Clinical trials: Hearing Disorder
Sensorineural Hearing Loss
Safety of Autologous Stem Cell Infusion for Children With Acquired Hearing Loss
To determine if autologous human umbilical cord blood infusion in children with acquired hearing loss is safe, feasible, improves inner ear function, audition and language development.
- Trial name
- NCT02038972
- Testing
- Autologous Stem Cells
- Where
- United States
- Volunteers
- 11 people
- Sponsor
- James Baumgartner, MD
Hearing Loss
Benefits of Assistive Listening Device for Speech Intelligibility
Speech intelligibility in noise will be evaluated in adults with moderate to moderate-severe sensorineural hearing loss, using an assistive listening device and hearing aid, and compared to speech intelligibility in noise using…
- Trial name
- NCT05072470
- Testing
- Roger microphone, Phonak Audeo hearing aid
- Where
- United States
- Volunteers
- 10 people
- Sponsor
- Sonova AG
Hearing Loss
Collection and Characterization of Objective Measures to Explore the Specificity of Algorithms
The aim of this descriptive study is to collect and describe the characteristics of objective measures to explore the specificity of algorithms.
- Trial name
- NCT03294681
- Testing
- Objective measures with CSEP
- Where
- 6 sites in Australia, Germany and 1 more
- Volunteers
- 153 people
- Sponsor
- Cochlear
Unilateral Severe to Profound Hearing Loss OR Bilateral Severe to Profound Hearing Loss
Safety, Tolerability and Efficacy for CGF166 in Patients With Unilateral or Bilateral Severe-to-profound Hearing Loss
The goal of the study was to evaluate the safety, tolerability, and the potential ability of CGF166 delivered through IL-infusion to improve hearing.
- Trial name
- NCT02132130
- Testing
- CGF166
- Where
- 4 sites in United States
- Volunteers
- 22 people
- Sponsor
- Novartis Pharmaceuticals
Heart Failure, Arrhythmias, Cardiac
Heart Failure and Sudden Cardiac Death Japan Registry
The purpose of this observational registry is to collect clinical events and outcome data in 4 different study populations (cohorts), with a majority of Japanese subjects, that are at risk of sudden cardiac death (SCD) and heart…
- Conditions
- Heart Failure, Arrhythmias, Cardiac, Sudden Cardiac Death
- Trial name
- HINODE (NCT03185832)
- Testing
- CRT-D, ICD, PM / CRT-P
- Where
- 34 sites in Japan
- Volunteers
- 354 people
- Sponsor
- Boston Scientific Corporation
Hearing Loss, Hearing Loss, Conductive
Cross-sectional Evaluation of the Subjective Performance and Satisfaction With Ponto Sound Processors
The study is a non-interventional, observational, cross-sectional, study on users of Ponto sound processors. The purpose of this study is to evaluate subjectively assessed hearing performance and satisfaction with Oticon…
- Conditions
- Hearing Loss, Hearing Loss, Conductive, Hearing Loss, Unilateral
- Trial name
- BC112 (NCT05356221)
- Testing
- Ponto Sound processor
- Where
- United States
- Volunteers
- 170 people
- Sponsor
- Oticon Medical
Hearing Loss
Comparison of Hearing Aid Fitting Outcomes Between Self-fit and Professional Fit for MDHearing Smart Hearing Aids
Hearing aids are commonly used to help people with hearing loss hear better in daily listening environments. MDHearing Smart hearing aids are designed to use the MDHearing app to adjust hearing aids to each individual's hearing…
- Trial name
- NCT05165121
- Testing
- MDHearing smart hearing aid
- Where
- United States
- Volunteers
- 91 people, healthy volunteers welcome
- Sponsor
- MDHearingAid
Hearing Impairment, Hearing Aid Fitting
Blast Exposed Veterans With Auditory Complaints
The purpose of this study is to study blast-exposed Veterans who report hearing handicap but show normal or near normal results on standard audiometric testing.
- Trial name
- NCT02122458
- Testing
- mild-gain hearing aids with high-frequency emphasis over 6-months
- Where
- 3 sites in United States
- Volunteers
- 363 people, healthy volunteers welcome
- Sponsor
- VA Office of Research and Development
Hearing Loss
The Effect of Low-Level Laser Stimulation on Hearing Thresholds
The purpose of this study is to determine whether low-level laser therapy can improve hearing thresholds in individuals with hearing loss. Subjects will be randomly assigned to a treatment, placebo, or control group.
- Trial name
- NCT01820416
- Testing
- Low-level Laser Therapy
- Where
- United States
- Volunteers
- 35 people
- Sponsor
- University of Iowa
Hearing Loss, Sensorineural Hearing Loss
Non-significant Risk Study of a Cochlear Implant Headpiece
This study aims to evaluate a cochlear implant headpiece.
- Trial name
- NCT05488535
- Testing
- cochlear implant headpiece
- Where
- United States
- Volunteers
- 101 people
- Sponsor
- Advanced Bionics
Anesthesia
the Impact of Noise on Requirements of Anesthetics During General Anesthesia
The investigators hypothesize that the noise level in the operating theatre influences the patients' requirements of anesthetics.
