Clinical trials: Healthy Young Subjects
Contraception
Relative Bioavailability, Transdermally Administered EE and GSD, 3 Applications Sites
Influence of different application sites on the blood levels after administration of a fertility control patch
- Trial name
- NCT01083264
- Testing
- Gestodene/EE Patch (BAY86-5016)
- Where
- Germany
- Volunteers
- 43 people
- Sponsor
- Bayer
Cholesterol
MD Ezetimibe Cyclosporine Interaction (0653-057)
Study to determine the effect of multiple oral doses of ezetimibe on the pharmacokinetics of a single oral dose cyclosporine in young healthy males and females.
- Trial name
- NCT00653276
- Testing
- ezetimibe, Comparator: cyclosporine
- Volunteers
- 13 people, healthy volunteers welcome
- Sponsor
- Organon and Co
Healthy
Effect of Ketoconazole on Biliary Excretion of AZD0837
This is an explorative study and the scientific question to be investigated is if the biliary excretion of AZD0837 and its metabolites AR-H069927XX and AR-H067637XX are affected by co-administration with ketoconazole
- Trial name
- NCT00812344
- Testing
- AZD0837, Ketoconazole
- Where
- Sweden
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- AstraZeneca
Diabetes, Healthy
Comparison of the Effect of Liraglutide in Young Versus Elderly Healthy Volunteers
This trial is conducted in Europe. The aim of this trial is to compare the exposure of liraglutide in young versus elderly healthy subjects.
- Trial name
- NCT01507337
- Testing
- liraglutide
- Where
- Germany
- Volunteers
- 32 people, healthy volunteers welcome
- Sponsor
- Novo Nordisk A/S
Hyperlipidemia
Gender Dependent Difference in Lipemia After 6 x OFTT in Young Healthy Subjects
The investigators wanted to study the postprandial lipemia after six oral fat tolerance test with varying amounts of saturated fat in young healthy subjects.
- Trial name
- NCT02506920
- Testing
- Six different types of fat in a meal in random order
- Volunteers
- 14 people, healthy volunteers welcome
- Sponsor
- Herning Hospital
Healthy Subjects
Circulating Levels of Irisin in Healthy Young Subjects
Irisin, a newly discovered myokine induced in exercise, has potential effects in stimulating adipose tissue browning, fighting obesity and diabetes.
- Trial name
- IRISSAS (NCT01986530)
- Testing
- Boost, Aerobic exercise
- Where
- Greece
- Volunteers
- 122 people, healthy volunteers welcome
- Sponsor
- 424 General Military Hospital
Healthy Young, Electric Stimulation Therapy
Pulsed Current Versus Russian Current Effects in Healthy Young Subjects.
Low frequency pulsed current (PC) and medium frequency alternating current (Russian current - RC, 2.5 kHz) have been largely studied due to their clinical use.
- Trial name
- NCT03796117
- Testing
- Pulsed current, Russian Current
- Where
- Brazil
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Federal University of Rio Grande do Sul
Epilepsy
Single-dose and Steady-state Pharmacokinetics of BIA 2-093 and Its Metabolites
The purpose of this study is to determine the effects of age on the pharmacokinetic profile of BIA 2-093 and its active metabolites.
- Trial name
- NCT02172755
- Testing
- BIA 2-093
- Where
- Germany
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Bial - Portela C S.A.
Healthy, Health Adult Subjects
Effect of Magnesium Supplementation on Sleep Quality and Cognitive Function in Saudi Adults
The goal of this clinical trial was to evaluate whether magnesium citrate supplementation improved sleep quality and cognitive function in healthy Saudi adults. It also assessed the effects of magnesium on selected blood markers.
- Conditions
- Healthy, Health Adult Subjects, Healthy Participants, Healthy Adult Participants
- Trial name
- NCT07515417
- Testing
- Magnesium 400Mg
- Where
- Saudi Arabia
- Volunteers
- 41 people
- Sponsor
- Umm Al-Qura University
Binge Drinking, Liver Injury
Metabolic Changes in Healthy Subjects with Acute Binge Drink
The goal of this double-blinded, randomized trial is to investigate the effects of acute binge drinking on liver function, liver fat content, and lipid metabolism in healthy young subjects.
- Conditions
- Binge Drinking, Liver Injury, Hepatic Steatosis
- Trial name
- MeABD (NCT06298318)
- Testing
- Vodka, water
- Where
- China
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Zhejiang Chinese Medical University
Alzheimer Disease
Study Evaluating PAZ-417 in Healthy Young/Elderly
This study is to evaluate the safety and tolerability of single, ascending doses of PAZ-417 in healthy young and healthy elderly subjects.
