Clinical trials: Heart Arrest, Out-Of-Hospital
Coping Skills
CPR Training in Students to Increase Bystander Intervention in Out-of-hospital Cardiac Arrest.
The overall aim of this thesis is to identify the factors that may affect 13 year old students' acquisition of CPR skills and their willingness to act.
- Trial name
- NCT03233490
- Testing
- web course, CPR training
- Volunteers
- 1,547 people, healthy volunteers welcome
- Sponsor
- Karolinska Institutet
Out-Of-Hospital Cardiac Arrest, Oxygen Toxicity
ORI to Reduce Hyperoxia After Out Hospital Cardiac Arrest
The investigator's research proposal is a randomized controlled study evaluating two different monitoring strategies to titrate FiO2 in order to rapidly and safely achieve optimal SatO2 targets during early ROSC of non-traumatic…
- Trial name
- ORI-ONE (NCT03653325)
- Testing
- ORI measurement, oxygen saturation measurement
- Where
- 2 sites in Belgium
- Volunteers
- 100 people
- Sponsor
- Centre Hospitalier Universitaire Saint Pierre
Wounds and Injuries, Out-of-Hospital Cardiac Arrest
Psychoactive Drug Use and Acute Care Use After Trauma and Out-of-Hospital Cardiac Arrest
This retrospective population-based cohort study uses linked administrative healthcare data from the Local Health Authority of Bologna (Italy) to describe the use of four classes of psychoactive drugs (opioids, antiepileptics…
- Conditions
- Wounds and Injuries, Out-of-Hospital Cardiac Arrest, Traumatic Brain Injury
- Trial name
- LIFT-C (NCT07882589)
- Testing
- Opioids (ATC N02A), Antiepileptics (ATC N03A), Antipsychotics (ATC N05A)
- Where
- 2 sites in Italy
- Volunteers
- 52,720 people
- Sponsor
- Azienda Usl di Bologna
Cardiac Arrest, Metabolic Acidosis
Bicarbonate in Patients With Out-of-hospital Cardiac Arrest
A pilot study to evaluate the effect of sodium bicarbonate administration on cardiopulmonary resuscitation results and outcomes in cardiac arrest patient with severe metabolic acidosis.
- Trial name
- NCT02303548
- Testing
- Sodium bicarbonate, Normal saline
- Volunteers
- 50 people
- Sponsor
- Asan Medical Center
Out of Hospital Cardiac Arrest
Ambulance Clinicians' Experiences of Attending OHCA in Children
This research will explore ambulance clinicians' experiences of attending out of hospital cardiac arrest (OHCA) incidents involving children. OHCA occurs when the heart stops beating.
- Trial name
- NCT06922019
- Where
- United Kingdom
- Volunteers
- 2,137 people, healthy volunteers welcome
- Sponsor
- University of Warwick
Cardiac Arrest
Doppler Sonography of Cerebral Blood Flow for Early Prognostication After Out-of-hospital Cardiac Arrest
Objective: To assess neurologic prognostication by early Transcranial Doppler Sonography (TCD) in comatose survivors after cardiac arrest.
- Trial name
- DOTAC (NCT03270683)
- Where
- France
- Volunteers
- 52 people
- Sponsor
- Rennes University Hospital
Out-of-hospital Cardiac Arrest
Prophylactic Antibiotics in Comatose Survivors of Out-of-hospital Cardiac Arrest
The purpose of this study is to determine whether there is potential benefits of prophylactic antibiotic treatment in comatose survivors of out-of-hospital cardiac arrest (OHCA) treated in intensive care unit with therapeutic…
- Trial name
- NCT02899507
- Testing
- Amoxicillin-Clavulanic acid
- Where
- Slovenia
- Volunteers
- 60 people
- Sponsor
- University Medical Centre Ljubljana
Cardiac Arrest, Sudden Cardiac Death
Epidemiological Study of Out-of-hospital Cardiac Arrest in Guangzhou
Aim This was a population-based retrospective cohort study of OHCA. This study intends to retrospectively analyze the data of pre-hospital emergency system in Guangzhou for 10 years, explore the incidence trend of OHCA in…
- Trial name
- NCT06448156
- Testing
- "cardiac arrest" and "sudden death"
- Where
- China
- Volunteers
- 44,375 people
- Sponsor
- Sun Yat-Sen Memorial Hospital of Sun Yat-Sen University
Cardiac Arrest (CA), Out-of-hospital Cardiac Arrest (OHCA)
Abdominal Aortic Tourniquet Application for Non-Traumatic Out-of-Hospital Cardiac Arrest
The aim of the study is to investigate whether occluding the abdominal aorta with an external device could be a potential therapeutic option in cases of non-traumatic cardiac arrest occurring outside of a hospital.
- Conditions
- Cardiac Arrest (CA), Out-of-hospital Cardiac Arrest (OHCA), Asystole, Pulseless Electrical Activity
- Trial name
- ATTICA (NCT07573566)
- Testing
- Abdominal Aortic Junction Tourniquet in non-traumatic out-of-hospital cardiac arrest
- Where
- Austria
- Volunteers
- 5 people
- Sponsor
- Klinikum Klagenfurt am Wörthersee
Out-of-Hospital Cardiac Arrest
Direct or Subacute Coronary Angiography in Out-of-hospital Cardiac Arrest
The overall aim of this prospective, randomized study is to investigate whether acute coronary angiography (within 120 minutes) with a predefined strategy for revascularization, will improve 30-day survival in patients with out…
- Trial name
- DISCO (NCT02309151)
- Testing
- Immediate coronary angiography
- Where
- 21 sites in Denmark, Netherlands and 1 more
- Volunteers
- 1,003 people
- Sponsor
- Uppsala University
Out-Of-Hospital Cardiac Arrest, Trauma
AI to Improve Data From Danish Cardiac Arrest Registry
Out-of-hospital cardiac arrest is a leading cause of death worldwide and patient outcome vary substantially throughout regions suggesting further evaluation and potential for improvement.When focussing on subgroups of OHCA, data…
- Conditions
- Out-Of-Hospital Cardiac Arrest, Trauma, Drug Overdose, Electrocution
- Trial name
- NCT05308303
- Where
- Denmark
- Volunteers
- 31,200 people
- Sponsor
- Prehospital Center, Region Zealand
Cardiac Arrest
Online Formation in Cardiopulmonary Resuscitation in a Rural Area.
