Clinical trials: Hearing
Hearing Loss
School Screening and Telemedicine Specialty Referral to Address Childhood Hearing Loss in Rural Alaska
The prevalence of childhood hearing loss in rural Alaska is disproportionately high and predominately infection-related. With preventive screenings and access to health care, much of childhood hearing loss is preventable.
- Trial name
- NCT05593484
- Testing
- Standard Referral, Specialty Telemedicine Access for Referrals (STAR)
- Where
- United States
- Volunteers
- 8,060 people, healthy volunteers welcome
- Sponsor
- University of Arkansas
Cochlear Implant, Children
Effect of Perceptual Training and Phonetic Placement Therapy in Children With Cochlear Implant
Background: Children with cochlear implants often continue to exhibit speech sound and intelligibility difficulties despite improved auditory access.
- Conditions
- Cochlear Implant, Children, Speech Sound Disorder
- Trial name
- NCT07613034
- Testing
- Phonetic placement therapy, perceptual training
- Where
- Pakistan
- Volunteers
- 12 people, healthy volunteers welcome
- Sponsor
- Riphah International University
Central Auditory Processing Disorder, Traumatic Brain Injury
Central Auditory Processing Disorders Associated With Blast Exposure
The incidence of central auditory dysfunction in war fighters who are exposed to high-explosive blasts while serving in combat have not been clearly determined.
- Conditions
- Central Auditory Processing Disorder, Traumatic Brain Injury, Hearing Loss
- Trial name
- NCT00554801
- Testing
- Audiological testing
- Where
- United States
- Volunteers
- 84 people, healthy volunteers welcome
- Sponsor
- VA Office of Research and Development
Auditory Perceptual Disorders, Age-related Hearing Loss
Objective Measurement of Hearing Aid Benefit
Hearing loss is a critical health concern in the rapidly aging population, affecting approximately 22 million older individuals in the United States.
- Trial name
- NCT04431622
- Testing
- Hearing aid amplification algorithms
- Volunteers
- healthy volunteers welcome
- Sponsor
- University of Maryland, College Park
Speech Intelligibility, Hearing Loss, Sensorineural
The Influence of the Individual Auditory-cognitive Need on the Aided Benefit Using Different Feature Settings
The goal of this clinical trial is to optimize hearing aid benefit based on the individual auditory-cognitive need using different hearing aid features in first-time hearing aid users between 45-80 years old with bilateral Phonak…
- Trial name
- NCT06420037
- Testing
- Hearing aid feature adjustment (frequency compression) of the following hearing aids: Phonak Audéo Paradise/Lumity 70, Hearing aid feature adjustment (noise reduction) of the following hearing aids: Phonak Audéo Paradise/Lumity 70, Cognitive screening and vision screening
- Where
- Belgium
- Volunteers
- 32 people, healthy volunteers welcome
- Sponsor
- University Ghent
Hearing Loss, GJB2, Cis Regulation, DFNB1
Development Cellular Models of the Ear and Nose to Study the Mechanisms of Hearing
Development of cells culturesissued from Nose and Ear to study auditory mecanisms. Study of the cis-Modulation of the gene GJB2 for the patients with early presbycusis to identify the genetic cause of hearing loss.
- Trial name
- CMAG (NCT04823195)
- Where
- France
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- University Hospital, Brest
Tinnitus
Genetically-informed Behavioral and Cognitive Interventions for the Management of Tinnitus
Psychological and behavioral interventions, such as Cognitive Behavioral Treatment (CBT) and Tinnitus Retraining Therapy (TRT), are commonly applied either alone or in combination for the management of tinnitus but selection of…
- Trial name
- NCT04675112
- Testing
- Cognitive Behavioral Treatment (CBT) and Tinnitus Retraining Therapy (TRT)
- Where
- Greece
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- Gkouskou Kalliopi
Hearing Loss, Cochlear
Otoacoustic Emissions in Different Blood Types
The objective of this study is to examine whether ABO and Rhesus (Rh) blood group systems have an association with distortion product otoacoustic emission (DPOAE) and transient otoacoustic emission (TEOAE) amplitudes with the…
- Trial name
- NCT06326866
- Testing
- Otoacoustic emissions (non-invasive)
- Where
- Turkey (Türkiye)
- Volunteers
- 70 people, healthy volunteers welcome
- Sponsor
- Istanbul University - Cerrahpasa
Hearing Loss, Sensorineural Hearing Loss
Study to Determine the Safety, Tolerability, and Pharmacokinetic Profile of HPN-07 and HPN-07 Plus NAC
This study is a single-center, randomized, placebo-controlled, double-blind, single ascending dose escalation study to determine the safety, tolerability, and PK profile of oral administration of HPN-07 in single doses to…
- Conditions
- Hearing Loss, Sensorineural Hearing Loss, Noise-Induced Hearing Loss
- Trial name
- NCT02259595
- Testing
- HPN-07, NAC
- Where
- United States
- Volunteers
- 32 people, healthy volunteers welcome
- Sponsor
- Otologic Pharmaceutics, Inc.
