Clinical trials: Healthy Young Volunteers, active
Healthy Volunteers, Low Back Pain
Effects of Blood Flow Restriction Exercises on Lumbar Muscle Endurance and Balance in Healthy Young Adults
This study aims to examine the effects of blood flow restriction (BFR) exercises on back muscle endurance and balance in healthy young adults.
- Conditions
- Healthy Volunteers, Low Back Pain, Postural Balance, Muscle Fatigue
- Trial name
- BFR-LUMBEX (NCT07182812)
- Testing
- Blood Flow Restriction Sit-to-Stand Exercise, Sit-to-Stand Exercise without Blood Flow Restriction
- Where
- Turkey (Türkiye)
- Volunteers
- 70 people, healthy volunteers welcome
- Sponsor
- Mehmet Akif Guler
Healthy Volunteers, Vibration; Adverse Effect
Acute Effects of Smartphone-Delivered Local Vibration on Hand Sensorimotor Performance
This study investigates the acute effects of smartphone-delivered local vibration on hand sensorimotor performance in healthy young adults.
- Trial name
- SmartVib (NCT07521228)
- Testing
- Smartphone Local Vibration at 80 Hz, Smartphone Local Vibration at 150 Hz, Smartphone Local Vibration at 220 Hz
- Where
- Turkey (Türkiye)
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- Acibadem University
Influenza -Like Illness, Influenza (Healthy Volunteers)
Mucosal and Systemic Immunity Correlates of Protection Against Influenza in Young Children, Aged 2-5 Years (MUSIC-Flu)
Title: Mucosal and systemic immunity correlates of protection against influenza in young children (MUSIC-Flu). The goal of this observational study is to better understand how immune responses in the blood and mucosa are linked…
- Trial name
- MUSIC-Flu (NCT07861854)
- Where
- South Africa
- Volunteers
- 150 people, healthy volunteers welcome
- Sponsor
- National Institute for Communicable Diseases, South Africa
Healthy Subjects or Volunteers
Hydrogen-Rich Water and Resting Metabolism in Young Adults
The H2REST trial is a randomized, double-blind, placebo-controlled crossover study investigating the acute effects of a single dose of hydrogen-rich water (HRW) on resting metabolism in healthy young adults.
- Trial name
- H2REST (NCT07098221)
- Testing
- Molecular Hydrogen
- Volunteers
- 24 people, healthy volunteers welcome
- Sponsor
- University of Novi Sad
Healthy Adults Aged 50 and Over
BrainLive Connect: Volunteer Training Programme
The goal of this mixed method clinical trial is to evaluate whether BrainLive Coach training can enhance knowledge, skills, and wellbeing among young old volunteers.
- Trial name
- NCT07544875
- Testing
- BrainLive Coach training, Other intervention
- Where
- Hong Kong
- Volunteers
- 180 people, healthy volunteers welcome
- Sponsor
- The University of Hong Kong
Vegetarian Diet, Elderly
Effect of Vegetarien Diet on Protein Digestibility in Young and Elderly Volunteers
Plant proteins are usually less digestible than animal proteins, but they may benefit gut health through effects on the microbiome.
- Conditions
- Vegetarian Diet, Elderly, Young Healthy Adults
- Trial name
- VEGAA (NCT07521189)
- Testing
- Postprandial test, Amino acid bioavailability
- Where
- France
- Volunteers
- 48 people, healthy volunteers welcome
- Sponsor
- Institut National de Recherche pour l'Agriculture, l'Alimentation et l'Environnement
Muscle Wasting
The Effect of Repeated Whole-body NMES Sessions With or Without Protein Intake on Muscle Protein Synthesis During 3 Days of Bed Rest in Healthy Young Volunteers
The goal of this clinical trial is to examine the effect of whole-body electrostimulation with protein intake on muscle protein synthesis, muscle mass and function during bed rest in healthy young adults (18-35 years).
