Clinical trials: Healthy Patients
Healthy Elderly
MAD Study of NX210c
This study will investigate the safety and tolerability of multiple intravenous infusions of NX210c with two ascending doses as well as NX210c pharmacokinetics (PK), and pharmacodynamics (PD) effects in healthy elderly subjects.
- Trial name
- CHDR2235 (NCT05827653)
- Testing
- NX210c
- Where
- Netherlands
- Volunteers
- 29 people, healthy volunteers welcome
- Sponsor
- Axoltis Pharma
Healthy Subjects, Patient Performing an MRI Examination
Optimization of the Acquisition Sequence to Improve the Quality and Comfort of Magnetic Resonance Imaging Exam
The purpose of this study is to evaluate the optimization of MRI acquisition sequences.
- Trial name
- AIMANT (NCT04645628)
- Testing
- MRI examination
- Where
- France
- Volunteers
- 720 people, healthy volunteers welcome
- Sponsor
- Central Hospital, Nancy, France
Nervous System Disease, Healthy Volunteer
Diagnosis and History Study of Patients With Different Neurological Conditions
This protocol is a screening and natural history protocol, which allows for evaluation of patients and families where neurological conditions are present for enrollment into other studies and will also be used to screen healthy…
- Trial name
- NCT00001367
- Where
- United States
- Volunteers
- 3,813 people
- Sponsor
- National Institute of Neurological Disorders and Stroke (NINDS)
Rheumatoid Arthritis
Physical Activity Behavior of Rheumatoid Arthritis Patients and Healthy Controls
The purpose of the study is to compare physical activity behaviour of rheumatoid arthritis patients with healthy matched controls.
- Trial name
- NCT01228812
- Where
- Switzerland
- Volunteers
- 505 people
- Sponsor
- University of Lausanne
Smoking, Airway Obstruction
Effect of the Salbutamol on Mechanical Properties of Respiratory System
The aim of this study is to assess the bronchodilator response of salbutamol on respiratory mechanics of healthy individuals, smokers and COPD with varying degrees of airway obstruction.
- Trial name
- NCT01521572
- Testing
- Salbutamol sulphate
- Where
- Brazil
- Volunteers
- 200 people, healthy volunteers welcome
- Sponsor
- Rio de Janeiro State University
Intensive Care Unit, Muscle Strength
Normative Values for Peripheral Muscle Strength in Critical Patients and Healthy Individuals
Muscle strength is an important indicator of overall health and is a factor that has been associated with increased mortality in critical patients.
- Trial name
- HHD-ICU (NCT06296381)
- Where
- 4 sites in Brazil
- Volunteers
- 180 people
- Sponsor
- University of Pernambuco
Prevention of Childhood Obesity, Community Health Education
EFFECT OF A ONLINE NUTRITION EDUCATION PROGRAM IN PRESCHOOLER'S FAMILIES ON THEIR ADHERENCE TO THE MEDITERRANEAN DIET
Questions: What's the effect of an online nutritional educational program in preschoolers families on the adherence to the mediterranean diet? What's the effect of this program on the BMI at 3 years follow-up? Study Description A…
- Trial name
- ELIKUME (NCT06828367)
- Testing
- Online family educational intervention and cooking workshop
- Where
- Spain
- Volunteers
- 160 people, healthy volunteers welcome
- Sponsor
- Fundacion Miguel Servet
Healthy, Schizophrenia
Electrophysiology and Blood Flow in Patients With Schizophrenia and Their Siblings
This study will explore how the brain works during memory testing in an effort to understand why some patients with schizophrenia have memory difficulties.
- Trial name
- NCT00001921
- Where
- United States
- Volunteers
- 1,386 people, healthy volunteers welcome
- Sponsor
- National Institute of Mental Health (NIMH)
Stroke
Influence of Theta Burst Stimulation and Carbidopa-Levodopa on Motor Performance in Stroke Patients
This study will examine whether transcranial magnetic stimulation (TMS) of the brain used in combination with carbidopa-levodopa is more effective in temporarily improving the speed of hand movement in stoke patients than TMS…
- Trial name
- NCT00366184
- Where
- United States
- Volunteers
- 20 people
- Sponsor
- National Institute of Neurological Disorders and Stroke (NINDS)
Cerebrovascular Disorders, Platelet Refractoriness
Platelet Antisedimentation Rate and Multiplate Exams in Patients on Antiplatelet Therapy and Controls
To search for simple laboratory methods selecting patients with low/non-responsiveness to P2Y12 receptor antagonists.
- Conditions
- Cerebrovascular Disorders, Platelet Refractoriness, Platelet Aggregation, Spontaneous
- Trial name
- NCT03679858
- Testing
- Platelet function test
- Where
- Hungary
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- University of Pecs
Breast Cancer
Nipple Secretion Samples in Detecting Breast Cancer in Patients and Healthy Participants Undergoing Breast Cancer Screening, Breast Diagnostic Studies, or Treatment for Benign Breast Disease
RATIONALE: Diagnostic procedures that measure biomarker levels in nipple section and blood samples, may help in the early detection of breast cancer.
