Clinical trials: Healthy Older Adults
Healthy Aging
An Aging Healthy Intervention for Older Adults Delivered by Community Health Workers in Senior Centers: A Clinical Trial
The aCT Study will develop, implement and evaluate a community health worker (CHW) integrated model of care delivery for older adults that is senior center based.
- Trial name
- aCT (NCT07428174)
- Testing
- aCT CHW intervention
- Where
- United States
- Volunteers
- 250 people, healthy volunteers welcome
- Sponsor
- George Mason University
Tetanus, Tetanus Vaccine
Phase I/III Clinical Trial of Adsorbed Tetanus Vaccine
The study aimed to evaluate the safety and immunogenicity of an adsorbed tetanus vaccine in healthy individuals between 18 and 43 years of age.
- Trial name
- NCT07740733
- Testing
- Tetanus Toxoid (Adsorbed)
- Where
- China
- Volunteers
- 1,240 people, healthy volunteers welcome
- Sponsor
- Beijing Minhai Biotechnology Co., Ltd
Pneumococcal Disease
A Clinical Study to Evaluate the Safety, Tolerability, and Immunogenicity of VAX-31 With Influenza Vaccine in Adults ≥ 50 Years of Age
This is a Phase 3, randomized, double-blind study to evaluate the safety and immunogenicity of VAX-31 and seasonal influenza vaccine in pneumococcal-naïve adults ≥ 50 years when the two vaccines are administered at the same visit…
- Trial name
- NCT07365826
- Testing
- 31-valent pneumococcal conjugate vaccine, Seasonal Influenza Vaccine (SIV) (Flublok)
- Where
- 25 sites in United States
- Volunteers
- 1,390 people, healthy volunteers welcome
- Sponsor
- Vaxcyte, Inc.
Parkinson Disease
Pharmacokinetics of BIA 9-1067 and Its Metabolites in Healthy Male Elderly Subjects and in Healthy Male Young Subjects
The purpose of this study is to determine the effects of age on the pharmacokinetic (PK) profile of BIA 9-1067 and its metabolites.
- Trial name
- NCT02092168
- Testing
- BIA 9-1067
- Where
- France
- Volunteers
- 24 people, healthy volunteers welcome
- Sponsor
- Bial - Portela C S.A.
Cervical Cancer, Vulvar Cancer
Long-term Follow-up of Bivalent Human Papillomavirus (HPV) Vaccine Study in Women
This extension study aims to evaluate the long-term protection and immune response of the bivalent HPV vaccine in women aged 18-30 who participated in a previous efficacy study (311-HPV-1003).
- Conditions
- Cervical Cancer, Vulvar Cancer, Vaginal Cancer, CIN - Cervical Intraepithelial Neoplasia
- Trial name
- NCT06776055
- Testing
- HPV-16/18 vaccine
- Where
- 9 sites in China
- Volunteers
- 5,372 people, healthy volunteers welcome
- Sponsor
- Shanghai Zerun Biotechnology Co.,Ltd
Diet, Healthy Growth
'Food, Fun, Fresh, Family' Program for Healthy Eating and Growth for Elementary-age Children.
The goal of this community-based randomized trial in elementary-aged children and a caregiver (parent/guardian) is to test the effect of providing families with produce and grocery store gift cards (family support) in conjunction…
- Trial name
- FUEL (NCT06010784)
- Testing
- Family support, BGCAA's after-school program with CATCH curriculum
- Where
- United States
- Volunteers
- 119 people
- Sponsor
- University of Texas at Austin
Impaired Mobility
Nutrition Intervention for Older Adults and Research Training
Lack of effective interventions to improve diet quality among older urban adults represents a significant health problem. Simultaneously, enhancing the biomedical workforce is needed to meet growing US demands in research and…
- Trial name
- NIFOA-RT (NCT07898085)
- Testing
- Nutrition Intervention, Contact Control
- Where
- United States
- Volunteers
- 180 people, healthy volunteers welcome
- Sponsor
- University of Maryland, Baltimore
Heart Failure
A Study to Learn About the Taste of Vericiguat Given in Liquid Form in Healthy Male Participants Aged 18 to 45 Years
Heart failure is a condition in which the heart does not pump blood as well as it should. It can happen in both adults and children.
