Clinical trials: Heart; Complications
Erector Spinae Plane Block, Pain Control
Intravenous(IV) vs. Erector Spinae Plane Blocks in Cardiac Surgery
Interfascial plane blocks have been developed for analgesia, among which the erector spinae plane (ESP) has gained popularity. The ESP block has been hypothesized to provide truncal analgesia by spread of local anesthetic into…
- Conditions
- Erector Spinae Plane Block, Pain Control, Post-Operative Pain, Chronic
- Trial name
- NCT04995497
- Testing
- Intravenous Administration of Lidocaine Post Cardiac Surgery, Administration of Lidocaine Post Cardiac Surgery via ESP Catheter
- Where
- United States
- Volunteers
- 70 people
- Sponsor
- Archit Sharma
Symptomatic Irreversible Pulpitis, Symptomatic Irreversible Pulpitis (SIP)
Effect of Audiovisual Distraction on Dental Anxiety and Heart Rate During Root Canal Treatment
Dental anxiety is common among patients undergoing root canal treatment and may negatively affect their experience during dental care.
- Conditions
- Symptomatic Irreversible Pulpitis, Symptomatic Irreversible Pulpitis (SIP), Symptomatic Irreversible Pulpitis and Post Operative Pain, Dental Anxiety
- Trial name
- AV-ENDO (NCT07910513)
- Testing
- Audiovisual Distraction
- Where
- Spain
- Volunteers
- 100 people
- Sponsor
- Ramón Miguéns-Vila
Cardiopulmonary Bypass, Congenital Defects
Aprotinin in Neonates Undergoing Cardiopulmonary Bypass
This is a retrospective chart review study. The purpose of this study is to review our experience at Children's Healthcare of Atlanta in neonates receiving aprotinin.
- Conditions
- Cardiopulmonary Bypass, Congenital Defects, Hemostasis
- Trial name
- NCT00469742
- Where
- United States
- Volunteers
- 290 people
- Sponsor
- Children's Healthcare of Atlanta
Myocardial Injury After Noncardiac Surgery (MINS), Postoperative Complications
Prediction Model for MINS After Major Hepatobiliary Surgery
This multi-center, prospective observational study aims to develop and validate an interpretable prediction model for Myocardial Injury After Noncardiac Surgery (MINS) in patients undergoing major hepatobiliary surgery.
- Conditions
- Myocardial Injury After Noncardiac Surgery (MINS), Postoperative Complications, Liver Neoplasm, Hepatobiliary Diseases
- Trial name
- NCT07335042
- Testing
- Major Hepatobiliary Surgery
- Where
- 6 sites in China
- Volunteers
- 1,800 people
- Sponsor
- Beijing Tsinghua Chang Gung Hospital
Patients Undergoing Coronary Artery Bypass Graft (CABG) Surgery Requiring Extracorporeal Circulation
Role of Mitochondrial Dysfunction in the Occurrence of Acute Kidney Injury (AKI) in Postoperative Cardiac Surgery
Cardiac Surgery and Acute Kidney Failure (AKI) post Surgery: AKI is a frequent complication in the immediate aftermath of cardiac surgery with an incidence varying from 5 to 40%.
- Trial name
- MIT-CEC (NCT04125069)
- Testing
- Coronary Artery Bypass Graft (CABG)
- Where
- France
- Volunteers
- 27 people
- Sponsor
- University Hospital Center of Martinique
Coronary Artery Bypass
Tight Intra-Operative Glucose Control During Coronary Artery Bypass Surgery
Blood glucose levels increase in response to stress, infection or other conditions faced by patients in the hospital. This occurs commonly among patients with known diabetes, but also among non-diabetic hospitalized patients.
- Trial name
- NCT00394303
- Testing
- Intraoperative continuous insulin infusion, Control
- Where
- Israel
- Volunteers
- 1,400 people
- Sponsor
- Rabin Medical Center
Diabetic Cardiomyopathy
Mechanisms Responsible for Cardiac and Skeletal Muscle Energetic Impairment in Diabetes
Diabetes increases the risk of heart failure. This is mainly due to a disease of the blood vessels supplying the heart muscle and/or high blood pressure, but abnormal metabolism may also contribute.
- Trial name
- DDCM (NCT00628056)
- Testing
- Perhexiline
- Where
- United Kingdom
- Volunteers
- 75 people
- Sponsor
- University Hospital Birmingham
Angina Pectoris
Cardioprotective Effects of GLP-1 and Their Mechanisms
Ischaemic heart disease is the most common cause of death in the UK. Glucagon-like peptide-1 (GLP-1) has been demonstrated to protect the heart when it is deprived of blood supply (ischaemia).
- Trial name
- NCT02128022
- Testing
- GLP-1 (7-36) amide, Glibenclamide
- Where
- United Kingdom
- Volunteers
- 32 people
- Sponsor
- Papworth Hospital NHS Foundation Trust
Advanced Heart Failure, Left Ventrucular Assist Device
Neuron Specific Enolase in Ventricular Assist Device Recipients
An observational study of neuron specific enolase, as a marker of reperfusion injury, in LVAD recipients before and following VAD implantation.
