Clinical trials: Heart Failure Hospitalization
COPD, Severe or Very Severe Airflow Obstruction and/or Receiving or Eligible to Receive Long-term Oxygen Therapy
Study of Default Options in Advance Directives
Default options represent the events or conditions that are set into place if no alternatives are actively chosen. The setting of default options has well-established effects on a broad range of human decisions, but its influence…
- Conditions
- COPD, Severe or Very Severe Airflow Obstruction and/or Receiving or Eligible to Receive Long-term Oxygen Therapy, Idiopathic Pulmonary Fibrosis, Other Interstitial Lung Disease Without Curative Therapy
- Trial name
- NCT01817686
- Testing
- Comfort Default AD forms, Life Extension Default AD forms, Standard Default AD forms
- Where
- United States
- Volunteers
- 62 people
- Sponsor
- Corporal Michael J. Crescenz VA Medical Center
Heart Failure
Prolonged Intravenous Therapy Versus Early Initiation of an Oral Loop Diuretic in Decompensated Heart Failure
The goal of this clinical study is to compare treatment regimens of loop diuretics in patients with decompensated heart failure.
- Trial name
- NCT05652322
- Testing
- Furosemide Pill 150% equivalent iv dose, Furosemide Pill 200% equivalent iv dose, Furosemide Injection
- Where
- 3 sites in Poland
- Sponsor
- Jan Kochanowski University
Hypertension, Coronary Disease
Analyzing How Genetics May Affect Response to High Blood Pressure Medications
High blood pressure is one of the most common health problems in the United States. There are many medications to treat high blood pressure, but there is a large variance in how people respond to these medications.
- Conditions
- Hypertension, Coronary Disease, Cerebrovascular Accident
- Trial name
- NCT00563901
- Where
- 2 sites in United States
- Volunteers
- 37,939 people, healthy volunteers welcome
- Sponsor
- University of Alabama at Birmingham
Acute Heart Failure, Pulmonary Congestion
LUS in Acute Heart Failure Therapeutic Adaptation
Evaluate lung ultrasound aspect according to diuretics dosage evolution in patients hospitalized for acute heart failure.
- Trial name
- EPPICA (NCT04633629)
- Testing
- Lung ultrasound
- Volunteers
- 94 people
- Sponsor
- University Hospital, Grenoble
Acute Respiratory Distress Syndrome, Coronavirus
Pemziviptadil (PB1046), a Long-acting, Sustained Release Human VIP Analogue, Intended to Provide Clinical Improvement to Hospitalized COVID-19 Patients at High Risk for Rapid Clinical Deterioration and Acute Respiratory Distress Syndrome (ARDS).
This is a multicenter, randomized, double-blind, parallel group study to investigate the efficacy of pemziviptadil (PB1046) by improving the clinical outcomes in hospitalized COVID-19 patients at high risk for rapid clinical…
- Conditions
- Acute Respiratory Distress Syndrome, Coronavirus, Hypoxic Respiratory Failure, Hypoxemic Respiratory Failure
- Trial name
- VANGARD (NCT04433546)
- Testing
- Pemziviptadil (PB1046), Low Dose (10 mg) Control
- Where
- 4 sites in United States
- Volunteers
- 54 people
- Sponsor
- PhaseBio Pharmaceuticals Inc.
Diabetes, Heart Failure
Avoidable Hospitalizations/ Emergency Department Visits- Systematic Review and Meta-synthesis of Qualitative Research
The aim of the study is to synthesize qualitative evidence related to preventable hospitalizations/ emergency department visits from the perspectives of patients, their families/caregivers, health care providers, and…
- Conditions
- Diabetes, Heart Failure, Chronic Obstructive Pulmonary Disease, Asthma
- Trial name
- NCT05456906
- Testing
- No intervention
- Where
- Taiwan
- Volunteers
- 30 people
- Sponsor
- Kaohsiung Medical University
Heart Failure With Reduced Ejection Fraction
This Study Will Evaluate the Efficacy and Safety of LCZ696 Compared to Enalapril on Morbidity and Mortality of Patients With Chronic Heart Failure
The study will evaluate the efficacy and safety of LCZ696 compared to enalapril on morbidity and mortality in patients with chronic heart failure (NYHA Class II - IV and EF =< 35%).
- Trial name
- PARADIGM-HF (NCT01035255)
- Testing
- LCZ696 200 mg BID, Enalapril 10 mg BID
- Where
- 1,031 sites in United States, Argentina and 45 more
- Volunteers
- 8,442 people
- Sponsor
- Novartis Pharmaceuticals
Acute Decompensated Heart Failure
A Study Of Acute Decompensated Heart Failure
The purpose of this study is to examine shorter hospitalization length as well as a reduced rates of recurrent heart failure hospitalization compared to current standard of care in Acute Decompensated Heart Failure.
- Trial name
- NCT07572955
- Testing
- Lung Ultrasound
- Where
- United States
- Volunteers
- 500 people
- Sponsor
- Mayo Clinic
Cardiac Resynchronisation Therapy (CRT), Heart Failure
Conduction System Pacing vs. Biventricular Pacing for Cardiac Resynchronization Therapy
The NORDIC-CSP trial is an investigator-initiated, blinded, nordic RCT aimed at evaluating whether using direct pacing of the HIS bundle (HIS)-pacing or left bundle branch (LBB) pacing is superior to conventional biventricular…
- Conditions
- Cardiac Resynchronisation Therapy (CRT), Heart Failure, Conduction System Pacing
- Trial name
- Nordic-CSP (NCT07492979)
- Testing
- HIS or LBBB -CRT, Conventional BiV-CRT
- Where
- 5 sites in Denmark, Finland and 2 more
- Volunteers
- 1,100 people
- Sponsor
- Copenhagen University Hospital, Rigshospitalet
Acute Heart Failure
Lithuanian Echocardiography Study of Dyspnea in Acute Settings
LEDA (Lithuanian Echocardiography study of Dyspnea in Acute settings) is a prospective observational cohort multicenter clinical study.