- Trial name
- NCT06474208
- Testing
- Formulation 1, Formulation 2, Formulation 3
- Where
- Germany
- Volunteers
- 19 people, healthy volunteers welcome
- Sponsor
- Bayer
Aging, Aging Well
Adjuvant Nitrate to Boost Exercise-induced Health Benefits in Older Adults
Aging-related functional declines are thought to be caused by hallmark biological processes that ultimately manifest in physical, mental, and metabolic impairments to compromise intrinsic capacity and healthspan.
- Conditions
- Aging, Aging Well, Healthy Aging
- Trial name
- BOOST-X (NCT07572266)
- Testing
- Nitrate enriched beetroot juice, Nitrate depleted beetroot juice, 12 week of combined exercise training
- Where
- United States
- Volunteers
- 226 people, healthy volunteers welcome
- Sponsor
- Florida Institute for Human and Machine Cognition
Healthy
Lay Theories of Health in Young and Middle Aged American Adults
This study is the second empirical investigation in a series of studies, examining what everyday people believe that it means to be healthy.
- Trial name
- NCT00458172
- Testing
- Assessment of beliefs and attitudes
- Where
- United States
- Volunteers
- 302 people, healthy volunteers welcome
- Sponsor
- University of Michigan
Cancer Survivors, Healthy Participant
A Study to Evaluate the Effects of the Combination of GI-102 With GIB-7 on Biomarkers of Aging in Healthy Adults and Cancer Survivors
This Phase 2a clinical study (GIANTS-1) aims to evaluate a novel dual-combination strategy using GI-102 and GIB-7 to address key pathological features of aging, including immunosenescence (the aging of the immune system)…
- Conditions
- Cancer Survivors, Healthy Participant, Elderly
- Trial name
- GIANTS-1 (NCT07363057)
- Testing
- GI-102 in combination with GIB-7
- Where
- 2 sites in Australia
- Volunteers
- 15 people, healthy volunteers welcome
- Sponsor
- GI Innovation, Inc.
H7N9 Influenza
Influenza A (H7N9) Vaccine Delivered Intradermally by High-density Microarray Patch (HD-MAP)
Study SP-1219-007 is a multi-centre, randomised, study designed to access the safety and tolerability of two doses of monovalent Influenza A (H7N9) vaccine delivered intradermally by a microarray patch delivery system in healthy…
- Trial name
- HD-MAP (NCT06417853)
- Testing
- Unadjuvanted Influenza A (H7N9) Monovalent Vaccine Injection, Unadjuvanted Influenza A (H7N9) Monovalent Vaccine Microarray Patch Delivery System (low dose HA), Adjuvanted Influenza A (H7N9) Monovalent Vaccine Microarray Patch Delivery System (high dose HA)
- Where
- 4 sites in Australia
- Volunteers
- 267 people, healthy volunteers welcome
- Sponsor
- Vaxxas Pty Ltd
Influenza
Safety and Immunogenicity of GPO Seasonal Trivalent Inactivated Influenza Vaccine in Healthy Thai Adults
The study is aim to evaluate the safety and immunogenicity of one dose (15 μg HA per strain per dose) of the GPO seasonal trivalent inactivated split virion influenza vaccine (Tri Fluvac) in healthy adults aged 18 to 49 years…
- Trial name
- NCT02894840
- Testing
- an inactivated influenza vaccine
- Volunteers
- 340 people, healthy volunteers welcome
- Sponsor
- Mahidol University
Hepatitis B
Consistency Study of Three Lots of Henogen's Adjuvanted Hepatitis B Vaccine When Given in 0, 1 Month Schedule
The study vaccine has been developed for use in pre-dialysis/ haemodialysis patients and immuno-compromised individuals who could have or had a sub-optimal response following vaccination for hepatitis B with currently available…
- Trial name
