Clinical trials: Healthy Volunteer Subjects
Epilepsy, Healthy Volunteer
Dose Escalation Study to Assess the Safety, Tolerability, Pharmacokinetics And Pharmacodynamics of SIF001 in Healthy Subjects and in Epilepsy Patients
This is a dose escalation study to assess the safety, tolerability, pharmacokinetics and pharmacodynamics of SIF001, a monoclonal antibody with the potential to treat epilespy
- Trial name
- NCT07051629
- Testing
- SIF001
- Where
- 10 sites in United States
- Volunteers
- 88 people, healthy volunteers welcome
- Sponsor
- Suninflam Inc
Healthy Volunteers
A Trial to Compare the Amount of Centanafadine That Enters the Bloodstream for Two Different Formulations of Centanafadine
The purpose of this trial is to assess relative bioavailability of centanafadine (CTN) SR tablet to CTN QD XR capsule in healthy adult participants.
- Trial name
- NCT07465731
- Testing
- Centanafadine SR, Centanafadine QD XR
- Where
- United States
- Volunteers
- 62 people, healthy volunteers welcome
- Sponsor
- Otsuka Pharmaceutical Development & Commercialization, Inc.
Healthy Participants
A Study to Evaluate the Food-Effect of H3B-6527
This study will be conducted to determine the effect of food on the relative bioavailability of H3B-6527 following administration of a H3B-6527 capsule with and without a meal.
- Trial name
- NCT03424577
- Testing
- H3B-6527
- Where
- United States
- Volunteers
- 17 people, healthy volunteers welcome
- Sponsor
- Eisai Inc.
Healthy
The Effects of TMS on Memory-consolidation in Human Primary Visual Cortex
Rapid Transcranial Magnetic Stimulation will be used in order to examine whether the human primary visual cortex is essential to visual memory consolidation.
- Trial name
- NCT00480012
- Testing
- rTMS
- Volunteers
- healthy volunteers welcome
- Sponsor
- Sheba Medical Center
Healthy Volunteer
Drug-drug Interaction Study of Ozanimod With Tyramine to Evaluate the Effect on Pressor Response
The purpose of this study is to evaluate the potential effect of ozanimod on pressor response when co-administered with oral tyramine in healthy adult subjects.
- Trial name
- NCT03694119
- Testing
- Phenelzine, Tyramine, ozanimod
- Where
- United States
- Volunteers
- 92 people, healthy volunteers welcome
- Sponsor
- Celgene
Healthy
Impact of Interdental Brushing on the Evolution of Supra-gingival Bacterial Flora (BACTERIB)
In France, two-thirds of adults over 35 years of age have at least a periodontal disease. The etiology is the accumulation of dental plaque, especially in interdental spaces.
- Trial name
- BACTERIB (NCT03714295)
- Testing
- Use of interdental brushes
- Where
- France
- Volunteers
- 25 people, healthy volunteers welcome
- Sponsor
- Claude Bernard University
Depressive Disorder and Anxiety Disorders
A Study To Investigate Effects Of GSK561679 On Brain Activation During Emotional Processing In Healthy Volunteers
This study will be conducted in healthy volunteers to investigate the effect of single dose GSK561679 on the changes of brain activation, as it compares to an active comparator, lorazepam.
- Trial name
- NCT00513565
- Testing
- single dose
- Where
- United States
- Volunteers
- 22 people, healthy volunteers welcome
- Sponsor
- GlaxoSmithKline
Healthy
Clinical Evaluation of the Phototoxic Potential of Xenaderm Ointment
The product is being tested to see if exposure to light causes toxic reactions on the skin.
- Trial name
- NCT00644917
- Testing
- Xenaderm
- Volunteers
- 38 people, healthy volunteers welcome
- Sponsor
- Healthpoint
Hemodynamics, Biosensors
Validation of Ballistocardiographic Biosensors and Other Hemodynamic Measures for Healthy Subjects
Ballistocardiographic (BCG) biosensors reflecting the patients' current state is established. There are few studies documenting BCG biosensors efficacy, effectiveness, and efficiency.
- Conditions
- Hemodynamics, Biosensors, Cardiac
- Trial name
- NCT04585568
- Testing
- Biosensors
- Where
- Norway
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- Oslo University Hospital
Healthy
Effect of Ketanserin, Olanzapine, and Lorazepam After LSD Administration on the Acute Response to LSD in Healthy Subjects
The main objective of this study is to determine whether administration of ketanserin (40 mg), olanzapine (10 mg), and lorazepam (2 mg) after administration of LSD (150 µg) attenuates and shortens the subjective LSD response (any…
- Trial name
- LBL (NCT05964647)
- Testing
- LSD (150 µg) + ketanserin (40 mg), LSD (150 µg) + olanzapine (10 mg), LSD (150 µg) + lorazepam (2 mg)
- Where
- Switzerland
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- University Hospital, Basel, Switzerland
Type 2 Diabetes
A Pharmacokinetic Study Comparing the 14028 Injection and TRULICITY® in Healthy Chinese Subjects
To evaluate the pharmacokinetics similarity between the 14028 injection produced by Sunshine Lake Pharma Co., Ltd. and dulaglutide injection (TRULICITY®) produced by Eli Lilly and Company for single dose in healthy male subjects…
- Trial name
- NCT05459285
- Testing
- 14028 injection, dulaglutide injection
- Where
- China
- Volunteers
- 68 people, healthy volunteers welcome
- Sponsor
- Sunshine Lake Pharma Co., Ltd.
