Clinical trials: Heart Failure, Unspecified
Anterior Myocardial Infarction, Heart Failure
RIGENERA 2.0 Trial
Study Objectives: To determine whether, in patients with large acute myocardial infarction undergoing primary or rescue angioplasty, the administration of subcutaneous Lenograstim [recombinant human Granulocyte-Colony Stimulating…
- Trial name
- RIGENERA (NCT02502747)
- Testing
- rhu G-CSF, optimal standard of care, Myocardial Contrast Echocardiography
- Where
- Italy
- Sponsor
- Catholic University of the Sacred Heart
Urocortin 2
Comparison Between Urocortin 2 and Brain Type Natriuretic Peptide
1. Evaluation of the role of serum urocortin 2 levels in acute decompensated HF patients and their association with clinical and echocardiographic findings. 2.
- Trial name
- NCT05115552
- Volunteers
- 60 people
- Sponsor
- Assiut University
Heart Failure
Ultrasound by Nurses in Heart Failure Patients
Cross-over study aimed to study the diagnostic and clinical impact of routinely adding a pocket-size ultrasound examination to traditional care at a outpatient heart failure clinic.
- Trial name
- NCT01794715
- Testing
- Ultrasound examination by nurses
- Where
- Norway
- Volunteers
- 62 people
- Sponsor
- Helse Nord-Trøndelag HF
Bradycardia, Heart Failure
BIO|CONCEPT.Amvia Study
The goal of this exploratory study is to test the preliminary safety and product performance of the new Amvia/Solvia pacemaker family in subjects that require a pacemaker or cardiac resynchronization therapy pacemaker (CRT-P)…
- Trial name
- NCT05610176
- Testing
- Amvia Sky pacemaker or CRT-P device
- Where
- 7 sites in Australia, New Zealand
- Volunteers
- 52 people
- Sponsor
- Biotronik Australia Pty Ltd.
Myocardial Infarct, Heart Failure
IMPACT-CABG Trial: IMPlantation of Autologous CD133+ sTem Cells in Patients Undergoing CABG
Following myocardial infarct, cellular therapy is a potential approach to repopulate the injured myocardium, to treat heart failure and restore cardiac function.
- Trial name
- IMPACT-CABG (NCT01033617)
- Testing
- Injection of stem cells at time of coronary artery bypass grafting
- Where
- Canada
- Volunteers
- 20 people
- Sponsor
- Centre hospitalier de l'Université de Montréal (CHUM)
Decompensated Heart Failure
BNP Guided Care in Addition to Multidisciplinary Care
HF is associated with repeated hospitalisations and poor prognosis.The aim of this study is to investigate whether BNP-guided care (BGC) in addition to multidisciplinary management(MM) improves outcome compared to HNC alone or…
- Trial name
- NCT00355017
- Testing
- BNP-guided care in addition to multidisciplinary management
- Sponsor
- Medical University of Vienna
Diabetes Mellitus, Heart Failure
Results of Tc99m-Maraciclatide Scintigraphy in Subjects With Diabetes Mellitus and Heart Failure With Preserved Left Ventricular Ejection Fraction
The purpose of this study is to evaluate the results of 99mTc maraciclatide scintigraphy in diabetic subjects with HFPEF. A maximum of 20 subjects with Diabetes Mellitus (DM) and Heart Failure With Preserved Left Ventricular…
- Trial name
- NCT01440517
- Testing
- Tc99m-Maraciclatide
- Where
- United States
- Volunteers
- 4 people
- Sponsor
- GE Healthcare
Heart Failure and Impaired Kidney Function
Study to Evaluate the Effect of Balcinrenone/Dapagliflozin in Patients With Heart Failure and Impaired Kidney Function
This is a Phase III, international, multi-centre, randomised, double-blind, parallel-group, double-dummy, active-controlled, event-driven study in patients with chronic HF and impaired kidney function who had a recent HF event.
- Trial name
- BalanceD-HF (NCT06307652)
- Where
- 852 sites in United States, Argentina and 37 more
- Volunteers
- 3,850 people
- Sponsor
- AstraZeneca
Acute on Chronic Heart Failure
Model for Heart Failure ExAcerbation Reduction Trial
Heart failure is the leading cause of hospitalizations and readmissions in the United States and is a tremendous economic strain on our healthcare system.
- Trial name
- HEART (NCT01726985)
- Testing
- Parameter Based Clinical Disposition
- Where
- United States
- Volunteers
- 230 people
- Sponsor
- Cleveland Clinic Florida
Cardiogenic Shock, Acute Heart Failure (AHF)
Multimodal Phenotyping In Patients Referred With Acute Cardiac faiLurE
The goal of this observational study is to learn whether information collected during routine hospital care, together with blood and urine samples, can help doctors better identify different types of cardiogenic shock and better…
- Trial name
- MIRACLE (NCT07515508)
- Where
- 4 sites in Germany
- Volunteers
- 600 people
- Sponsor
- University Heart Center Freiburg - Bad Krozingen
Heart Failure NYHA Class I, Heart Failure NYHA Class II
Future Patient - Telerehabilitation of Heart Failure Patients
The idea behind the Future Patient research project is to develop a telerehabilitation program and tools for patients with heart failure.
