Clinical trials: Healthy Individuals.
Dental Plaque
Effect of Enzymes on Dental Biofilm Accumulation in Healthy Individuals
The purpose of the study is to assess the effect of enzyme containing lozenges on dental plaque accumulation in healthy adults.
- Trial name
- NCT05082103
- Testing
- Enzyme lozenge 1, Enzyme lozenge 2
- Where
- Denmark
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- Novozymes A/S
Functional Constipation
Study of NGM282 in Subjects With Functional Constipation and Healthy Individuals
The purpose of this study is to determine the effect of NGM282 on colonic transit, bile acid homeostasis, and fecal fat in subjects with functional constipation and healthy individuals.
- Trial name
- NCT02649062
- Testing
- NGM282
- Where
- United States
- Volunteers
- 31 people, healthy volunteers welcome
- Sponsor
- NGM Biopharmaceuticals, Inc
Healthy
Comparability of Keratometry of VERION Image Guided System With Established Measuring Devices
The purpose of this study is to determine if the keratometric functions of the VERION Image Guided System are comparable to those of established keratometric devices (IOLMaster 500, Pentacam HR, LenStar LS900).
- Trial name
- NCT02377154
- Testing
- Slit lamp, Autorefractor, IOLMaster 500
- Where
- Germany
- Volunteers
- 150 people, healthy volunteers welcome
- Sponsor
- Heidelberg University
Borderline Personality Disorder
Assessment of Sense of Identity in Patients Diagnosed With Borderline Personality Disorder. A Pilot Study
One of the key features and long considered a fundamental element of Borderline Personality Disorder is the disruption of identity.
- Trial name
- MASB (NCT04948905)
- Testing
- Evaluation using the Self-Defining Memory Questionnaire
- Where
- France
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Centre Hospitalier Universitaire de Nīmes
Digestive Health, Metabolic Health
Investigating the Tolerability of Oat Fiber (BG-OS) in Healthy Individuals
The goal of this interventional study is to evaluate the tolerability and potential health benefits of oat fiber oligosaccharide (BG-OS) in healthy adults aged 18-70 years.
- Trial name
- NCT06739941
- Testing
- Oat fiber (BG-OS)
- Where
- United States
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- One Bio Inc.
Chronic Obstructive Pulmonary Disease, Healthy
Ventilation Distribution in COPD Patients During Breathing Exercises
ELTGOL (Slow Expiration with the Opened Glottis in the Lateral posture) is an airway clearance technique performed in the lateral decubitus position.
- Trial name
- NCT06381973
- Testing
- ELTGOL_Physio, ELTGOL_Auto, PEP
- Where
- Belgium
- Volunteers
- 33 people, healthy volunteers welcome
- Sponsor
- William Poncin, PT, PhD
Healthy
Investigating the Acute Effects of Blueberry (Poly)Phenols on Vascular Function and Cognition in Healthy Individuals.
This study aims to determine the effect of blueberry (poly)phenol vs placebo on vascular function and cognitive performance with an insight into cerebral blood flow velocity changes, across all ages of the general healthy…
- Trial name
- BluLife (NCT03592966)
- Testing
- Wild Blueberry Powder
- Where
- United Kingdom
- Volunteers
- 92 people, healthy volunteers welcome
- Sponsor
- King's College London
Healthy
Observational Metabolic Health Study
The rationale for this study is to observe the effect of a consumer-grade commercially available product called Mimio Biomimetic Cell Care on metabolic health in overweight individuals.
- Trial name
- NCT06790407
- Testing
- Mimio Study Product
- Where
- United States
- Volunteers
- 96 people, healthy volunteers welcome
- Sponsor
- Mimio Health, Inc.
Young, Healthy
Videofluoroscopic of Deglutition Study of the Initiation of Pharyngeal Phase in Young Adults
This study has as objective to characterize the start of pharyngeal phase of swallowing, in the various food consistencies and volumes, with and without the influence of verbal orders, observed on videofluoroscopy of deglutition.
- Trial name
- VFD-IPP (NCT01120587)
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Fortaleza University
Healthy Lifestyle, Health Behavior
Effects of Online Pilates and Face-To-Face Pilates on Healthy Individuals
Many studies on pilates have shown that these exercises positively affect the endurance of core muscles, mental health, and quality of life in healthy individuals when applied face-to-face.
- Trial name
- COVID (NCT05309486)
- Testing
- Online and Face-to-face Pilates trainings
- Where
- Turkey (Türkiye)
- Volunteers
- 58 people, healthy volunteers welcome
- Sponsor
- Ankara Medipol University
Healthy Individuals With no Periodontal Disease
The Effect of Nitrate Supplementation on Tongue Microbiome
The objective of this study is to investigate how the host environment influences microbiome structure. Specifically, the spatial organization of nitrate-metabolizing bacteria that will flourish in high and low salivary nitrate…
- Trial name
- NCT07865481
- Testing
- Nitrate-Supplemented Beet Juice, Nitrate-Depleted Beet Juice
- Where
- United States
- Volunteers
- 24 people, healthy volunteers welcome
- Sponsor
- The Forsyth Institute
Stroke
Group Lifestyle Balance™ for Individuals With Stroke (GLB-CVA)
The purpose of this RCT is to examine the efficacy of the Group Lifestyle Balance (GLB) program adapted for people with stroke (CVA) on primary (weight) and secondary outcomes at 3, 6, 12 months from enrollment into the program.
