Clinical trials: Heart Arrest, Out-Of-Hospital
Cardiac Arrest
Prediction of Outcome in Out-of-Hospital Cardiac Arrest
In the course of prehospital respiratory and circulatory arrest, approximately 1000 persons are resuscitated by cardiopulmonary resuscitation in Upper Austria every year.
- Trial name
- PREDOHCA (NCT06030986)
- Testing
- ILCOR Utstein OHCA Core Outcome
- Where
- Austria
- Volunteers
- 10,000 people
- Sponsor
- Kepler University Hospital
Out-of-Hospital Cardiac Arrest, Pulmonary Ventilation
CAvent-Ventilation During Advanced Cardiopulmonary Resuscitation in Out-of-hospital Cardiac Arrest- an Observational Study
The aim of this observational study is to investigate how ventilations is given during cardiopulmonary resuscitation (CPR) given by advanced life support providers (ALS).
- Trial name
- CAvent (NCT04237727)
- Testing
- Fluxmed GrH portable pneumotachograph
- Where
- 5 sites in Netherlands, Sweden
- Volunteers
- 241 people
- Sponsor
- Uppsala University
Out-Of-Hospital Cardiac Arrest
Biochemical Makers for Outcome After Pediatric out-of Hospital Cardiac Arrest
This single-center study will validate serum, imaging and clinical markers to determine outcome of pediatric patients early after Out-of-Hospital cardiac arrest (OHCA).
- Trial name
- BIMOPECA (NCT03873662)
- Testing
- Blood sample
- Where
- Czechia
- Volunteers
- 4 people
- Sponsor
- Brno University Hospital
Out-of-hospital Cardiac Arrest
Application of Mechanical Cardiopulmonary Resuscitation Devices and Their Value in Out-of-hospital Cardiac Arrest: A Retrospective Analysis of the German Resuscitation Registry
The aim of this study was to analyse a large CPR database, the German Resuscitation Registry, to evaluate potential benefits of mechanical CPR devices over manual CPR in adult cardiac arrest victims.
- Trial name
- NCT02932124
- Testing
- mechanical chest compression device
- Volunteers
- 19,609 people
- Sponsor
- German Resuscitation Registry
Out-Of-Hospital Cardiac Arrest, Post Cardiac Arrest Syndrome
Pre-hospital Post ROSC Care: Are we Achieving Our Targets?
Rational: Out of hospital cardiac arrest is a devastating event with a high mortality. Survival rates have increased over the last years, with the availability of AED's and public BLS.
- Conditions
- Out-Of-Hospital Cardiac Arrest, Post Cardiac Arrest Syndrome, Emergency Medical Services
- Trial name
- POP-ROC (NCT04339257)
- Volunteers
- 175 people
- Sponsor
- University Medical Center Groningen
Heart Arrest, Cardiac Arrest, Out-Of-Hospital
Synergy of Elevation of the Head and Thorax and REBOA During Out-of-Hospital Cardiac Arrest
Long-term neurological outcome after successful resuscitation of cardiac arrest remains poor, mainly due to cerebral hypoperfusion and severe hypoxic-ischemic brain injuries.
- Conditions
- Heart Arrest, Cardiac Arrest, Out-Of-Hospital, Cardiopulmonary Arrest, Cardiopulmonary Resuscitation
- Trial name
- GRAVITY2 (NCT06537492)
- Testing
- REBOA, Head-Up Cardiopulmonary Resuscitation (AHUP-CPR), Mechanical Chest Compression Device with Active Chest Decompression
- Where
- France
- Volunteers
- 35 people
- Sponsor
- University Hospital, Grenoble
Intubation Complication, Cardiopulmonary Arrest
IntuBrite Versus Macintosh for Endotracheal Intubation in Out of Hospital Cardiac Arrest
a randomized, parallel, non-blinded trial in a single Emergency Mdeical Service in Poland within a group of 34 ground ambulances crews, comparing time and first pass success (FPS) for endotracheal intubation (ETI) in DL using the…
- Trial name
- NCT05607836
- Testing
- IntuBrite intubation, Macintosh laryngoscope
- Where
- Poland
- Volunteers
- 86 people
- Sponsor
- Medical University of Lodz
Healthy Participants, Knowledge Acquisition
Learning Cardiopulmonary Resuscitation in the School Setting: RCP-KNOW Project.