- Trial name
- NCT00813878
- Testing
- protein analysis, protein expression analysis, proteomic profiling
- Where
- United States
- Volunteers
- 126 people
- Sponsor
- City of Hope Medical Center
Idiopathic Pulmonary Arterial Hypertension
The Study of Apelin-APJ System on Pulmonary Hypertension Patients and Healthy Subjects
The purpose of this study is to Determine blood peptide levels and investigate any tissue gradients of apelin in patients with idiopathic pulmonary arterial hypertension and healthy volunteers.
- Trial name
- EXAP (NCT01590108)
- Testing
- (Pyr1)apelin-13, Saline
- Where
- 2 sites in United Kingdom
- Volunteers
- 12 people, healthy volunteers welcome
- Sponsor
- Imperial College London
Healthy Volunteer, Rheumatoid Arthritis
Phenomics in Autoimmune and Inflammatory Diseases
The family of inflammatory/autoimmune systemic diseases (IAD) form a continuum from pure inflammatory diseases to pure autoimmune diseases, encompassing a large panel of inflammatory diseases with some autoimmune components, and…
- Conditions
- Healthy Volunteer, Rheumatoid Arthritis, Ankylosing Spondylitis, Systemic Lupus Erythematosus/Antiphospholipid Syndrome
- Trial name
- TRANSIMMUNOM (NCT02466217)
- Testing
- 1: AID groups, 2: Control groups
- Where
- 2 sites in France
- Volunteers
- 537 people, healthy volunteers welcome
- Sponsor
- Assistance Publique - Hôpitaux de Paris
ICU Patients, Healthy Lung
Effects of End-expiratory Positive Pressure Optimization in Intubated Patients With Healthy Lung or Acute Respiratory Distress Syndrome
PEEP titration is a recommended during invasive mechanical ventilation of ICU patients. However, little is known about the right way to conduct this titration.
- Conditions
- ICU Patients, Healthy Lung, Positive End-Expiratory Pressure, ARDS
- Trial name
- PEEP-Réa (NCT04503876)
- Testing
- Increasing PEEP setting, Decreasing PEEP setting
- Where
- France
- Volunteers
- 45 people
- Sponsor
- University Hospital, Clermont-Ferrand
Osteoarthritis
Safety, Tolerability, Pharmacokinetics and Pharmacodynamics of Multiple Rising Oral Doses of BI 1026706 in Male and Female Healthy Subjects and Patients With Osteoarthritis of the Knee
To investigate the safety and tolerability of BI 1026706 in male and female healthy subjects and osteoarthritis (OA) patients following oral administration of repeated rising doses To explore the pharmacokinetics after multiple…
- Trial name
- NCT02126826
- Testing
- BI 1026706
- Where
- Germany
- Volunteers
- 58 people, healthy volunteers welcome
- Sponsor
- Boehringer Ingelheim
Healthy Participants and Patients With Narcolepsy
Phase 1 TAK-925 Study in Healthy Adult and Elderly Volunteers and Participants With Narcolepsy
The purpose of this study is to investigate safety, tolerability, and pharmacokinetics of TAK-925 when a single dose of TAK-925 is administered to healthy adult participants, healthy elderly participants and patients with type 1…
- Trial name
- NCT03332784
- Testing
- TAK-925
- Where
- 3 sites in Japan
- Volunteers
- 58 people, healthy volunteers welcome
- Sponsor
- Takeda
IOP Changes Due to Anesthesia (Healthy Patients)
The Effect of Different Sevoflurane Concentrations on Intraocular Pressure in Patients Undergoing Ocular Surgery Under General Anesthesia
One important goal in anesthetic management during ocular surgery is to provide adequate control of intraocular pressure (IOP). An increase in IOP may be catastrophic in patients with glaucoma or a penetrating open-eye injury.
- Trial name
- NCT01575626
- Testing
- Sevoflurane
- Where
- Israel
- Volunteers
- 30 people
- Sponsor
- Tel-Aviv Sourasky Medical Center
Stroke, Hemiplegia
Robot-Assisted Stroke Rehabilitation Based on Patient-Therapist Interactions
Our study goal is to assess natural patient-therapist interactions in order to map such human-human activities to robot-human interactions.
- Conditions
- Stroke, Hemiplegia, Healthy
- Trial name
- Baxter (NCT02806843)
- Testing
- Rehab InterCap system and 3D Kinect
- Where
- United States
- Volunteers
- 65 people, healthy volunteers welcome
- Sponsor
- University of Pennsylvania
Healthy Volunteer, Patients Under Vitamin K Antagonist (VKA)
Validation of a Portable Medical Device for Diagnostic in Vitro
This clinical trial is about a new technology, named HEMOPTIC. It enables to mesure time of blood coagulation for monitoring of patients under Vitamin K antagonist (VKA).
- Trial name
- HEMOPTIC (NCT02843958)
- Testing
- HEMOPTIC
- Where
- France
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- University Hospital, Grenoble
Healthy, Hyperalgesia
Positron Emission Tomography to Measure Pain and Pain Control
This study will examine how the brain processes pain signals and how the different parts of the brain work with each other in response to painful stimuli.
- Conditions
- Healthy, Hyperalgesia, Pain, Peripheral Nervous System Disease
- Trial name
- NCT00001307
- Testing
- Oxygen-15 Water, Capsaicin
- Where
- United States
- Volunteers
- 273 people, healthy volunteers welcome
- Sponsor
- National Institute of Dental and Craniofacial Research (NIDCR)
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