Clinical trials: Healthy Japanese Adult Male
Healthy
A Study of JNJ-40411813 in Healthy Japanese Male Participants
The purpose of this study is to evaluate the safety, tolerability, and pharmacokinetics (PK) after single dose and multiple dose administrations of JNJ-40411813 in Japanese healthy adult male participants.
- Trial name
- NCT04677530
- Testing
- JNJ-40411813
- Where
- Japan
- Volunteers
- 39 people, healthy volunteers welcome
- Sponsor
- Janssen Pharmaceutical K.K.
Healthy Male
Study of Aldafermin (NGM282) in Healthy Adult Male Japanese and Non-Japanese Subjects
This is an open-label study to assess safety, tolerability, and pharmacokinetics of Aldafermin (NGM282) in healthy adult male Japanese and non-Japanese subjects
- Trial name
- NCT04828265
- Testing
- Aldafermin
- Where
- United States
- Volunteers
- 36 people, healthy volunteers welcome
- Sponsor
- NGM Biopharmaceuticals, Inc
Japanese Healthy Adult Male
A Bioequivalence (BE) Study of TAK-438 Orally Disintegrating (OD) Tablet
The purpose of this study is to evaluate the BE of single oral dose of TAK-438 OD 20 milligram (mg) tablet without water and TAK-438 20 mg tablet with water (Study 1), and TAK-438 OD 20 mg tablet with water and TAK-438 20 mg…
- Trial name
- NCT03808493
- Testing
- TAK-438 OD, TAK-438
- Where
- Japan
- Volunteers
- 48 people, healthy volunteers welcome
- Sponsor
- Takeda
Healthy
A Phase 1 Study of Single-dose Subcutaneous E6011 in Japanese Healthy Adult Male Subjects
This study (Protocol No. E6011-J081-002) is a single-center, randomized, double-blind, placebo-controlled, single ascending dose (SAD) study to evaluate mainly the safety and tolerability of a single subcutaneous administration…
- Trial name
- NCT02146261
- Testing
- E6011
- Where
- Japan
- Volunteers
- 32 people, healthy volunteers welcome
- Sponsor
- Eisai Co., Ltd.
Japanese Healthy Adult Males
Drug-Drug Interaction Study Between TAK-272 and Itraconazole, Digoxin or Midazolam
The purpose of this study is to evaluate the effect of repeated-dose administration of itraconazole on the pharmacokinetics of TAK-272, as well as the effect of repeated-dose administration of TAK-272 on the pharmacokinetics of…
- Trial name
- NCT02370615
- Testing
- TAK-272, Digoxin, Itraconazole
- Where
- Japan
- Volunteers
- 34 people, healthy volunteers welcome
- Sponsor
- Takeda
Healthy Volunteer
Bioequivalence Study Evaluating the Pharmacokinetics of DMB-3111 and Trastuzumab in Healthy Japanese Male Adults
This study is a randomized Trastuzumab-controlled double-blind parallel-group study.
- Trial name
- NCT02100917
- Testing
- DMB-3111, trastuzumab
- Where
- Japan
- Volunteers
- 70 people, healthy volunteers welcome
- Sponsor
- Meiji Seika Pharma Co., Ltd.
Japanese Healthy Adult Male Participants
Phase 1 TAK-906 Single and Multiple Ascending Dose Study in Japanese Healthy Male Participants
The purpose of this study is to evaluate safety, tolerability, pharmacokinetics, and pharmacodynamics of single and multiple oral doses of TAK-906 in Japanese healthy male participants.
- Trial name
- NCT03237156
- Testing
- TAK-906
- Where
- Japan
- Volunteers
- 24 people, healthy volunteers welcome
- Sponsor
- Takeda
Hyperphosphatemia
Bioequivalence Study of BAY77-1931 Granule
The study is conducted as a randomized, non-blinded, 2-way crossover study. Target population is 60 Japanese healthy male adult subjects selected by screening examination which will be conducted within 4 weeks before the first…
- Trial name
- NCT01053676
- Testing
- Lanthanum Carbonate (Fosrenol, BAY77-1931) Granule, Lanthanum Carbonate (Fosrenol, BAY77-1931) Chewable tablet
- Where
- Japan
- Volunteers
- 59 people, healthy volunteers welcome
- Sponsor
- Bayer
Healthy
A Study to Investigate the Safety, Tolerability, and Pharmacokinetics of JNJ-39439335 in Healthy Japanese and Caucasian Adult Male Participants
The purpose of this study is to investigate the safety, tolerability, and pharmacokinetics of JNJ-39439335 in healthy Japanese and Caucasian adult male participants in Part 1, and in healthy Japanese adult male participants in…
- Trial name
- NCT01631487
- Testing
- JNJ-39439335 10 mg, JNJ-39439335 25 mg, JNJ-39439335 50 mg
- Where
- United States
- Volunteers
- 86 people, healthy volunteers welcome
- Sponsor
- Janssen Research & Development, LLC
Healthy Male Adults, Food Effect in Healthy Volunteers
A Study to Evaluate the Effect of Food on the Bioavailability of AJ201, and Safety, Tolerability, and Pharmacokinetics of AJ201 in Japanese and White Healthy Male Participants
This is a Phase 1, randomized, single-dose, open-label, two-way crossover study to evaluate the effect of food on AJ201, and to evaluate the safety, tolerability, and pharmacokinetics of AJ201 in Japanese and White healthy male…
- Trial name
- NCT07549919
- Testing
- AJ201
- Where
- United States
- Volunteers
- 26 people, healthy volunteers welcome
- Sponsor
- AnnJi Pharmaceutical Co., Ltd.
