Clinical trials: Healthy Volunteer Study
Healthy Volunteers
A Study of Multiple Oral Doses of IX-01 in Healthy Male Subjects
The purpose of this study is to investigate the safety and tolerability of IX-01 after multiple doses, and to determine the PK of IX-01 and activity of CYP3A4.
- Trial name
- NCT02792647
- Testing
- IX-01
- Where
- United Kingdom
- Volunteers
- 24 people, healthy volunteers welcome
- Sponsor
- Ixchelsis Limited
Healthy
Influence of Telmisartan and Lacidipine, Combined or Alone, on QT Interval in Healthy Volunteers
Assessment of the influence of telmisartan, lacidipine and their combination on the QTC interval of the ECG
- Trial name
- NCT02264158
- Testing
- Telmisartan high, Telmisartan low, Lacidipine high
- Volunteers
- 149 people, healthy volunteers welcome
- Sponsor
- Boehringer Ingelheim
Healthy Volunteers
Bioequivalence Study Comparing Linezolid 600 Mg Oral Suspension With 600 Mg Tablet In Chinese Healthy Male Subjects
The purpose of this study is to estimate the bioequivalence comparing Linezolid 600 MG Oral Suspension with 600 MG tablet in Chinese healthy male subjects. This study data will be used to support Linezolid OS NDA in China.
- Trial name
- NCT01055769
- Testing
- Linezolid
- Where
- China
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- Pfizer
Human Gastrointestinal Physiology Data
Modernization of in vivo-in Vitro Oral Bioperformance Prediction and Assessment
In vivo drug dissolution in the gastrointestinal (GI) tract is largely unmeasured. The purpose of this clinical study was to evaluate the in vivo drug dissolution and systemic absorption of the BCS Class IIa drug ibuprofen under…
- Trial name
- NCT02806869
- Testing
- Single dose of ibuprofen (800 mg tablet), Pulmocare, two 8.0 oz (236.6 mL) cans
- Where
- United States
- Volunteers
- 48 people, healthy volunteers welcome
- Sponsor
- University of Michigan
Meningococcal Immunisation (Healthy Volunteers)
Study to Evaluate the Immune Response After a Booster Dose of a Quadrivalent Meningococcal (MenACYW) Conjugate Vaccine When Administered Alone or Concomitantly With a Licensed Meningococcal Serogroup B Vaccine, in Participants Who Received Primary Quadrivalent Meningococcal Conjugate Vaccine (MCV4)
Primary Objective: To demonstrate the vaccine seroresponse sufficiency of meningococcal serogroups A, C, Y, and W following the administration of a booster dose of meningococcal Polysaccharide (Serogroups A, C, Y and W) Tetanus…
- Trial name
- NCT04084769
- Testing
- Meningococcal polysaccharide (serogroups A, C, Y, and W) tetanus toxoid Conjugate vaccine MenACYW Conjugate vaccine, Meningococcal Group B vaccine (Trumenba®), Meningococcal group B vaccine (Bexsero®)
- Where
- 30 sites in United States, Puerto Rico
- Volunteers
- 570 people, healthy volunteers welcome
- Sponsor
- Sanofi Pasteur, a Sanofi Company
Atopic Dermatitis
A Clinical Study of HRS-8797 in Healthy Participants
The purpose of this phase I study is to evaluate the safety, tolerability, pharmacokinetics and pharmacodynamics of HRS-8797 in healthy participants.
- Trial name
- NCT07698756
- Testing
- HRS-8797
- Where
- China
- Volunteers
- 74 people, healthy volunteers welcome
- Sponsor
- Chengdu Suncadia Medicine Co., Ltd.
Pharmacokinetics of Alefacept
A Study of Pharmacokinetics and Safety of Alefacept in Caucasian and Japanese Healthy Volunteers
The objective of this study is to compare the pharmacokinetic and pharmacodynamic properties and safety profile of alefacept in Caucasian and Japanese healthy subjects
- Trial name
- NCT00653822
- Testing
- alefacept
- Where
- United States
- Volunteers
- 75 people, healthy volunteers welcome
- Sponsor
- Astellas Pharma Inc
Ovulation Inhibition
Ovulation Inhibition of Two 4-phasic Oral Contraceptive Regimens
The aim of the study is to investigate the ovulation inhibition of two 4-phasic oral contraceptive regimens.
- Trial name
- NCT00805415
- Testing
- EV/DNG (Qlaira, BAY86-5027, SH T00658K), EV/DNG (SH T00658L)
- Where
- 2 sites in Germany, Netherlands
- Volunteers
- 209 people, healthy volunteers welcome
- Sponsor
- Bayer
Healthy
A Study to Assess the Drug-Drug Interaction Between VX-787 and Oseltamivir
The purpose of this study is to investigate the drug-drug interaction between VX-787 and oseltamivir, when co-administered at steady-state in healthy participants.
- Trial name
- NCT02262715
- Testing
- VX-787, Oseltamivir
- Where
- Belgium
- Volunteers
- 38 people, healthy volunteers welcome
- Sponsor
- Janssen Infectious Diseases BVBA
Healthy Volunteer
Effect of Food on the Pharmacokinetics of Apremilast (CC-10004) in Healthy Adults
The purpose of the study is to evaluate the effects of a high fat meal on the pharmacokinetics of a single dose of 30 mg apremilast in healthy adults.
