Clinical trials: Heart Diseases, Coronary
Heart Failure With Reduced Ejection Fraction (HFrEF)
Effectiveness of Video Monitoring and Care Transition for Heart Failure Patients (EVIT-HF): Randomized Clinical Trial
The goal of this clinical trial is to measure the effectiveness of video monitoring associated with the transition of care for patients with heart failure.
- Trial name
- EVIT-HF (NCT06731166)
- Testing
- self-care
- Where
- Brazil
- Volunteers
- 140 people
- Sponsor
- Federal University of Uberlandia
Neurological Complications, Mitral Valve Insufficiency
Magnetic Resonance Imaging for Cerebral Embolization During Minimal Invasive Mitral Valve Surgery
The purpose of this study is to prospectively evaluate major and minor neurologic events in patients undergoing right mini-thoracotomy mitral valve surgery and to compare different aortic clamping techniques; specifically, the…
- Trial name
- NCT02818166
- Testing
- Mitral valve surgery
- Where
- Italy
- Volunteers
- 80 people
- Sponsor
- University of Turin, Italy
Acute Myocardial Infarction
Safety Study of AMI MultiStem® to Treat Heart Attacks
The purpose of this study is to determine if escalating doses of AMI MultiStem® delivered by catheter can safely be given to patients that have had a recent heart attack treated with stent implantation.
- Trial name
- NCT00677222
- Testing
- AMI MultiStem®
- Where
- 7 sites in United States
- Volunteers
- 25 people
- Sponsor
- Healios K.K.
Hypertrophic Cardiomyopathy (HCM)
Perfusion Abnormalities in Hypertrophic Cardiomyopathy
The purpose of this study is to investigate whether myocardial microvascular perfusion in patients with hypertrophic cardiomyopathy improved after initiation of cardiac myosin inhibitor therapy.
- Trial name
- NCT06599229
- Testing
- myocardial contrast echo
- Where
- United States
- Volunteers
- 30 people
- Sponsor
- University of Virginia
Type 2 Diabetes Mellitus, Coronary Artery Disease
DARE: Diabetes in cArdiac REhabilitation
The aim of the DARE study is to see whether strict glycemic control during cardiac rehabilitation may ameliorate the improvement of exercise capacities (VO2 peak, peak workload, ventilatory threshold)in patients with type 2…
- Trial name
- NCT00354237
- Testing
- Conventional antidiabetic treatment, Intensive insulin treatment
- Where
- 12 sites in France
- Volunteers
- 60 people
- Sponsor
- Centre Hospitalier Universitaire Dijon
Paroxysmal Atrial Fibrillation
Electrical Coupling Information From The Rhythmia HDx System And DirectSense Technology In Subjects With Paroxysmal Atrial Fibrillation
The objective of the study is to collect data on the use of the Rhythmia HDx mapping system running commercially available Software Version 2.0 or any future commercially available Software Version with DirectSense technology and…
- Trial name
- LOCALIZE (NCT03232645)
- Testing
- Ablation procedure
- Where
- 6 sites in France, Germany and 2 more
- Volunteers
- 62 people
- Sponsor
- Boston Scientific Corporation
Calcific Aortic Valve Disease, Aortic Valve Stenosis
Serum and Cellular Biomarkers for Aortic Valve Stenosis
AthenaValve aims to develop and initial validate a novel serum diagnostic kit, for the assessment of severity and prognosis of progression of aortic valve stenosis (AS, a devastating disease without early diagnosis and medical…
- Conditions
- Calcific Aortic Valve Disease, Aortic Valve Stenosis, Aortic Valve, Calcification of
- Trial name
- AthenaValve (NCT04312139)
- Testing
- Echocardiography, Computerized Tomography Aortic Valve Calcium Score, Untargeted LC/MS and LC-MS/MS
- Where
- 2 sites in Greece
- Volunteers
- 280 people
- Sponsor
- National and Kapodistrian University of Athens
Tinnitus
FR-taVNS Tinnitus Tria
Tinnitus is a common neurosensory symptom affecting 12-30% of adults and is closely associated with anxiety, sleep disturbance, and autonomic dysregulation.
- Trial name
- NCT07711639
- Testing
- True Foot Reflexology, True ta-VNS, True Auricular Acupressure
- Where
- Taiwan
- Volunteers
- 180 people
- Sponsor
- Tzu Chi University
Diabetes Mellitus, Congestive Heart Failure
Homing in on Health: Study of a Home Delivered Chronic Disease Self Management Program
The purpose of the study is to determine the effectiveness of a home-delivered variant of the chronic disease self management program in improving health outcomes in patients with chronic conditions.
- Conditions
- Diabetes Mellitus, Congestive Heart Failure, Arthritis, COPD
- Trial name
- NCT00263939
- Testing
- Homing in on Health
- Where
- United States
- Volunteers
- 415 people
- Sponsor
- Agency for Healthcare Research and Quality (AHRQ)
Coronary Artery Disease
Precise Procedural and PCI Plan (P4)
Computed tomography (CT) has become an established tool in the diagnostic workup of patients with suspected coronary artery disease (CAD).
