Clinical trials: Healthy Older Adults
Healthy Aging, Cognitive Function 1, Social
Robot-Assisted Tabletop Games for Community-Dwelling Older Adults
This study evaluated a 12-week robot-assisted tabletop game program for community-dwelling older adults in Taiwan. Participants attended one 100-minute group session per week for 12 weeks.
- Conditions
- Healthy Aging, Cognitive Function 1, Social, Physical Function in Older Adults
- Trial name
- NCT07907003
- Testing
- Robot-Assisted Tabletop Game Program
- Where
- Taiwan
- Volunteers
- 93 people, healthy volunteers welcome
- Sponsor
- Chang Gung University of Science and Technology
Healthy Volunteers
Immunogenicity and Safety of Tetravalent Dengue Vaccine (TDV) Co-administered With an Hepatitis A Virus Vaccine
The purpose of this study is to investigate the immunogenicity and safety of the concomitant administration of TDV (subcutaneous [SC] injection) and of hepatitis A virus (HAV) vaccine (intramuscular [IM] injection) in healthy…
- Trial name
- NCT03525119
- Testing
- TDV, HAV Vaccine
- Where
- 10 sites in United Kingdom
- Volunteers
- 900 people, healthy volunteers welcome
- Sponsor
- Takeda
Healthy
The Effect of Relaxation Response Training on Declarative Memory and Salivary Cortisol in Older Adults
To evaluate whether a 5-week relaxation response intervention influences the learning, memory or attention of healthy older adults.
- Trial name
- NCT00179530
- Testing
- Relaxation Response
- Volunteers
- 16 people, healthy volunteers welcome
- Sponsor
- Beth Israel Deaconess Medical Center
Charcot-Marie-Tooth Disease
Observational Study of Neuromuscular Function in CMT Type 1&2 and Healthy Controls
The primary aim of this study is to discover whether patients with CMT type 1 and 2 have neuromuscular junction transmission deficits.
- Trial name
- ESTABLISH (NCT04980807)
- Where
- 2 sites in United States, Denmark
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- NMD Pharma A/S
Sarcopenia, Healthy Elderly
Exercise and Nutritional Supplementation
To understand the effects of a novel dietary supplement when used in conjunction with a healthy lifestyle exercise program and to define biomarkers that are specific to sarcopenia.
- Conditions
- Sarcopenia, Healthy Elderly, Healthy Young
- Trial name
- ENSASL (NCT03536871)
- Testing
- multi-nutrient supplement, Exercise
- Where
- Canada
- Volunteers
- 45 people, healthy volunteers welcome
- Sponsor
- McMaster University
Healthy
Evaluation of Aging, Autonomic Nervous System Activity and Cardiovascular Events
The regulatory effects of the autonomic nervous system (ANS) concern almost all organs which permanently feed information back to this global biological vigilance system controlling allostasis.
- Trial name
- PROOF (NCT00759304)
- Where
- France
- Volunteers
- 1,011 people, healthy volunteers welcome
- Sponsor
- Centre Hospitalier Universitaire de Saint Etienne
Visual Processing Speed
Iowa Healthy and Active Minds Study
This is second-generation study based on results from ACTIVE (Advanced Cognitive Training for Independent and Vital Elderly). This four-arm study is known as IHAMS (the Iowa Healthy and Active Minds Study).
- Trial name
- IHAMS (NCT01165463)
- Testing
- SOPT basic training, Crossword Puzzles, SOPT booster training
- Where
- United States
- Volunteers
- 681 people, healthy volunteers welcome
- Sponsor
- Fredric D Wolinsky
Aging, Healthy Aging
10-week Yoga Practice Effect on Cognitive and Motor Function in Older Adults
Thirty-three healthy elderly people, who were classified into two age groups, participated in this study. All participants had not practiced yoga before and were asked not to perform any sports activities while the research was…
- Trial name
- BDNF (NCT04314921)
- Testing
- Yoga trainings
- Where
- Lithuania
- Volunteers
- 33 people, healthy volunteers welcome
- Sponsor
- Lithuanian Sports University
Cognitive Performance
Evaluation of the Effects of Berry Leaf Extract on Cognitive Processing in Healthy Elderly Adults
This study aims to explore the positive effect of a dietary supplement composed of berry leaf extract on the cognitive performance and regulation of stress, mood, sleep and fatigue in healthy elderly adults with self-reported…
- Trial name
- SLE (NCT06819163)
- Testing
- Berry leaf extract
- Where
- Belgium
- Volunteers
- 109 people, healthy volunteers welcome
- Sponsor
- Seppic
Frail Elderly
Pilot Study of Virtual Gait Training in Older Adults
Older individuals suffer from falls and fear of falling. The purpose of this study was to determine the effectiveness of a novel virtual gait training on walking performance and fear of falling in older adults, and to evaluate…
- Trial name
- NCT01607736
- Testing
- Virtual Gait Training
- Where
- Switzerland
- Volunteers
- 12 people, healthy volunteers welcome
- Sponsor
- University Hospital, Basel, Switzerland
Schizophrenia, Cognition Disorders
The Effect of Nicotine on Arousal, Cognition and Social Cognition in Young and Elderly Healthy Subjects.
