Clinical trials: Healthy Older Adults
Seasonal Influenza, Influenza
Humoral and Cell Mediated Immunity and Safety of MF59C.1-adjuvanted Subunit Influenza Vaccine or a Conventional Subunit Influenza Vaccine in Previously Unvaccinated Healthy Subjects
This study aims to evaluate the immunogenicity, by means of cell mediated immunity (CMI) and hemagglutination inhibition (HI) assay, and also the safety of a MF59C.1-adjuvanted subunit influenza vaccine compared with a…
- Conditions
- Seasonal Influenza, Influenza, Influenza Due to Unspecified Influenza Virus, Human Influenza
- Trial name
- NCT01342796
- Testing
- MF59C.1-adjuvanted subunit influenza vaccine, Sub unit, Inactivated, Influenza vaccine
- Where
- 2 sites in Belgium
- Volunteers
- 84 people, healthy volunteers welcome
- Sponsor
- Novartis Vaccines
Cardiovascular Diseases, Cardiovascular Risk Factor
The Effects of a Mobile Health Intervention and Health Coach Text Messaging on Cardiovascular Risk of Older Adults
This study, "Fitness Intensive Therapy (Get FIT) to Promote Healthy Living in Older Adults", will test a mobile-health based intervention which includes use of a Fitbit activity tracker for 3 months, a smartphone application that…
- Trial name
- GET FIT (NCT03720327)
- Testing
- Get FIT, Get FIT+
- Where
- 5 sites in United States
- Volunteers
- 54 people
- Sponsor
- University of California, Irvine
H5N1 Influenza
H5N1 Vaccine Study in Japanese Adults
The purpose of this study is to obtain immunogenicity and safety data of two different dose levels of an H5N1 pandemic influenza vaccine in a healthy Japanese adult population aged 18 to 59 years.
- Trial name
- NCT01382329
- Testing
- H5N1 (pre-)pandemic influenza vaccine (whole virion, Vero Cell derived, inactivated)
- Where
- 3 sites in Japan
- Volunteers
- 340 people, healthy volunteers welcome
- Sponsor
- Alachua Government Services, Inc.
Influenza
Inactivated Split Virus Seasonal Influenza Vaccine (Vero Cell-Derived)
The purpose of this study is to determine if a Vero cell-derived trivalent seasonal influenza vaccine produced by the modified manufacturing process: 1.
- Trial name
- NCT01773928
- Testing
- Vero cell-derived trivalent influenza vaccine manufactured with the modified manufacturing process (VCIV modified), VCIV manufactured with the current manufacturing process (VCIV current), Fluzone®, licensed trivalent influenza vaccine (TIV)
- Where
- 20 sites in United States
- Volunteers
- 1,928 people, healthy volunteers welcome
- Sponsor
- Alachua Government Services, Inc.
Aging
Evaluation of the Efficacy of Calcium a -Ketoglutarate(AKG-Ca) in Improving Human Aging
This randomized, double-blind, placebo-controlled clinical trial aims to evaluate the effects of calcium alpha-ketoglutarate (CaAKG) supplementation on biological aging and age-related health indicators in middle-aged and older…
- Trial name
- NCT07114536
- Testing
- Calcium-a-ketoglutarate
- Where
- China
- Volunteers
- 34 people, healthy volunteers welcome
- Sponsor
- Shenzhen Hygieia Biotech Co., Ltd
Healthy Adult Participants, Controlled Hypertension
Ginkgo Active App-Based Exercise Training
The purpose of this study is to investigate the effectiveness and usability of a Gingko app based exercise training in middle and older aged adults.
