Clinical trials: Heart Failure, Unspecified
Congestive Heart Failure
Remote Monitoring of Chronic Heart Failure in Veneto Region
The purpose of this study is to evaluate whether telemonitoring of patients with chronic heart failure produces a reduction in the combined end point of all cause mortality and number of hospitalisations, and whether it improves…
- Trial name
- NCT01513993
- Testing
- Telemonitoring for patients with Congestive Heart Failure
- Where
- 8 sites in Italy
- Volunteers
- 315 people
- Sponsor
- Regione Veneto
Congenital Heart Disease, Cardiomyopathies
Cardiac Rehabilitation for Young People
Heart problems are amongst the most common physical illnesses in children and young people (CYP). They can be present from birth or develop as CYP get older and are linked to increased physical and psychological difficulties…
- Conditions
- Congenital Heart Disease, Cardiomyopathies, Cardiac Arrythmias, Heart Failure
- Trial name
- CardioActive (NCT05968521)
- Testing
- Cardiac Rehabilitation (CR): Experimental, Treatment as usual: Control
- Where
- United Kingdom
- Volunteers
- 100 people
- Sponsor
- Greater Manchester Mental Health NHS Foundation Trust
Heart Failure
Clinical Validation Study for CPM Device
This study is designed to be a clinical validation study to ready the CPM System for FDA 510(k) submission. This study will be conducted as a prospective non-randomized.
- Trial name
- NCT05445206
- Testing
- CardioPulmonary Management Device (CPM)
- Where
- United States
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Analog Device, Inc.
Chronic Obstructive Pulmonary Disease, Chronic Heart Failure
Using NT-proBNP to Detect Chronic Heart Failure in Patients With Chronic Obstructive Pulmonary Disease
The aim of the present study was to evaluate if the analysis of NT-proBNP might be used as an initial step for the diagnosis of chronic heart failure in patients with COPD in primary health care, and to select patients for a…
- Trial name
- NT-proBNP (NCT01801722)
- Where
- Sweden
- Volunteers
- 75 people
- Sponsor
- Lund University
Coronary Artery Disease (CAD) (E.G., Angina, Myocardial Infarction, and Atherosclerotic Heart Disease (ASHD)), Chronic Heart Failure
TELEREHAB-BR: Cardiovascular Rehabilitation Models Trial
Introduction: Cardiovascular diseases remain the leading cause of mortality worldwide. Despite the proven effectiveness of cardiac rehabilitation (CR) programs, adherence remains unsatisfactory, especially in public healthcare…
- Conditions
- Coronary Artery Disease (CAD) (E.G., Angina, Myocardial Infarction, and Atherosclerotic Heart Disease (ASHD)), Chronic Heart Failure, Acute Coronary Syndromes (ACS)
- Trial name
- TELEREHAB-BR (NCT07734831)
- Testing
- Hybrid Cardiac Telerehabilitation, Traditional Center-Based Cardiac Rehabilitation (TCR), Usual Care Group
- Where
- Brazil
- Volunteers
- 219 people
- Sponsor
- University of the State of Santa Catarina
Chronic Heart Failure
Effects of a Home-based Exercise Program on Functional Capacity and Quality of Life in Heart Failure Patients
Heart failure (HF) is a multisystemic disease leading to exercise intolerance and fatigue. Supervised physical training improves functional capacity, quality of life and reduces hospital admissions in HF patients.
- Trial name
- NCT03615157
- Testing
- Exercise rehabilitation
- Where
- 2 sites in Brazil
- Volunteers
- 30 people
- Sponsor
- University of Sao Paulo
Heart Failure
The Role of Bioimpedance Analysis in Patients With Chronic Heart Failure and Systolic Ventricular Dysfunction
Heart failure (HF) represents a major problem in today's health care landscape and is expected to grow in the next years due to an aging population and improved treatments.
- Trial name
- NCT05631275
- Where
- Spain
- Volunteers
- 100 people
- Sponsor
- Instituto de Investigación Sanitaria de la Fundación Jiménez Díaz
Heart Failure
The Effects of Sacubitril/Valsartan Compared to Valsartan on LV Remodelling in Asymptomatic LV Systolic Dysfunction After MI
Prior to reperfusion therapy, the major therapeutic breakthrough in myocardial infarction was the demonstration that ACE inhibitors or ARBs, given to prevent adverse "remodelling" (progressive dilatation and decline in systolic…
- Trial name
- RECOVER-LV (NCT03552575)
- Testing
- sacubitril/valsartan, Valsartan
- Where
- 2 sites in United Kingdom
- Volunteers
- 93 people
- Sponsor
- NHS Greater Glasgow and Clyde
Heart Failure With Preserved Ejection Fraction, Malnutrition
A Single-center Retrospective Cohort Study to Explore the Prognostic Significance of CONUT in Elderly CAD Patients With HFpEFand Compare CONUT With Other Objective Nutritional Indices.
HF is an advanced or terminal stage of various heart diseases, with high rehospitalization and mortality rates. In HF patients, undernutrition is not uncommon and represents one of the most significant determinants of poor…
- Conditions
- Heart Failure With Preserved Ejection Fraction, Malnutrition, Aged, Prognosis
- Trial name
- NCT05586828
- Where
- China
- Volunteers
- 780 people
- Sponsor
- Beijing Tongren Hospital
Drug Use, Alcohol Use
Specialized Community Disease Management to Reduce Substance Use and Hospital Readmissions
This study will assess Specialized Community Disease Management (SCDM), an intervention which employs various evidence-based strategies to engage substance using co-morbid patients while in the hospital and follow them into the…
- Conditions
- Drug Use, Alcohol Use, Congestive Heart Failure, Pneumonia
- Trial name
- NCT02059005
- Testing
- Specialized Community Disease Management, Treatment As Usual
- Where
- United States
- Volunteers
- 97 people
- Sponsor
- Treatment Research Institute
Hyponatremia
Study of Ascending Levels of Tolvaptan in Hyponatremia
The purpose of this study was to determine whether tolvaptan can safely and effectively return the body's balance of sodium and water toward normal and to characterize and quantify the potential clinical benefits of this…
- Trial name
- SALT2 (NCT00201994)
- Testing
- Tolvaptan
- Where
- Germany
- Volunteers
- 243 people
- Sponsor
- Otsuka Pharmaceutical Development & Commercialization, Inc.
