Clinical trials: Heart Failure，Congestive
Dementia, Chronic Disease
Project to Improve Communication About Serious Illness--Hospital Study: Pragmatic Trial (Trial 1)
The objective of this protocol is to test the effectiveness of a Jumpstart intervention on patient-centered outcomes for patients with chronic illness by ensuring that they receive care that is concordant with their goals over…
- Conditions
- Dementia, Chronic Disease, Neoplasm Metastasis, Lung Neoplasm
- Trial name
- PICSI-H (NCT04281784)
- Testing
- EHR-based Clinician Jumpstart
- Where
- 3 sites in United States
- Volunteers
- 2,512 people
- Sponsor
- University of Washington
Congestive Heart Failure, Copd
A Mobile Integrated Health Intervention to Manage Congestive Health Failure and Chronic Obstructive Pulmonary Disease
Episodic and disjointed medical care for older, community-dwelling adults with chronic obstructive pulmonary disease (COPD) and congestive heart failure (CHF) leave them vulnerable to adverse events such as worsening disease…
- Trial name
- NCT05540158
- Testing
- Mobile Integrated Health Intervention
- Sponsor
- University of Massachusetts, Worcester
COVID-19 Pandemic, Pulmonary Disease, Chronic Obstructive
COVID-19, Patients' Evolution and the Influence of the Pandemic on Health Care and Outcomes in Chronic Diseases
Objectives: 1.- To evaluate the changes in health care and use of services in patients with chronic diseases such as chronic obstructive pulmonary disease (COPD), heart failure and major depression between 2017-2019 and the years…
- Conditions
- COVID-19 Pandemic, Pulmonary Disease, Chronic Obstructive, Heart Failure, Congestive, Depressive Symptoms
- Trial name
- NCT05168722
- Testing
- No interventions
- Where
- 5 sites in Spain
- Volunteers
- 2,220 people
- Sponsor
- Hospital Galdakao-Usansolo
Heart Failure，Congestive
RELieving Increasing oEdema Due to Heart Failure
This trial will investigate the potential for patiromer-facilitated use of higher doses of mineralocorticoid antagonists in addition to standard care (compared to standard care alone) to improve congestion, well-being and…
- Trial name
- RELIEHF (NCT04142788)
- Testing
- Patiromer
- Where
- 11 sites in United Kingdom
- Volunteers
- 19 people
- Sponsor
- NHS Greater Glasgow and Clyde
Heart Failure, Left-Sided Heart Failure
CardioMEMS HF System OUS Post Market Study
The purpose of this Post Market Study (PMS) is to evaluate the use of the CardioMEMS HF System in patients with New York Heart Association (NYHA) Class III Heart Failure in a commercial setting.
- Conditions
- Heart Failure, Left-Sided Heart Failure, Congestive Heart Failure
- Trial name
- NCT02954341
- Testing
- CardioMEMS HF System
- Where
- 5 sites in Australia, Belgium and 3 more
- Volunteers
- 321 people
- Sponsor
- Abbott Medical Devices
Diabetic Retinopathy, Macular Degeneration
Advancing Understanding of Transportation Options
This Stage II randomized, controlled, longitudinal trial seeks to assess the acceptability, feasibility, and effects of a driving decision aid use among geriatric patients and providers.
- Conditions
- Diabetic Retinopathy, Macular Degeneration, Glaucoma, Retinitis Pigmentosa
- Trial name
- AUTO (NCT04141891)
- Testing
- Driving Decision Aid, Older Drivers Website
- Where
- 3 sites in United States
- Volunteers
- 529 people, healthy volunteers welcome
- Sponsor
- University of Colorado, Denver
Heart Failure with Reduced Ejection Fraction, Heart Failure
Prediction of Heart-Failure with Machine Learning
In this monocentric observational study the research question is to what extent data collected via Apple Watch can predict the heart failure status of decompensated HF patients.
- Conditions
- Heart Failure with Reduced Ejection Fraction, Heart Failure, Heart Failure，Congestive, Heart Failure Acute
- Trial name
- PRE-HF-ML (NCT06819618)
- Testing
- Monitoring with Apple Watch
- Where
- Germany
- Volunteers
- 32 people
- Sponsor
- University Medical Center Goettingen
Chronic Disease, Neoplasm Metastasis
Facilitating Communication Study
This study is a randomized clinical trial of an intervention to improve outcomes for patients and their family by using ICU nurse facilitators to support, model, and teach communication strategies that enable patients and their…
- Conditions
- Chronic Disease, Neoplasm Metastasis, Lung Neoplasm, Pulmonary Disease, Chronic Obstructive
- Trial name
- FCS2 (NCT03721952)
- Testing
- Facilitator-Based Intervention
- Where
- 3 sites in United States
- Volunteers
- 977 people
- Sponsor
- University of Washington
Fluid Overload, Congestive Heart Failure
THIRST Alert Trial
The aim of this feasibility study is to determine whether an alert embedded within the electronic health record (EHR) causes clinicians to enrol patients into a randomised controlled trial (RCT) comparing oral fluid restriction…
- Trial name
- THIRST (NCT05869656)
- Testing
- Fluid restriction, Free fluids
- Where
- United Kingdom
- Volunteers
- 23 people
- Sponsor
- University College, London
Pediatric ALL, Congenital Heart Disease
Virtual Remote Physiological Monitoring Program of Children With Heart Disease
Infants and children with heart conditions require treatment in children's hospitals that are typically located in large cities.