- Trial name
- LEDA (NCT03048032)
- Testing
- Blood sampling, Echocardiography exam
- Where
- 3 sites in France, Lithuania
- Volunteers
- 1,566 people
- Sponsor
- Vilnius University
Chronic Disease, Heart Failure
Chronic Disease Mobile Educational Experience
This study evaluates the effectiveness of a mobile health education module, in increasing hospitalized patients' understanding of their chronic illness, and in reducing 30-day hospital readmission rates.
- Trial name
- NCT04090593
- Testing
- Patient Education 101: Mobile Health Education Tool
- Volunteers
- 200 people
- Sponsor
- Los Angeles County Department of Public Health
Acute Heart Failure
Short Stay Unit vs Hospitalization in Acute Heart Failure
The majority of the over one million annual AHF hospitalizations originate from the emergency department. Admitting and re-admitting lower risk AHF patients who don't need prolonged hospitalization may increase their risk for…
- Trial name
- SSU-AHF (NCT03302910)
- Testing
- Short Stay Unit, Standard of Care
- Where
- 11 sites in United States
- Volunteers
- 194 people
- Sponsor
- Indiana University
Myocarditis, Sudden Cardiac Death
Occurrence, Trends, Management and Outcomes of Patients Hospitalized With Myocarditis
The epidemiology of myocarditis is largely unknown and based mainly on small single-center studies. The study aim to evaluate the current incidence, clinical characteristics and outcomes of patients hospitalized due to…
- Conditions
- Myocarditis, Sudden Cardiac Death, Cardiomyopathies, Arrythmia
- Trial name
- MYO-PL (NCT04827706)
- Where
- Poland
- Volunteers
- 19,978 people
- Sponsor
- Medical University of Warsaw
Cardiovascular Diseases
Low Health Literacy Prevalence's Study in Patients With Chronic Cardiovascular Disease
Health literacy is the ability to access, understand, evaluate and apply information in order to communicate with health professionals and understand health instructions but also, promote, maintain and improve health throughout…
- Trial name
- LIT-S (NCT03952013)
- Testing
- To explore health literacy levels in patients hospitalized for acute neuro-cardiovascular diseases i.e. stroke, myocardial infarction, or heart failure
- Sponsor
- Hospices Civils de Lyon
Heart Failure
Use of mHealth to Increase Physical Activity for Patients Recently Hospitalized With Acute Heart Failure
The aim of this trial is to determine if a mobile application that promotes physical exercise in the follow-up of patients recently hospitalized with acute heart failure can improve exercise capacity after 6 months and physical…
- Trial name
- mRehab (NCT04848298)
- Testing
- mHealth Intervention
- Where
- Spain
- Volunteers
- 116 people
- Sponsor
- Fundació Institut de Recerca de l'Hospital de la Santa Creu i Sant Pau
Acute Decompensated Heart Failure (ADHF)
Bedside Ultrasound-guided Volume Management and Discharge Timing for Patients With Heart Failure During Hospitalization: A Randomized Controlled Trial
Brief Summary of the POCUS-HF Study The goal of this clinical trial is to determine whether using bedside ultrasound (POCUS) to guide fluid management and discharge timing can improve outcomes for hospitalized heart failure (HF)…
- Trial name
- NCT07046169
- Testing
- Ultrasound-Guided Volume Assessment and Decongestion Strategy (UVADS), clinical assessment
- Where
- China
- Volunteers
- 150 people
- Sponsor
- Pan He
Diabetes
Use of CGM for Diabetes Management Following a Hospitalization.
Patients with diabetes hospitalized for heart failure or acute myocardial infarction will have a continuous glucose monitor (CGM) placed on the day of discharge which will be downloaded at their outpatient follow up clinic visit…
- Trial name
- NCT04149392
- Testing
- Continuous Glucose Monitor
- Sponsor
- University of Virginia
Heart Failure
Hospitalization at Home of Elderly Patients With Heart Failure
Aim of the study was to evaluate the efficacy of hospital-at-home treatment compared with inpatient care in selected elderly patients with acute exacerbation of chronic heart failure (CHF).
- Trial name
- NCT00623571
- Testing
- Treatment of elderly patients in a GMW, Treatment of elderly patients in GHHS
- Where
- Italy
- Volunteers
- 101 people
- Sponsor
- Azienda Ospedaliera San Giovanni Battista
Heart Failure, COPD
Potentially Avoidable Hospitalisation in France
Potentially Avoidable Hospitalizations (Pah) Are Studied As An Indirect Measure Of Access To Primary Care And Of The Interface Between Primary And Secondary Care.
- Conditions
- Heart Failure, COPD, Diabetes
- Trial name
- HPE-LR (NCT02898155)
- Testing
- measure of access to primary care and of the Interface Between Primary ans Secondary Care
- Where
- France
- Volunteers
- 12,000 people
- Sponsor
- University Hospital, Montpellier
Heart Failure
Monitoring Oedema in Heart Failure to Improve Function and Reduce Hospitalisation Risk
This study will evaluate the Heartfelt device, a novel, passive monitoring system that detects early signs of fluid build-up in patients (oedema) with heart failure by measuring changes in foot and lower leg volume through…
- Trial name
- ME-HF (NCT07067658)
- Testing
- Installation of Heartfelt Device, Enhanced Standard care, Questionnaires
- Where
- 18 sites in United Kingdom
- Volunteers
- 300 people
- Sponsor
- Heartfelt Technologies