Clinical trials: Heart; Surgery, Heart, Functional Disturbance as Result
Atrial Fibrillation, Inflammatory Marker
Red Cell Distribution Width as a Predictor for Post Operative Atrial Fibrillation After Open Heart Surgries
In this study we investigate the correlation between RDW and POAF, as we use the RDW as a predictor for inflammation for prediction of POAF
- Conditions
- Atrial Fibrillation, Inflammatory Marker, Heart; Surgery, Heart, Functional Disturbance as Result
- Trial name
- NCT06286111
- Where
- Egypt
- Volunteers
- 80 people
- Sponsor
- Ain Shams University
Heart; Surgery, Heart, Functional Disturbance as Result
Trial to Compare Different Strategies of Mean Arterial Pressure Management During Cardiopulmonary By-pass
Background: One of the main goals of the Cardiopulmonary By-Pass (CPB) is targeting an adequate Mean Arterial Pressure (MAP), in order to maintain appropriate perfusion pressures in all end-organs during heart surgery.
- Trial name
- MAP (NCT05740397)
- Testing
- Management of mean arterial pressure during cardiopulmonary by-pass in cardiac surgery interventions. The MAP will be mantained in the range of values of each study arm
- Where
- Italy
- Volunteers
- 900 people
- Sponsor
- Azienda Ospedaliera Universitaria Integrata Verona
Heart; Surgery, Heart, Functional Disturbance as Result, Anxiety
Combination of Music and Relaxing Light on the Patient's Anxiety After Cardiac Surgery in the Intensive Care Unit
Cardiac surgery is not trivial. It requires opening the thorax in certain indications: coronary artery bypass grafting, valve replacements or plasties, aortic dissection, etc.
- Conditions
- Heart; Surgery, Heart, Functional Disturbance as Result, Anxiety, Pain, Postoperative, Delirium
- Trial name
- RéaRelax (NCT05178680)
- Testing
- relaxation session combining music and soft light
- Where
- France
- Volunteers
- 110 people
- Sponsor
- Poitiers University Hospital
Heart; Surgery, Heart, Functional Disturbance as Result, Pain, Postoperative
Development of Open Heart Surgery Patient Care Protocol and Its Effect on Post-sternotomy Pain
Open heart surgery method is generally used in the treatment of cardiovascular diseases. Sternotomy is the process of opening the sternum. After sternotomy, individuals experience ongoing pain in the anterior thorax.
- Conditions
- Heart; Surgery, Heart, Functional Disturbance as Result, Pain, Postoperative, Nursing Caries
- Trial name
- NCT05902052
- Testing
- Care Protocol
- Where
- Turkey (Türkiye)
- Volunteers
- 60 people
- Sponsor
- Kutahya Health Sciences University
Heart; Surgery, Heart, Functional Disturbance as Result
Pre-operative Carriage of Respiratory VIRUSes, and Acute Respiratory Distress Syndrome After Heart Surgery
The main objective of our study is to determine whether asymptomatic influenza virus carriage is associated with an increased risk of post-operative Acute Respiratory Distress Syndrome (ARDS) after cardiac surgery.
- Trial name
- VIRUS-ATTAC (NCT04562207)
- Testing
- Screening for respiratory virus infection
- Where
- 5 sites in France
- Volunteers
- 1,256 people
- Sponsor
- Rennes University Hospital
Heart; Surgery, Heart, Functional Disturbance as Result
Evaluation of Damaging Factors to Endothelial Glycocalyx During Heart Surgery.
Evaluation of endothelial glycocalyx damage in on-pump conventional coronary artery bypass surgery using a syndecan-1 (CD138) blood test. The study will be carried out in two stages.
