Clinical trials: Healthy Individuals.
Parkinson Disease, Gaucher Disease
Detecting Dopaminergic Deficits in Individuals At-risk for Parkinsonism
The purpose of this study is to determine if participants have changes in dopamine cells in their brain using DaTSCAN™ brain imaging.
- Conditions
- Parkinson Disease, Gaucher Disease, Idiopathic Rapid Eye Movement Sleep Disorder
- Trial name
- NCT01358474
- Where
- United States
- Volunteers
- 56 people, healthy volunteers welcome
- Sponsor
- University of Minnesota
Healthy Participants
COVID-19 Study Assessing the Efficacy and Safety of Anti-Spike SARS CoV-2 Monoclonal Antibodies for Prevention of SARS CoV-2 Infection Asymptomatic in Healthy Adults and Adolescents Who Are Household Contacts to an Individual With a Positive SARS-CoV-2 RT-PCR Assay
Primary Objectives: Cohort A: To evaluate the efficacy of REGN10933+REGN10987 compared to placebo in preventing symptomatic SARS-CoV-2 infection (broad-term) confirmed by RT-qPCR Cohort A and Cohort A1: To evaluate the safety and…
- Trial name
- NCT04452318
- Testing
- REGN10933 + REGN10987
- Where
- 134 sites in United States, Moldova and 1 more
- Volunteers
- 3,303 people, healthy volunteers welcome
- Sponsor
- Regeneron Pharmaceuticals
Parkinson's Disease, Parkinsonian Syndrome
A Study of Neurophysiologic Changes in Individuals With Parkinson's Disease
The goal of this study is to investigate neurophysiologic tests that have the potential of serving as screening tools for Parkinson's disease.
- Trial name
- NCT00117195
- Testing
- Automated Neuropsychological Assessment Matrix
- Where
- United States
- Volunteers
- 620 people, healthy volunteers welcome
- Sponsor
- Institute for Neurodegenerative Disorders
Real tDCS, Sham tDCS
Supporting Decisions With Transcranial Direct Current Stimulation in Healthy Young and Elderly Individuals
Decisions are part of the daily life. On the neuronal level, activity in the dorsolateral prefrontal cortex (dlPFC) is important during complex decisions (e.g., whether something is emotional for a person or not).
- Trial name
- NCT03959462
- Testing
- real anodal transcranial direct current stimulation
- Where
- Switzerland
- Volunteers
- 254 people, healthy volunteers welcome
- Sponsor
- University of Bern
Healthy, Alcohol Drinking
Rimonabant to Reduce Alcohol Consumption
This study will examine whether Rimonabant, a drug that blocks cannabinoid-1 (CB1) receptors in the brain, affects alcohol consumption.
- Trial name
- NCT00075205
- Testing
- SR141716 (Rimonabant)
- Where
- United States
- Volunteers
- 54 people
- Sponsor
- National Institute on Alcohol Abuse and Alcoholism (NIAAA)
Potential Abnormality of Glucose Tolerance, Appetitive Behavior
Acute Effects of Fruit Juices Consumption on Postprandial Glycemic Responses and Satiety
This study investigated the acute effects of two fruit juices on postprandial glycemic responses and satiety in healthy individuals
- Trial name
- NCT06163937
- Testing
- Glucose as reference food, Orange juice, Mixed fruit juice
- Where
- 2 sites in Greece
- Volunteers
- 10 people, healthy volunteers welcome
- Sponsor
- Agricultural University of Athens
Healthy, Omega 3
Observing Metabolism of EPA With Consideration of Genetics And Sex
The goal of this clinical study is to learn how fast EPA is converted to other molecules, including DHA, with consideration of biological sex and genetics in healthy humans.
- Conditions
- Healthy, Omega 3, Metabolism, Lipids
- Trial name
- OMEGA (NCT06975241)
- Testing
- EPA 2.4g/day
- Where
- Canada
- Volunteers
- 64 people, healthy volunteers welcome
- Sponsor
- University of Toronto
Low Level Laser Therapy, Performance
Photobiomodulation in Different Doses on Strength Capacities and Functional Performance
Background: Photobiomodulation has been explored for years, with wide clinical use for wound healing and analgesia in varied orthopedic conditions, but the number of research and clinical use has increased during the last decade.
- Conditions
- Low Level Laser Therapy, Performance, Sport
- Trial name
- NCT03860766
- Testing
- Photobiomodulation
- Where
- Brazil
- Volunteers
- 56 people, healthy volunteers welcome
- Sponsor
- University of Sao Paulo
Cancer, Breast Cancer
Investigation of a Digital Healthy Habits Program for Individuals With Breast Cancer
This mixed methods study will involve obtaining user feedback on the first 4 weeks of the Healthy Habits for Cancer (HCC) Program.
- Conditions
- Cancer, Breast Cancer, Obesity, Overweight and Obesity
- Trial name
- NCT04967209
- Where
- United States
- Volunteers
- 30 people
- Sponsor
- Noom Inc.
Scapholunate Interosseous Ligament Injury, Scaphoid-Lunate Instability
Comparison of Strength, Weight Bearing, Proprioception, Reaction Time and Function in Scapholunate Instability
Scapholunate (SL) instability is the most common type of instability seen in the wrist, resulting from SLI injury or excessive mobility [1,2].