Healthy
A Pharmacokinetic Study to Assess the Effect of Food in Healthy Male Participants Receiving TMC435
The purpose of this study is to investigate the effect of food on the pharmacokinetics (explores what the body does to the drug) and safety of TMC435 in Japanese healthy adult male participants.
- Trial name
- NCT01799603
- Testing
- TMC435
- Where
- Japan
- Volunteers
- 24 people, healthy volunteers welcome
- Sponsor
- Janssen Research & Development, LLC
Healthy Volunteers
Single Ascending Dose of ASP3772 Study in Japanese Healthy Male and Female Adults, and Single Ascending Dose Study of ASP3772 in Comparison With PPSV23 in Japanese Elderly Male and Female Subjects
The purpose of this study is to evaluate the safety and tolerability of 3 different dose levels of ASP3772 administered subcutaneously or intramuscularly to Japanese healthy adults 20 to 49 years of age.
- Trial name
- NCT04265911
- Testing
- ASP3772 (subcutaneous), ASP3772 (intramuscular), PPSV23 (subcutaneous)
- Where
- Japan
- Volunteers
- 126 people, healthy volunteers welcome
- Sponsor
- Affinivax, Inc.
Japanese Healthy Male Adult Volunteers
E2022 Patch Formulation Single Dose Phase I Study
The purpose of this study is to evaluate the pharmacokinetics of a single dose of E2022 in healthy Japanese male volunteers.
- Trial name
- NCT01253434
- Testing
- E2022
- Where
- Japan
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- Eisai Co., Ltd.
Healthy Japanese Adult Male
A Phase 1, Single and Multiple Dose Study of TAK-137
The purpose of this study is to assess the safety, tolerability and pharmacokinetics of TAK-137 in healthy male subjects.
- Trial name
- NCT02322606
- Where
- Japan
- Volunteers
- healthy volunteers welcome
- Sponsor
- Takeda
Healthy Volunteers
Study to Evaluate the Safety, Tolerability, and Pharmacokinetics of ASP5354 in Healthy Adult Japanese Male Participants
The purpose of this study is to evaluate the safety, tolerability, and pharmacokinetics of single intravenous doses of ASP5354 in healthy, adult Japanese male participants.
- Trial name
- NCT04878471
- Testing
- Pudexacianinium chloride
- Where
- Japan
- Volunteers
- 12 people, healthy volunteers welcome
- Sponsor
- Astellas Pharma Inc
Healthy Adult
A Bioequivalence Study Comparing Improved Versus Current Orally Disintegrating E2020 10 mg Tablet in Healthy Japanese Adult Males
The purpose of this study is to investigate the bioequivalence of improved and current orally disintegrating E2020 10 mg tablets as a single dose in Japanese healthy adult males for each of two administration methods…
- Trial name
- NCT01506752
- Testing
- Donepezil Hydrochloride
- Where
- Japan
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- Eisai Co., Ltd.
Rheumatoid Arthritis
A Single Ascending Dose Study to Characterize the Pharmacokinetics, Safety, and Tolerability of SAR441566 in Healthy Adult Japanese Male Participants.
This is a cross-over, Phase 1, 3-treatment period single sequence study. The purpose of this study is to characterize pharmacokinetics (PK), safety, and tolerability of single ascending oral doses of SAR441566 in healthy male…
- Trial name
- NCT05858788
- Testing
- SAR441566
- Where
- United States
- Volunteers
- 10 people, healthy volunteers welcome
- Sponsor
- Sanofi
Healthy
Safety, Tolerability and Pharmacokinetics of SAR231893 (REGN668) in Healthy Japanese Adult Male Subjects
Primary Objective: Assess the safety and tolerability of SAR231893 (REGN668) after ascending single subcutaneous (SC) doses in healthy Japanese adult male subjects Secondary Objectives: Assess the following parameters after…
- Trial name
- NCT01537653
- Testing
- SAR231893 (REGN668)
- Where
- Japan
- Volunteers
- 32 people, healthy volunteers welcome
- Sponsor
- Sanofi
Healthy Male Volunteer
A Study of the Safety and Pharmacokinetics of JNJ-38518168 in Japanese and Caucasian Male Participants and the Effect of JNJ-38518168 on the Blood Levels of Midazolam
The purpose of Part 1 of this study is to evaluate the safety, tolerability, and pharmacokinetics ("PK", how the drug is absorbed in the body, distributed within the body, and how it is removed from the body over time) of…
- Trial name
- NCT01442532
- Testing
- JNJ-38518168 (30 mg), JNJ-38518168 (10 mg), JNJ-38518168 (3 mg)
- Where
- United States
- Volunteers
- 94 people, healthy volunteers welcome
- Sponsor
- Janssen Research & Development, LLC
Healthy
A Single-Dose Pharmacokinetics and Safety Study of TMC278 in Healthy Adult Japanese Participants
The purpose of this study is to evaluate the pharmacokinetics and safety of TMC278 after a single oral dose of TMC278 25 mg tablet (27.5 mg as the hydrochloride salt) under fed conditions in healthy Japanese adult male…
- Trial name
- NCT01804244
- Testing
- TMC278
- Where
- Japan
- Volunteers
- 8 people, healthy volunteers welcome
- Sponsor
- Janssen Pharmaceutical K.K.