- Conditions
- Pediatric ALL, Congenital Heart Disease, Single-ventricle, Biventricular Congestive Heart Failure
- Trial name
- NCT05034354
- Testing
- Remote physiological monitoring
- Where
- Canada
- Volunteers
- 23 people
- Sponsor
- University of Alberta
Cardiomyopathy, Cardiovascular Diseases
Improving Mitral Repair for Functional Mitral Regurgitation
The investigators are interested in determining the best surgical technique to correct functional mitral regurgitation, as there is currently not one technique that is established to work better than the other.
- Conditions
- Cardiomyopathy, Cardiovascular Diseases, Congestive Heart Failure, Coronary Artery Disease
- Trial name
- IMPROVE-FMR (NCT03366649)
- Testing
- Undersizing Mitral Annuloplasty, Papillary Muscle Approximation
- Where
- 3 sites in United States
- Volunteers
- 34 people
- Sponsor
- Emory University
Heart Failure，Congestive
Comparison of Non-invasive Vs. Invasive Hemodynamic Measurements
Comparison of a non-invasive method of measuring central venous pressure to the conventional modality of invasive central venous pressure.
- Trial name
- NCT04180202
- Testing
- Non-invasive central venous pressure
- Where
- United States
- Volunteers
- 8 people
- Sponsor
- Nihon Kohden
Congestive Heart Failure
Study for the Evaluation of a Non-invasive Hemodynamic Measurement in Heart Failure Patients
Track changes in non-invasive central venous pressure across hospital stay and relationship with readmission
- Trial name
- NCT05441696
- Testing
- ezCVP measurement
- Where
- 2 sites in United States
- Volunteers
- 65 people
- Sponsor
- Nihon Kohden
Heart Failure; With Decompensation, Lower Extremity Edema
Above-Knee-High Application of Lower Limb Compression and Its Impact on Clinical Outcome in Patients Hospitalized With Heart Failure Exacerbation.
Heart failure (HF) remains one of the most common causes of hospitalization with high morbidity and mortality, and its worldwide prevalence is increasing.
- Conditions
- Heart Failure; With Decompensation, Lower Extremity Edema, Heart Failure，Congestive
- Trial name
- A-KHALIFE (NCT05467735)
- Testing
- Application of compression to bilateral lower extremities of patients using appropriately-sized elastic compression stockings.
- Where
- United States
- Volunteers
- 20 people
- Sponsor
- The University of Texas Medical Branch, Galveston
Coronary Heart Disease (CHD), Cardio-pulmonary Bypass
Protective Effect of EECP Against Negative Inflammatory Response and Organ Dysfunction After Cardiovascular Surgery
Enhanced external counterpulsation (EECP) is a noninvasive, non-pharmacologic intervention proven to increase nitric oxide bioavailability in patients with coronary artery disease.
- Conditions
- Coronary Heart Disease (CHD), Cardio-pulmonary Bypass, Congestive Heart Failure Chronic, Cardiogenic Shock Acute
- Trial name
- PANDA (NCT06728605)
- Testing
- Enhanced External Counterpulsation (EECP)
- Where
- China
- Volunteers
- 400 people
- Sponsor
- Nanjing Medical University
Diabetes, Asthma
Integrated Care (IC) Models for Patient-Centered Outcomes
Multiple chronic conditions (MCC) are widely recognized as the U.S. public health challenge of the 21st century. These physical and behavioral health conditions take a large toll on those living with chronic diseases, including…
- Conditions
- Diabetes, Asthma, Chronic Obstructive Pulmonary Disease, Hypertension
- Trial name
- IC (NCT03451630)
- Testing
- High-Touch, High-Tech, Optimal Discharge Planning
- Where
- United States
- Volunteers
- 1,400 people, healthy volunteers welcome
- Sponsor
- University of Pittsburgh
Congestive Heart Failure, Defibrillators
Verifying Remote Monitoring Effect on Net Cardiovascular Outcome; RemoteVerify (RêVe)
This study investigates the impact and safety of wireless monitoring on the prognosis of heart failure patients with implanted pacemakers and defibrillators.
- Conditions
- Congestive Heart Failure, Defibrillators, Cardiac Resynchronization Therapy
- Trial name
- ReVe (NCT05971225)
- Testing
- remote monitoring only
- Where
- South Korea
- Volunteers
- 450 people
- Sponsor
- Saint Vincent's Hospital, Korea
Congestive Heart Failure
Cohort of Heart Failure Patients
This is a prospective cohort study of patients with Heart Failure with an eighteen-month follow-up aimed to collect all demographic, clinical, biological and para-clinical data to study population characteristics, assess…
- Trial name
- LOOP-HF (NCT03422991)
- Testing
- Blood sampling and Quality of life questionnaire.
- Where
- France
- Volunteers
- 150 people
- Sponsor
- Hospices Civils de Lyon
Heart Failure，Congestive
Dapagliflozin on Volume Vascular Outcomes.
The purpose of the DAPA-VOLVO trial is to investigate the effects of Dapagliflozin on top of recommended standard therapy on volume status and vascular function in clinically stable de novo or chronic heart failure patients after…
- Trial name
- DAPA-VOLVO (NCT04869124)
- Testing
- Dapagliflozin
- Where
- Switzerland
- Volunteers
- 80 people
- Sponsor
- Frank Ruschitzka
Congestive Heart Failure (CHF)
Evaluation of the Use of Empagliflozin in Patients with HF with PEF in a Cardiology Outpatient Department
This study aims to evaluate whether the use of a 25 mg dose of empagliflozin compared to the 10 mg dose used would bring additional benefits in the improvement outcomes of the Kansas City Cardiomyopathy Questionnaire (KCCQ SST)…
- Trial name
- ADDEMFEP (NCT06683053)
- Testing
- empagliflozin
- Where
- Brazil
- Volunteers
- 90 people
- Sponsor
- Conrado Roberto Hoffmann Filho