Clinical trials: Healthy Men
Healthy
A Study in Healthy Men to Test How BI 730357 is Processed by the Body
The main objectives of the study are as follows: To assess the mass balance recovery of (C-14) BI 730357-radioactivity (also expressed as 14C-BI 730357-EQ) in urine and faeces after a single oral dose of 50 mg BI 730357 base (BS)…
- Trial name
- NCT03664011
- Testing
- BI 730357 mixed with [C-14]BI 730357 BS
- Where
- Netherlands
- Volunteers
- 6 people, healthy volunteers welcome
- Sponsor
- Boehringer Ingelheim
Healthy
A Study in Healthy Men to Test How Different Doses of BI 1595043 Are Tolerated
The main objectives of this trial are to investigate safety, tolerability and pharmacokinetics (PK) of BI 1595043 in healthy male subjects following oral administration of single rising doses.
- Trial name
- NCT04439838
- Testing
- BI 1595043
- Where
- Belgium
- Volunteers
- 64 people, healthy volunteers welcome
- Sponsor
- Boehringer Ingelheim
Healthy, Postmenopausal
AZD1981 Bioavailability Study of Intravenous (IV) and Oral Formulations
The primary objective is to investigate the pharmacokinetics of AZD1981 given in different formulations and to measure renal clearance
- Conditions
- Healthy, Postmenopausal, Surgically Sterile Women
- Trial name
- NCT00918398
- Testing
- AZD1981
- Where
- Sweden
- Volunteers
- 14 people, healthy volunteers welcome
- Sponsor
- AstraZeneca
HIV
Collection of Blood for Multiple Collaborative Studies
This study seeks to confidentially collect blood from HIV-positive individuals and HIV-negative controls to provide basic scientists with specimens for collaborative studies.
- Trial name
- NCT01336855
- Where
- United States
- Volunteers
- 2,000 people, healthy volunteers welcome
- Sponsor
- University of California, San Francisco
Healthy
A Study in Healthy Men to Test How BI 1595043 is Taken up in the Body When Given With or Without Food
The main objective of this trial is to investigate the relative bioavailability of BI 1595043 under fed state (Test, T) and under fasted state (Reference, R).
- Trial name
- NCT04789291
- Testing
- BI 1595043
- Where
- Belgium
- Volunteers
- 13 people, healthy volunteers welcome
- Sponsor
- Boehringer Ingelheim
Overweight, Healthy
Specificities of the Eccentric Exercise: Energy Expenditure and Nature of Oxidized Substrates
Main objective of this clinical trial is to compare the oxidation rates of main carbohydrate and lipid substrates during exercises carried out in eccentric dynamic pedaling mode on a cycloergometer compared to concentric…
- Conditions
- Overweight, Healthy, Men
- Trial name
- Speed-Enso (NCT05319704)
- Testing
- Test of effort on cycle on concentric or excentric mode, Kinetics on concentric or excentric mode during test of effort
- Where
- France
- Volunteers
- 12 people, healthy volunteers welcome
- Sponsor
- University Hospital, Clermont-Ferrand
Healthy Adults
Metabolic Availability of Lysine From Rice
The purpose of this study is to investigate the digestibility of the amino acid lysine in cooked rice in adult men using stable isotope technique.
- Trial name
- NCT01474226
- Testing
- Amino Acid Crystalline Lysine Amino Acid Mix, Cooked Rice containing Lysine
- Where
- Canada
- Volunteers
- 5 people, healthy volunteers welcome
- Sponsor
- The Hospital for Sick Children
Exercise Tolerance
Effect of Antioxidant on Endurance Performance in Healthy Men
oligomerized litchi fruit extract may enhance the submaximal endurance exercise performance
- Trial name
- NCT00731926
- Testing
- Oligomerized litchi fruit extract, VItamin C + Vitamin E mixture
- Volunteers
- 69 people, healthy volunteers welcome
- Sponsor
- Seoul National University Hospital
Vasomotor Symptoms as a Sex Hormone-dependent Disorder in Women and Men
A Study to Learn What Happens to Elinzanetant in the Body When Taken With or Without Carbamazepine, and How Safe it is in Healthy Men and Women Aged 18 to 60 Years.
Researchers are looking for a better way to treat people who have symptoms caused by hormonal changes, such as hot flashes. Before a treatment can be approved for patients to take, researchers do clinical studies to better…
- Trial name
- NCT05028608
- Testing
- Elinzanetant (BAY3427080), Midazolam, Carbamazepine
- Where
- Germany
- Volunteers
- 16 people, healthy volunteers welcome
- Sponsor
- Bayer
Erectile Dysfunction Following Radical Prostatectomy, Erectile Dysfunction
Safety, Tolerability and Pharmacokinetics (PK) Evaluation of BZ371A, Topically Administered
The purpose of this study is to evaluate pharmacokinetics, safety and tolerability profile of BZ371A topically administered in healthy patients.