Background: Sudden death due to cardiorespiratory arrest has a high mortality and in most cases occurs in out-of-hospital. Cardiopulmonary resuscitation (CPR) initiated immediately by witnesses doubles survival.
- Trial name
- RECADE (NCT05747495)
- Testing
- Online training in CPR-AED
- Where
- Spain
- Volunteers
- 52 people, healthy volunteers welcome
- Sponsor
- Fundacio d'Investigacio en Atencio Primaria Jordi Gol i Gurina
Out-of-hospital Cardiac Arrest (OHCA)
Impact of Low Dose Epinephrine in the Management of Out-of-hospital Cardiac Arrest on Neurological Outcome
This study will test whether a lower dose of epinephrine (0.5 mg) given during emergency treatment for out-of-hospital cardiac arrest helps more patients survive with good brain function, compared to the standard dose (1 mg).
- Trial name
- Low-EPI (NCT07442071)
- Testing
- Epinephrine 0.5 mg intravenous bolus, Epinephrine 1 mg intravenous bolus
- Where
- 26 sites in France
- Volunteers
- 4,336 people
- Sponsor
- Central Hospital, Nancy, France
Cardiac Arrest, Out-Of-Hospital
Late Biomarkers in Adult Survivors After Out-of-hospital Cardiac Arrest
Blood samples are collected at six months follow-up from adult survivors after out-of-hospital cardiac arrest. Patients will be informed about the study and if they consent to participation, venous blood will be drawn by…
- Trial name
- NCT06587763
- Where
- 3 sites in Sweden
- Sponsor
- Region Skane
Out of Hospital Cardiac Arrest, Cardiac Arrest
"The Effect of the Use of an Autotransfusion Device on Hemodynamic Parameters During Resuscitation".
The purpose of the research (pilot study) is to determine the impact of the use of the autotransfusion device on hemodynamic parameters during resuscitation.
- Trial name
- NCT06153160
- Testing
- HemaShock device
- Where
- 2 sites in Slovenia
- Volunteers
- 24 people, healthy volunteers welcome
- Sponsor
- University Medical Centre Maribor
Infection, Bacterial, Out-Of-Hospital Cardiac Arrest
Impact of Early Antibiotics on Non-Traumatic Out of Hospital Cardiac Arrest (OHCA)
Specific Aim : The specific aim is to conduct a randomized prospective clinical trial to determine whether no antibiotics in OHCA patients in the ED with very low likelihood of infection is non-inferior to early antibiotic…
- Trial name
- NCT05914779
- Testing
- No use of antibiotics, with antibiotics treatment
- Where
- Qatar
- Volunteers
- 1,000 people
- Sponsor
- Hamad Medical Corporation
Drowning, Out-Of-Hospital Cardiac Arrest
Drowning-related OHCA in Denmark: A Six-year Registry-based Study
Within a six-year period from 2016-2021, this retrospective cohort study aims to: 1) report the national incidence of drowning related OHCA's among cases attended by the Danish Emergency Medical Services (EMS), 2) assess survival…
- Trial name
- NCT05323097
- Testing
- Drowning-related OHCA
- Where
- Denmark
- Volunteers
- 31,200 people
- Sponsor
- Prehospital Center, Region Zealand
Cardiac Arrest
Pre-shock Cardiopulmonary Resuscitation to Patients With Out-of-hospital Resuscitation, A Randomised Clinical Trial
1. Pre-shock cardiopulmonary resuscitation might benefit the survival of out-of-hospital cardiac patients with ventricular fibrillation / ventricular tachycardia in a post-hoc analysis of a prehospital trial conducted in Europe…
- Trial name
- CPR (NCT00650962)
- Testing
- cardiopulmonary resuscitation, Rhythm analysis
- Where
- Taiwan
- Volunteers
- 1,666 people
- Sponsor
- National Taiwan University Hospital
Out-of-Hospital Cardiac Arrest
Implementation of Gold Standard EMS CPR Programs for 2% Improvement in Survival Rates of Out-of-Hospital Cardiac Arrest in a Metropolitan City
This study aims to improve the survival rate of out-of-hospital cardiac arrest patients by 2% through a bundle of three intervention measures including: 1) dispatcher-assisted CPR, 2) multi-tiered response team CPR, and 3)…
- Trial name
- 2% Project (NCT02540629)
- Testing
- Bundled EMS CPR approach including dispatcher-assisted CPR, 3-person team CPR, and feedback CPR monitoring device
- Where
- South Korea
- Volunteers
- 12,670 people
- Sponsor
- Seoul National University Hospital
Out-Of-Hospital Cardiac Arrest
P25/30 SSEPs and Neurological Prognosis After Cardiac Arrest
Study Title: Early recorded P25/30 somatosensory evoked potentials are associated with neurologic prognosis of comatose survivors after out of hospital cardiac arrest.
- Trial name
- NCT03881865
- Where
- United Kingdom
- Volunteers
- 93 people
- Sponsor
- University Hospital Plymouth NHS Trust