- Trial name
- GLB-CVA (NCT03873467)
- Testing
- Group Lifestyle Balance, Usual Care
- Where
- United States
- Volunteers
- 65 people
- Sponsor
- Baylor Research Institute
Mild Cognitive Impairment, Mild Dementia
Gait, cOgnitiOn & Decline (GOOD)
The main objective of the GOOD initiative was to determine which spatio-temporal gait parameters and/or combination(s) of spatio-temporal gait parameters best differentiate between cognitively healthy individuals (CHI), patients…
- Conditions
- Mild Cognitive Impairment, Mild Dementia, Moderate Dementia, Healthy
- Trial name
- NCT02350270
- Testing
- gait and cognitive testing
- Where
- France
- Volunteers
- 2,800 people, healthy volunteers welcome
- Sponsor
- University Hospital, Angers
Anterior Cruciate Ligament Reconstruction Rehabilitation
Effects of Core Exercises on Balance in People With and Without ACL Surgery
The main purpose of this study is to evaluate and compare the effects of an 8-week core stabilization exercise program on balance, trunk muscle endurance, and lower body strength.
- Trial name
- NCT07328139
- Testing
- Core Stabilization Exercise Program
- Where
- Turkey (Türkiye)
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Biruni University
Supplement, Resistance Training Adaptation
Skeletal Muscle Adaptations to Peptide-Supplemented Resistance Exercise Training
Skeletal muscle size, an important metabolic tissue, is governed by the balance between two opposing processes, muscle protein synthesis and muscle protein breakdown.
- Trial name
- NCT07773142
- Testing
- Resistance Exercise Training with or without daily supplementation, Dual Energy X-Ray Absorptiometry (DEXA) Scan, Muscle Sampling
- Where
- United Kingdom
- Volunteers
- 24 people, healthy volunteers welcome
- Sponsor
- University of Birmingham
Idiopathic Pulmonary Fibrosis, Healthy
Determining in Vitro Properties of Epithelial Cells From Individuals With Genetic Variants Associated With Idiopathic Pulmonary Fibrosis
The investigators are trying to understand the role of specific genes in the function of airway surface cells. The investigators know that there are some common genetic markers that are associated with various lung diseases.
- Trial name
- NCT02187393
- Where
- United States
- Volunteers
- healthy volunteers welcome
- Sponsor
- University of Colorado, Denver
Healthy Individuals, Patients With Diabetes.
Retinal Function in Relation to Transient or Chronic Challenges to Retinal Metabolism
The aim of the study is to investigate how the retina adapts to different metabolic challenges, e.g. chronic systemic hypoxia, hyperglycemia, special training conditions or diets as well as transient changes in the content of…
- Trial name
- NCT01721811
- Testing
- Hyperoxia, Glucose
- Where
- Denmark
- Volunteers
- 120 people, healthy volunteers welcome
- Sponsor
- Glostrup University Hospital, Copenhagen
Glycemic Level
Effect of Adrenaline (1:80,000) Containing Local Anesthesia on Glycemic Level of Diabetic and Healthy Individuals Undergoing Tooth Extraction
Dental extraction is one of the most frequently performed surgical interventions worldwide, and local anaesthesia remains its pharmacological foundation.The addition of adrenaline (epinephrine) 1:80 000 to lignocaine 2 % is…
- Trial name
- NCT07633106
- Testing
- Local anesthesia with 1:80000 adrenaline
- Where
- Pakistan
- Volunteers
- 90 people, healthy volunteers welcome
- Sponsor
- Dow University of Health Sciences
Asthma, Dietary Intervention
Vegan Diet and Immune-Inflammatory Outcomes in Asthma and Healthy Adults
This randomized controlled study evaluates the effects of a balanced vegan diet compared with a balanced omnivorous diet on inflammatory and immune response markers and clinical asthma parameters in healthy adults and individuals…
- Conditions
- Asthma, Dietary Intervention, Vegan Diet
- Trial name
- VEGASTHMA (NCT07480369)
- Testing
- Omnivorous diet, Vegan diet
- Volunteers
- 280 people, healthy volunteers welcome
- Sponsor
- Medical University of Gdansk
Balance Postural, Pain
Informational Manual Therapy to Improve Standing Balance
Objectives: The aim of this study is to assess the effect of Informational Manual Therapy (IMT) on quiet standing and quality of life in healthy individuals.
- Conditions
- Balance Postural, Pain, Quality of Life
- Trial name
- NCT04404829
- Testing
- Manual Therapy
- Where
- Spain
- Volunteers
- 57 people, healthy volunteers welcome
- Sponsor
- Universitat Internacional de Catalunya