Clinical trials: Healthy People
Lyme Disease
First Clinical Study of the Safety and Blood Levels of a Human Monoclonal Antibody (2217LS) Against Lyme Disease Bacteria in Healthy People
This is a research study of the investigational drug 2217LS in healthy volunteers. Investigational means 2217LS is a new drug that has not been approved for the treatment of any disease.
- Trial name
- NCT04863287
- Testing
- 2217LS, 0.9% Sodium Chloride (NaCl)
- Where
- United States
- Volunteers
- 44 people, healthy volunteers welcome
- Sponsor
- MassBiologics
Covid19
USEFULNESS of Topic Ivermectin and Carrageenan to Prevent Contagion of Covid 19
Estimation of the prevalence and contagiousness of undocumented novel coronavirus infections is critical for understanding the overall prevalence and pandemic potential of this disease.
- Trial name
- IVERCAR (NCT04425850)
- Testing
- Iota carrageenan nasal spray and Ivermectin oral drops (used as buccal drops)
- Where
- Argentina
- Volunteers
- 229 people, healthy volunteers welcome
- Sponsor
- Eurnekian Public Hospital
Healthy Endurance Athlet, Inactive People
Effects of Exercise Timing on Sleep Quality
Modern lifestyles are marked by a prevalence of sedentary behaviors and physical inactivity, which have been linked to numerous adverse health effects.
- Trial name
- SLEEPCORE (NCT07322276)
- Testing
- Aerobic Exercise
- Where
- France
- Volunteers
- 42 people, healthy volunteers welcome
- Sponsor
- Centre Hospitalier Universitaire de Saint Etienne
COVID-19
Safety and Immunogenicity Study of an Inactivated SARS-CoV-2 Vaccine for Preventing Against COVID-19
This study is a randomized, double-blinded, and placebo-controlled phase Ia/IIa clinical trial of the Inactivated SARS-CoV-2 Vaccine to evaluate the safety and immunogenicity of the vaccine in healthy people aged 18~59 Years.
- Trial name
- NCT04412538
- Testing
- Low dosage Inactivated SARS-CoV-2 Vaccine on a 0- and 28-day schedule, Low dosage Inactivated SARS-CoV-2 Vaccine on a 0- and 14-day schedule, Medium dosage Inactivated SARS-CoV-2 Vaccine on a 0- and 28-day schedule
- Where
- China
- Volunteers
- 942 people, healthy volunteers welcome
- Sponsor
- Institute of Medical Biology, Chinese Academy of Medical Sciences
Healthy
Pharmacodynamic Effects, Safety and Tolerability of Cilobradine, to Healthy Male and Female Volunteers, With an Intra-individual Comparison to Moxifloxacin in a Subset of Volunteers
Incidence of visual phenomena, heart rate at rest, safety (with particular emphasis on QT analysis of ECGs), and pharmacokinetic parameters
- Trial name
- NCT02264015
- Testing
- Cilobradine, low, film-coated tablets, Cilobradine, high, film-coated tablets, Moxifloxacin, film-coated tablets
- Volunteers
- 125 people, healthy volunteers welcome
- Sponsor
- Boehringer Ingelheim
Scleroderma
Empirical Comparative Study of Variation Blood Level Antibody Vitamin D at Scleroderma (SSc) Patients Compared Healthy Peoples
The aim is to find the presence of anti vitamin D antibodies in scleroderma patients and compare with control. A second goal is anti vitamin D levels in serum of scleroderma patients in relation to the clinical manifestations of…
- Trial name
- SSc (NCT01553890)
- Testing
- Blood sample
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Meir Medical Center
Constipation
Efficacy Evaluation of Probiotic Product on Bowel Habits in Healthy Subjects
The objective of this study is to evaluate if consumption of fermented milk containing Lactobacillus casei strain Shirota has an impact on stool consistency, stool frequency, constipation-related symptoms, and quality of life in…
- Trial name
- NCT01375712
- Testing
- Fermented milk containing Lactobacillus casei strain Shirota
- Where
- Germany
- Volunteers
- 238 people, healthy volunteers welcome
- Sponsor
- Yakult Honsha Co., LTD
Healthy Volunteers
A Study of LY2605541 and Insulin Lispro Mixture in Healthy Participants
The main purpose of this study is to evaluate how the body absorbs and removes LY2605541, insulin lispro, and a mixture of both from the blood. The study has two parts. Participants may enroll in only one part.
- Trial name
- NCT01871493
- Testing
- LY2605541, Insulin Lispro
- Where
- Singapore
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Eli Lilly and Company
COVID-19
Immunogenicity and Safety Study of One Booster Dose of Trivalent COVID-19 Vaccine (Vero Cell), Inactivated
This is a randomized, double-blind, active-controlled phase Ⅲ clinical trial.The purpose of this study is to evaluate the immunogenicity and safety of one booster dose of trivalent COVID-19 vaccine (vero cell), inactivated…
- Trial name
- NCT05433272
- Testing
- Trivalent COVID-19 Vaccine (Vero Cell), Inactivated, Prototype Strain, Delta Strain and Omicron Strain, COVID-19 Vaccine (Vero Cell), Inactivated
- Where
- Colombia
- Volunteers
- 1,400 people, healthy volunteers welcome
- Sponsor
- Sinovac Biotech (Colombia) S.A.S.
Deglutition Disorders
Design and Development of a Functional Plant-based Beverage Formulated According to the Main Nutritional Guides for Early Elderly Requirements to Improve Nutritional Status and Immunity for the Early Elderly People to Get Well-healthy Ageing
Populations around the world are aging and this demographic transition will impact almost every aspect of society. Furthermore, the COVID-19 pandemic has highlighted the seriousness of gaps in policies, systems and services.