- Trial name
- P4 (NCT05253677)
- Testing
- CT-guided PCI, IVUS-guided PCI
- Where
- 23 sites in United States, Belgium and 6 more
- Volunteers
- 1,090 people
- Sponsor
- CoreAalst BV
Heart Failure
Evaluation of Left Ventricular AutoThreshold
This study will collect data on a new feature for future heart failure devices via an external non-implantable system.
- Trial name
- ELEVATE (NCT00812201)
- Testing
- No intervention is used. Collection of signals only.
- Where
- 2 sites in United States
- Volunteers
- 80 people
- Sponsor
- Boston Scientific Corporation
Chronic Heart Failure
The TOSCA Registry: Hormonal and Metabolic Deficiencies in Chronic Heart Failure
The objective of this study is to determine whether the presence of metabolic alteration and anabolic deficiencies in patients with chronic heart failure are able to identify a subset of patients with poor outcome.
- Trial name
- TOSCA (NCT02335801)
- Where
- 17 sites in Italy
- Volunteers
- 650 people
- Sponsor
- Federico II University
Aortic Stenosis, Amyloid
Atrial Amyloid May Influence Outcomes in Patients Undergoing Surgical Aortic Valve Replacement
Background (Context): Some older adults who undergo surgery to replace a narrowed heart valve (called aortic stenosis) may also have small protein deposits in their heart.
- Trial name
- AORTICMARKER (NCT07105501)
- Where
- Spain
- Volunteers
- 110 people
- Sponsor
- Germans Trias i Pujol Hospital
Coronary Artery Disease
Cangrelor Prasugrel Transition Study
To demonstrate that patients treated with cangrelor can be directly switched to oral prasugrel and that patients treated with prasugrel can be switched to cangrelor without a significant decrease in the extent of inhibition of…
- Trial name
- NCT01852019
- Testing
- Cangrelor, Prasugrel
- Where
- United States
- Volunteers
- 12 people
- Sponsor
- The Medicines Company
Congenital Heart Disease
Proposal for Parental Guidance and Early Stimulation in Children With Congenital Heart Disease: Randomized Trial
Problem: With the increased survival rate of children with congenital heart disease, other health problems, in addition to the clinic, have emerged, such as the risks of developmental delay to which these children are exposed.
- Trial name
- NCT04152330
- Testing
- Early stimulation protocol on neuropsychomotor development of children with congenital heart disease
- Where
- Brazil
- Volunteers
- 44 people
- Sponsor
- Instituto de Cardiologia do Rio Grande do Sul
Diastolic Heart Failure
Perhexiline Therapy in Heart Failure With Preserved Ejection Fraction Syndrome
Up to half of all patients with clinical features of heart failure are found to have normal heart pumping function. Recently the investigators have shown that a drug called perhexiline markedly improved exercise capacity and…
- Trial name
- NCT00839228
- Testing
- Perhexiline
- Where
- United Kingdom
- Volunteers
- 70 people
- Sponsor
- University of Aberdeen
Ventricular Premature Complexes
Relativity Study Between Idiopathic Ventricular Arrhythmia and Sex Hormone Levels in Different Stages of Menstrual Cycle
The purpose of this study is to determine whether the occurrence of idiopathic right ventricular outflow tract(RVOT) arrhythmia is relative to sex hormone levels in different stages of female menstrual cycle
- Trial name
- NCT00606736
- Where
- China
- Volunteers
- healthy volunteers welcome
- Sponsor
- Harbin Medical University
Atrial Fibrillation
a Novel Individualized Substrate Modification Approach for the Treatment of Long-standing Persistent Atrial Fibrillation
The purpose of this study is to compare effectiveness of two substrate modification approaches in long-standing persistent atrial fibrillation patients, and hypothesized that a substrate-based, individualized substrate…
- Trial name
- NCT02477592
- Testing
- individualized substrate modification, stepwise ablation
- Where
- China
- Volunteers
- 220 people
- Sponsor
- RenJi Hospital
Heart Failure
Comparison Between Internal and External Chest Impedance Measurement
To compare two methods of chest impedance: the Medtronics Optivol Measurement via CRT pacemakers for patients with heart failure and external non-invasive measurement
- Trial name
- NCT01296282
- Testing
- Medronics CRT Optivol Impedance Measurement, External Thoracic Impedance Measurement
- Where
- Israel
- Volunteers
- 50 people
- Sponsor
- Hillel Yaffe Medical Center
Coronary Artery Disease
The Impact of the Routine Aminophylline Administration Following Regadenoson Stress on SPECT Myocardial Perfusion
The investigators developed a modified regadenoson nuclear stress test of the heart that incorporates an aminophylline injection following regadenoson (The ASSUAGE protocol).
- Trial name
- ASSUAGE-MPI (NCT01655524)
- Testing
- ASSUAGE Protocol
- Where
- United States
- Sponsor
- Rush University Medical Center
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