healthy, Healthy Adult
Assessment of Lung Function (Lufu) at Sea Level LA vs. High Altitude HA in Healthy Individuals
To study the effect of a re-ascent to high altitude (Quito Ecuador: 2850m) after a one-week stay at sea level (after prior descent from 2850m) on lung function and pulmonary resistance/reactance in healthy individuals, who live…
- Conditions
- Healthy, Healthy Adult, High Altitude Effects, High Altitude
- Trial name
- NCT07804537
- Testing
- Re-ascent from sea level to 2850m
- Where
- Switzerland
- Volunteers
- 14 people, healthy volunteers welcome
- Sponsor
- Silvia Ulrich Somaini
Imagery (Psychotherapy), Postural Control
The Effect of Motor Image Training on Balance Performance in Geriatric Individuals
The goal of this study [type of study: clinical trial] is to was planned to investigate the effect of motor imagery training given to geriatric individuals with action observation on their balance performance and to compare these…
- Conditions
- Imagery (Psychotherapy), Postural Control, Postural Balance, Virtual Reality Therapy
- Trial name
- NCT06056180
- Testing
- Balance Training, Motor İmagery Training, Action Observation Training
- Where
- Turkey (Türkiye)
- Volunteers
- 46 people
- Sponsor
- Muğla Sıtkı Koçman University
Hypoxia, Hypoxia Brain
Study of the Effects of Acute Exposure to Moderate Altitude Hypoxia on Prospective Memory.
The goal of this study is to investigate whether prospective memory, i.e., memory for delayed intentions, is impaired at moderate altitude (4,000m).
- Conditions
- Hypoxia, Hypoxia Brain, Hypoxia Altitude Simulation Test, Hypoxia in Healthy Individuals
- Trial name
- HYPRO (NCT07585227)
- Testing
- Hypoxia exposure, Oxygen administration, Air administration
- Where
- France
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- Direction Centrale du Service de Santé des Armées
Hypertension, Autonomic Dysfunction
Autonomic Regulation of Blood Pressure and Heart Rate During Orthostasis and Exercise in Healthy and Hypertensive Individuals
The goal of this observational study is to assess arterial stiffness and autonomic regulation of blood pressure and heart rate in healthy adults and people with arterial hypertension during orthostatic stress and graded physical…
- Conditions
- Hypertension, Autonomic Dysfunction, Orthostatic Hypotension
- Trial name
- NCT07482462
- Where
- Slovenia
- Volunteers
- 120 people, healthy volunteers welcome
- Sponsor
- University Medical Centre Ljubljana
Otherwise Healthy Individuals With Systolic Blood Pressure (SBP) From 110 to 139 mmHg and Low-density Lipoprotein Cholesterol (LDL-C) ≥ 100 mg/dL
A Study to Evaluate COR-2003 as Monotherapy and Co-Administered With COR-1004 in Adult Volunteers
This clinical trial has two parts. In Part A, the goal is to learn about the safety and tolerability of COR-2003 when it is given alone.
- Trial name
- NCT07858019
- Testing
- COR-2003, COR-1004 + COR-2003
- Where
- 2 sites in Australia, New Zealand
- Volunteers
- 108 people, healthy volunteers welcome
- Sponsor
- Corsera Health
Healthy Adult
Exploring Pain Modulation With TMS and Repeated Pain Conditioning in Healthy Individuals
Conditioned pain modulation (CPM) is the behavioral measure of diffuse noxious inhibitory control (DNIC), an endogenous pain inhibitory pathway in which pain inhibits pain.
- Trial name
- NCT06726018
- Testing
- Conditioned Pain Modulation (CPM)
- Where
- United States
- Volunteers
- 75 people, healthy volunteers welcome
- Sponsor
- Priyanka Rana, PT, MPT, PhD
Relatively Healthy Volunteers
Daily Intake of Multivitamin & Mineral Supplementation Effects on Biological Age of Relatively Healthy Middle-aged Individuals
Micronutrients, such as vitamins and minerals, are required to sustain fundamental physiological processes in individuals. As individuals age, the risk of having suboptimal levels of micronutrients increases due to several…
- Trial name
- CEDIRA (NCT06666660)
- Testing
- Multivitamin/Mineral supplements
- Where
- 2 sites in Singapore
- Volunteers
- 400 people, healthy volunteers welcome
- Sponsor
- National University of Singapore
Alzheimer Disease, Inactivity
The Link Between Physical Activity and Brain Health in Healthy Adults
The goal of this observational study is to investigate the cross-sectional relationship between physical activity and brain health from a multiscale approach (neuropsychology, neuroimaging, peripheral biomarkers and genetics) in…
- Conditions
- Alzheimer Disease, Inactivity, Preventive Therapy
- Trial name
- MINA (NCT07025070)
- Where
- Spain
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Technical University of Madrid
High Altitude, Healthy
Assessment of Total Pulmonary Resistance sPAP/CO Between Sea Level LA vs. High Altitude HA After Re-ascent in Healthy Individuals
To study the effect of a re-ascent after a one-week stay at sea level (after prior descent from 2850m) to high altitude (Quito Ecuador: 2850m) on pulmonary resistance (sPAP/CO) and other hemodynamic outcomes in healthy…
- Conditions
- High Altitude, Healthy, Healthy Adult, High Altitude Effects
- Trial name
- NCT07804589
- Testing
- Re-Ascent from sea level to 2850m
- Where
- Switzerland
- Volunteers
- 14 people, healthy volunteers welcome
- Sponsor
- Silvia Ulrich Somaini
Herpes Zoster (HZ)
A Study to Evaluate the Safety of Recombinant Herpes Zoster Vaccine for Healthy Individuals
The purpose of this clinical study is to evaluate the safety and immunogenicity of receiving two doses of recombinant herpes zoster vaccine (CHO cells) (RHZV) in healthy individuals aged 40 years and above.
