Clinical trials: Healthy Men
Healthy
A Study to Test How Well Healthy Men Tolerate Different Doses of BI 706321
The main objectives are: Part I: To investigate safety, tolerability, and pharmacokinetics (PK) of BI 706321 in healthy male subjects following oral administration of single rising doses.
- Trial name
- NCT03971695
- Testing
- BI 706321
- Where
- Germany
- Volunteers
- 73 people, healthy volunteers welcome
- Sponsor
- Boehringer Ingelheim
Healthy
A Study in Healthy Men to Test How BI 1358894 is Taken up in the Body and How Food Influences the Amount of BI 1358894 in the Blood
The main objective of Part 1 of this trial is to investigate the absolute bioavailability of BI 1358894 with an intravenous microdose formulation containing labelled [C-14] BI 1358894 and an unlabelled oral tablet formulation of…
- Trial name
- NCT04426851
- Testing
- BI 1358894, BI 1358894 (C-14) intravenous solution
- Where
- Netherlands
- Volunteers
- 12 people, healthy volunteers welcome
- Sponsor
- Boehringer Ingelheim
Physical Activity
Motivational Encouragement With Networks (MEN) for Healthy Eating Activity Resting Together (HEART) Health Study
The purpose of this research study is to determine if a health coaching intervention that includes exercise, good dietary habits, and good relaxation methods helps overweight men improve health and lose weight.
- Trial name
- MEN 4 HEART (NCT03693768)
- Testing
- Health coaching
- Where
- United States
- Volunteers
- 34 people, healthy volunteers welcome
- Sponsor
- University of Alabama at Birmingham
Pregnancy Related, Diet Modification
Motivational Interviewing for Getting Healthy TodaY Study
The present study aims to test and rigorously evaluate the effectiveness of a computer-assisted motivational interviewing (CAMI) intervention that has already been shown to be successful with young women by reducing the risk of…
- Trial name
- MIGHTY (NCT03410225)
- Testing
- CAMI-TPP, CAMI-Fitness
- Where
- 3 sites in United States
- Volunteers
- 26 people, healthy volunteers welcome
- Sponsor
- Columbia University
Exercise, Hypoxia
Regulation of Satellite Cells and Myogenesis in Response to Eccentric Resistance Exercise in Hypoxia
Satellite cells (SC) are muscle stem cells that once activated, proliferate, and differentiate into myocytes that finally fuse with an existing myofiber to regenerate or increase its mass. This process is called 'myogenesis'.
- Conditions
- Exercise, Hypoxia, Satellite Cells, Myogenesis
- Trial name
- NCT07341165
- Testing
- Resistance exercise on an isokinetic dynamometer, Vastus lateralis biopsy, Blood samples
- Where
- Belgium
- Volunteers
- 38 people, healthy volunteers welcome
- Sponsor
- Université Catholique de Louvain
Insulin Sensitivity
Insulin Resistance and Substrate Metabolism After Acute Erythropoietin (EPO) Administration
Recently EPO receptors have been found in human muscle tissue, but what is still not known is the physiological role of these receptors.
- Trial name
- NCT00793767
- Testing
- erythropoietin
- Where
- Denmark
- Volunteers
- 10 people, healthy volunteers welcome
- Sponsor
- Aarhus University Hospital
Cardiovascular Health
Pilot Study of Oligonol Supplementation to Promote Cardiovascular Health
The investigators hypothesize that acute consumption of Oligonol, a patented lychee fruit extract (Amino Up Chemical Co.) particularly rich in low molecular weight flavanols, will improve endothelial function, reduce platelet…
- Trial name
- NCT01162174
- Testing
- Oligonol
- Volunteers
- 16 people, healthy volunteers welcome
- Sponsor
- University of California, Davis
Obesity, Metabolically Healthy Obesity
Exercise and Diet Responses in Adult Men With Obesity by MC4R Genotype and Metabolic Health
This study evaluated whether differences in the MC4R rs17782313 gene variant and metabolic health status were associated with different responses to a 12-week exercise and dietary intervention in adult men with obesity.