- Conditions
- Heart Failure NYHA Class I, Heart Failure NYHA Class II, Heart Failure NYHA Class III, Heart Failure NYHA Class IV
- Trial name
- NCT03388918
- Testing
- Telerehabilitation
- Where
- Denmark
- Volunteers
- 140 people
- Sponsor
- Aalborg University
End-stage Heart Failure
Cardiac Mitochondrial Function in Explanted Human Hearts
Background: Treatment of heart failure has improved considerably in the past decades. Despite this improvement, the disease may progress into an end-stage ultimately leaving the physicians with no other treatment option than…
- Trial name
- NCT04500938
- Volunteers
- 24 people
- Sponsor
- University of Aarhus
Heart Failure, Cardiovascular Diseases
Anti-thrombotic Monotherapy in HeartMate 3 Left Ventricular Assist System (LVAS)
The purpose of this prospective controlled study is to obtain a multi-center safety and feasibility data on patients managed with anti-thrombotic monotherapy with HeartMate 3 LVAS.
- Trial name
- NCT03781258
- Testing
- Warfarin
- Where
- Czechia
- Volunteers
- 20 people
- Sponsor
- Institute for Clinical and Experimental Medicine
Heart Failure, Comorbidity
Role of Comorbidities in Chronic Heart Failure Study
This study aims to create a database of patients with stable and chronic heart failure with comprehensive assessment of bone, skeletal and vascular status.
- Conditions
- Heart Failure, Comorbidity, Osteoporosis, Pulse Wave Analysis
- Trial name
- RoC-HF (NCT02922478)
- Testing
- X-ray of the spine, Ambulatory blood pressure monitoring (ABPM), Dual X-ray absorptiometry
- Where
- Austria
- Volunteers
- 205 people
- Sponsor
- Medical University of Graz
Heart Failure, Depressive Symptoms
Effects of a Rehabilitation Program on Immune Activation and Mood in Heart Failure Patients
The aim of this descriptive study is to examine potential changes regarding inflammatory cytokine levels, depressive symptoms and quality of life over the course of the 4-week inpatient rehabilitation program which includes a…
- Trial name
- NCT02358525
- Testing
- multi-modality rehabilitation program for heart failure
- Where
- 2 sites in Austria
- Volunteers
- 16 people
- Sponsor
- Ludwig-Boltzmann Institut fuer Rheumatologie, Balneologie und Rehabilitation
Diabetes, Arrhythmias
Association Between Cardiac ARRHYTHMIAs and Glycemic Variability in Patient With Type 2 Diabetes Monitored Through FREEstyle Libre and Bluetooth Technology.
The aim of this study is to investigate the association between hypoglycemia, glycemic variability and cardiac arrhythmias in patients with diabetes Type II (T2D) already implanted with implantable cardiac defibrillator (ICD) and…
- Conditions
- Diabetes, Arrhythmias, Atrial Fibrillation, Heart Failure
- Trial name
- ARRHYTHMIAFREE (NCT05994755)
- Where
- Italy
- Volunteers
- 58 people
- Sponsor
- Antonio Rapacciuolo
Chronic Heart Failure
Cardiac Strains for Optimization of CRT in Non-Responders
The aim of this study is to investigate the possibility of optimizing the performance of CRT-D in non-responding patients through utilization of cardiac strain speckle tracking
- Trial name
- NCT03803826
- Testing
- CRT-D re-programming, Trans-Thoracic Echocardiography
- Where
- Czechia
- Volunteers
- 50 people
- Sponsor
- University Hospital Ostrava
Myocardial Infarction, Acute
Effect of INtravenous FERRic Carboxymaltose Onmortality and Cardiovascular Morbidity, and Quality of Life in Iron Deficient Patients With Recent Myocardial infarCTion
Non-commercial, multicentre, randomised, double-blind, parallel group, placebo-controlled clinical trial. Eligible patients were randomly assigned (1:1) using a secure, central, interactive, web-based response system, to…
- Trial name
- INFERRCT (NCT05759078)
- Testing
- Ferinject, Sodium Chloride 0.9% Inj
- Where
- 43 sites in Poland
- Volunteers
- 1,000 people
- Sponsor
- Wroclaw Medical University
Right Heart Failure
Serial Multiparametric Evaluation of Right Ventricular Function After Left Ventricular Assist Device Implantation
The primary purpose of this study is to investigate the evolution of Right Ventricular (RV) function before and after left ventricular assist device (LVAD) implantation, using novel echocardiographic quantification of RV size and…
- Trial name
- EuroEchoVAD (NCT03552679)
- Testing
- Echocardiography
- Where
- 9 sites in Germany, Hungary and 5 more
- Volunteers
- 600 people
- Sponsor
- Erasmus Medical Center
Heart Failure, Acute Heart Failure
Acetazolamide in Patients With Acute Heart Failure
Introduction: Recent studies have suggested that the use of acetazolamide may assist in the vol- ume management of patients with decompensated heart failure (HF).
- Trial name
- ACETA (NCT03720288)
- Testing
- Acetazolamide
- Where
- Brazil
- Volunteers
- 90 people
- Sponsor
- University of Sao Paulo General Hospital
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