- Trial name
- NCT01634178
- Testing
- Apremilast
- Where
- United States
- Volunteers
- 46 people, healthy volunteers welcome
- Sponsor
- Amgen
Rheumatoid Arthritis, Psoriasis
A Study of Experimental Medication BMS-986251, Taken by Mouth, in Healthy Participants and Patients With Average to Very Serious Psoriasis
The purpose of this study is to investigate experimental medication BMS-986251 taken by mouth in healthy patients and patients with average to very serious Psoriasis (a condition characterized by itchy, dry skin with a scaly…
- Conditions
- Rheumatoid Arthritis, Psoriasis, Ankylosing Spondylitis, Inflammatory Bowel Diseases
- Trial name
- NCT03329885
- Testing
- BMS-986251
- Where
- Netherlands
- Volunteers
- 38 people, healthy volunteers welcome
- Sponsor
- Bristol-Myers Squibb
Gluten Intolerance
Development of a Celiac Safe Food Additive
The goal of this clinical trial was to investigate if intestinal deamidation of gliadin from wheat bread could be hindered by adding a E304i/zinc additive.
- Trial name
- NCT06005376
- Testing
- Breakfast rolls consisting of wheat flour with and without a E304i/zinc additive
- Where
- Sweden
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- Chalmers University of Technology
Diabetes Mellitus, Type 2
A Clinical Study to Evaluate the Safety and the Pharmacokinetics of UI068 in Healthy Adult Volunteers Under Fed Conditions
This study was open-label, randomized, fed, single-dose, 2-groups, 2 periods, crossover designe to compare the safety and pharmacokinetics of UI068 and co-administration of UIC202205 and UIC202206.
- Trial name
- NCT06141590
- Testing
- administration of UI068, administration of UIC202205, UIC202206
- Where
- South Korea
- Volunteers
- 35 people, healthy volunteers welcome
- Sponsor
- Korea United Pharm. Inc.
Healthy Volunteer
Study of SAGE-904 Using a Ketamine Challenge to Evaluate Electrophysiology, Safety, Tolerability, and Pharmacokinetics in Healthy Participants
The primary purpose of this study is to determine functional target engagement of SAGE-904 using electrophysiological paradigms before and after ketamine administration.
- Trial name
- NCT05049343
- Testing
- SAGE-904, Ketamine
- Where
- United States
- Volunteers
- 22 people, healthy volunteers welcome
- Sponsor
- Supernus Pharmaceuticals, Inc.
Healthy Volunteer
A Study of Aleglitazar in Combination With Ibuprofen in Healthy Volunteers
This randomized, double-blind, placebo-controlled, parallel group study will investigate the safety and tolerability, and the effect of aleglitazar in combination with ibuprofen on renal function, renin-angiotensin system and…
- Trial name
- NCT01188317
- Testing
- aleglitazar, ibuprofen
- Where
- United States
- Volunteers
- 44 people, healthy volunteers welcome
- Sponsor
- Hoffmann-La Roche
Mild to Moderate Asthma
Study of PRA-216 in Healthy Participants and Participants With Mild-to-Moderate Asthma
Phase 1 of this study will consist of 2 parts Part 1 will evaluate the safety, tolerability, pharmacokinetics and immunogenicity of PRA-216 in healthy volunteers through single ascending dose administered by either intravenous…
- Trial name
- NCT07245368
- Testing
- PRA-216
- Where
- 8 sites in Australia, New Zealand
- Volunteers
- 96 people, healthy volunteers welcome
- Sponsor
- Prana Therapies Inc
Fed
Bioequivalence Study of Olanzapine Orally Disintegrating Tablets, 5 mg Under Fed Condition
The purpose of this study is to compare the single oral dose bioequivalence of olanzapine 5 mg OD tablets with Zyprexa Zydis 5 mg tablets under fed conditions and to monitor adverse events and ensure safety of subjects.
- Trial name
- NCT01503450
- Testing
- Olanzapine OD Tablets 5 mg
- Where
- India
- Volunteers
- 26 people, healthy volunteers welcome
- Sponsor
- Dr. Reddy's Laboratories Limited
Healthy Participants
A First-In-Human Study of the Study Medicine, Called PF-07291177, in Healthy Adult Participants
The purpose of the study is to learn about the safety, tolerability (the extent to which side effects can be tolerated), and plasma pharmacokinetics (PK) (PK helps us understand how the drug is changed and eliminated from body…
- Trial name
- NCT05434091
- Testing
- PF-07291177
- Volunteers
- healthy volunteers welcome
- Sponsor
- Pfizer
Healthy, Prediabetic State
Effect of a Collagen Hydrolysate on Postprandial Blood Glucose Profile in Prediabetic and Healthy Subjects
To investigate the effect of two different dosages collagen hydrolysate (CH) on postprandial blood glucose and insulin profile in prediabetic and normo-glycaemic subjects.This will be investigated in a cross-over randomized…
- Trial name
- NCT05887791
- Testing
- Collagen hydrolysate
- Where
- Germany
- Volunteers
- 16 people, healthy volunteers welcome
- Sponsor
- Rousselot BVBA
Healthy
Safety and Tolerability Comparison of Immediate and Controlled Release Formulations of Ecopipam
Ecopipam hydrochloride (HCl) is an investigational drug being studied for several possible diseases. To date, all clinical studies have been done using the ecopipam immediate release (IR) tablet.
- Trial name
- NCT01408394
- Testing
- Ecopipam immediate release form, 90 mg controlled release form, 180 mg controlled release form
- Where
- United States
- Volunteers
- 16 people, healthy volunteers welcome
- Sponsor
- Emalex Biosciences Inc.
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