- Conditions
- Obesity, Metabolically Healthy Obesity, Metabolically Unhealthy Obesity
- Trial name
- NCT07750197
- Testing
- Supervised Aerobic and Resistance Exercise
- Where
- China
- Volunteers
- 40 people
- Sponsor
- Harbin Sport University
Overweight, Obesity
Hockey Fans in Training (Hockey FIT): A Pilot Pragmatic Randomized Controlled Trial
The Hockey Fans in Training (Hockey FIT) program aims to improve overweight men's physical fitness, eating habits and health-related lifestyle choices through a lifestyle modification program in collaboration with two Ontario…
- Trial name
- NCT02396524
- Testing
- Hockey FIT Program
- Where
- 2 sites in Canada
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- Western University, Canada
Metabolic Syndrome, PreDiabetes
Lean Beef Consumption and Insulin Sensitivity in Men and Women With Risk Factors for Diabetes
The objective of this trial is to compare the effects of a healthy, lean beef diet and an average American, United States Department of Agriculture (USDA) style diet, that is low in saturated fatty acids (SFA), on insulin…
- Trial name
- NCT03202680
- Testing
- USDA Style Diet, Lean Beef Diet
- Where
- United States
- Volunteers
- 49 people
- Sponsor
- Midwest Center for Metabolic and Cardiovascular Research
Healthy
A Study in Healthy Men to Test Whether BI 1815368 Influences the Amount of Metformin in the Body
The main objective of this trial is to investigate the effect on the exposure of metformin in plasma when administered as an oral multiple dose together with multiple oral doses of BI 1815368 (Test, T) as compared to when…
- Trial name
- NCT06655220
- Testing
- Metformin hydrochloride, BI 1815368
- Where
- Germany
- Volunteers
- 14 people, healthy volunteers welcome
- Sponsor
- Boehringer Ingelheim
Healthy
Exploratory Study of Additional Use of Scopolamine Butylbromide, Glucagon or NPO-11 Following Single Dose of NPO-11 in Healthy Adult Men
The purpose of this study is to evaluate the safety and efficacy of the additional administration of scopolamine butylbromide, glucagon or NPO-11 following a single intragastric dose of NPO-11 during endoscopy in healthy adult…
- Trial name
- NCT00740324
- Testing
- NPO-11
- Where
- Japan
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Nihon Pharmaceutical Co., Ltd
Healthy Participants
Relative Bioavailability and Food Effect Study of IX-01 Capsules in Healthy Men
The purpose of this study is to compare the absorption and blood levels of IX-01 when given as a capsule compared to liquid form, and how food affects the absorption in healthy men.
- Trial name
- NCT02139826
- Testing
- IX-01
- Where
- United Kingdom
- Volunteers
- 12 people, healthy volunteers welcome
- Sponsor
- Ixchelsis Limited
Gaining Skeletal Muscle Mass and Strength
Exercise Training in Healthy Young Men
Resistance type exercise training has been shown to be a potent stimulus to increase skeletal muscle mass and strength in healthy men.
- Trial name
- NCT02222415
- Testing
- Exercise + Protein drink
- Where
- Netherlands
- Volunteers
- 44 people, healthy volunteers welcome
- Sponsor
- Maastricht University Medical Center
Anthrax
Efficacy and Safety of Anthrax Vaccine, GC1109
1. BACKGROUND The newly developed anthrax vaccine GC1109 has been proven safe and effective in preclinical studies. 2. OBJECTIVE To evaluate the immunogenicity and safety of the anthrax vaccine GC1109 in healthy male volunteers.
- Trial name
- NCT01867957
- Testing
- Low-dose GC1109, High-dose GC1109
- Where
- South Korea
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- Seoul National University Hospital
Sexual Dysfunction, Mediterranean Diet
Relationship Between Nutrition and Sexual Activity
Sexuality is integral to personality, influencing feelings, thoughts, actions, and physical and mental health. Female sexual dysfunction is a fairly common condition that covers four main areas: hypoactive sexual desire disorder…
- Conditions
- Sexual Dysfunction, Mediterranean Diet, Aphrodisiac Foods, Obesity
- Trial name
- NCT05632367
- Volunteers
- 185 people, healthy volunteers welcome
- Sponsor
- Istanbul University
Glycemic Control, Gastrointestinal Hormone Response
Mechanism of Action of Milk and Its Components on Glycemic Control in Healthy Young Men
The investigators hypothesize that the physiological effects of milk on satiety and glycemic control are mediated by the interaction between its macronutrient components by both insulin-dependent and independent mechanisms.
- Conditions
- Glycemic Control, Gastrointestinal Hormone Response, Healthy Young Men
- Trial name
- NCT01812967
- Testing
- Milk Fat, Milk Protein, Lactose
- Where
- Canada
- Volunteers
- 12 people, healthy volunteers welcome
- Sponsor
- University of Toronto
Healthy
ABG Oxidative Stress Study Protocol-1
This is a proof of concept study that evaluates the response to oxidative stress in healthy men after taking plant concentrates.
- Trial name
- NCT02213523
- Testing
- Plant concentrate A, Plant concentrate B, Plant concentrate C
- Where
- 2 sites in United States
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Access Business Group
Healthy Men, Raised Fasting Plasma Triacylglycerol Concentrations
Palmitic Acid in the Sn-2 Position of Triacylglycerols and Postprandial Lipemia
The purpose of this study is to determine whether high-fat meals rich in palmitic acid in the sn-2 position decrease lipaemia in men aged 40-70 y with higher than optimal fasting triacylglycerol concentrations.
- Trial name
- NCT01710280
- Testing
- High-fat meal containing native palm olein, High-fat meal containing interesterified palm olein
- Where
- United Kingdom
- Volunteers
- 11 people, healthy volunteers welcome
- Sponsor
- King's College London
Healthy
This Study in Healthy Men and Women Tests Whether BI 409306 Has an Effect on the ECG (Thorough QT Study)
The primary objective of this trial is to assess the effect of BI 409306 on the QT/QTc interval in healthy male and female volunteers as measured by the QTcF change from baseline compared with placebo.
- Trial name
- NCT03934203
- Testing
- BI 409306, Moxifloxacin
- Where
- Germany
- Volunteers
- 47 people, healthy volunteers welcome
- Sponsor
- Boehringer Ingelheim