Clinical trials: Healthy Individuals.
Feeding Behaviors, Lack of Satiety
Metabolic and Neurofunctional Responses to Breakfasts
This study aims at assessing the effects of glucose and different types of breakfast on metabolic and neurofunctional responses in healthy individuals.
- Conditions
- Feeding Behaviors, Lack of Satiety, Attention Deficit and Disruptive Behavior Disorders
- Trial name
- NCT02897570
- Testing
- Glucose, Milk & Cereals, Milk, apple & snack
- Where
- Italy
- Volunteers
- 12 people, healthy volunteers welcome
- Sponsor
- Ospedale San Donato
Sepsis, Septic Shock
IL-40 and IL-41 Levels in Sepsis, Septic Shock, and Healthy Individuals
This study aims to investigate the blood levels of two recently identified immune-related proteins, Interleukin-40 (IL-40) and Interleukin-41 (IL-41), in patients with sepsis and its more severe form, septic shock.
- Conditions
- Sepsis, Septic Shock, Inflammation, Biomarkers
- Trial name
- NCT06963541
- Testing
- No intervention; Observational study
- Where
- Turkey (Türkiye)
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- Melahat Yalcin Solak
Fibromyalgia
Fecal Microbiome Transplantation From Healthy Donors to Individuals With Fibromyalgia
This study aims to investigate if a fecal microbiome transplantation (FMT) from healthy donors can reduce symptoms of fibromyalgia, a condition causing chronic pain that is difficult to treat and diagnose.
- Trial name
- FM-FMT-RCT (NCT06424041)
- Testing
- Fecal Microbiome Transplantation
- Where
- Israel
- Volunteers
- 100 people
- Sponsor
- Rambam Health Care Campus
Low HDL Cholesterol
Association Between HDL Functions and Atherosclerotic Burden in Healthy Individuals
This is a study of HDL function in healthy individuals classified in three groups according to their HDL-cholesterol levels (Low HDL-C, Intermediate HDl-C and High HDL-C), with the purpose of investigating which characteristics…
- Trial name
- NCT02106013
- Where
- Brazil
- Volunteers
- 101 people, healthy volunteers welcome
- Sponsor
- University of Campinas, Brazil
Healthy
(18)F-FDG PET Database of Adult Healthy Individuals
Epilepsy is the most common chronic neurological disorder in the world, affecting more than 50 million people worldwide. Approximately 35% of patients with epilepsy are refractory to all available antiepileptic drugs.
- Trial name
- BDD-FDG (NCT03100227)
- Testing
- PET [18F] FDG, Anatomical MRI
- Where
- France
- Volunteers
- 41 people, healthy volunteers welcome
- Sponsor
- Hospices Civils de Lyon
Obesity, Overweight
Predicting Adherence to a Heart-Healthy Diet in Lean and Obese Individuals
Background: Sticking to a diet plan can be difficult, but is important for many different health reasons. Some people seem to have a harder time following and sticking to a diet plan than others.
- Trial name
- NCT01862796
- Testing
- Underfeeding diet, Weight maintaining diet
- Where
- United States
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)
Healthy Volunteers Only
Effects of Substance P on Headache Induction in Healthy Individuals
Substance P is a signaling molecule that has been implicated in the pathogenesis of headache. This study aims to ascertain whether administration of substance P can induce headache in healthy adults.
- Trial name
- NCT06632080
- Testing
- Substance P
- Where
- Denmark
- Volunteers
- 21 people, healthy volunteers welcome
- Sponsor
- Danish Headache Center
Healthy Adult Participants, Gut Microbiomes
DORA - A Study Using Digital Health Tools/Platform to Explore the Impact of the Consumption of Senior Milk Powder Containing Synbiotics on the Gut micRobiome in Healthy Aging Individuals
The DORA study is a single-arm, open-label, interventional exploratory study designed to evaluate the impact of a synbiotic-containing senior milk powder on the gut microbiome and selected biological, physiological, and digital…
- Conditions
- Healthy Adult Participants, Gut Microbiomes, AI
- Trial name
- DORA (NCT07575529)
- Testing
- Synbiotic Nutritional Product
- Where
- Singapore
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Danone Asia Pacific Holdings Pte, Ltd.
Arterial Stiffness, Blood Pressure
Korean Red Ginseng Rg3 Extract on Arterial Stiffness and Blood Pressure
The purpose of the study is to evaluate the acute effect of a standardized extract of KRG (Rg3-KRG) consisting of 30% total ginsenosides, including 10% Rg3 ginsenoside on arterial stiffness and blood pressure, as measured by the…
- Trial name
- KRAB (NCT01951443)
- Testing
- Ginseng, Wheat Bran
- Where
- Canada
- Volunteers
- 24 people, healthy volunteers welcome
- Sponsor
- Unity Health Toronto
Healthy Men and Women
Absorption, Metabolism and Excretion of Artichoke Polyphenols in Healthy Individuals
A number of studies have reported the presence of polyphenolic compounds in artichokes, being the most abundant the caffeoylquinic acids (CQAs), which are esters between quinic acid and the hydroxycinnamate caffeic acid.
- Trial name
- NCT04095949
- Testing
- Artichokes
- Where
- United Kingdom
- Volunteers
- 8 people, healthy volunteers welcome
- Sponsor
- King's College London
Healthy
Effect of Intermittent Hypoxia in Healthy Individuals
The use of acute intermittent hypoxia (AIH) has been examined in animal and human studies to gain an understanding of its effect on spinal excitability and synaptic strength.
