Clinical trials: Healthy Male Adults
Healthy
Lesinurad Tablet Bioequivalence
This study will assess the bioequivalence of lesinurad tablets manufactured at two different sites.
- Trial name
- NCT02127775
- Testing
- Lesinurad 400 mg (manufactured at Site 1), Lesinurad 400 mg (manufactured at Site 2)
- Where
- United States
- Volunteers
- 54 people, healthy volunteers welcome
- Sponsor
- Ardea Biosciences, Inc.
Prostatic Neoplasms
A Drug-Drug Interaction Study of Diltiazem and MK-5684 in Healthy Adult Male Participants (MK-5684-011)
Researchers have designed a study medicine called MK-5684 as a new way to treat prostate cancer. The purpose of this study is to learn what happens to MK-5684 in a person's body over time (a pharmacokinetic or PK study).
- Trial name
- NCT06554639
- Testing
- MK-5684, Prednisone, Fludrocortisone acetate
- Where
- United States
- Volunteers
- 12 people, healthy volunteers welcome
- Sponsor
- Merck Sharp & Dohme LLC
Anesthesia, Sedation
A Study Evaluating the Mass Balance of Micro-dose[14C]HSK3486 Emulsion Injection in Healthy Adults
This study is designed to evaluate the mass balance in healthy Chinese male subjects after receiving a single dose of intravenous [14C]HSK3486, so as to assess the overall pharmacokinetics and safety of HSK3486 in humans and…
- Trial name
- NCT03751969
- Testing
- HSK3486
- Volunteers
- healthy volunteers welcome
- Sponsor
- Sichuan Haisco Pharmaceutical Group Co., Ltd
Adult ALL
Single and Multiple Ascending Dose Study With EP395
This is a study to asses the safety and tolerability of single and multiple ascending doses of EP395, administered by oral capsules, in healthy subjects with the aim to determine the safe dose range of EP395 for further clinical…
- Trial name
- NCT04819854
- Testing
- EP395
- Where
- United Kingdom
- Volunteers
- 78 people, healthy volunteers welcome
- Sponsor
- EpiEndo Pharmaceuticals
Drug-drug Interaction
Drug-Drug Interaction Study of HBI-3000 and Paroxetine in Healthy Adult Male and Female Subjects
Drug-Drug Interaction Study of HBI-3000 and Paroxetine in Healthy Adult Male and Female Subjects
- Trial name
- NCT04650542
- Testing
- HBI-3000, Paroxetine
- Where
- 2 sites in United States, Australia
- Volunteers
- 39 people, healthy volunteers welcome
- Sponsor
- HUYABIO International, LLC.
Healthy Adult Males, Healthy Subjects
Comparing The Effect of Proprioceptive Neuromuscular Facilitation (PNF) When Coupled With Dry Needling (DN), Acupuncture (AN) or Sham Needling (SN) on Knee Range of Motion (ROM), Jump Height and Unipedal Balance
Muscle tightness was found to increase injury risks. Muscle relaese techniques and needling were known to reduce muscle tightness, their specific influence on functional muscle performance remains inconclusive.
- Trial name
- NCT07612969
- Testing
- Proprioceptive Neuromuscular Facilitation with Dry Needling, Proprioceptive Neuromuscular Facilitation with Acupuncture, Proprioceptive Neuromuscular Facilitation
- Where
- Lebanon
- Volunteers
- 65 people
- Sponsor
- Mohamad Karam
Healthy Male and Female Subjects
A Comparative Bioavailability Study of Reformulated Ibuprofen 2% and 4% Oral Suspensions (Berlin Chemie AG) and Versus Ibuprofen (Nurofen®) 200 mg/5 ml Oral Suspension
Purpose of the study is to compare three different formulations of Ibuprofen oral suspension (liquid taken by mouth) to see if there are any differences in how much of the active substance and how quickly it was taken up by by…
- Trial name
- NCT07036861
- Testing
- Ibuprofen 2%, Ibuprofen 4%
- Where
- 2 sites in Lithuania
- Volunteers
- 74 people, healthy volunteers welcome
- Sponsor
- Berlin-Chemie AG Menarini Group
Urinary Incontinence, Mobility Impairment
Feasibility Study of an Individualized Exergame Training for Older Adults With MI and/or UI (VITAAL)
This study examines the feasibility of an individualized video game training (VITAAL Exergame) for older adults with mobility impairments and/or urinary incontinence.
- Conditions
- Urinary Incontinence, Mobility Impairment, Older Adults
- Trial name
- NCT04587895
- Testing
- VITAAL Exergame, Conventional Training UI, Conventional Training MI
- Where
- Switzerland
- Volunteers
- 40 people
- Sponsor
- Eling DeBruin
Healthy Adult Male, Healthy Adult Females
Examining Olive Oil Extract on Knee Comfort and Function
The goal of this study is to learn if an olive oil extract works to improve knee pain and discomfort in adults. The main questions it aims to answer are: 1) Does the olive oil extract improve the perceptions of knee pain and…
- Conditions
- Healthy Adult Male, Healthy Adult Females, Joint Discomfort
- Trial name
- NCT07514013
- Testing
- Olive Oil Extract
- Where
- United States
- Volunteers
- 168 people, healthy volunteers welcome
- Sponsor
- Applied Food Sciences Inc.