- Trial name
- SPRINT (NCT07062562)
- Testing
- NMES, Protein bolus (20g), Standard nutrition
- Where
- Netherlands
- Volunteers
- 42 people, healthy volunteers welcome
- Sponsor
- Wageningen University
Healthy Volunteers
Effect of Transcranial Near InfraRed Light on Cerebral Function in Young and Healthy Older Subjects: a FMRI Study (TIROC)
Numerous studies have shown that the extra-cranial application of near infrared light (λ=600-1000nm) (also called transcranial photobiomodulation or tPBM), has a positive impact on brain function in both humans and experimental…
- Trial name
- TIROC (NCT05845216)
- Testing
- ACTIVE Transcranial photobiomodulation (tPBM)
- Where
- France
- Volunteers
- 64 people, healthy volunteers welcome
- Sponsor
- University Hospital, Grenoble
Pharmacokinetic Study in Healthy Volunteers
A Comparison of Fisetin Kinetics in Young and Old Adults
This study investigates the differences in the kinetic parameters of fisetin in two cohorts of healthy volunteers: Cohort 1) volunteers aged 18-30 years (n = 40) Cohort 2) volunteers aged 65 years or older (n = 40) The purpose of…
- Trial name
- FISEKIN-1 (NCT06796374)
- Testing
- Fisetin - Fasted condition, Fisetin - Fed condition
- Where
- Germany
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- University Medicine Greifswald
Healthy Volunteers
Weight Gain Prevention in Adolescents and Young Adults
The investigators believe they key to effective prevention of obesity is early identification of individuals at high risk of excess weight gain and proactive implementation of a comprehensive approach including lifestyle-based…
- Trial name
- NCT06905626
- Testing
- Qsymia 7.5 miligrams (mg)-46 mg Extended Release Capsule
- Where
- United States
- Volunteers
- 140 people, healthy volunteers welcome
- Sponsor
- University of Minnesota
Muscle Strength Recovery, Endurance
Efficacy of LN18178 in Improving Muscle Strength, Aerobic Capacity and Body Composition in Healthy Young Males
The Purpose of the study is to evaluate the efficacy of LN18178 in improving muscle strength, aerobic capacity and body composition in healthy young males.
- Conditions
- Muscle Strength Recovery, Endurance, Healthy Human Volunteers
- Trial name
- NCT07092722
- Testing
- LN18178
- Volunteers
- 120 people, healthy volunteers welcome
- Sponsor
- GENCOR Lifestage Solutions
Epstein Barr Virus (EBV) Infection
Phase 1 Trial to Evaluate Safety and Immunogenicity of MVA-BN-EBV in Healthy Young Adults
Phase 1, single-center, randomized, placebo-controlled, double-blind clinical trial. Participants (N = 15) will receive a 2-dose schedule (1 vaccination on day 1 and day 28) randomized, receiving either MVA-BN-EBV (n = 12) or…
- Trial name
- NCT07888088
- Testing
- MVA-BN-EBV
- Where
- United States
- Volunteers
- 15 people, healthy volunteers welcome
- Sponsor
- Bavarian Nordic
Healthy Volunteers
The Effect of Two Different Exercise Programs in Young Sailors
This study aims to investigate the effects of an 8-week structured land-based exercise program on hiking endurance, core endurance, muscle activation, balance, and motor competence in young sailors.
- Trial name
- NCT07097116
- Testing
- Hiking Bench Exercise Program, Structured Land-Based Exercise Program
- Where
- Turkey (Türkiye)
- Volunteers
- 26 people, healthy volunteers welcome
- Sponsor
- Istinye University
Healthy Adult Male and Female Volunteers
Effects of Exercise Frequency on Muscle Size and Strength in Healthy, Untrained Young Adults
Resistance training (RT) is important for building and maintaining healthy muscles. An exercise frequency called "exercise snacks" involves short bursts of exercise throughout the day (~5-15 minutes), but no studies have examined…
- Trial name
- FREQ (NCT07760597)
- Testing
- 10 sessions per week of resistance training, Two sessions per week of resistance training
- Where
- Canada
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Cameron Mitchell
Depression in Adolescence, Antidepressant Activity in Healthy Volunteers
Fluoxetine and Understanding Social Experiences
Adolescence is a critical developmental period marked by significant social, cognitive, and emotional changes. Unfortunately, it is also a time when the risk of depression and anxiety rises dramatically.