- Conditions
- Healthy Adult Participants, Controlled Hypertension, Controlled Diabetes
- Trial name
- NCT07411339
- Testing
- Ginkgo App-based Exercise Training, NIA Booklet Exercise
- Volunteers
- healthy volunteers welcome
- Sponsor
- University of Maryland, Baltimore
Healthy Adult Subjects and Healthy Elderly Subjects
A Phase 1 Study To Characterize The Safety, Tolerability, PK And PK Of Repeat Doses Of PF-06648671 In Healthy Adults And Healthy Elderly Subjects
This is an investigator-and-subject blind, phase 1 study to characterize the safety, tolerability, pharmacokinetics and central and peripheral pharmacodynamics of 14-day repeated ascending doses of PF-06648671 once a day in…
- Trial name
- NCT02440100
- Testing
- PF-06648671, Midazolam
- Where
- Belgium
- Volunteers
- 92 people, healthy volunteers welcome
- Sponsor
- Pfizer
Frailty, Frailty Syndrome
Smart Home Technologies for Assessing and Monitoring Frailty in Older Adults
This project aims to address the impact of frailty on older adults, particularly its connection to cognitive impairments such as dementia.
- Conditions
- Frailty, Frailty Syndrome, Frail Elderly Syndrome, Pre-Frailty
- Trial name
- NCT05961319
- Testing
- Smart-Home Monitoring
- Where
- 2 sites in Canada
- Volunteers
- 21 people, healthy volunteers welcome
- Sponsor
- University of Alberta
Anhedonia in Healthy Volunteers, Older Adults (50-90 Years)
A Study of Psychedelics in Healthy Older Adults With Low Well-being
This study is being conducted to understand changes in brain activity following administration of two different drugs (Psilocybin and Dextromethorphan) in older adults with low well-being.
- Trial name
- OAD1 (NCT07386730)
- Testing
- Psilocybin (drug), Dextromethorphan (DXM)
- Where
- United States
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- Jennifer Mitchell
Mild Cognitive Impairment (MCI), Mild Cognitive Impairment (MCI) Due to Alzheimer's Disease
Mindfulness for Cognition in Early-stage Alzheimer's Disease
The goal of this clinical trial is to learn if mindfulness meditation can improve outcomes in older adults with and without cognitive impairment. The main questions it aims to answer are: 1.
- Conditions
- Mild Cognitive Impairment (MCI), Mild Cognitive Impairment (MCI) Due to Alzheimer's Disease, TBI (Traumatic Brain Injury), Aging
- Trial name
- NCT06792877
- Testing
- Mindfulness Intervention, Waitlist then mindfulness
- Where
- United States
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- VA Boston Healthcare System
Gut -Microbiota, Older People
Probiotics and Active Aging: Enhancing Gut Health
The general objective of this clinical trial is to assess the physical fitness and gut microbiota of older adults, thereby highlighting the importance of focusing on health maintenance.
- Conditions
- Gut -Microbiota, Older People, Physical Activity, Physical Fitness
- Trial name
- PAAEGH (NCT07033637)
- Testing
- Dietary Supplement, Structured Physical Activity Program
- Volunteers
- 90 people, healthy volunteers welcome
- Sponsor
- Jose Luis Felipe
Gait, Unsteady, Healthy
Effect of Gait Training With a Walking Assist Robot on Gait Function and Balance in Elderly Adults
The purpose of this study was to investigate the effects of gait training with the new wearable hip assist robot developed by Samsung Advance Institute of Technology (Samsung Electronics Co, Ltd, Korea) in elderly adults.
- Trial name
- NCT03325998
- Testing
- Samsung Hip Assist v1
- Where
- South Korea
- Volunteers
- 8 people
- Sponsor
- Samsung Medical Center
Healthy Older Adults
Interactive Effects of Sodium and Potassium on Vascular Health in Older Adults
The goal of this clinical trial is to determine if a high potassium intake can counteract the harmful effects of excess sodium on endothelial function in older adults with no history of cardiometabolic disease.