- Trial name
- NCT06932523
- Testing
- Recombinant herpes zoster vaccine with low-dose adjuvant, Recombinant herpes zoster vaccine with high-dose adjuvant, Low-dose adjuvant
- Where
- China
- Volunteers
- 645 people, healthy volunteers welcome
- Sponsor
- Shanghai Institute Of Biological Products
Sound Exposure, Exercise Performance
Effect of High-Level Headphone Sound Exposure on Exercise Responses in Young Healthy Individuals
This study will investigate the effect of high-level headphone sound exposure on cardiorespiratory responses and perceived exertion during a submaximal treadmill exercise test in young healthy individuals.
- Trial name
- NCT07556666
- Testing
- High-Level Headphone Sound Exposure, No-Sound Headphone Condition
- Volunteers
- 38 people, healthy volunteers welcome
- Sponsor
- Saglik Bilimleri Universitesi
Mild Cognitive Impairment
CBD for Individuals at Risk for Alzheimer's Disease
This is a double-blind, randomized controlled trial designed to test the effects of cannabidiol (CBD) on validated biomarkers of Alzheimer's disease (AD) progression, and behavioral, neurocognitive, and clinical measures, with…
- Trial name
- NCT05822362
- Testing
- Cannabidiol
- Where
- United States
- Volunteers
- 236 people
- Sponsor
- University of Colorado, Denver
Isolated Gastrocnemius Tightness, Healthy Adult Participants
Isolated Gastrocnemius Tightness and Tactile Sensitivity
Isolated gastrocnemius tightness is associated with various foot pathologies, particularly metatarsalgia and hallux valgus, and is also commonly observed in the general population.
- Trial name
- NCT07828392
- Testing
- Ankle Dorsiflexion Index
- Where
- Turkey (Türkiye)
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Nigde Omer Halisdemir University
Health Personnel
Respiratory Virome Diversity and Baseline Immunity in Healthy Individuals in Shanghai
This study investigates the diversity of the respiratory virome in healthy individuals in Shanghai and its interaction with the host's baseline immune response.
- Trial name
- NCT06641856
- Testing
- Sample Collection
- Where
- China
- Volunteers
- 300 people, healthy volunteers welcome
- Sponsor
- Ruijin Hospital
Longevity, Quality of Life
Effectiveness of Microdosed GLP-1 in Improving Health, Quality of Life, and Longevity Measures
The goal of this clinical study has two objectives. The Primary Objective is to evaluate the effectiveness of microdosed GLP-1 receptor agonists in improving measures of health, quality of life, and longevity.
- Conditions
- Longevity, Quality of Life, Mood, Inflammation
- Trial name
- NCT07092605
- Testing
- GLP-1
- Where
- United States
- Volunteers
- 150 people, healthy volunteers welcome
- Sponsor
- AgelessRx
Healthy Individuals (Controls), Vascular Surgery Patients With Acute Thrombosis
Haemodialysis Alters Hypercoagulability of Blood in Dialysis Patients
Primary Objective: To develop a thrombotic event risk assessment model integrating serum biomarkers (TM, TAT, t-PAIC, PIC) with clinical data, systematically compare its predictive performance across healthy populations, vascular…
- Conditions
- Healthy Individuals (Controls), Vascular Surgery Patients With Acute Thrombosis, Dialysis Patients
- Trial name
- TAT-t-PAIC (NCT07098676)
- Where
- China
- Volunteers
- 900 people, healthy volunteers welcome
- Sponsor
- Ai Peng
Multiple Sclerosis
This Study Involves a Positron Emission Tomography (PET) Scan Using a New Investigational Radioactive Tracer, [18F]-FZTA, to Detect Inflammation in the Brain. The Tracer Will be Tested in Healthy Younger Adults and Individuals With Multiple Sclerosis.
This study involves a Positron Emission Tomography (PET) scan using a new investigational radioactive tracer, [18F]-FZTA, to detect inflammation in the brain.
- Trial name
- FZTA Pilot (NCT07115017)
- Testing
- [18F] FZTA
- Where
- United States
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- Washington University School of Medicine