Bilateral Sensorineural Hearing Loss
Evaluation of Revised Indicatons (ERID) for Cochlear Implant Candidacy for the Adult CMS Population
Purpose: The purpose of this study is 1) to evaluate the safety and efficacy of currently available multichannel cochlear implant systems for newly implanted adults with an indication based on open-set sentence recognition that…
- Trial name
- NCT02075229
- Testing
- Cochlear implant
- Where
- 19 sites in United States
- Volunteers
- 37 people, healthy volunteers welcome
- Sponsor
- American Cochlear Implant Alliance
Hearing Loss
Local Heat-Stress as a Mechanism of Hearing Preservation
This pilot study plans to determine whether or not local heat-stress as a mechanism can help to preserve hearing in adults treated with Cisplatin.
- Trial name
- NCT02872844
- Testing
- ICS AirCal3
- Volunteers
- healthy volunteers welcome
- Sponsor
- University of Nebraska
Tinnitus
Investigating EEG as a Biomarker for Tinnitus Improvement After Bimodal Stimulation
The aim of the proposed study is to investigate the use of resting-state Electroencephalogram (EEG)-Based Brain Entropy (EBDBE) and auditory brainstem responses (ABR) as an objective measure of tinnitus improvement following the…
- Trial name
- NCT07158034
- Testing
- Lenire Device
- Where
- United States
- Volunteers
- 10 people, healthy volunteers welcome
- Sponsor
- University of Minnesota
Hearing Loss, Gentamicin Adverse Reaction
Auditive and Renal Long Term Outcomes - Risk After Aminoglycoside Therapy in Neonates (AURORA)
Gentamicin, in combination with a beta-lactam antibiotic, is commonly used for treatment of neonatal sepsis. Neonates have a high volume of distribution.
- Conditions
- Hearing Loss, Gentamicin Adverse Reaction, Renal Tubular Disorder
- Trial name
- AURORA (NCT03253614)
- Testing
- Audiometry, Urine biomarkers for renal tubular function, Blood pressure
- Where
- Norway
- Volunteers
- 226 people, healthy volunteers welcome
- Sponsor
- University Hospital of North Norway
Hearing Loss
Auditory Research in Children Living With HIV Exposure-uninfected (ARCHIVE)
To evaluate the association of in utero antiretroviral therapy (ART) exposure and hearing abilities of children who were perinatally HIV-exposed, but HIV-free, stratified by timing of maternal ART initiation.
- Trial name
- ARCHIVE (NCT06635642)
- Testing
- Dichotic Interaural Intensity Difference (DIID) Training
- Volunteers
- healthy volunteers welcome
- Sponsor
- San Diego State University
Hearing Loss, Bilateral or Unilateral, Otitis Media With Effusion in Children
Towards Implementation of Universal Newborn Hearing Screening in Kenya
The goal of this observational study is to learn if smartphone hearing screening devices can help to understand the role of ear infections in hearing loss in infants with HIV exposure.
- Trial name
- mTUNE-R33 (NCT07879326)
- Testing
- Hearing and ear health screening
- Where
- Kenya
- Volunteers
- 400 people, healthy volunteers welcome
- Sponsor
- University of Washington
Hearing Loss, Dizziness
Fall Risk Assessment and Speech Intelligibility Enhancement Using In-ear Device
The purpose of this study is to develop and validate methods to use hearing aids equipped with embedded sensors and artificial intelligence to assist in the assessment of fall risk and in the implementation of interventions aimed…
- Conditions
- Hearing Loss, Dizziness, Vertigo, Fall Related Injury Risk
- Trial name
- NCT05365646
- Testing
- Hearing aids equipped with motion sensing abilities
- Where
- United States
- Volunteers
- 350 people, healthy volunteers welcome
- Sponsor
- Stanford University
Down Syndrome
An Online Health Tool About Down Syndrome: Down Syndrome Clinic to You
The investigators conducted a national two-arm, randomized controlled trial of caregivers of individuals with DS to assess the efficacy of DSC2U in assuring adherence to evidence-based guidelines.
- Trial name
- DSC2U (NCT04227197)
- Testing
- Down Syndrome Clinic to You (DSC2U)
- Where
- United States
- Volunteers
- 281 people, healthy volunteers welcome
- Sponsor
- Massachusetts General Hospital
Hearing Loss, Sensorineural, Hearing Loss, Bilateral
Investigating Hearing Aid Frequency Response Curves
Internal research on the manufacturer's hearing aid products has idenitfied areas in which the investigators can improve the hearing aid frequency response curve.
- Trial name
- NCT05521308
- Testing
- Hearing Aid - Standard Curve, Hearing Aid - Variation #1, Hearing Aid - Variation #2
- Where
- Canada
- Volunteers
- 33 people, healthy volunteers welcome
- Sponsor
- Sonova AG
Healthy Volunteer
Normal Values in Hearing and Balance Testing
Background: Researchers at the National Institutes of Health give many tests of hearing and balance. These tests can help detect problems that affect hearing or balance.
- Trial name
- NCT01629108
- Where
- United States
- Volunteers
- 500 people, healthy volunteers welcome
- Sponsor
- National Institute on Deafness and Other Communication Disorders (NIDCD)
Hearing Loss, ASD
Diagnostic Instruments for Autism in Deaf Children Study
The trial is in three stages and will translate and validate screening and assessment instruments for use with deaf children. The first stage is modifying the screening and assessment instruments (ADI-R and ADOS-2) for use with…
- Trial name
- DIADS (NCT01932515)
- Testing
- A revised screening instrument for use in Deaf children
- Where
- United Kingdom
- Volunteers
- 325 people, healthy volunteers welcome
- Sponsor
- Leeds and York Partnership NHS Foundation Trust