- Trial name
- NCT04691518
- Testing
- Acute Intermittent Hypoxia
- Where
- United States
- Volunteers
- 32 people, healthy volunteers welcome
- Sponsor
- Shirley Ryan AbilityLab
Generalized Adult Periodontitis
Serological Evaluation of 77A/G and 11A/12A Gene of MMP-13 in Periodontitis Affected and Healthy Individuals
50 periodontitis 50 healthy individuals serological evaluation will done to see association of 77A/G AND 11A/12A gene polymorphisms of MMP-13
- Trial name
- SEGPPAH (NCT02423304)
- Testing
- blood samples collected from all patients
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Panineeya Mahavidyalaya Institute of Dental Sciences & Research Centre
Healthy, Stress
A Clinical Trial to Assess the Effect of AP-Brain Collagen Peptides on the Improvement of Attention, Focus, and Memory in Stressed But Otherwise Healthy Individuals
The goal of this clinical trial is to learn about the effects of AP-Brain collagen peptide on attention, focus, and memory in adults who are stressed but otherwise healthy.
- Trial name
- NCT07572240
- Testing
- AP-Brain Collagen Peptide
- Where
- 8 sites in India
- Volunteers
- 72 people, healthy volunteers welcome
- Sponsor
- Rousselot BVBA
Type 2 Diabetes, Diabetes
The Effects of Anti-Inflammatory Treatment on Insulin Resistance in Healthy Volunteers
This study, conducted at the Phoenix Indian Medical Center, Phoenix, Arizona, will determine whether reducing subclinical inflammation lessens insulin resistance in healthy, obese volunteers.
- Trial name
- NCT00339833
- Testing
- Salsalate
- Where
- United States
- Volunteers
- 54 people
- Sponsor
- National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)
Fatigue, Mental Alertness
A Study to Evaluate the Effect of EnXtra® and EnXtra® + Caffeine on Mental Alertness and Fatigue in Healthy Individuals
Acute Stage: The present study is a randomized, double-blind, placebo-controlled, single-dose, 4-way, cross-over, study. Approximately not more than 170 individuals will be screened and considering a screening failure rate of…
- Trial name
- NCT06560008
- Testing
- EnXtra® (300 mg) + Caffeine (200 mg)
- Where
- 3 sites in India
- Volunteers
- 128 people, healthy volunteers welcome
- Sponsor
- Vedic Lifesciences Pvt. Ltd.
Type 2 Diabetes, Healhty
Insulin-Mediated Glucose Uptake and Organ Perfusion Assessed by Total-Body PET During GIP and GLP-1 Infusion
This study investigates how the naturally occurring gut hormones GIP and GLP-1 influence whole-body glucose uptake and organ perfusion in humans.
- Trial name
- NCT07398300
- Testing
- GIP, GLP-1, Saline (0.9% Sodium Chloride)
- Where
- Denmark
- Volunteers
- 36 people, healthy volunteers welcome
- Sponsor
- Copenhagen University Hospital, Rigshospitalet
Depressive Disorder, Major, Persistent Depressive Disorder
Effectiveness of an Ecological Momentary Emotion Regulation Intervention
This two-armed randomized controlled trial aims to investigate the effectiveness of an emotion regulation intervention in individuals with and without depressive disorders.
- Conditions
- Depressive Disorder, Major, Persistent Depressive Disorder, Healthy
- Trial name
- NCT06311136
- Testing
- Valence-Specific Ecological Momentary Intervention
- Where
- Germany
- Volunteers
- 200 people, healthy volunteers welcome
- Sponsor
- Heidelberg University
Healthy
Effects of Exercise Training with Blood Flow Restriction
In this study, it was aimed to compare the effects of low load blood flow restriction exercise (LL-BFRE) training versus high load resistance exercise (HL-RE) training in healthy young individuals on the parameters of lower…
- Trial name
- NCT06507501
- Testing
- Low Load Blood Flow Restriction Exercise Training (LL-BFRE), High Load Resistive Exercise Training (HL-RE)
- Where
- Turkey (Türkiye)
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Atlas University
Depression, Stress
Effects of Landscapes on the Brain
There is an established consensus between researchers that the contact with natural environments has beneficial influence on mental health and well-being of people exposed to them.
- Conditions
- Depression, Stress, Anxiety Disorders
- Trial name
- NCT04210856
- Testing
- Contemplative landscape exposure
- Where
- Singapore
- Volunteers
- 95 people, healthy volunteers welcome
- Sponsor
- National University of Singapore
Manipulation, Psychologic, Pain
Manipulation and Myofascial Techniques On Sacroiliac Joint Dysfunction
Aimed to compare the effects of High-Velocity Low-Amplitude (HVLA) manipulation and myofascial release techniques on performance in healthy individuals with sacroiliac joint dysfunction.
- Conditions
- Manipulation, Psychologic, Pain, Performance Anxiety, Participation, Patient
- Trial name
- HVLA (NCT06089772)
- Testing
- Comparing to Manipulation and Myofascial Release Techniques
- Where
- Turkey (Türkiye)
- Volunteers
- 56 people, healthy volunteers welcome
- Sponsor
- Alanya Alaaddin Keykubat University