Clinical trials: Hearing, active
Senile Deadness
Efficacy and Safety of rTMS Combined With HA in the Treatment of Cognitive Decline in Aged Related Hearing Loss
This study is a real-world interventional trial enrolling 189 participants: older adults with age-related hearing loss not using hearing aids (ARHL-nonHA), those using hearing aids (ARHL-HA), and those with normal hearing (HC).
- Trial name
- NCT07389213
- Testing
- repetitive Transcranial Magnetic Stimulation (rTMS)
- Where
- China
- Volunteers
- 189 people, healthy volunteers welcome
- Sponsor
- Sun Yat-Sen Memorial Hospital of Sun Yat-Sen University
Tinnitus, Misophonia
Mindfulness Application Effects on Mental Health Symptoms in Children With Severe Tinnitus and Misophonia
Children with "bothersome" tinnitus and misophonia have elevated anxiety and depression symptoms. The mainstay therapy for adults and children with these disorders is cognitive behavioral therapy (CBT).
- Trial name
- NCT06493825
- Where
- United States
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- University of Colorado, Denver
Cognitive Disorder, Deafness
EARLY DETECTION OF DEAFNESS IN A MEMORY CENTER
Age-related hearing loss (ARHL), like neurodegenerative diseases, appears insidiously with age. As major public health issues, they are nonetheless under-diagnosed because the presence of one can hinder the objectification of the…
- Trial name
- CogAudio (NCT06088953)
- Testing
- VRB test
- Where
- France
- Volunteers
- 200 people
- Sponsor
- University Hospital, Lille
Hearing Loss, Cognitive Impairment, Mild
ENACT Program on Auditory Perception and Function, Cognitive Function and Health-related Quality of Life
Although previous studies indicated that tackling hearing loss may have a secondary benefit in improving cognitive function and delaying the onset of dementia, a more integrated care approach to optimize both hearing and…
- Trial name
- NCT06955494
- Testing
- Empowerment Network for Auditory-Cognitive Training (ENACT) Program, Usual Care
- Where
- Hong Kong
- Volunteers
- 62 people
- Sponsor
- The University of Hong Kong
Trisomy 13 Syndrome, Arthrogryposis Congenita Multiplex With Intestinal Atresia
Palliative Care Needs of Children With Rare Diseases and Their Families
The palliative care needs of family caregivers of children with rare diseases and their children are largely unmet, including the need for support to prepare for future medical decision making.
- Conditions
- Trisomy 13 Syndrome, Arthrogryposis Congenita Multiplex With Intestinal Atresia, Asparagine Synthetase Deficiency, CHARGE Syndrome
- Trial name
- FACE-Rare (NCT06938542)
- Testing
- Family Centered pediatric palliative care for family caregivers of children with rare diseases.
- Where
- United States
- Volunteers
- 480 people, healthy volunteers welcome
- Sponsor
- Children's National Research Institute
Tinnitus
Fudan Tinnitus Doctor for Tinnitus Management
The goal of this clinical trial is to evaluate whether a conversational artificial intelligence-based digital intervention can improve symptoms in adults with chronic subjective tinnitus.
- Trial name
- NCT07558837
- Testing
- Fudan Tinnitus Doctor (FTD) System, Non-conversational Digital Education Program
- Where
- China
- Volunteers
- 256 people
- Sponsor
- Eye & ENT Hospital of Fudan University
Idiopathic Sudden Sensorineural Hearing Loss
Mechanism and Application of Vitamin D in Idiopathic Sudden Sensorineural Hearing Loss
Clinical Trial Protocol: Investigating the Therapeutic Efficacy of Vitamin D in ISSNHL。Core Research Questions Can vitamin D supplementation improve the prognosis of Idiopathic Sudden Sensorineural Hearing Loss (ISSNHL)? What…
- Trial name
- N (NCT07045883)
- Testing
- Vitamin D Supplementation+ standard treatment, standard treatment
- Where
- China
- Volunteers
- 197 people, healthy volunteers welcome
- Sponsor
- Zhongshan Hospital Xiamen University
Ototoxicity, Drug-Induced
Diagnostic of Various Ototoxicity Induced by Cancer Treatment
Visit the clinic once every 2 weeks for checkups and tests The goal of this clinical trial is to learn if systematic hearing tests (eg fonctional assesment, electrophysiology and seric biomarkers) can diagnose hidden hearing loss…
- Trial name
- BIO-OTOTOX (NCT06490029)
- Testing
- Auditory, vestibular and electrophysiological investigations, Biologic investigations; seric proteins
- Where
- France
- Volunteers
- 540 people, healthy volunteers welcome
- Sponsor
- Direction Centrale du Service de Santé des Armées
Hearing Loss, Bilateral
Sentence Shaping - DHH
The proposed research addresses a long-standing and important challenge of improving literacy skills of children who are deaf and hard of hearing, a historically under researched group.
- Trial name
- NCT06860022
- Testing
- Shape Coding
- Where
- United States
- Volunteers
- 30 people
- Sponsor
- Vanderbilt University
Sensorineural Hearing Loss, Hearing Loss
Quantification of Visually Evoked Cortical Potentials in Individuals With Hearing Loss
This research is being done to determine whether a test that measures a "Visual Evoked Potential" can be used in a new way for individuals that have hearing loss.