- Trial name
- NSE-LVAD (NCT01643551)
- Where
- United States
- Volunteers
- 15 people
- Sponsor
- University of Minnesota
Acute Kidney Injury
Personalized Versus Standard Hydration for Prevention of CI-AKI: a Randomized Trial With Bioimpedance Analysis
The aim of this study was to evaluate, in patients with "lower fluid status" defined by bioimpedance analysis, whether two different protocol of IV isotonic saline infusion are associated with different volume expansion and…
- Trial name
- NCT02225431
- Testing
- sodium chloride infusion
- Where
- Italy
- Volunteers
- 296 people
- Sponsor
- Ospedale Misericordia e Dolce
Acute Kidney Injury
Renal Oxygen Saturation During Off-pump Coronary Artery Bypass Graft Surgery
The purpose of this study is to evaluate changes in renal oxygen saturation (rrSO2) and its relationship with central venous oxygen saturation (cvSO2), cerebral cortical oxygen saturation (rcSO2), and hemodynamic parameters while…
- Trial name
- OPCAB (NCT04679337)
- Where
- South Korea
- Volunteers
- 46 people
- Sponsor
- Yeungnam University College of Medicine
Renal Stone
Basic Hemodynamic Monitoring Reliability During Percutaneous Nephrolithotomy.
This prospective pre and post-quasi-descriptive single group interventional study will be done at urology and nephrology center -Mansoura University during the year 2019, for a 3-month duration, starting 1-2-2019 till 1-4-2019…
- Trial name
- NCT03828175
- Testing
- spinal anesthesia monitoring
- Where
- Egypt
- Volunteers
- 40 people
- Sponsor
- Mansoura University
Heart Transplantation, Chronic Renal Insufficiency
Genetic Predictors of Renal Dysfunction Following Heart Transplantation
Kidney disease is a common problem after heart transplantation. It may be caused by anti-rejection medications such as cyclosporine or tacrolimus.
- Trial name
- NCT01686191
- Where
- United States
- Volunteers
- 300 people
- Sponsor
- University of Colorado, Denver
Heart Failure
Effectiveness of Ultrafiltration in Treating People With Acute Decompensated Heart Failure and Cardiorenal Syndrome (The CARRESS Study)
Heart failure is a serious condition in which the heart's ability to pump blood through the body is impaired, often making a person feel weak or fatigued.
- Trial name
- CARRESS (NCT00608491)
- Testing
- Stepped pharmacologic care, Ultrafiltration
- Where
- 9 sites in United States, Canada
- Volunteers
- 188 people
- Sponsor
- Duke University
Acute Kidney Injury, Congenital Heart Disease
Acute Kidney Injury After Cardiac Surgery on CPB
The purpose of this retrospective study is to determine the incidence and severity of acute kidney injuries (AKI) after heart surgery on cardiopulmonary bypass (CPB) in the pediatric intensive care unit (PICU) in Lausanne…
- Conditions
- Acute Kidney Injury, Congenital Heart Disease, Surgery, CBP
- Trial name
- NCT03513718
- Where
- Switzerland
- Volunteers
- 250 people, healthy volunteers welcome
- Sponsor
- Centre Hospitalier Universitaire Vaudois
Surgical Procedures, Telemedicine
The Risk of Surgical Cancellation in Adult Patients Assessed by Telephone Versus In-person for Scheduled Non-cardiac Elective Surgery.
Telemedicine has been regulated in Colombia since 2006, with applications in anesthesia being explored since 2004 to improve accessibility and reduce costs.
- Conditions
- Surgical Procedures, Telemedicine, Preanesthetic Medication, Preoperative Care
- Trial name
- NCT06693869
- Where
- Colombia
- Volunteers
- 1,176 people
- Sponsor
- Universidad de Antioquia
Kidney Failure
NASPI: N-Acetylcysteine vs. Ascorbic Acid for Prevention of Contrast Induced Nephropathy in Renal Insufficiency Undergoing Coronary Catheterization
The contrast induced nephropathy (CIN) has been known to be associated with significant clinical and economic consequences. Many studies were performed to find the pathophysiology and preventive measures for CIN.
- Trial name
- NCT00356954
- Testing
- N-acetylcystein, ascorbic acid
- Where
- South Korea
- Volunteers
- 250 people
- Sponsor
- Seoul National University Hospital
Arrhythmia, Acute Kidney Injuries
This is an Observational Study That Aims to Demonstrate Postoperative Risk Factors in Pediatric Cardiac Surgery
This retrospective observational study aims to identify risk factors for postoperative complications in children undergoing cardiac surgery at a tertiary hospital in Brazil.
- Conditions
- Arrhythmia, Acute Kidney Injuries, Sepsis, Pneumopathy
- Trial name
- PEDS-CARE (NCT06985082)
- Testing
- THERE IS NOT A INTERVENTION
- Volunteers
- 310 people
- Sponsor
- Instituto de Cardiologia do Rio Grande do Sul
Cardiac Surgery Patient, Postoperative Pain
Effect of Intraoperative Morphine on Postoperative Pain After CABG
Ethics committee approval was obtained for this study, which was planned as a prospective, randomized, controlled, single-center trial to be conducted in patients undergoing coronary artery bypass grafting (CABG) surgery between…
- Conditions
- Cardiac Surgery Patient, Postoperative Pain, Pain After Surgery
- Trial name
- NCT07472959
- Testing
- In this study, morphine administration, which is routinely and frequently used in our operating room for patients undergoing CABG, was applied as an additional intervention
- Where
- Turkey (Türkiye)
- Volunteers
- 60 people
- Sponsor
- Istanbul University - Cerrahpasa
Kidney Diseases, End-Stage Kidney Disease
Major Outcomes With Personalized Dialysate TEMPerature
People with failed kidneys need an artificial kidney machine (called dialysis) to remove toxins and extra fluid from the body. Most patients receive dialysis treatments at a hospital three times a week.
- Conditions
- Kidney Diseases, End-Stage Kidney Disease, Hemodialysis
- Trial name
- MyTEMP (NCT02628366)
- Testing
- Personalized Dialysate Temperature
- Where
- Canada
- Volunteers
- 84 people
- Sponsor
- London Health Sciences Centre Research Institute OR Lawson Research Institute of St. Joseph's
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