- Trial name
- NCT03491163
- Testing
- Syndecan-1 concentration evaluation
- Where
- Lithuania
- Volunteers
- 147 people
- Sponsor
- Lithuanian University of Health Sciences
Heart; Surgery, Heart, Functional Disturbance as Result, Pediatric ALL
Oblique Versus Transverse Orientation Approach for Internal Jugular Venous Cannulation in Pediatrics
this study aimed to compare oblique versus transverse orientation approach in jugular venous cannulation in term of cannulation success in pediatric heart surgery patients
- Trial name
- NCT05656937
- Testing
- internal jugular venous cannulation
- Where
- Indonesia
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Universitas Indonesia
Left Ventricular Systolic Dysfunction
3D & Speckle Tracking Together as a Marker for Early Outcome in Cardiac Surgery
Patients presenting with Left Ventricle (LV) dysfunction undergoing cardiac surgery are at increased risk of perioperative morbidity and mortality.
- Trial name
- NCT02642770
- Testing
- Transesophageal echocardiography
- Where
- India
- Volunteers
- 73 people
- Sponsor
- Post Graduate Institute of Medical Education and Research, Chandigarh
Heart; Surgery, Heart, Functional Disturbance as Result
The Effect of 10 Repetitions of Deep Breathing Exercises
The goal of this clinical trial is to learn and assess the effect of 10 repetitions of deep breathing exercises every 3 hours compared to 3 repetitions of deep breathing exercises on the sleep quality of patients after heart…
- Trial name
- NCT06435715
- Testing
- 10 Repetitions of Deep Breathing Exercise, 3 Repetitions of Deep Breathing Exercise
- Where
- Indonesia
- Volunteers
- 50 people
- Sponsor
- Universitas Indonesia
Surgical Wound Infection, Heart; Surgery, Heart, Functional Disturbance as Result
Early Detection of Surgical Wound Infections Using Sensor Technology
Infections that are caused by surgical incision are commonly known as surgical site infections (SSI). A surgical wound infection can develop at any time after surgery until the wound has healed (usually two to three weeks after…
- Trial name
- SSI-Sensor (NCT03401658)
- Testing
- Sensor light detector
- Where
- United Kingdom
- Sponsor
- Liverpool Heart and Chest Hospital NHS Foundation Trust
Heart; Surgery, Heart, Functional Disturbance as Result
Monitoring of Cardiac Function With 3-axis Accelerometers
Aim of the study: To validate accelerometers for continuous monitoring of global cardiac function during weaning from cardiopulmonary bypass (CPB) in cardiac surgery.
- Trial name
- NCT01926067
- Where
- Norway
- Volunteers
- 20 people
- Sponsor
- Oslo University Hospital
Surgical Wound, Wound Healing Delayed
Using AI Within Digital Wound Monitoring of Surgical Wounds to Prioritise Non-healing Wounds for Urgent Review
The goal of this clinical trial is to learn if artificial intelligence within digital wound monitoring of surgical wounds can prioritise non-healing wounds for urgent review in patients having first/redo CABG surgeries with or…
- Conditions
- Surgical Wound, Wound Healing Delayed, Heart; Surgery, Heart, Functional Disturbance as Result
- Trial name
- WISDOM (NCT06475703)
- Testing
- Isla wound prioritisation module, Standard follow-up
- Where
- 2 sites in United Kingdom
- Volunteers
- 120 people
- Sponsor
- Guy's and St Thomas' NHS Foundation Trust
Prosthesis Survival, Prosthesis; Cardiac, Heart, Functional Disturbance as Result
Transcatheter Aortic Valve Implantation Versus Standard Surgical Aortic Valve Replacement
The mechanical intervention is treating aortic valve stenosis (AVS) which may be performed using the standard open surgical approach for aortic valve replacement (AVR) or transcatheter aortic valve implantation (TAVI).
- Trial name
- TAVISAR (NCT05261204)
- Testing
- Transcatheter Aortic Valve Implantation, Bioprothesis, Sutureless
- Where
- France
- Volunteers
- 4,000 people
- Sponsor
- Centre Cardiologique du Nord
Heart; Surgery, Heart, Functional Disturbance as Result
The Role of Modified Ultrafiltration Following Open Heart Surgery
This study aims to investigate the effect of combining conventional ultrafiltration and modified ultrafiltration compared to conventional ultrafiltration alone in patients who underwent open heart surgery.