Heart Failure, Diastolic Heart Failure
ST2 for the Management of Heart Failure - STADE-HF
Heart failure (HF) is a severe disease, burdened with a poor prognosis (30% mortality at 2 years, 30% of rehospitalization within 1 month).
- Conditions
- Heart Failure, Diastolic Heart Failure, Systolic Heart Failure Stage C
- Trial name
- STADE-HF (NCT02963272)
- Testing
- Conventional strategy, ST2-guided strategy
- Where
- France
- Volunteers
- 123 people
- Sponsor
- University Hospital, Montpellier
Sarcopenia, Muscular Atrophy
The Effects of Home-based Physical Activity Telemonitoring Program in Patients With Heart Failure and Muscle Wasting
Introduction： Muscle wasting is a serious complication that affects a large proportion of patients with heart failure (HF). Muscle wasting is a strong predictor of frailty and reduced survival in HF patients.
- Conditions
- Sarcopenia, Muscular Atrophy, Wasting Syndrome, Heart Failure
- Trial name
- NCT05588375
- Testing
- home-based physical activity telemonitoring program
- Where
- Taiwan
- Volunteers
- 118 people
- Sponsor
- Far Eastern Memorial Hospital
Chronic Illness, NYHA Class II-IV Heart Failure
Addressing Pain Through Navigator-Led Palliative Care Optimized for Heart Failure (ADAPT-HF)
Using the MOST framework, factorial pilot design, and an iterative, community-based process, the purpose of this study is to pilot test to further develop and refine a palliative care (PC) intervention addressing pain of Black…
- Trial name
- ADAPT HF (NCT06270875)
- Testing
- ADAPT HF
- Where
- United States
- Volunteers
- 10 people
- Sponsor
- University of Alabama at Birmingham
Heart Failure With Preserved Ejection Fraction
The PeriCut Catheter System Early Feasibility Study (REIMAGINE-HFpEF)
The PeriCut early feasibility study will evaluate the safety and feasibility of successfully performing a minimally invasive pericardiotomy in patients with heart failure with preserved ejection fraction using the PeriCut…
- Trial name
- REIMAGINE-HF (NCT06702501)
- Testing
- PeriCut Catheter System performs minimally invasive pericardiotomy
- Where
- United States
- Volunteers
- 10 people
- Sponsor
- Heart Failure Solutions, Inc.
HFpEF - Heart Failure With Preserved Ejection Fraction
MOVE-HF MOtivating Physical Activity With BehaVioral Economics in Heart Failure With Preserved Ejection Fraction
This is a three-arm, randomized, controlled trial to test the effectiveness of gamification plus a social incentive - either social support or competition - to increase adherence to physical activity among individuals with HFpEF.
- Trial name
- NCT06670001
- Testing
- Gamification plus social incentive, Gamification plus competition
- Where
- United States
- Volunteers
- 270 people
- Sponsor
- University of Pennsylvania
Worsening Chronic Heart Failure, Chronic Kidney Disease
A Study to Learn How BAY94-8862 Moves Into, Through and Out of the Body, How Safe it is and How it Affects the Body in Adult Participants With Reduced Kidney Function and in Healthy Participants With Similar Age, Weight and Gender Distribution
Researchers are looking for a better way to treat people who have worsening of chronic heart failure, a long-term condition where the heart does not pump blood as well as it should.
- Trial name
- NCT04908436
- Testing
- Finerenone (BAY94-8862)
- Where
- Germany
- Volunteers
- 33 people, healthy volunteers welcome
- Sponsor
- Bayer
Advance Care Planning, Heart Failure
Development and Evaluation of 'My Voice': A Randomized Controlled Trial
The study aims to develop and evaluate a web-based interactive platform (called 'My Voice') that helps to educate patients with heart failure and their caregivers about heart failure, identify their goals for end-of-life care…
- Trial name
- NCT06090734
- Testing
- My Voice
- Where
- Singapore
- Volunteers
- 244 people
- Sponsor
- Duke-NUS Graduate Medical School
Heart Failure, Tachypnea
Akershus Cardiac Examination 4 Study
Patients hospitalized with tachypnea, defined as respiratory rate ≥20/ min, have substantial mortality and may suffer from different conditions, including acute heart failure (HF).
- Trial name
- ACE4 (NCT05699564)
- Testing
- Early biomarker-based cardiological assessment
- Where
- Norway
- Volunteers
- 574 people
- Sponsor
- University Hospital, Akershus
Atrial Fibrillation, Heart Failure
A Village Doctor-led Telehealth Supported Trial of Heart Failure Prevention in AF Patients: MIRACLE-AF 2 (Heart Failure Prevention)
This cluster randomized study aims to compare village doctor-led integrated care versus usual care to improve cardiovascular health, atrial fibrillation management, self-management adherence, and heart failure prevention among…
- Trial name
- NCT07492498
- Testing
- Village-Doctor Led Integrated Care, Usual Care
- Where
- 3 sites in China
- Volunteers
- 1,356 people
- Sponsor
- Jiangsu Taizhou People's Hospital
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