- NCT00480116
- Testing
- Adjuvanted Hepatitis B vaccine Lot 1, Adjuvanted Hepatitis B vaccine Lot 2, Adjuvanted Hep B vaccine Lot 3
- Where
- Czechia
- Volunteers
- 450 people, healthy volunteers welcome
- Sponsor
- Henogen
Healthy Aging
The Effects of Post Aerobic Exercise Hot Water Immersion on Physiological and Perceptual Responses in Physically Inactive Middle-aged Adults
This study will investigate the effects of post moderate intensity aerobic exercise hot water immersion on physiological and perceptual responses in physically inactive middle-aged adults when compared to moderate intensity…
- Trial name
- NCT05035004
- Testing
- Post exercise hot water immersion, Exercise, Hot water immersion
- Where
- United Kingdom
- Volunteers
- 16 people, healthy volunteers welcome
- Sponsor
- Coventry University
Influenza, Human
A Study to Assess the Immunogenicity and Safety of a Trivalent Influenza Vaccine Containing the 2013/2014 Formulation of Enzira® Vaccine in Healthy Volunteers
This is a study to assess the immune (antibody) response and safety of a bioCSL split virion, inactivated influenza vaccine containing the 2013/2014 formulation of Enzira® vaccine in healthy adult volunteers aged between 18 and…
- Trial name
- NCT01863433
- Testing
- Trivalent Influenza Vaccine
- Where
- United Kingdom
- Volunteers
- 120 people, healthy volunteers welcome
- Sponsor
- Seqirus
COVID-19, SARS-CoV-2 Pneumonia
A Clinical Trial of Immuno-bridging Between Different Manufacture Scales of Recombinant COVID-19 Vaccine (Sf9 Cell)
This is a randomized, double-blind , non-inferiority design study, to evaluate the Immunogenicity bridging between different manufacture scales of Recombinant COVID-19 Vaccine (Sf9 Cell) in healthy population aged 18-59 years…
- Trial name
- NCT05465785
- Testing
- Recombinant COVID-19 vaccine (Sf9 cell)
- Where
- China
- Volunteers
- 1,000 people, healthy volunteers welcome
- Sponsor
- WestVac Biopharma Co., Ltd.
Healthy
Respiratory Muscle Endurance Training in Healthy Elderly
Prevalence of hypertension in the elderly is high. Given that hypertension is the leading cause of cardiovascular disease worldwide, safe and efficacious treatment options for this condition are highly desired.
- Trial name
- RETE (NCT03730935)
- Testing
- Respiratory muscle endurance training
- Where
- Switzerland
- Volunteers
- 24 people, healthy volunteers welcome
- Sponsor
- Swiss Federal Institute of Technology
Pneumococcal Pneumonia, Pneumonia, Bacterial
Phase I to Test a New Pneumococcal Vaccine
To obtain first-in-human data on a new candidate vaccine against Streptococcus pneumoniae in healthy adult and elderly volunteers.
- Trial name
- NCT03303976
- Testing
- Bioconjugate pneumococcal vaccine, Multivalent plain polysaccharide vaccine
- Where
- Germany
- Volunteers
- 72 people, healthy volunteers welcome
- Sponsor
- LimmaTech Biologics AG
Zika Virus, Zika Virus Infection
Randomized, Placebo-controlled, Observer-blinded Phase 1 Safety and Immunogenicity Study of Inactivated Zika Virus Vaccine Candidate in Healthy Adults
In this Phase 1 study, two target dose levels of VLA1601, a purified, inactivated, whole Zika virus (ZIKV) vaccine candidate adsorbed on aluminum hydroxide (alum) will be evaluated: 6 antigen units (AU) and 3 AU of inactivated…
- Trial name
- NCT03425149
- Testing
- VLA1601
- Where
- United States
- Volunteers
- 67 people, healthy volunteers welcome
- Sponsor
- Valneva Austria GmbH
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