Clinical trials: Healthy Postmenopausal Women
Pharmacology, Clinical
Bioequivalence Study: 2 mg Estradiol Valerate (EV) and 3 mg Dienogest (DNG) Without and With Levomefolate Calcium
Investigation of the bioequivalence (BE) of Estradiol Valerate (EV) and Dienogest (DNG) after administration of one film-coated tablet containing 2 mg Estradiol Valerate, 3 mg Dienogest and 0.451 mg Levomefolate calcium as…
- Trial name
- NCT00941057
- Testing
- BAY 98-7079, Estradiolvalerate (EV) / Dienogest (DNG) / Levomefolate calcium, BAY 86-5027,Estradiolvalerate(EV) / Dienogest (DNG), BAY 86-7660,levomefolate calcium
- Where
- Germany
- Volunteers
- 43 people, healthy volunteers welcome
- Sponsor
- Bayer
Healthy, no Evidence of Disease, Obesity
Time Restricted Diet in Obese or Overweight Pre or Postmenopausal Participants
The purpose of this study is to study the relationships between obesity, hormones and menopausal status, and breast cancer. The researchers would like to study whether a type of nutritional intervention, called a time-restricted…
- Trial name
- NCT02154984
- Testing
- behavioral dietary intervention, telephone-based intervention, laboratory biomarker analysis
- Where
- United States
- Volunteers
- 45 people, healthy volunteers welcome
- Sponsor
- Northwestern University
Drug Interactions
Microgynon Riociguat Drug Interaction Study in Healthy Postmenopausal Women
Physicians might be concerned that Adempas may have a metabolic interaction with oral contraceptives (OC) that could decrease the contraceptive efficacy of the OC.
- Trial name
- NCT02159326
- Testing
- Microgynon, Riociguat (Adempas,BAY63-2521)
- Where
- Germany
- Volunteers
- 31 people, healthy volunteers welcome
- Sponsor
- Bayer
Osteoporosis, Postmenopausal
A Multiple-Dose Study to Evaluate Skin Irritation and Sensitization of Teriparatide Administered Transdermally in Healthy Postmenopausal Women
This study is a Phase 1, multi-center, 2-part, subject- and investigator-blind, randomized, placebo-controlled, multiple dose study of transdermal teriparatide (80-µg dose) in healthy postmenopausal women.
- Trial name
- NCT01250145
- Testing
- LY333334
- Where
- 5 sites in United States, Germany and 1 more
- Volunteers
- 251 people, healthy volunteers welcome
- Sponsor
- Eli Lilly and Company
Healthy, Postmenopausal Women
Dried Plums and Chronic Disease Markers
This study evaluates whether the consumption of California dried plums can be beneficial to your health. Previous studies using dried plums have shown beneficial effects on bone and cardiovascular health.
- Trial name
- NCT02950402
- Testing
- Two Dried Plums per day, Six Dried Plums per day
- Volunteers
- 27 people, healthy volunteers welcome
- Sponsor
- University of California, Davis
Healthy Postmenopausal Women, Absorption
A Clinical Study to Evaluate the Absorption, Metabolism, and Excretion of Oral [14C]GS1-144 in Healthy Postmenopausal Female Participants
This is a single-center, non-randomized, open-label, single-dose clinical PK study in healthy postmenopausal female participants.
- Conditions
- Healthy Postmenopausal Women, Absorption, Metabolism, Excretion
- Trial name
- NCT07537231
- Testing
- [14C]GS1-144
- Where
- China
- Volunteers
- 6 people, healthy volunteers welcome
- Sponsor
- Changchun GeneScience Pharmaceutical Co., Ltd.
Postmenopause
Study Evaluating Premarin and Bazedoxifene Potential Interaction
The purpose of this study is to evaluate the pharmacokinetics (absorption, distribution, breakdown and elimination in the body) of a single dose of bazedoxifene (BZA) 20 mg tablet when administered together with multiple doses of…
- Trial name
- NCT00745173
- Testing
- Premarin
- Where
- United States
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Wyeth is now a wholly owned subsidiary of Pfizer
Healthy
Role of Endogenous Estrogen in Growth-Hormone Regulation in Postmenopausal Women
Participants are being asked to take part in this research study to learn why growth hormone(GH) levels decline when estrogen production falls at the time of menopause.
- Trial name
- NCT01186796
- Testing
- Fulvestrant
- Where
- United States
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Mayo Clinic
Menopause
Study Evaluating Bazedoxifene/Conjugated Estrogens Combinations In Healthy Postmenopausal Women
Bazedoxifene/Conjugated Estrogens (BZA/CE) is an investigational drug that is being developed for treatment of menopause. The purpose of this trial is to compare a new manufacturing process for making BZA/CE to the current…
- Trial name
- NCT00464789
- Testing
- Bazedoxifene/Conjugated Estrogens 20 mg/0.625 mg tablet
- Volunteers
- healthy volunteers welcome
- Sponsor
- Wyeth is now a wholly owned subsidiary of Pfizer
Osteopenia
A First-in-human Study Evaluating AMG 167 in Healthy Men and Postmenopausal Women
The primary objective of this study is to determine the safety and tolerability of AMG 167 following a single dose subcutaneous (SC) or intravenous (IV) administration in healthy men and postmenopausal women.