- Trial name
- NCT07649005
- Testing
- low sodium/low potassium diet, high sodium/low potassium diet, high sodium/high potassium diet
- Where
- United States
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Florida State University
Healthy Ageing
Design and Testing of a Person-centered Telecare Model for Healthy Aging in Bogotá
What is the purpose of this study? The main goal of this study is to design and test a new "telecare" model to help adults aged 80 and older in Bogotá live healthier and more independent lives.
- Trial name
- NCT07447492
- Testing
- Telecare and Case Management Program, Usual Care
- Where
- Colombia
- Volunteers
- 155 people, healthy volunteers welcome
- Sponsor
- Hospital Universitario San Ignacio
Mild Cognitive Impairment, Healthy
Imaging Tau Deposition in the Brain of Elderly Subjects
Cerebral accumulation of tau and beta-amyloid are major factors of Alzheimer's disease pathology. A novel Positron Emission Tomography (PET) tracer (18-F-AV-1451) now offers the ability to study tau protein deposition in vivo in…
- Conditions
- Mild Cognitive Impairment, Healthy, Alzheimer Disease, Neurocognitive Disorders
- Trial name
- Add-Tau (NCT02958670)
- Testing
- 18F-AV-1451 (Tau-PET tracer)
- Where
- Switzerland
- Volunteers
- 141 people, healthy volunteers welcome
- Sponsor
- University of Zurich
Physical Fitness, Aging
China Healthy Aging and Fitness Longitudinal Study
The China Healthy Aging and Fitness Longitudinal Study (CHALF) is a nationwide prospective observational study designed to investigate how physical activity, exercise, and physical fitness are associated with health and aging…
- Trial name
- CHALF (NCT07881094)
- Where
- China
- Volunteers
- 8,960 people, healthy volunteers welcome
- Sponsor
- China Institute of Sport Science
Poliomyelitis
Phase III Clinical Trial of Sabin Strain Inactivated Poliovirus Vaccine (Vero Cell)
The study aimed to evaluate the safety and immunogenicity of a Sabin strain-based inactivated polio vaccine in infants aged two months (60~89 days).
- Trial name
- NCT07297186
- Testing
- sIPV, wIPV
- Where
- China
- Volunteers
- 1,200 people, healthy volunteers welcome
- Sponsor
- Beijing Minhai Biotechnology Co., Ltd
Healthy
A 28 Day Parallel Group Study to Assess the Effects of RDN-929
Eligibility will be assessed during a screening period of up to 4 weeks. Subjects will take study medication once daily up to and including Day 28. Safety, tolerability and PK will be measured at each visit.
- Trial name
- NCT03963973
- Testing
- RDN-929 oral capsule
- Where
- 2 sites in Netherlands
- Volunteers
- 7 people, healthy volunteers welcome
- Sponsor
- Alkermes, Inc.
Healthy
Trial to Assess Safety, Tolerability, and Immunogenicity of Influenza Virus Vaccine, Trivalent, Types A and B, Live Cold-adapted (CAIV-T) in Healthy Children
The study was designed to determine the number of doses of CAIV-T required to effectively immunize children and adolescents in the 6 to 17 year age group.
- Trial name
- FluMist (NCT00192270)
- Testing
- CAIV-T
- Where
- 3 sites in Belgium, Finland
- Volunteers
- 498 people, healthy volunteers welcome
- Sponsor
- MedImmune LLC
Healthy Aging, Muscle Function
The Effect of Urolithin A (Mitopure®) Supplementation on Muscle Strength in Healthy Middle-Aged Adults
This is a randomised, double-blind, placebo-controlled, parallel study to assess the effects of Urolithin A (Mitopure®) supplementation on muscle strength and performance in healthy middle-aged adults.
- Trial name
- ATLAS 2 (NCT07231783)
- Testing
- Mitopure® 500mg, Mitopure® 1000mg
- Where
- Ireland
- Volunteers
- 120 people, healthy volunteers welcome
- Sponsor
- Amazentis SA
The first 1,020 results can be paged through. Add a filter or change the sort order to reach the rest.