This study in young and elderly healthy subjects will investigate the effect of nicotine on arousal, cognitive task and social cognition after acute dose administration.
- Trial name
- NCT01181934
- Testing
- A643 (nicotine)
- Volunteers
- 32 people, healthy volunteers welcome
- Sponsor
- Janssen Pharmaceutica N.V., Belgium
Tuberculosis
Phase I Clinical Trial to Evaluate the Safety of Recombinant Mycobacterium Tuberculosis Fusion Protein (EEC) in Healthy Adults Aged 18-65 and Patients With Pulmonary Tuberculosis
The study is to enroll 60 participants aged 18-65 years old, including 30 healthy subjects and 30 tuberculosis patients. Low-dose (2.5 μg/ml), medium-dose (5 μg/ml), and high-dose (10 μg/ml) studies will be conducted separately…
- Trial name
- NCT06224608
- Testing
- Recombinant Mycobacterium Tuberculosis Fusion Protein (EEC)
- Where
- 2 sites in China
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Chengdu CoenBiotech Co., Ltd
Positive Mental Health
Family FINGER: Lifestyle Intervention Among Older Caregivers
The Family FINGER study enrolls caregivers aged 65 or older who live with and care for a spouse with cognitive impairment in North Savo, Finland (estimated n=100).
- Trial name
- NCT07627386
- Testing
- a multidomain lifestyle intervention
- Where
- Finland
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Tarja Välimäki
Healthy
Study Evaluating The Safety And Tolerability Of Administration Of Single Oral Doses Of SAM-760 To Healthy Subjects
This study will assess the safety and tolerability of ascending single oral doses of SAM-760 in healthy young adult and healthy elderly subjects.
- Trial name
- NCT00948662
- Testing
- SAM-760, ketoconazole
- Where
- France
- Volunteers
- 124 people, healthy volunteers welcome
- Sponsor
- Pfizer
Infections, Meningococcal
Study to Evaluate Meningococcal Serogroups A,C,W-135,Y Conjugate Vaccine When Given as 1 Dose to Healthy Subjects Aged 18-25 Years
The purpose of this study is to evaluate the safety, reactogenicity, immunogenicity and persistence up to three years after administration of one dose of the MenACWY conjugate vaccine when given to young adults aged 18-25 years.
- Trial name
- NCT00196950
- Testing
- Meningococcal (vaccine)
- Where
- Belgium
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- GlaxoSmithKline
Aging, Healthy
Safe-Age Study: A Safety and Tolerability Study of a Nutritional Supplement in Healthy Older Adults
The goal of this clinical trial is to evaluate the safety and tolerability of the nutritional supplement Youniqor in healthy older adults.
- Trial name
- SAFE-AGE (NCT07442097)
- Testing
- Youniqor
- Where
- India
- Volunteers
- 16 people, healthy volunteers welcome
- Sponsor
- YOXLO B.V.
Influenza
Study to Evaluate the Safety, Tolerance and Immunogenicity of Fluviral™ in Healthy Adults
The purpose of the study is to evaluate the safety, tolerance and immunogenicity of Fluviral™ in healthy adults aged 18-64 years.
- Trial name
- NCT01389479
- Testing
- Fluviral™, Fluzone®
- Volunteers
- 1,000 people, healthy volunteers welcome
- Sponsor
- GlaxoSmithKline
Pneumonia, Bacterial
Trial to Evaluate Safety and Immune Response of an Investigational Pneumococcal Vaccine in Adults Aged 50 To 64 Years
This study will evaluate the safety and immune response of a new formulation of pneumococcal vaccine, PnMAPS30plus, in healthy adults aged 50 to 64 years.
- Trial name
- NCT07428759
- Testing
- Pn-MAPS30plus, PCV20
- Where
- 2 sites in Australia
- Volunteers
- 122 people, healthy volunteers welcome
- Sponsor
- GlaxoSmithKline
Pertussis Vaccine
Study Evaluating the Safety of a Recombinant Acellular Pertussis Vaccine in Adults
This pivotal safety trial aims to extend the safety database for BioNet recombinant acellular pertussis (aP) vaccine (Pertagen®) in a larger population of adults and evaluate the incidence and characteristics of adverse drug…
- Trial name
- PertaSafe (NCT06798831)
- Testing
- Pertussis containing vaccine
- Where
- 3 sites in Thailand
- Volunteers
- 2,399 people, healthy volunteers welcome
- Sponsor
- BioNet-Asia Co., Ltd.
Lower Extremity Weakness Distal, Distorted; Balance
Assessment and Referral Versus Exercise in Primary Prevention of Falls: PA Healthy Steps Program
Older adults at high risk of falls will complete the PA Healthy Steps program. This program will be implemented by research staff who will follow the training manual and implement the program as it was designed to assess the…
- Trial name
- NCT01552551
- Testing
- Assessment and education, Healthy Steps with Falls Case Management, Healthy Steps in Motion
- Where
- United States
- Volunteers
- 189 people
- Sponsor
- University of Pittsburgh
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