Title: Out-of-hospital cardiorespiratory arrest and learning cardiopulmonary resuscitation in the school setting: evidence synthesis. CPR-KNOW PROYECT.
- Conditions
- Healthy Participants, Knowledge Acquisition, Cardiopulmonary Resuscitation (CPR), Children
- Trial name
- RCP-KNOW (NCT07292532)
- Testing
- Cardiopulmonary Resuscitation Teaching Intervention in Children
- Where
- 2 sites in Spain
- Volunteers
- 550 people, healthy volunteers welcome
- Sponsor
- University of Castilla-La Mancha
Out-Of-Hospital Cardiac Arrest
Selective Cerebral Hypothermia Trial - Under Extracorporeal Cardiopulmonary Resuscitation (SHOT-ECPR)
The study is designed as a pilot, open-label study to investigate the feasibility and safety of selective cerebral hypothermia in OHCA patients receiving ECPR.
- Trial name
- NCT03345706
- Testing
- Selective cerebral hypothermia, Regular hypothermia
- Where
- Taiwan
- Volunteers
- 20 people
- Sponsor
- National Taiwan University Hospital
Out-of-Hospital Cardiac Arrest, Extracorporeal Cardiopulmonary Resuscitation
Refractory Cardiac Arrest Treated On Field By ECMO
Out-of-hospital cardiac arrest without resumption of spontaneous circulatory activity despite advanced medical resuscitation is considered refractory.
- Trial name
- ReCATOBE (NCT06397417)
- Testing
- Data collection
- Where
- France
- Volunteers
- 840 people
- Sponsor
- Assistance Publique - Hôpitaux de Paris
Cardiopulmonary Arrest Outcome
Optimizing Resuscitation After Cardiac Arrest in the Community
Resuscitative efforts have been shown to be unsuccessful in most cases of out-of-hospital cardiac arrest (OHCA), and survivors who do recover cardiac function often sustain severe hypoxic brain damage.
- Trial name
- NCT00998140
- Where
- Israel
- Volunteers
- 1,600 people
- Sponsor
- Shaare Zedek Medical Center
Out-of-Hospital Cardiac Arrest
AMCPR (Augmented-Medication CardioPulmonary Resuscitation) Trial for OHCA
The investigators aimed to evaluate the effect of AMCPR (Augmented-Medication CardioPulmonary Resuscitation: administration of additional vasopressin to titrate to arterial diastolic blood pressure over 20 mmHg) on…
- Trial name
- NCT03191240
- Testing
- Vasopressins, Normal saline
- Where
- 2 sites in South Korea
- Volunteers
- 110 people
- Sponsor
- Asan Medical Center
Cardiac Arrest, Cardiopulmonary Resuscitation
Comparison of Manual Cardiopulmonary Resuscitation (CPR) Versus Automatic CPR Machine During Ambulance Transport.
This is a randomized controlled prospective study which assigned patient to receive manual CPR or automatic CPR machine use. The quality and efficacy between manual CPR and machine CPR will be evaluated.
- Trial name
- NCT00308815
- Testing
- Automatic CPR machine
- Where
- Taiwan
- Volunteers
- 100 people
- Sponsor
- National Taiwan University Hospital
Cardiac Arrest
RACE-CARS - RAndomized Cluster Evaluation of Cardiac ARrest Systems
RACE-CARS is a real-world cluster-randomized trial designed to evaluate a multifaceted community and health systems intervention aimed to improve outcomes of out-of-hospital cardiac arrest.