Healthy Volunteers
Study of AC0058TA in Healthy Male and Female Subjects
AC0058TA is a small molecule compound that potently, selectively and irreversibly inhibits Bruton's tyrosine kinase (BTK) phosphorylation and downstream signals, resulting in inhibition of inflammatory cytokine production in…
- Trial name
- NCT02847325
- Testing
- AC0058TA
- Where
- United States
- Volunteers
- 56 people, healthy volunteers welcome
- Sponsor
- ACEA Therapeutics, Inc.
Healthy Subjects (HS)
Evaluation of Safety, Tolerability, Pharmacokinetics and Pharmacodynamics of BT-114143 Injection in Healthy Subjects
This study is a single-center, randomized, double-blind, placebo-controlled, single dose escalation design to evaluate the safety, tolerability, and pharmacokinetic characteristics of BT-114143 Injection.
- Trial name
- NCT07169240
- Testing
- BT-114143
- Where
- China
- Volunteers
- 84 people, healthy volunteers welcome
- Sponsor
- ScinnoHub Pharmaceutical Co., Ltd.
Healthy Volunteers
Study to Determine the Pharmacokinetic (PK) Bioequivalence of ABP 501 and Adalimumab (Humira®) in Healthy Adult Japanese Participants
The primary objective of this study is to determine the bioequivalence of ABP 501 (subcutaneous [SC] injection) compared to adalimumab (SC injection) as assessed principally by the area under the serum concentration-time curve…
- Trial name
- NCT05995691
- Testing
- ABP 501, Adalimumab
- Volunteers
- 179 people, healthy volunteers welcome
- Sponsor
- Amgen
Healthy Subjects
A Food Effect Study to Evaluate the Pharmacokinetics of ASP1517
The objective of this study is to evaluate the effect of food on the pharmacokinetics of a single oral dose of ASP1517 in non-elderly healthy adult male subjects.
- Trial name
- NCT02805374
- Testing
- ASP1517
- Where
- Japan
- Volunteers
- 16 people, healthy volunteers welcome
- Sponsor
- Astellas Pharma Inc
Depression
Assessment of the Effect of Sertaline on the Specific Binding of 123-I MZINT in Healthy Subjects
The overall purpose of this project is to evaluate the effect of sertraline administration on the binding of 123-I mZINT in 10 healthy subjects.
- Trial name
- mZINT (NCT00470925)
- Testing
- 123-I MZINT injection and SPECT imaging
- Where
- United States
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Institute for Neurodegenerative Disorders
Healthy Adult Subjects
Single Ascending Oral Dose Phase 1 Study of ID110521156 in Healthy Adult Subjects
The purpose of this study is to evaluate the safety, tolerability and pharmacokinetics of single oral doses of ID110521156 in healthy adult subjects. This is the first clinical study of ID110521156.
- Trial name
- NCT06063291
- Testing
- ID110521156
- Where
- South Korea
- Volunteers
- 36 people, healthy volunteers welcome
- Sponsor
- IlDong Pharmaceutical Co Ltd
Drug Interactions, Human Immunodeficiency Virus
Pharmacokinetic Interactions Between an Herbal Medicine (African Potato) and Antiretroviral Agents (Lopinavir/Ritonavir)
The study is being conducted to evaluate whether African potato, an herbal medicine, can be used together with anti-HIV medicines without affecting the amounts of the anti-HIV medicines in the blood.
- Trial name
- AP6142 (NCT01227590)
- Testing
- Kaletra (lopinavir/ritonavir), African Potato (hypoxis obtusa)
- Where
- United States
- Volunteers
- 18 people, healthy volunteers welcome
- Sponsor
- University of California, San Francisco
Healthy Volunteers
Study to Compare the Pharmacokinetics of Mycophenolate Mofetil Metabolites From Four Tablet Formulations in Healthy Participants
This is a single center, randomized, open label, 4-treatment, 4-period, 4-sequence, 4-way crossover study to compare the pharmacokinetics of mycophenolate mofetil (MMF) metabolites from 4 tablet formulations in healthy…
- Trial name
- NCT02981290
- Testing
- Renodapt, Mycept, Cellmune
- Where
- New Zealand
- Volunteers
- 32 people, healthy volunteers welcome
- Sponsor
- Hoffmann-La Roche
Healthy
An Ascending Multiple Dose Study of CD101 IV in Healthy Subjects
A multiple ascending dose study to evaluate the safety, tolerability, and pharmacokinetics of CD101 Injection in Healthy Subjects.
- Trial name
- NCT02551549
- Testing
- CD101 IV
- Where
- United States
- Volunteers
- 24 people, healthy volunteers welcome
- Sponsor
- Cidara Therapeutics Inc., a subsidiary of Merck & Co., Inc. (Rahway, New Jersey USA)
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