- Conditions
- Scapholunate Interosseous Ligament Injury, Scaphoid-Lunate Instability, Scapholunate Dissociation
- Trial name
- NCT07134452
- Testing
- Baseline Assessments
- Where
- Turkey (Türkiye)
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Hacettepe University
Sedentary Behavior
Impact of 4 Months of Exercise Changes of Heart Health-related Epigenetic Markers in Healthy, Sedentary Individuals
We aim to analyze the impact of a single acute exercise intervention (ergometry) on the expression pattern of specific heart health related miRNAs in healthy, previously sedentary participants, and how this pattern will be…
- Trial name
- miR-4-heart (NCT04791306)
- Testing
- supervised exercise training, home-based exercise training
- Where
- Austria
- Volunteers
- 46 people, healthy volunteers welcome
- Sponsor
- Paracelsus Medical University
Inborn Errors of Metabolism, Epilepsy (Treatment Refractory)
Metabolites in Blood and Breath in Metabolic Conditions
In patients with inborn errors of metabolism (IEM) and in those requiring a ketogenic diet for the treatment of medical conditions, relevant biochemical analytes are routinely and regularly measured in venous or capillary blood…
- Trial name
- NCT07704606
- Testing
- Observational Study
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- University Children's Hospital, Zurich
Chronic Low Back Pain (CLBP), Heart Rate Variability
Autonomic Differences in Heart Rate Variability Between Healthy and Chronic Low Back Pain Subjects
This study aims to evaluate the autonomic differences in heart rate variability (HRV) between healthy individuals and those with chronic low back pain.
- Conditions
- Chronic Low Back Pain (CLBP), Heart Rate Variability, Autonomic Nervous System Dysfunction
- Trial name
- NCT06760390
- Where
- Spain
- Volunteers
- 98 people, healthy volunteers welcome
- Sponsor
- Universidad de Extremadura
Panic Disorder, Healthy
Neurobehavioral Correlates of Caffeine on Anxiety, Avoidance and Interoception in Healthy Individuals and Panic Disorder.
The current study is a placebo-controlled, double-blind, randomized controlled study using a cross-over design, including Healthy Controls (HC) and participants with Panic Disorder (PD).
- Trial name
- BINCAP (NCT06145490)
- Testing
- Caffeine
- Where
- 2 sites in Sweden
- Volunteers
- 42 people, healthy volunteers welcome
- Sponsor
- Uppsala University
Healthy, Chronic Ankle Instability, CAI
Relationship Between Muscle Strength and Balance
This study aims to examine the relationship between lower extremity muscle strength and balance and to compare these parameters between healthy individuals and individuals with lower extremity injuries.
- Conditions
- Healthy, Chronic Ankle Instability, CAI, Anterior Cruciate Ligament Injury, Muscle Strengh
- Trial name
- NCT07419750
- Where
- Turkey (Türkiye)
- Volunteers
- 72 people, healthy volunteers welcome
- Sponsor
- Biruni University
Dry Eye Syndromes, Age-Related Macular Degeneration
Efficacy of OmegaBoost to Increase Omega-3 Levels in Healthy Individuals
The purpose of this study is to determine increases in the Omega Index test indicating optimal Omega-3s particularly eicosapentaenoic acid (EPA) and docosahexaenoic acid (DHA) levels for overall systemic benefits including…
- Conditions
- Dry Eye Syndromes, Age-Related Macular Degeneration, Omega 3 Index
- Trial name
- NCT05763940
- Testing
- OmegaBoost, Nature Made (soft gel), Nature Made (gummy)
- Where
- United States
- Volunteers
- 130 people, healthy volunteers welcome
- Sponsor
- Western University of Health Sciences
Cardiovascular Health
Evaluate Efficacy of Oxyjun on Cardiovascular Health in Healthy Individuals.
Terminalia arjuna, commonly known as arjuna, that belongs to the family of Combretaceae. Most clinical and experimental studies for Terminalia arjuna, have suggested that the crude drug possesses anti-ischemic, antioxidant…
- Trial name
- NCT04715126
- Testing
- Oxyjun
- Where
- 4 sites in India
- Volunteers
- 81 people, healthy volunteers welcome
- Sponsor
- Vedic Lifesciences Pvt. Ltd.
Healthy Eating Index, Muscle Strain
Evaluation of the Relationship Between Healthy Eating and Intrinsic Capacity in Elderly Individuals
The aim of this study is to evaluate the relationship between intrinsic capacity and healthy eating in elderly individuals.
- Conditions
- Healthy Eating Index, Muscle Strain, Frailty
- Trial name
- NCT05335343
- Testing
- no intervention
- Where
- Turkey (Türkiye)
- Volunteers
- 200 people
- Sponsor
- Sultan Abdulhamid Han Training and Research Hospital, Istanbul, Turkey
Healthy Individuals
Assessment of Temperature by Infrared Thermography and Blood Conduction Velocity by Doppler After Applying Shortwave Diathermy and Microwave - Correlations With Cardiovascular and Hemodynamic Parameters
The deep heat therapies are increasingly frequent in daily physical therapist for the treatment of musculoskeletal diseases. The use of such procedures is justified by their analgesic, anti-inflammatory, antiespasmolíticos and…
- Trial name
- NCT01872117
- Testing
- Shortwave therapy, Microwave therapy
- Where
- Brazil
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- University of Sao Paulo
Breast Cancer
The Perspective of Healthy Individuals on Breast Cancer Risk Prediction Report In The Indonesian Population
In 2016, a meta-analysis showed that DNA-based risk reporting alone does not facilitate behavior change. However, there have been several studies showing that tailoring care plans related to diet may help with adherence to a…
- Trial name
- PERCEPTION (NCT05562440)
- Testing
- Focus Group Discussion
- Where
- Indonesia
- Volunteers
- 10 people, healthy volunteers welcome
- Sponsor
- Nalagenetics Pte Ltd