- Trial name
- NCT00366288
- Testing
- PAZ-417
- Where
- United States
- Volunteers
- 56 people, healthy volunteers welcome
- Sponsor
- Wyeth is now a wholly owned subsidiary of Pfizer
Schizophrenia
Pharmacokinetic Properties of Various Modified Release Tablet Formulations of Lu AF11167
The purpose of this study is to investigate the pharmacokinetic (PK) properties of various modified release tablet formulations of Lu AF11167 (Part A) and to investigate the pharmacokinetic (PK) properties of a modified release…
- Trial name
- NCT02260830
- Testing
- Lu AF11167
- Where
- United Kingdom
- Volunteers
- 28 people, healthy volunteers welcome
- Sponsor
- H. Lundbeck A/S
Parkinson's Disease
Effect of Stimulus Rate on Cognitive and Motor Activity in Young Subjects, Elderly Subjects, and Patients With Parkinson's Disease
The purpose of this study is to investigate how changes in the brain associated with Parkinson's disease influence the control of motor and thinking speed.
- Trial name
- NCT00026598
- Where
- United States
- Volunteers
- 90 people, healthy volunteers welcome
- Sponsor
- National Institute of Neurological Disorders and Stroke (NINDS)
Schizophrenia, Cognition Disorders
The Effect of Nicotine on Arousal, Cognition and Social Cognition in Young and Elderly Healthy Subjects.
This study in young and elderly healthy subjects will investigate the effect of nicotine on arousal, cognitive task and social cognition after acute dose administration.
- Trial name
- NCT01181934
- Testing
- A643 (nicotine)
- Volunteers
- 32 people, healthy volunteers welcome
- Sponsor
- Janssen Pharmaceutica N.V., Belgium
Cardiovascular Diseases
Safety of Single Intravenous Administration of S95010 in Human Healthy Volunteers
The purpose of the study is to assess, the safety and tolerability of single ascending doses of S 95010 and to assess the pharmacokinetics (PK) of S 95010.
- Trial name
- NCT03494712
- Testing
- S 95010
- Where
- Belgium
- Volunteers
- 49 people, healthy volunteers welcome
- Sponsor
- Institut de Recherches Internationales Servier
Healthy
Study of the Choroidal and Retinal Thickness in Relation to Axial Length.
The aim of the study is the non-invasive morphological evaluation of the choroid and the retina in relation to the length of the eyeball in healthy, young man and women.
- Trial name
- CHORAL (NCT03377075)
- Testing
- AL measurement, OCT
- Where
- Hungary
- Volunteers
- 55 people, healthy volunteers welcome
- Sponsor
- Semmelweis University
Bioavailability of Ipragliflozin, Healthy Subjects
Absolute Bioavailability Study With Ipragliflozin
A study to assess the absolute bioavailability of ipragliflozin in healthy subjects.
- Trial name
- NCT01611428
- Testing
- Ipragliflozin
- Where
- United Kingdom
- Volunteers
- 14 people, healthy volunteers welcome
- Sponsor
- Astellas Pharma Europe B.V.
Parkinson Disease
Pharmacokinetics of BIA 9-1067 and Its Metabolites in Healthy Male Elderly Subjects and in Healthy Male Young Subjects
The purpose of this study is to determine the effects of age on the pharmacokinetic (PK) profile of BIA 9-1067 and its metabolites.
- Trial name
- NCT02092168
- Testing
- BIA 9-1067
- Where
- France
- Volunteers
- 24 people, healthy volunteers welcome
- Sponsor
- Bial - Portela C S.A.
Chemotherapy-Induced Nausea and Vomiting
A Bioequivalence Study of 3 Formulations of Ondansetron in Healthy Adults (0869-095)(COMPLETED)
This study will assess the bioequivalence of a Merck clinical trial formulation of ondansetron compared to a U.S. and non-U.S. marketed formulation of ondansetron.
- Trial name
- NCT00971633
- Testing
- Comparator: Treatment A (Zofran, ondansetron), Comparator: Treatment B (Zofran, ondansetron), Comparator: Treatment C (Zofran, ondansetron)
- Volunteers
- 12 people, healthy volunteers welcome
- Sponsor
- Merck Sharp & Dohme LLC
Healthy Volunteers, Pharmacokinetics of Mirabegron
A Clinical Study to Assess the Effect on Pharmacokinetics of Dosing Mirabegron (YM178) and Solifenacin Simultaneously
This study investigates whether mirabegron (YM178) has an effect on the pharmacokinetics of solifenacin and whether solifenacin has an effect on the pharmacokinetics of mirabegron.
- Trial name
- NCT01297192
- Testing
- solifenacin succinate, mirabegron
- Where
- France
- Volunteers
- 41 people, healthy volunteers welcome
- Sponsor
- Astellas Pharma Inc