Clinical trials: Heart Failure (HF)
Heart Failure and ST Elevation Myocardial Infarction
Predictors of Heart Failure After ST-segment Elevation Myocardial Infarction (HF-EXPRESS)
Objective: The purpose of this project is to study the post miyocardial infaction (MI) damage and subsequently developed post-infarct cardiac repair process on the basis of cellular, molecular and imaging techniques.
- Trial name
- HF-EXPRESS (NCT02650934)
- Testing
- Percutanous coronary intervention
- Where
- Turkey (Türkiye)
- Volunteers
- 312 people
- Sponsor
- Dr. Nafiz Korez Sincan State Hospital
Heart Failure, Central Sleep Apnea
The Impact of Low Flow Nocturnal Oxygen Therapy on Hospital Admissions and Mortality in Patients With Heart Failure and Central Sleep Apnea
The purpose of this trial is to evaluate the long-term effects of Nocturnal Oxygen Therapy (NOXT) on the mortality and morbidity of patients with stable heart failure and a reduced ejection fraction (HFrEF), already receiving…
- Trial name
- NCT03745898
- Testing
- Oxygen, Room Air
- Where
- 26 sites in United States
- Volunteers
- 98 people
- Sponsor
- Brigham and Women's Hospital
Type2 Diabetes, Heart Failure
Impact of a Short-term Treatment With Canagliflozin (Canacardia-HF)
It is a mechanistic proof-of-concept study to demonstrate how SGLT-2 inhibitors (Canagliflozin) may have a beneficial role on cardiac energetic efficiency.
- Trial name
- Canacardia (NCT03298009)
- Testing
- Canagliflozin 100mg, PET imaging
- Sponsor
- Université de Sherbrooke
Chronic Heart Failure
Survival Study of the Recombinant Human Neuregulin-1β in Subjects With Chronic Heart Failure.
The purpose of this study is to evaluate efficacy of rhNRG-1 in reducing the death rate of heart failure subjects with baseline NT-proBNP level between 600 pg/ml and 1700 pg/mL and NYHA class II to III.
- Trial name
- NCT03388593
- Testing
- rhNRG-1
- Where
- 65 sites in China
- Volunteers
- 1,600 people
- Sponsor
- Zensun Sci. & Tech. Co., Ltd.
Heart Failure (HF), Self Care
Evaluation of Remote Motivational Interviewing for Disease Management in Heart Failure Patients and Their Carers
Heart failure (HF) is a chronic and progressive condition that significantly affects patients' quality of life and increases the burden on family caregivers.
- Conditions
- Heart Failure (HF), Self Care, Caregiver, Motivational Interviewing (MI)
- Trial name
- REMIND-HF (NCT07413419)
- Testing
- Remote Motivational Interviewing, Standard Heart Failure Care
- Where
- Poland
- Volunteers
- 600 people
- Sponsor
- Wroclaw Medical University
Heart Failure
Acorai Machine Learning Generalization (MLG) Study
Acorai is developing a non-invasive monitoring system for the estimation of intracardiac hemodynamic parameters in patients with suspected or confirmed heart failure, and/or pulmonary hypertension, who require hemodynamic…
- Trial name
- CAPTURE-HF (NCT05835024)
- Testing
- Acorai Sensor Data Collection (ASDC) system 1.0 - Phase 1, Acorai Sensor Data Collection (ASDC) system 1.0 - Phase 2
- Where
- 18 sites in United States, Belgium and 4 more
- Volunteers
- 1,602 people, healthy volunteers welcome
- Sponsor
- Acorai AB
Heart Failure With Preserved Ejection Fraction (HFpEF), Heart Failure With Mildly Reduced Ejection Fraction (HFmrEF)
A Study to Investigate CV Outcomes With Elecoglipron Compared With Placebo in Adult Participants With HFpEF or HFmrEF
This is a Phase III, randomized, double-blind, parallel-group, placebo-controlled, multicenter study to investigate CV outcomes with elecoglipron compared with placebo, in adults with heart failure with preserved ejection…
- Trial name
- Elevate-HF (NCT07761117)
- Testing
- Elecoglipron
- Where
- 679 sites in United States, Argentina and 30 more
- Volunteers
- 6,950 people
- Sponsor
- AstraZeneca
Heart Failure
The Impact of Comprehensive Post Hospital Management Based on DHI on Cardiac Function in Patients With HF
Due to the complex nature of HF patients' conditions, long-term treatment and management are required, especially post hospital management, which is of great significance for improving patients' cardiac function and quality of…
- Trial name
- NCT06947148
- Testing
- Comprehensive post hospital management based on digital health intervention(DHI)
- Where
- China
- Volunteers
- 104 people
- Sponsor
- Harbin Medical University