- Trial name
- NCT02534285
- Testing
- hearing protection
- Where
- Germany
- Volunteers
- 100 people
- Sponsor
- Technische Universität Dresden
Temporary Auditory Threshold Shift
Otoprotection With SPI-1005 for Prevention of Temporary Auditory Threshold Shift
Exposure to loud sounds can cause hearing loss. The purpose of this research study is to evaluate potential prevention of temporary changes in hearing that may occur after listening to music through an iPod or personal music…
- Trial name
- NCT01444846
- Testing
- SPI-1005 Low dose, SPI-1005 Middle dose, SPI-1005 High dose
- Where
- United States
- Volunteers
- 83 people, healthy volunteers welcome
- Sponsor
- Sound Pharmaceuticals, Incorporated
Hearing Loss, Noise-Induced
Noise-Induced Hearing Loss-Acute Exposure Treatment
The purpose of this study is to assess the safety and efficacy of zonisamide for the treatment of noise-induced hearing loss in adults.
- Trial name
- PINIHL-AET (NCT04768569)
- Testing
- Zonisamide 100Mg Cap
- Where
- United States
- Volunteers
- 24 people, healthy volunteers welcome
- Sponsor
- Washington University School of Medicine
Tinnitus
Resting-State Neural Connectivity in Patients With Subjective Tinnitus Without Bother
Tinnitus is the occurrence of an auditory sensation without the presence of an acoustic stimulus. Approximately, 50 million people in the United States experience chronic tinnitus and 15 million of these people have bothersome…
- Trial name
- NCT01049828
- Testing
- No intervention
- Where
- United States
- Volunteers
- 20 people
- Sponsor
- Washington University School of Medicine
Hearing Loss, Tinnitus
Progressive Intervention Program for Tinnitus Management
The purpose of this multi-site randomized clinical study is to test a model treatment program in a VA Audiology clinic, to evaluate its efficacy, ease of implementation, and acceptability to audiologists.
- Trial name
- NCT00371436
- Testing
- Progressive Audiologic Tinnitus Management, Usual Care
- Where
- 2 sites in United States
- Volunteers
- 181 people
- Sponsor
- US Department of Veterans Affairs
Tinnitus
Nitrous Oxide Treatment for Tinnitus
Tinnitus is perception of sound without the presence of an external acoustic stimulus. Approximately 50 million Americans experience chronic tinnitus and of these, 10 million have bothersome tinnitus.
- Trial name
- NCT03365011
- Testing
- Nitrous oxide gas for inhalation
- Where
- United States
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Washington University School of Medicine
Hearing Loss
Clinical Applications for Time-Compressed Speech Tests
The purpose of this study is to determine the effects of age-related cognitive changes on hearing aid benefit based on hearing aid compression time constants.
- Trial name
- NCT00371839
- Testing
- Audiological Evaluation
- Volunteers
- 78 people, healthy volunteers welcome
- Sponsor
- US Department of Veterans Affairs
Hearing Loss
Evaluation of a Revised Indication for Determining Adult Cochlear Implant Candidacy
The Sponsor values the progression of hearing healthcare practice and acknowledges a need for re-evaluation of indications for determining adult cochlear implant candidacy.
- Trial name
- NCT01337076
- Testing
- cochlear implant
- Where
- United States
- Volunteers
- 21 people, healthy volunteers welcome
- Sponsor
- Cochlear
Hearing Loss, Conductive, Hearing Loss Mixed
Investigating Hearing With Ponto 3 SuperPower, a Bone Anchored Hearing Aid - Investigating Hear
The study is part of the Post Market Clinical Follow (PMCF) activity. The investigational device is the CE-marked Ponto 3 SuperPower (available on the market since December 2016) already fitted to the subjects, and data is…
- Conditions
- Hearing Loss, Conductive, Hearing Loss Mixed, Hearing Disability, Conductive Hearing Loss
- Trial name
- NCT04803279
- Testing
- Collection of Pure tone thresholds from audiogram measured prior to fitting of Ponto 3 SuperPower, Collection of BC In-situ thresholds from BC In-situ audiogram measured during fitting of Ponto 3 SuperPower, Collection of Aided sound field thresholds measured with the Ponto 3 SuperPower
- Where
- United Kingdom
- Volunteers
- 57 people
- Sponsor
- Oticon Medical
Sensorineural Hearing Loss, Autoimmune Inner Ear Disease
A Clinical Trial of Anakinra for Steroid-Resistant Autoimmune Inner Ear Disease
The purpose of this study is to determine if Anakinra (an interleukin-1 receptor antagonist) can improve hearing thresholds in those patients with Autoimmune Inner Ear Disease (AIED) that did not respond to oral steroid therapy…
- Trial name
- NCT01267994
- Testing
- Anakinra
- Where
- United States
- Volunteers
- 13 people
- Sponsor
- Andrea Vambutas