- Trial name
- IMMUGOLD (NCT06445309)
- Testing
- Sensory test of functional plant-based drink
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- University Rovira i Virgili
Dementia, Alzheimer Disease
The Healthy Patterns Sleep Study
The Healthy Patterns Study intervention is a home-based activity intervention designed to improve symptoms of circadian rhythm disorders (CRD) and quality of life (QOL) in home-dwelling persons with dementia.
- Conditions
- Dementia, Alzheimer Disease, Circadian Rhythm Disorders, Circadian Rhythm Sleep Disorder
- Trial name
- NCT03682185
- Testing
- Attention-Control Condition, Timed Activity Intervention
- Where
- United States
- Volunteers
- 421 people, healthy volunteers welcome
- Sponsor
- University of Pennsylvania
Hemiparesis Proprioceptive Disorders Gait, Hemiplegic, Healthy Individual, Comparative Study
Lower Extremity Proprioception Sensory and Functionality in Hemiparetic
The loss of sensorial feedback causes gait impairment in hemiparesis. The studies show that proprioceptive impairment of knee is related to falling in these patients.
- Trial name
- NCT05062187
- Testing
- Proprioseption in hemiparetics
- Where
- Turkey (Türkiye)
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Istanbul Aydın University
Insulin Resistance
Vitamin D Supplementation and Glycemic Outcomes
The investigators examined the effect of vitamin D supplementation on glucose homeostasis and metabolic markers in healthy normal weight and overweight young subjects and healthy normal-weight and overweight elderly subjects…
- Trial name
- NCT02942732
- Testing
- cholecalciferol (Euro-Pharm International, Canada)
- Volunteers
- 180 people, healthy volunteers welcome
- Sponsor
- Université d'Auvergne
Healthy People Programs
Boxing Training, Physical-functional Fitness and Cognitive Performance in Older Adults
The aim of the study is to evaluate and to compare the effects of two exercise regimes (Boxing Training -BT and Multicomponent Training -MT) and 12 weeks of follow-up on cognitive health status, physical-functional fitness, and…
- Trial name
- Boxe4Ageing (NCT05826314)
- Testing
- Boxing training, Exercise
- Where
- Portugal
- Volunteers
- 75 people, healthy volunteers welcome
- Sponsor
- Universidade do Porto
Vagus Nerve Stimulations
Comparison of the Acute Effects of Auricular Vagus Nerve Stimulation and Deep Breathing Exercise
The goal of this clinical trial is to investigate whether vagus stimulation and breathing exercises are more effective in healthy adults.
- Trial name
- NCT06740032
- Testing
- Transcutaneous vagus nerve stimulation, Deep breath exercise
- Where
- Turkey (Türkiye)
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Istanbul Gelisim University
Quadrivalent Influenza Virus Vaccine
Safety and Immunogenicity Study of Quadrivalent Influenza Virus Vaccine in Healthy People Aged Years 3-60
This study evaluates the safety and immunogenicity of the quadrivalent influenza virus vaccine in healthy people aged years 3-60.Subjects will be randomly divided into 3 groups,receiving the test vaccine, commercially available…
- Trial name
- NCT02806804
- Testing
- one dose test vaccine, one dose commercially available trivalent influenza vaccine, One dose of Quadrivalent Influenza Virus Vaccine
- Volunteers
- 2,400 people, healthy volunteers welcome
- Sponsor
- Beijing Chaoyang District Centre for Disease Control and Prevention
Cryotherapy Effect
Acute Effects of Cryotherapy Duration in Healthy Individuals
The study will investigate the acute effects of cryotherapy duration on shoulder muscle strength, flexibility, endurance and dynamic balance in healthy individuals.
- Trial name
- NCT05355584
- Testing
- Cryotherapy application
- Where
- Turkey (Türkiye)
- Volunteers
- 75 people, healthy volunteers welcome
- Sponsor
- Burcu Camcıoğlu Yılmaz
Human Immunodeficiency Virus Type 1 (HIV-1)
Bioequivalence Study of Individual Atazanavir and Cobicistat Compared With Atazanavir in Fixed-dose Combination With Cobicistat
The purpose of the study is to compare the pharmacokinetics and bioequivalence of atazanavir in a fixed-dose combination with cobicistat with that of atazanavir coadministered with cobicistat as single agents.
- Trial name
- Atazanavir (NCT01837719)
- Testing
- Atazanavir, Cobicistat, Atazanavir/Cobicistat FDC
- Where
- United States
- Volunteers
- 64 people, healthy volunteers welcome
- Sponsor
- Bristol-Myers Squibb
Healthy Volunteers, Dyslipidaemia
A Study to Look at How Safe a New Medicine (NNC0491-6075) is in Healthy People and in Participants With High Levels of Fat in the Blood
The study is testing a new study medicine to treat people with high levels of fat in the blood. The main aim of the study is to see if the new study medicine is safe and how it works in the body.
- Trial name
- NCT05979428
- Testing
- NNC0491-6075
- Where
- United States
- Volunteers
- 106 people, healthy volunteers welcome
- Sponsor
- Novo Nordisk A/S
Exercise, Healthy Participants
Inter- and Intraindividual Variability of the Acute Glucose Response to Exercise in Healthy Adults and People Living With Type 1 Diabetes: A Cross-over Replicate Trial
The goal of this clinical trial is to investigate if blood glucose responses are similar between and within individuals in response to standardized exercise in adults with and without Type 1 diabetes.
- Conditions
- Exercise, Healthy Participants, Glucose Variability, Type 1 Diabetes (T1D)
- Trial name
- NCT07209930
- Testing
- Exercise, Rest
- Where
- Ireland
- Volunteers
- 24 people, healthy volunteers welcome
- Sponsor
- University College Dublin