- Trial name
- NCT05107466
- Testing
- P300 Visually evoked potential
- Where
- United States
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Dartmouth-Hitchcock Medical Center
Hearing Loss
AI Noise Reduction in Phonak Hearing Aids
The purpose of this study is to determine if artificial intelligence- based noise reduction can offer objective improvement in hearing and speech perception for hearing impaired patients.
- Trial name
- NCT06743295
- Testing
- DEEPSONIC™ Deep Sound Optimized Neural Integrated Chip Artificial intelligence-based noise reduction
- Where
- United States
- Volunteers
- 500 people
- Sponsor
- Mayo Clinic
Retinitis Pigmentosa (RP), Usher Syndrome Type 2
Study to Evaluate the Long-Term Safety of Ultevursen in Participants With Retinitis Pigmentosa (RP) Due to Mutations in Exon 13 of the USH2A Gene
The purpose of this Phase 2 Open-label study is to evaluate the long-term safety and tolerability of Ultevursen administered via intravitreal injection (IVT) in participants with Retinitis Pigmentosa due to mutations in exon 13…
- Conditions
- Retinitis Pigmentosa (RP), Usher Syndrome Type 2, Deaf Blind, Retinal Disease
- Trial name
- CAPELLA (NCT07796646)
- Testing
- No intervention, will not receive any active study intervention, Intravitreal Injection of Ultevursen
- Volunteers
- 81 people
- Sponsor
- Laboratoires Thea
Hearing, Healthy
Understanding Speech in Background Noise
The goal of this clinical trial is to establish how speech understanding is affected by background noise in people with normal hearing.
- Conditions
- Hearing, Healthy, Speech Perception
- Trial name
- NCT07822802
- Testing
- Speech filtering, Speech with background noise
- Where
- United States
- Volunteers
- 200 people, healthy volunteers welcome
- Sponsor
- Ohio State University
Auditory Perception
Sound Perception Study of Hearing-impaired People With Hearing Aids
The aim of the ETERNEL project will be to study the influence of the perception of a single sound timbre on the understanding of a complex sound scene in hearing-impaired people with hearing aids.
- Trial name
- ETERNEL (NCT06691087)
- Testing
- Influence of the parameters of the sound timbre on the perception of a sound, Complex sound scene comprehension test, Complex sound scene comprehension test with hearing aids
- Where
- France
- Volunteers
- 75 people, healthy volunteers welcome
- Sponsor
- Institut Pasteur
Conductive Hearing Loss
Wideband Tympanometry as a Non-behavioral Test of the Speech-weighted Middle Ear Transfer Function.
There is a need for a non-behavioral clinical test that provides an assessment of how speech is conducted through the middle ear for the optimization of middle ear implants.
- Trial name
- NCT07557771
- Testing
- Wideband Tympanometry
- Where
- Belgium
- Volunteers
- 45 people, healthy volunteers welcome
- Sponsor
- Universitaire Ziekenhuizen KU Leuven
Pulsatile Tinnitus, Venous Sinus Stenosis
BosSTENT ImpLant to trEat debilitatiNg Pulse-synchronous Tinnitus
This study is evaluating the safety and clinical performance of the BosSTENT, a new stent designed specifically for treating pulse-synchronous tinnitus due to venous sinus stenosis.
- Trial name
- B-SILENT (NCT07070089)
- Testing
- BosSTENT implantation
- Where
- 6 sites in Canada, France
- Volunteers
- 90 people
- Sponsor
- Sonorous NV, Inc
Cochlear Implant Recipients, Hearing Loss, Cochlear
An Investigation to Evaluate Sound Coding Enhancements in Adult Cochlear Implant Recipients
This study will evaluate a range of experimental sound coding strategies that may improve hearing for cochlear implant recipients.
- Trial name
- SONORA-MU (NCT06867380)
- Testing
- Investigational sound coding strategy A, Cochlear default sound coding strategy A, Investigational sound coding strategy B
- Where
- 2 sites in Australia
- Volunteers
- 120 people
- Sponsor
- Cochlear
Retinal Disease, Age-Related Macular Degeneration
Stem Cell Ophthalmology Treatment Study II
This study will evaluate the use of autologous bone marrow derived stem cells (BMSC) for the treatment of retinal and optic nerve damage or disease.
- Conditions
- Retinal Disease, Age-Related Macular Degeneration, Retinitis Pigmentosa, Stargardt Disease
- Trial name
- SCOTS2 (NCT03011541)
- Testing
- Arm 1
- Where
- 4 sites in United States, Austria and 1 more
- Volunteers
- 500 people
- Sponsor
- MD Stem Cells
Cochlear Implantation, Robotics
Robotic-Assisted Versus Manual Electrode Array Insertion
Robotics-assisted electrode insertion overcomes many surgeon-related kinetic limitations such as insertion speed, tremor, drift, and lack of accurate force control.
- Trial name
- NCT06951594
- Testing
- Robotic
- Where
- United States
- Volunteers
- 100 people
- Sponsor
- Bruce J Gantz
Vestibular Schwannoma, Ototoxicity
Radiosurgery Induced Ototoxicity in Patients Treated for a Vestibular Schwannoma
The investigators aim to study the impact of stereotactic radiosurgery, for the treatment of vestibular Schwannoma, on the cochlear, vestibular, gustatory, and facial nerve functions and compare it with a conservatively treated…
- Trial name
- NCT05641441
- Testing
- Stereotactic radiosurgery
- Where
- Switzerland
- Volunteers
- 258 people
- Sponsor
- University Hospital, Geneva