- Trial name
- NCT04660526
- Testing
- Rapid cardiac arrest recognition that triggers immediate priority EMS/first responder dispatch by 911 operators, Systematic bystander resuscitation instruction by 911 operators, Comprehensive community training of lay people in CPR and AED use.
- Where
- United States
- Volunteers
- 20,000 people
- Sponsor
- Duke University
Out-of-Hospital Cardiac Arrest (Simulated)
Simulation and Feasibility Study of Drone-Delivered AED for Out-of-Hospital Cardiac Arrest
Background: Survival after out-of-hospital cardiac arrest (OHCA) depends heavily on early defibrillation. Reducing the time from cardiac arrest to defibrillation is a key factor in improving survival.
- Trial name
- NCT07508774
- Testing
- Drone-Based AED Delivery System, Standard Ground Ambulance Response Pathway Simulation
- Where
- China
- Volunteers
- 24 people, healthy volunteers welcome
- Sponsor
- Ye Sheng
Out-of-Hospital Cardiac Arrest
Survival Study After Out-of-hospital Cardiac Arrest
The purpose of this study is to determine if dual dispatch of ambulance, fire fighters and/or police in out-of-hospital cardiac arrest (OHCA), can reduce the time to cardiopulmonary resuscitation (CPR) and defibrillation, thus…
- Trial name
- SAMS (NCT02184468)
- Testing
- Simultaneously dispatch of firefighters and/or police in case of OHCA
- Where
- Sweden
- Volunteers
- 6,000 people
- Sponsor
- Karolinska Institutet
Out-of-Hospital Cardiac Arrest
Combining Performance of Call EMS and Simultaneous Chest Compressions in a Lone Rescuer CPR
Investigators designed the novel combining technique that rescuer start the chest compression with one hand during calling for help to the Emergency Medical System (EMS) via a cell phone with another hand when he witnessed the…
- Trial name
- NCT02646046
- Testing
- Combi lone-CPR, Conventional lone-CPR
- Where
- South Korea
- Volunteers
- 110 people, healthy volunteers welcome
- Sponsor
- Konkuk University Medical Center
Out-Of-Hospital Cardiac Arrest
Cardiac Arrest in Residential Areas With Mobile First-responder Activation
The study aims to increase proportions of bystander defibrillation during out-of-hospital cardiac arrest (hereof referred to as cardiac arrest) in residential areas with a high density of cardiac arrests.
- Trial name
- CARAMBA (NCT04446585)
- Testing
- Automated External Defibrillator (AED), Training in cardiopulmonary resuscitation and AED use, Activation of citizen responders
- Where
- Denmark
- Volunteers
- 260 people
- Sponsor
- Emergency Medical Services, Capital Region, Denmark
Cardiac Arrest
Non-invasive Neurological Evaluation During CPR
Cardiac arrest remains a leading cause of death, currently affecting >250,000 Europeans outside the hospital each year. Manual cardiopulmonary resuscitation (CPR) provides between 15 to 30 % of normal blood flow to the heart and…
- Trial name
- Neuro-E-CPR (NCT02684955)
- Testing
- Cerebral spectroscopy, Pupillometry
- Where
- 2 sites in France
- Volunteers
- 112 people
- Sponsor
- University Hospital, Grenoble
BLS, Out-Of-Hospital Cardiac Arrest
Geographical Association Between Basic Life Support Courses, Bystander Cardiopulmonary Resuscitation and Survival
Background Since 2001 when the Danish Cardiac Arrest Registry was first established several large-scale interventions aimed at the entire Danish population from all ages have been initiated.
- Trial name
- Geodata-BLS (NCT04353089)
- Testing
- Basic life support courses
- Where
- Denmark
- Volunteers
- 900,000 people, healthy volunteers welcome
- Sponsor
- Emergency Medical Services, Capital Region, Denmark