- Trial name
- NCT00902356
- Testing
- AMG 167
- Volunteers
- 69 people, healthy volunteers welcome
- Sponsor
- Amgen
Osteoporosis
Biological Bone Markers and Hydrolyzed Collagen Supplement in Menopausal Healthy Women
Preliminary scientific studies, in both animals and humans suggest that oral consumption of hydrolyzed collagen acts on the bone remodeling process by stimulating the activity of osteoblasts responsible for bone formation while…
- Trial name
- NCT01293045
- Testing
- hydrolyzed collagen, wheat protein
- Where
- France
- Volunteers
- 44 people, healthy volunteers welcome
- Sponsor
- Nealth Sarl
Food-effect
Effect of Food on the Bioavailability of 30 mg Estetrol (E4) Tablet in Healthy Postmenopausal Female Volunteers
Assessment of the effect of a high fat meal on the quantity in blood of a female sex hormone called estetrol (E4). The study also aims at determining how subject tolerate the study drug and how safe it is for them.
- Trial name
- NCT03798197
- Testing
- 30 mg estetrol (E4)
- Where
- Bulgaria
- Volunteers
- 28 people, healthy volunteers welcome
- Sponsor
- Donesta Bioscience
Postmenopause
A Study of the Effect of Estrogen on Estrogen Receptor Biomarkers in Healthy Postmenopausal Women (0000-094)(COMPLETED)
This study will develop a model for the assessment of successful activation/engagement of estrogen receptor beta using salivary biomarkers.
- Trial name
- NCT00799708
- Testing
- Comparator: Estrace
- Volunteers
- 27 people, healthy volunteers welcome
- Sponsor
- Merck Sharp & Dohme LLC
Healthy, Nursing Caries
The Effect of Reflexology on Sleep Quality and Fatigue in Postmenopausal Women
Introduction: This study was conducted to determine the effect of reflexology on sleep quality and fatigue in postmenopausal women.
- Trial name
- NCT04467645
- Testing
- reflexology
- Where
- Turkey (Türkiye)
- Volunteers
- 72 people, healthy volunteers welcome
- Sponsor
- Dicle University
Postmenopausal Symptoms
A Clinical Study to Evaluate the Effects of Estrogen in Healthy Postmenopausal Women
The purpose of this study is to examine the effect of two different dose levels of estrogen or placebo in healthy postmenopausal women by measuring the changes in hormone levels and examining the changes in the uterine lining…
- Trial name
- NCT00820664
- Testing
- Comparator: Estrace 0.5 mg, Comparator: Estrace 2 mg
- Volunteers
- 29 people, healthy volunteers welcome
- Sponsor
- Merck Sharp & Dohme LLC
Breast Cancer
IH636 Grape Seed Extract in Preventing Breast Cancer in Postmenopausal Women at Risk of Developing Breast Cancer
RATIONALE: Chemoprevention is the use of certain drugs to keep cancer from forming, growing, or coming back. The use of IH636 grape seed extract may prevent breast cancer.
- Trial name
- NCT00100893
- Testing
- IH636 grape seed proanthocyanidin extract
- Where
- United States
- Volunteers
- 37 people, healthy volunteers welcome
- Sponsor
- City of Hope Medical Center
Healthy, Postmenopausal
AZD1981 Bioavailability Study of Intravenous (IV) and Oral Formulations
The primary objective is to investigate the pharmacokinetics of AZD1981 given in different formulations and to measure renal clearance
- Conditions
- Healthy, Postmenopausal, Surgically Sterile Women
- Trial name
- NCT00918398
- Testing
- AZD1981
- Where
- Sweden
- Volunteers
- 14 people, healthy volunteers welcome
- Sponsor
- AstraZeneca
Osteoporosis
A Study to Estimate the Effect of Formulation on the Relative Absorption of SB-751689 Administered to Healthy Women
This study will examine the effects of formulation on the relative bioavailability of SB-751689 (400 mg) administered to healthy postmenopausal women.
- Trial name
- NCT00540878
- Testing
- SB-751689 oral tablets (400 mg)
- Where
- United States
- Volunteers
- 25 people, healthy volunteers welcome
- Sponsor
- GlaxoSmithKline
Mammographic Breast Density
Effect of Aspirin on Mammogram Density in Healthy Postmenopausal Women With a Moderate or High Level of Breast Density
RATIONALE: Aspirin may be effective in reducing breast density in healthy postmenopausal women with a moderate or high level of breast density.
- Trial name
- NCT00470561
- Testing
- Aspirin
- Where
- United States
- Volunteers
- 144 people, healthy volunteers welcome
- Sponsor
- Fred Hutchinson Cancer Center
Myocardial Infarction, Stroke
Women's Health Initiative Strong and Healthy Study
The WHISH trial applies state-of-the science behavioral principles and currently available technologies to deliver a physical activity intervention without face-to-face contact to ~25,000 older U.S. women expected to consent.
- Conditions
- Myocardial Infarction, Stroke, Cardiovascular Mortality, Hip Fractures
- Trial name
- WHISH (NCT02425345)
- Testing
- Physical Activity
- Volunteers
- 49,331 people, healthy volunteers welcome
- Sponsor
- Fred Hutchinson Cancer Center