- Conditions
- Erectile Dysfunction Following Radical Prostatectomy, Erectile Dysfunction, Prostate Cancer, Radical Prostatectomy
- Trial name
- NCT05332340
- Testing
- BZ371A
- Where
- Brazil
- Volunteers
- 12 people, healthy volunteers welcome
- Sponsor
- Biozeus Biopharmaceutical S.A.
Healthy Aging, Metabolic Syndrome
Impact of Healthy Diet on Metabolic Health in Men and Women
The overall aim of the present research program is to determine how a healthy whole-diet approach impacts on cardiometabolic health in adults.
- Conditions
- Healthy Aging, Metabolic Syndrome, Diet, Healthy
- Trial name
- NCT04062682
- Testing
- Healthy Diet
- Where
- Sweden
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- Örebro University, Sweden
Healthy
Effects of Growth Hormone Administration on Muscle Strength and Body Composition in Men Over 50 Years Old
The growth hormone (GH) secretion declines gradually with age, with studies demonstrating a progressive reduction of 14% secretion per decade of life beginning in the second decade.
- Trial name
- NCT01853566
- Testing
- growth hormone
- Where
- Brazil
- Volunteers
- 13 people
- Sponsor
- Universidade Federal do Rio de Janeiro
Prolonged QTc Interval, Pharmacokinetic
Effect of a Multiple-dose Oral Administration of CG5503 PR on the Electrical Activity of the Heart in 48 Healthy Men and Women
The effect of multiple oral administration of two doses of CG5503 PR (prolonged release) compared to placebo on the electrical activity of the heart were investigated.
- Trial name
- NCT03951402
- Testing
- 100 mg CG5503 (tapentadol hydrochloride) PR tablet, 400 mg Moxifloxacin tablet (overencapsulated)
- Where
- Germany
- Volunteers
- 48 people, healthy volunteers welcome
- Sponsor
- Grünenthal GmbH
Microvascular Function
Cephalic Phase Insulin Secretion and Capillary Recruitment in Healthy Men
Forty healthy volunteers will undergo two nailfold-videocapillaroscopy exams with a 10-minute interval between them, after an 10-h overnight fast in a temperature controlled room.
- Trial name
- NCT01145027
- Testing
- Breakfast tray
- Where
- Brazil
- Volunteers
- 39 people, healthy volunteers welcome
- Sponsor
- Rio de Janeiro State University
Muscle Hypertrophy, Muscle Strength
Upper Versus Lower Limb Responses to Higher Versus Lower Load Resistance Training in Young Men
Recent research suggests that performing resistance exercise training with relatively light loads is equally as effective at increasing muscle mass and muscle strength as performing resistance exercise training with relatively…
- Trial name
- NCT03993483
- Testing
- Unilateral resistance exercise
- Where
- Canada
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- McMaster University
Healthy Participants
A Research Study of a New Medicine (NNC0650-0013) in Healthy Men
This study is testing a new study medicine which may be used to treat people with type 2 diabetes. NNC0650-0013 is a new medicine, which cannot be prescribed by doctors.
- Trial name
- NCT06284798
- Testing
- NNC0650-0013 A
- Where
- Germany
- Volunteers
- 11 people
- Sponsor
- Novo Nordisk A/S
Healthy
Effect of Anagrelide Hydrochloride on Any Changes in Heart Function in Healthy Volunteers
According to the ICH Guidance Document E14, all non-antiarrhythmic drugs should be evaluated for their ability to prolong the QT interval which represents the duration of ventricular depolarization and subsequent repolarization.
- Trial name
- NCT01552928
- Testing
- Anagrelide 0.5 mg, Anagrelide 2.5 mg, Moxifloxacin
- Where
- France
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Shire
Healthy
A Study in Healthy Japanese Men to Test How Well Different Doses of BI 764198 Are Tolerated
The main objectives of this trial are to investigate safety and tolerability of BI 764198 in healthy male subjects following oral administration of single dose and multiple rising doses per day over 14 days.
- Trial name
- NCT04665700
- Testing
- BI 764198
- Where
- Japan
- Volunteers
- 44 people, healthy volunteers welcome
- Sponsor
- Boehringer Ingelheim
Healthy Subjects
Phase 1, Safety and Bronchopulmonary PK Study in Healthy Volunteers
This is a Phase 1, open-label, randomized, PK and safety study in a maximum of 25 healthy subjects who have provided a bronchoalveolar lavage (BAL) sample.
- Trial name
- BAL (NCT03691584)
- Testing
- TP-6076, Bronchoalveolar lavage
- Where
- United Kingdom
- Volunteers
- 8 people, healthy volunteers welcome
- Sponsor
- Tetraphase Pharmaceuticals, Inc
Prostate Cancer
Efficacy of a Couple-Focused mHealth Symptom Self-management Program
In this study, the investigators propose to test the efficacy of a couple-focused, web-based tailored prostate cancer symptom management program, Prostate Cancer Education and Resources for Couples (PERC) in a randomized clinical…
- Trial name
- NCT03489057
- Testing
- Prostate Cancer Education and Resources for Couples (PERC), usual care plus NCI website
- Where
- United States
- Volunteers
- 560 people, healthy volunteers welcome
- Sponsor
- UNC Lineberger Comprehensive Cancer Center