- Trial name
- NCT06085066
- Testing
- Conventional Ultrafiltration alone on Cardiopulmonary bypass, Conventional Ultrafiltration followed by Modified Ultrafitration on Cardiopulmonary bypass
- Where
- Indonesia
- Volunteers
- 38 people
- Sponsor
- Universitas Indonesia
Aortic Valve Disease, Prosthesis; Cardiac, Heart, Functional Disturbance as Result
Aortic Valve Replacement Above the Aortic Annulus (SA-AVR) With the Carpentier-Edwards Magna-Ease Bioprosthesis
Surgical valve replacement is commonly performed in patients with severe aortic valve disease. In small aortic annulus, implantation of bioprosthetic valves can be associated with limited functional capacity.
- Trial name
- SA-AVR (NCT03976817)
- Testing
- aortic valve replacement
- Where
- France
- Volunteers
- 117 people
- Sponsor
- Centre Chirurgical Marie Lannelongue
Quality of Life, Congenital Heart Disease
Exercise Training in Children With Corrective Cardiac Surgeries
To determine the effects of preoperative exercise therapy on postoperative cardiopulmonary outcomes and quality of life in children with corrective cardiac surgeries.Within literature there is limited evidence on preoperative…
- Conditions
- Quality of Life, Congenital Heart Disease, Heart; Surgery, Heart, Functional Disturbance as Result
- Trial name
- NCT05763238
- Testing
- INTERVENTION GROUP, CONTROL GROUP
- Where
- Pakistan
- Volunteers
- 46 people
- Sponsor
- Riphah International University
Heart; Surgery, Heart, Functional Disturbance as Result
The Use of Cooling Helmet for Neuroprotection Management in Open Heart Surgery
To know the relationship between the use of cooling helmet with the changes of NSE level and postoperative delirium event in open heart surgery
- Trial name
- NCT05264766
- Testing
- Cooling helmet on, Cooling helmet off
- Where
- Indonesia
- Volunteers
- 26 people
- Sponsor
- Universitas Indonesia
Heart; Surgery, Heart, Functional Disturbance as Result
Clinical Impact of Del Nido Cardioplegia in Adult Cardiac Surgery
Cardioplegia solutions have been used for myocardial protection in cardiac surgery for decades. Different cardioplegic strategies have been evaluated.
- Trial name
- NCT04094168
- Testing
- DEL NIDO CARDIOPLEGIA, COLD BLOOD BASED CARDIOPLEGIA
- Where
- Spain
- Volunteers
- 474 people
- Sponsor
- JESSICA GARCIA SUAREZ
Central Line-associated Bloodstream Infection (CLABSI), Central Venous Catheter Associated Bloodstream Infection
Central Venous Catheter Insertion Site and Colonization in Pediatric Cardiac Surgery
Randomized controlled trial comparing femoral vs internal jugular insertion site of central venous catheters (CVC) in newborns and infants undergoing cardiac surgery.
- Conditions
- Central Line-associated Bloodstream Infection (CLABSI), Central Venous Catheter Associated Bloodstream Infection, Heart; Surgery, Heart, Functional Disturbance as Result, Congenital Heart Disease
- Trial name
- PRECiSE (NCT03282292)
- Testing
- Internal jugular vein CVC insertion
- Where
- Italy
- Sponsor
- IRCCS Policlinico S. Donato
Heart; Surgery, Heart, Functional Disturbance as Result
Multifunctional Approach in Cardiac Surgery
Postoperative pain and swallowing disorders are complex, multifactorial phenomenon that frequently occur after cardiac surgery. Preoperative anxiety and the interaction between sex and other sociocultural factors may predict…
- Trial name
- TITANIC (NCT05824598)
- Testing
- Multifunctional rehabilitation treatment
- Where
- Italy
- Volunteers
- 44 people
- Sponsor
- Fondazione Don Carlo Gnocchi ETS