Healthy
Drug-drug Interaction Study of FYU-981 and Oxaprozin
This is an open-label, 2-period add-on study to assess the drug-drug interaction between FYU-981 and oxaprozin. The purpose of this study is to investigate the pharmacokinetics of each period in a single administration of FYU-981…
- Trial name
- NCT03350386
- Testing
- FYU-981, Oxaprozin
- Where
- Japan
- Volunteers
- 12 people, healthy volunteers welcome
- Sponsor
- Mochida Pharmaceutical Company, Ltd.
Healthy Volunteers
The Study is Designed to Evaluate Single Ascending Doses of AR882 in Healthy Adult Males
A randomized, double-blind, placebo-controlled, single ascending dose study of AR882 in healthy adult males.
- Trial name
- NCT04347005
- Testing
- Cohort 1: AR882, Cohort 2: AR882, Cohort 3: AR882
- Where
- Australia
- Volunteers
- 64 people, healthy volunteers welcome
- Sponsor
- Arthrosi Therapeutics
Diabetic Foot
BE STUDY OF METFORMIN GSK 1000mg
A randomized, balanced, open label, crossover, two period, two treatment, two sequence, single dose, oral bioequivalence study under fasting condition.
- Trial name
- BA/BE 199/11 (NCT01710553)
- Testing
- Glucophage 1000mg, Metformin GSK 1000mg
- Volunteers
- 32 people, healthy volunteers welcome
- Sponsor
- GlaxoSmithKline
Healthy Adult Male
Bioequivalence Study of Brexpiprazole Orally Disintegrating Tablets (ODT) 2mg
To investigate the bioequivalence of brexpiprazole ODT 2 mg and brexpiprazole conventional tablet 2 mg
- Trial name
- NCT03902574
- Testing
- Brexpiprazole ODT 2mg with water, Brexpiprazole ODT 2mg without water, Brexpiprazole conventional tablet 2mg
- Where
- Japan
- Volunteers
- 21 people, healthy volunteers welcome
- Sponsor
- Otsuka Pharmaceutical Co., Ltd.
Lactose Intolerance
Effect of a Standard Meal on the Pharmacokinetic Profile of RP-G28 in Healthy Adult Male and Female Subjects
Randomized, open-label, 2-period, 2-sequence, crossover study to evaluate the effect of a standard meal on the pharmacokinetic (PK) profile of orally administered RP-G28.
- Trial name
- RP (NCT03563846)
- Testing
- RP-G28
- Where
- United States
- Volunteers
- 14 people, healthy volunteers welcome
- Sponsor
- Ritter Pharmaceuticals, Inc.
Healthy Male Volunteers
Open-label Study to Assess the Absorption, Metabolism, Excretion, and Mass Balance of a Single Oral Dose of [14C]-20 mg/100 μCi Anaprazole Sodium Enteric-coated Capsule in Healthy Adult Male Subjects
This is an open-label, single-dose, absorption, metabolism, excretion, and mass balance study following a single oral dose of [14C]-20 mg/100 μCi Anaprazole Sodium enteric-coated capsule in healthy adult male subjects.
- Trial name
- NCT04476394
- Testing
- [14C]-Anaprazole Sodium enteric-coated capsule
- Volunteers
- 6 people, healthy volunteers welcome
- Sponsor
- Sihuan Pharmaceutical Holdings Group Ltd.
Healthy
Bioequivalence Study of Pantoprazole Sodium 40 mg Delayed Release Tablets Fasting Study
This study was to compare the single-dose oral bioequivalence of Pantoprazole sodium 40 mg delayed release tablets (containing 45.1 mg of Pantoprazole sodium sesquihydrate equivalent to 40 mg of Pantoprazole) of OHM Laboratories…
- Trial name
- NCT01654705
- Testing
- Pantoprazole
- Where
- India
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- Ranbaxy Laboratories Limited
Healthy Adult Males
Non- Essential Amino Acid Requirements and Metabolism in Humans
Protein is a major structural component of all cells in the body. The nutritional importance of protein is because of their amino acids.
- Trial name
- NCT02009917
- Where
- Canada
- Volunteers
- 6 people, healthy volunteers welcome
- Sponsor
- University of British Columbia
Healthy Volunteers Bioavailability Study
Fasting Bioavailability Study of Mylan's Revefenacin Inhalation Solution
Single-Dose Fasting Bioavailability Study of Revefenacin Inhalation Solution, 175 mcg/3 mL in 24 Healthy Chinese Adult Male and Female Volunteers.
- Trial name
- NCT05207111
- Testing
- Revefenacin Inhalation Solution
- Where
- China
- Volunteers
- 24 people, healthy volunteers welcome
- Sponsor
- Mylan Pharma UK Ltd.
Healthy Volunteer
Human Mass Balance and Biotransformation Study of [14C]Afuresertib
This study adopts a single-center, single-dose, non-randomized, open-label design with a proposed enrollment of 6-10 healthy male subjects.
- Trial name
- NCT05489744
- Testing
- [14C]Afuresertib
- Where
- China
- Volunteers
- 6 people, healthy volunteers welcome
- Sponsor
- Laekna Limited
Normal Healthy Volunteers
Safety Tolerability and Pharmacokinetics of Oral NIM-1324 in Healthy Adult Male and Female Volunteers
This is a randomized, double-blind, placebo-controlled, ascending dose, multi-cohort study. The primary objective of this study is to assess the safety and tolerability of single and 7-day repeat oral doses NIM-1324 in healthy…
- Trial name
- NCT05019950
- Testing
- NIM-1324
- Where
- Australia
- Volunteers
- 56 people, healthy volunteers welcome
- Sponsor
- NImmune Biopharma