- Conditions
- Depression in Adolescence, Antidepressant Activity in Healthy Volunteers, Healthy Adult Participants
- Trial name
- FUSE (NCT07456501)
- Testing
- Fluoxetine
- Where
- United Kingdom
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- University of Oxford
Healthy
Effect of a Nutritional Supplement on Muscle Recovery
The aim is to develop a food supplement drink that supports muscle health by combining specific fatty acids, which can positively affect metabolic and inflammation processes that are important for muscle health.
- Trial name
- RECOVER (NCT07586839)
- Testing
- Control drink, Vegan supplement containing caprylic acid and omega-3 fatty acids
- Where
- Netherlands
- Volunteers
- 28 people, healthy volunteers welcome
- Sponsor
- Wageningen University
Healthy Human Volunteers, Youth Resilience
"One All" to Get it RYT (Resilient Young Tribal Adults)
:The study is designed to introduce a curriculum "One All", organised around the sport, Ultimate Frisbee, as a way to improve mental health resilience.
- Trial name
- NCT06474260
- Testing
- "One All" Intervention
- Where
- 2 sites in India
- Volunteers
- 240 people, healthy volunteers welcome
- Sponsor
- University of Pittsburgh
Type 1 Diabetes Mellitus, Glucokinase-Maturity Onset Diabetes of the Young (GCK-MODY)
Cardiometabolic Benefit of Reducing Iatrogenic Hyperinsulinemia Using Insulin Adjunctive Therapy in Type 1 Diabetes
This study aims to understand the heart and blood sugar health benefits of using an adjunctive therapy to lower high insulin levels in people with type 1 diabetes.
- Conditions
- Type 1 Diabetes Mellitus, Glucokinase-Maturity Onset Diabetes of the Young (GCK-MODY), MODY2 Diabetes, Healthy Volunteer
- Trial name
- ACT T1D (NCT06609356)
- Testing
- Study Visit 1, Study Visit 2, Sodium Glucose Co-transporter 2 (SGLT2) Inhibitor
- Where
- United States
- Volunteers
- 27 people, healthy volunteers welcome
- Sponsor
- Vanderbilt University Medical Center
Healthy Volunteers - Male and Female
Acute Effects of a Single-Session Body Awareness Intervention on Cortical Activity and Interoceptive Accuracy
This study will examine the immediate (acute) effects of a single, 30-minute body awareness session on brain activity and interoceptive accuracy in healthy young adults aged 18-25.
- Trial name
- BBAT-EEG (NCT07736365)
- Testing
- Basic Body Awareness Therapy Intervention
- Volunteers
- 84 people, healthy volunteers welcome
- Sponsor
- Ertugrul Deniz Kose
Healthy Volunteers
A Study of RSV-HMPV Bivalent Vaccine VXB-241 in Older Adults
The main purposes of this study are to assess the safety, reactogenicity and immunogenicity of 4 dose levels of the bivalent combination Respiratory Syncytial Virus (RSV) / human Metapneumovirus (hMPV) vaccine candidate VXB-241…
- Trial name
- NCT06556147
- Testing
- VXB-241 60 mcg (Low Dose), VXB-241 120 mcg (Medium Dose), VXB-241 240 mcg (Medium-high Dose)
- Where
- 4 sites in Australia
- Volunteers
- 144 people, healthy volunteers welcome
- Sponsor
- Sanofi